IRIS
BARALDI, Pier Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 27.679
EU - Europa 9.361
AS - Asia 4.952
SA - Sud America 36
OC - Oceania 29
Continente sconosciuto - Info sul continente non disponibili 27
AF - Africa 11
Totale 42.095
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Nazione #
US - Stati Uniti d'America 27.635
CN - Cina 2.936
DE - Germania 2.668
UA - Ucraina 2.238
TR - Turchia 1.691
GB - Regno Unito 948
IT - Italia 840
SE - Svezia 801
BE - Belgio 510
FI - Finlandia 477
RU - Federazione Russa 429
FR - Francia 154
VN - Vietnam 117
PL - Polonia 114
AT - Austria 65
IN - India 39
HK - Hong Kong 34
CA - Canada 28
KR - Corea 28
EU - Europa 24
AU - Australia 22
CZ - Repubblica Ceca 22
JP - Giappone 21
NL - Olanda 21
IR - Iran 19
TW - Taiwan 19
MX - Messico 16
CL - Cile 14
IL - Israele 14
RO - Romania 10
CO - Colombia 9
BR - Brasile 8
CH - Svizzera 8
HU - Ungheria 8
MY - Malesia 7
NO - Norvegia 7
NZ - Nuova Zelanda 7
ES - Italia 6
ID - Indonesia 6
PK - Pakistan 5
PT - Portogallo 5
BG - Bulgaria 4
GR - Grecia 4
IE - Irlanda 4
IQ - Iraq 4
ZA - Sudafrica 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AR - Argentina 3
BD - Bangladesh 3
EG - Egitto 3
HR - Croazia 3
LT - Lituania 3
MA - Marocco 3
MD - Moldavia 3
DK - Danimarca 2
LU - Lussemburgo 2
TH - Thailandia 2
AE - Emirati Arabi Uniti 1
EC - Ecuador 1
IM - Isola di Man 1
KH - Cambogia 1
LK - Sri Lanka 1
MC - Monaco 1
ME - Montenegro 1
MN - Mongolia 1
NP - Nepal 1
PE - Perù 1
PH - Filippine 1
RS - Serbia 1
SG - Singapore 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
Totale 42.095
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Città #
Woodbridge 3.792
Fairfield 3.594
Jacksonville 2.451
Houston 2.445
Chandler 2.077
Ann Arbor 1.914
Ashburn 1.648
Seattle 1.499
Wilmington 1.382
Cambridge 1.093
Izmir 799
Nanjing 771
Beijing 538
Princeton 512
Brussels 509
Boardman 343
San Diego 322
Shenyang 266
Ferrara 261
Nanchang 212
Milan 179
Hebei 158
San Mateo 154
Bremen 144
Addison 142
Tianjin 141
Changsha 139
Jiaxing 122
Dearborn 114
Dong Ket 114
Philadelphia 110
Jinan 106
Warsaw 104
Falls Church 86
Norwalk 83
Redwood City 78
Kunming 76
Zhengzhou 70
London 61
Mountain View 59
Ningbo 50
Auburn Hills 47
Orange 47
Verona 41
Vienna 41
Guangzhou 38
Des Moines 37
Indiana 37
Munich 35
Taizhou 34
Lanzhou 32
Tappahannock 28
Hong Kong 26
Chicago 25
Hangzhou 25
Paris 25
Shanghai 25
Washington 25
Düsseldorf 22
Mcallen 22
New York 22
Redmond 22
Augusta 20
Haikou 20
Los Angeles 20
Montréal 20
Taipei 19
Helsinki 18
Brno 15
Duncan 15
Leawood 15
Hefei 14
San Francisco 14
Xian 13
Bari 12
Monmouth Junction 12
Chiswick 11
Fuzhou 11
Yellow Springs 11
Ardabil 10
New Bedfont 10
Corvallis 9
Taiyuan 9
Padova 8
Palo Alto 8
Prescot 8
Changchun 7
Acton 6
Bologna 6
Budapest 6
Hounslow 6
Medellín 6
Oslo 6
Rome 6
San Jose 6
Chengdu 5
Dallas 5
Englewood 5
Ensenada 5
Hanover 5
Totale 29.776
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Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 286
1,4-Diketones via Isoxazole Intermediates 271
1,2,3-triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: A new class of A(2A) adenosine receptor antagonists 238
null 227
A glance at adenosine receptors: Novel target for antitumor therapy 196
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 164
The A3 adenosine receptor: history and perspectives 158
Active γ-manganese dioxide promoted conversion of 4,5-dihydro-1,2-oxazoles to 1,2-oxazoles. 152
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 151
Azaprostaglandin Analogues. Synthesis and Biological Properties of 11-Azaprostaglandin Derivatives 148
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 147
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 146
A new, efficient synthesis of muscimol (5-ammoniomethylisoxazol-3-olate). 145
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 145
A facile, efficient synthesis of 2-substituted-4-hydroxy-2-cyclopenten-1-ones 143
Geiparvarin analogs. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates. 142
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 141
A [3 + 2] nitrile oxide cycloaddition approach to retinoids 140
Ethyl 2,4-dioxoalkanoates as starting materials for a convenient route to 3(2H)-furanones and 3(2H)-furanimines 140
Methyl 4-oxothiolane-3-carboxylate and methyl 2-methyl-4-oxothiolane-3- carboxylate anions as synthetic equivalents of α-acrylate and α-crotonate anions. Formal synthesis of integerrinecic acid 139
Geiparvarin Analogs. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain 139
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 138
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 138
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 138
A [3+2] nitrile oxide intermolecular cycloaddition approach to 4,5-dihydro-3(2H)-furanone and 3(2H)-furanone ring systems: application to the formal synthesis of (±)-ascofuranone and geiparvarin. 138
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 138
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 137
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 137
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 136
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 136
3,5-Disubstituted isoxazoles as a latent aldol moiety: application to the synthesis of (±)-[6]-gingerol. 135
Blockade of A2A receptors plus L-DOPA after nigrostriatal lesion results in GAD67 mRNA changes different from L-DOPA alone in the rat globus pallidus and substantia nigra reticulata 135
