BARALDI, Pier Giovanni
 Distribuzione geografica
Continente #
NA - Nord America 30.243
EU - Europa 9.385
AS - Asia 6.715
SA - Sud America 69
AF - Africa 44
OC - Oceania 31
Continente sconosciuto - Info sul continente non disponibili 27
Totale 46.514
Nazione #
US - Stati Uniti d'America 30.141
CN - Cina 3.362
DE - Germania 2.769
UA - Ucraina 2.238
TR - Turchia 1.692
SG - Singapore 1.247
GB - Regno Unito 1.004
IT - Italia 953
SE - Svezia 801
FI - Finlandia 587
RU - Federazione Russa 438
FR - Francia 163
VN - Vietnam 117
PL - Polonia 114
BE - Belgio 98
CA - Canada 82
NL - Olanda 64
IN - India 63
CZ - Repubblica Ceca 37
HK - Hong Kong 37
BR - Brasile 34
KR - Corea 32
JP - Giappone 31
ID - Indonesia 30
AU - Australia 24
EU - Europa 24
LT - Lituania 23
MA - Marocco 23
IR - Iran 22
TW - Taiwan 21
MX - Messico 20
CL - Cile 18
IL - Israele 16
ZA - Sudafrica 16
PK - Pakistan 13
RO - Romania 10
AT - Austria 9
CO - Colombia 9
NO - Norvegia 9
CH - Svizzera 8
HU - Ungheria 8
MY - Malesia 8
ES - Italia 7
GR - Grecia 7
IE - Irlanda 7
NZ - Nuova Zelanda 7
MD - Moldavia 6
IQ - Iraq 5
PT - Portogallo 5
AR - Argentina 4
BG - Bulgaria 4
HR - Croazia 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BD - Bangladesh 3
EG - Egitto 3
PS - Palestinian Territory 3
TH - Thailandia 3
DK - Danimarca 2
LU - Lussemburgo 2
NP - Nepal 2
PE - Perù 2
RS - Serbia 2
SI - Slovenia 2
TN - Tunisia 2
AE - Emirati Arabi Uniti 1
EC - Ecuador 1
IM - Isola di Man 1
JO - Giordania 1
KH - Cambogia 1
LK - Sri Lanka 1
MC - Monaco 1
ME - Montenegro 1
MN - Mongolia 1
PH - Filippine 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 46.514
Città #
Woodbridge 3.792
Fairfield 3.594
Jacksonville 2.451
Houston 2.445
Chandler 2.077
Ashburn 2.045
Ann Arbor 1.914
Seattle 1.499
Wilmington 1.382
Santa Clara 1.379
Cambridge 1.093
Singapore 987
Izmir 799
Nanjing 772
Beijing 543
Princeton 512
Boardman 399
San Diego 322
Shenyang 266
Ferrara 265
Nanchang 213
Milan 209
Shanghai 203
Los Angeles 162
Hebei 158
New York 156
San Mateo 154
Bremen 144
Addison 142
Tianjin 141
Changsha 140
Jiaxing 122
Helsinki 117
Dearborn 114
Dong Ket 114
Jinan 106
Warsaw 104
Brussels 97
Philadelphia 88
Falls Church 86
London 86
Norwalk 83
Redwood City 78
Munich 77
Kunming 76
Zhengzhou 70
Mountain View 59
Guangzhou 50
Ningbo 50
Auburn Hills 47
Orange 47
Verona 43
Amsterdam 38
Des Moines 37
Frankfurt am Main 37
Indiana 37
Taizhou 36
Toronto 35
Lanzhou 32
Hong Kong 29
Tappahannock 28
Hangzhou 27
Chicago 26
Paris 26
Jakarta 25
Washington 25
Ottawa 24
Düsseldorf 22
Mcallen 22
Redmond 22
Falkenstein 21
Taipei 21
Augusta 20
Haikou 20
Montréal 20
Brno 19
Duncan 15
Leawood 15
Hefei 14
Kilburn 14
San Francisco 14
Rome 13
Weihai 13
Xian 13
Bari 12
Monmouth Junction 12
Espoo 11
Fuzhou 11
Olomouc 11
Yellow Springs 11
Ardabil 10
Marrakesh 10
Taiyuan 10
Chiswick 9
Corvallis 9
Mumbai 9
Bologna 8
Padova 8
Palo Alto 8
Changchun 7
Totale 32.988
Nome #
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 367
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 342
1,4-Diketones via Isoxazole Intermediates 317
1,2,3-triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: A new class of A(2A) adenosine receptor antagonists 299
null 227
A glance at adenosine receptors: Novel target for antitumor therapy 202
A new, efficient synthesis of muscimol (5-ammoniomethylisoxazol-3-olate). 173
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 171
A facile, efficient synthesis of 2-substituted-4-hydroxy-2-cyclopenten-1-ones 168
The A3 adenosine receptor: history and perspectives 167
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 165
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 161
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 161
Azaprostaglandin Analogues. Synthesis and Biological Properties of 11-Azaprostaglandin Derivatives 160
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 158
A3 adenosine receptor antagonists: History and future perspectives 158
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 157
3,5-Disubstituted isoxazoles as a latent aldol moiety: application to the synthesis of (±)-[6]-gingerol. 156
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 155
A [3+2] nitrile oxide intermolecular cycloaddition approach to 4,5-dihydro-3(2H)-furanone and 3(2H)-furanone ring systems: application to the formal synthesis of (±)-ascofuranone and geiparvarin. 154
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 153
Design, Synthesis, DNA Binding, and Biological Evaluation of Water-Soluble Hybrid Molecules Containing Two Pyrazole Analogues of the Alkylating Cyclopropylpyrroloindole (CPI) Subunit of the Antitumor Agent CC-1065 and Polypyrrole Minor Groove Binders. 152
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 152
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 150
Active γ-manganese dioxide promoted conversion of 4,5-dihydro-1,2-oxazoles to 1,2-oxazoles. 150
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 150
3,5-Disubstituted isoxazoles as synthons for (±)-pyrenophorin and (±)-vermiculine synthesis. 149
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 149
Geiparvarin analogs. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates. 148
DNA minor groove binders as potential antitumor and antimicrobial agents 148
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 148
A formal total synthesis (±)-forskolin through [3+2] nitrile oxide cycloaddition chemistry 148
Methyl 4-oxothiolane-3-carboxylate and methyl 2-methyl-4-oxothiolane-3- carboxylate anions as synthetic equivalents of α-acrylate and α-crotonate anions. Formal synthesis of integerrinecic acid 147
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 147
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 147
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 146
Adenosine receptors and human melanoma 146
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 146
Geiparvarin Analogs. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain 145
Blockade of A2A receptors plus L-DOPA after nigrostriatal lesion results in GAD67 mRNA changes different from L-DOPA alone in the rat globus pallidus and substantia nigra reticulata 145
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 145
Ethyl 2,4-dioxoalkanoates as starting materials for a convenient route to 3(2H)-furanones and 3(2H)-furanimines 144
Current status of A1 adenosine receptor allosteric enhancers 143
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 143
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 143
2,3a,5,6,7,7a-Hexahydro-3H,4H-benzothiophene-3,4-dione and cyclopenta[b]tetrahydrothiophene-3,4-dione enolate anions as synthetic equivalents to cyclohex-2-enone and cyclopent-2-enone C-2-carbanions. 142
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 142
2-Arylamino-4-Amino-5-Aroylthiazoles. "One-Pot" Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization. 142
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 141
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 141
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 141
Hybrid molecules based on distamycin A as potential antitumor agents 141
Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors 141
A [3 + 2] nitrile oxide cycloaddition approach to retinoids 140
Geiparvarin Analogs. 4.1. Synthesis and Cytostatic Activity of Geiparvarin Analogs Bearing a Carbamate Moiety or a Furocoumarin Fragment on the Alkenyl Side Chain 140
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 140
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 139
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 138
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 137
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 137
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 137
Allosteric modulators for the A1-adenosine receptor 137
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 137
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 136
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 135
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 135
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 135
Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors 134
Synthesis of 2-(5-substituted isoxazol-3-yl)-4-oxo-3-thiazolidinyl alkanoic acids 133
A new nitrile oxide based synthesis of the antitumor agent geiparvarin 133
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 133
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 133
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 133
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 132
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells. 131
A new direct glycosylation of pyrimidine, pyrazole, imidazole and purine heterocycles via their N-tetrahydropyranyl (THP) derivatives 131
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 130
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 130
Total synthesis of (±)-isoclovene. 129
Recent improvements in the development of A2B adenosine receptor agonists. 129
A new simple synthesis of a-substituted acrylonitriles 129
Synthesis of syn- and anti-tricyclo[4.1.0.02,4]heptan-5-ones and related compounds. 128
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 128
Synthesis and antitumor activity of novel distamycin derivatives 127
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 127
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 127
Synthesis of 6‐substituted‐4,5‐dihydro‐3(2H)‐pyridazinones 126
Synthesis and cytotoxic activity of 6-vinyl- and 6-ethynyluridine and 8-vinyl- and 8-ethynyladenosine 126
Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c]pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists 126
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 126
Preparation of 3,4-dihydroxy-1-benzeneethanol: a reinvestigation 125
Stereospecific nitromethane conjugate addition to 4-oxygenated 2-substituted cyclopent-2-enones: a simple approach to prostaglandins. 125
Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors 125
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 125
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 124
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 124
Blockade of globus pallidus adenosine A2A receptors displays antiparkinsonian activity in 6-hydroxydopamine-lesioned rats treated with D 1 or D2 dopamine receptor agonists 124
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 124
Pyrazole-Related Nucleosides. Synthesis and Antiviral/Antitumor Activity of Some Substituted Pyrazole and Pyrazolo[4,3-d]-1,2,3-triazin-4-one Nucleosides 123
Allosteric enhancers for A(1) adenosine receptor 123
Totale 14.979
Categoria #
all - tutte 197.392
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.019
Totale 199.411


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20204.832 0 0 0 0 0 1.001 704 875 643 1.046 409 154
2020/20216.321 641 592 270 697 298 649 146 728 122 786 837 555
2021/20225.107 159 470 374 291 374 252 208 244 198 362 528 1.647
2022/20234.812 509 249 108 647 884 775 145 392 614 31 286 172
2023/20242.417 243 309 129 82 170 287 95 398 28 60 56 560
2024/20253.584 292 299 752 335 1.156 750 0 0 0 0 0 0
Totale 46.984