Adenosine receptors and human melanoma 135
Geiparvarin Analogs. 4.1. Synthesis and Cytostatic Activity of Geiparvarin Analogs Bearing a Carbamate Moiety or a Furocoumarin Fragment on the Alkenyl Side Chain 134
2-Arylamino-4-Amino-5-Aroylthiazoles. "One-Pot" Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization. 134
Current status of A1 adenosine receptor allosteric enhancers 134
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 134
Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors 134
3,5-Disubstituted isoxazoles as synthons for (±)-pyrenophorin and (±)-vermiculine synthesis. 133
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 133
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 133
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 132
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 132
Design, Synthesis, DNA Binding, and Biological Evaluation of Water-Soluble Hybrid Molecules Containing Two Pyrazole Analogues of the Alkylating Cyclopropylpyrroloindole (CPI) Subunit of the Antitumor Agent CC-1065 and Polypyrrole Minor Groove Binders. 132
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 132
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 132
A formal total synthesis (±)-forskolin through [3+2] nitrile oxide cycloaddition chemistry 131
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 130
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 130
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 130
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 130
DNA minor groove binders as potential antitumor and antimicrobial agents 129
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 129
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 129
2,3a,5,6,7,7a-Hexahydro-3H,4H-benzothiophene-3,4-dione and cyclopenta[b]tetrahydrothiophene-3,4-dione enolate anions as synthetic equivalents to cyclohex-2-enone and cyclopent-2-enone C-2-carbanions. 128
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 128
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 128
Synthesis of 2-(5-substituted isoxazol-3-yl)-4-oxo-3-thiazolidinyl alkanoic acids 127
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 126
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 126
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 126
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 125
Allosteric modulators for the A1-adenosine receptor 125
Hybrid molecules based on distamycin A as potential antitumor agents 125
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells. 124
A new nitrile oxide based synthesis of the antitumor agent geiparvarin 123
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 123
Total synthesis of (±)-isoclovene. 122
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 122
Synthesis of syn- and anti-tricyclo[4.1.0.02,4]heptan-5-ones and related compounds. 121
null 121
Synthesis and antitumor activity of novel distamycin derivatives 121
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 121
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 121
null 121
A new direct glycosylation of pyrimidine, pyrazole, imidazole and purine heterocycles via their N-tetrahydropyranyl (THP) derivatives 121
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 120
null 120
Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors 119
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 119
Recent improvements in the development of A2B adenosine receptor agonists. 119
Blockade of globus pallidus adenosine A2A receptors displays antiparkinsonian activity in 6-hydroxydopamine-lesioned rats treated with D 1 or D2 dopamine receptor agonists 119
Synthesis and cytotoxic activity of 6-vinyl- and 6-ethynyluridine and 8-vinyl- and 8-ethynyladenosine 118
Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c]pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists 118
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 118
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 118
null 118
A3 adenosine receptor antagonists: History and future perspectives 118
Pyrazole-Related Nucleosides. Synthesis and Antiviral/Antitumor Activity of Some Substituted Pyrazole and Pyrazolo[4,3-d]-1,2,3-triazin-4-one Nucleosides 116
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 116
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. 116
Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors 116
Allosteric enhancers for A(1) adenosine receptor 115
Involvement of globus pallidus in the antiparkinsonian effects of adenosine A2A receptor antagonists. 115
A new simple synthesis of a-substituted acrylonitriles 115
Synthetic studies towards Forskolin 115
Preparation of 3,4-dihydroxy-1-benzeneethanol: a reinvestigation 114
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 114
Allosteric Modulators of the A1 Adenosine receptor 114
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 114
Totale 13.495
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Categoria #
all - tutte 115.177
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.081
Totale 116.258
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20195.853 0 0 0 0 0 72 872 36 486 965 1.243 2.179
2019/20208.848 1.601 282 278 1.280 575 1.001 704 875 643 1.046 409 154
2020/20216.321 641 592 270 697 298 649 146 728 122 786 837 555
2021/20225.107 159 470 374 291 374 252 208 244 198 362 528 1.647
2022/20235.148 509 249 108 647 884 775 181 478 626 43 461 187
2023/20241.246 257 469 147 93 213 67 0 0 0 0 0 0
Totale 42.565