BARALDI, Pier Giovanni
 Distribuzione geografica
Continente #
NA - Nord America 43.147
AS - Asia 21.959
EU - Europa 20.289
SA - Sud America 3.379
AF - Africa 512
OC - Oceania 45
Continente sconosciuto - Info sul continente non disponibili 33
Totale 89.364
Nazione #
US - Stati Uniti d'America 42.304
FI - Finlandia 8.286
SG - Singapore 7.682
CN - Cina 5.901
DE - Germania 3.425
BR - Brasile 2.606
UA - Ucraina 2.333
VN - Vietnam 2.166
HK - Hong Kong 1.935
TR - Turchia 1.836
GB - Regno Unito 1.365
IT - Italia 1.267
RU - Federazione Russa 908
SE - Svezia 872
FR - Francia 808
IN - India 463
JP - Giappone 462
CA - Canada 365
MX - Messico 346
BD - Bangladesh 345
AR - Argentina 275
PL - Polonia 260
ZA - Sudafrica 207
IQ - Iraq 179
NL - Olanda 152
ID - Indonesia 132
ES - Italia 118
CO - Colombia 112
PK - Pakistan 111
BE - Belgio 103
EC - Ecuador 94
MA - Marocco 89
TW - Taiwan 87
SA - Arabia Saudita 80
VE - Venezuela 76
CL - Cile 70
UZ - Uzbekistan 66
MY - Malesia 62
KR - Corea 57
LT - Lituania 57
PH - Filippine 54
PY - Paraguay 53
AE - Emirati Arabi Uniti 49
CZ - Repubblica Ceca 49
EG - Egitto 47
AT - Austria 37
IL - Israele 36
TN - Tunisia 36
AU - Australia 34
KE - Kenya 33
IR - Iran 30
PE - Perù 30
BO - Bolivia 28
CR - Costa Rica 28
JO - Giordania 27
UY - Uruguay 27
NP - Nepal 26
IE - Irlanda 25
EU - Europa 24
TH - Thailandia 21
AZ - Azerbaigian 20
GR - Grecia 20
CH - Svizzera 19
RO - Romania 19
DZ - Algeria 18
ET - Etiopia 18
JM - Giamaica 18
KZ - Kazakistan 17
PS - Palestinian Territory 17
PT - Portogallo 17
AL - Albania 16
HU - Ungheria 14
TT - Trinidad e Tobago 14
BH - Bahrain 13
KG - Kirghizistan 13
LB - Libano 13
OM - Oman 13
PA - Panama 13
BG - Bulgaria 12
MD - Moldavia 12
SK - Slovacchia (Repubblica Slovacca) 12
HN - Honduras 11
SY - Repubblica araba siriana 11
BY - Bielorussia 10
HR - Croazia 10
LV - Lettonia 10
NO - Norvegia 10
NZ - Nuova Zelanda 10
AO - Angola 9
DO - Repubblica Dominicana 9
RS - Serbia 9
SN - Senegal 9
MN - Mongolia 8
NI - Nicaragua 8
CI - Costa d'Avorio 7
GT - Guatemala 7
SV - El Salvador 7
DK - Danimarca 6
MT - Malta 6
MU - Mauritius 6
Totale 89.247
Città #
Helsinki 7.702
Singapore 5.022
Ashburn 4.108
Woodbridge 3.789
Fairfield 3.580
Dallas 2.779
Houston 2.487
Jacksonville 2.453
San Jose 2.442
Chandler 2.073
Ann Arbor 1.911
Hong Kong 1.812
Santa Clara 1.695
Beijing 1.571
Seattle 1.531
Wilmington 1.378
Cambridge 1.093
Izmir 805
Nanjing 776
Ho Chi Minh City 694
Los Angeles 538
Princeton 515
Hanoi 494
New York 474
Tokyo 422
Boardman 405
Lauterbourg 396
Munich 367
Council Bluffs 344
San Diego 323
Ferrara 271
Shenyang 263
São Paulo 249
Milan 245
Shanghai 226
Hefei 220
Nanchang 213
Warsaw 209
Mexico City 201
Tianjin 182
London 179
Orem 158
Hebei 157
Falkenstein 154
San Mateo 153
Changsha 149
Chicago 145
Bremen 144
Addison 141
Brooklyn 122
Jiaxing 121
Frankfurt am Main 115
Dearborn 114
Dong Ket 114
The Dalles 112
Turku 112
Jinan 111
Montreal 106
Philadelphia 102
Chennai 99
Brussels 98
Buffalo 98
Da Nang 95
Toronto 91
Johannesburg 90
Atlanta 89
Amsterdam 88
Baghdad 88
Haiphong 88
Falls Church 86
Moscow 86
Norwalk 84
Rio de Janeiro 84
San Francisco 80
Kunming 79
Redwood City 78
Zhengzhou 76
Denver 75
Guangzhou 72
Phoenix 71
Stockholm 66
Boston 61
Taipei 60
Mountain View 59
Poplar 58
Tashkent 58
Manchester 57
Belo Horizonte 54
Brasília 54
Mumbai 53
Ningbo 51
Jakarta 48
Auburn Hills 47
Orange 47
Hải Dương 46
Verona 45
Des Moines 44
Dhaka 43
Ankara 42
Quito 41
Totale 61.596
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.103
1,4-Diketones via Isoxazole Intermediates 3.077
1,2,3-triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: A new class of A(2A) adenosine receptor antagonists 3.047
Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale Distamicina A 1.969
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 531
The use of phase-transfer catalysis for the N-alkylation of indole. 518
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 333
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 324
A glance at adenosine receptors: Novel target for antitumor therapy 312
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 310
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 303
A new, efficient synthesis of muscimol (5-ammoniomethylisoxazol-3-olate). 302
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 297
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 292
A facile, efficient synthesis of 2-substituted-4-hydroxy-2-cyclopenten-1-ones 290
A3 adenosine receptor antagonists: History and future perspectives 289
The A3 adenosine receptor: history and perspectives 289
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 281
A [3+2] nitrile oxide intermolecular cycloaddition approach to 4,5-dihydro-3(2H)-furanone and 3(2H)-furanone ring systems: application to the formal synthesis of (±)-ascofuranone and geiparvarin. 280
3,5-Disubstituted isoxazoles as a latent aldol moiety: Application to the synthesis of (±)-[6]-gingerol 273
A formal total synthesis (±)-forskolin through [3+2] nitrile oxide cycloaddition chemistry 270
Azaprostaglandin Analogues. Synthesis and Biological Properties of 11-Azaprostaglandin Derivatives 269
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 268
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 267
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 264
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 264
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 263
Adenosine receptors and human melanoma 258
Allosteric modulators for the A1-adenosine receptor 258
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 258
2,3a,5,6,7,7a-Hexahydro-3H,4H-benzothiophene-3,4-dione and cyclopenta[b]tetrahydrothiophene-3,4-dione enolate anions as synthetic equivalents to cyclohex-2-enone and cyclopent-2-enone C-2-carbanions. 257
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 254
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders 254
A [3 + 2] nitrile oxide cycloaddition approach to retinoids 253
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 251
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 251
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 247
A new nitrile oxide based synthesis of the antitumor agent geiparvarin 246
3,5-Disubstituted Isoxazoles as Synthons for (±)-Pyrenophorin and (±)-Vermiculine Synthesis 246
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 246
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 244
DNA minor groove binders as potential antitumor and antimicrobial agents 242
Allosteric enhancers for A(1) adenosine receptor 241
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 241
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 241
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 241
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 240
2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization 239
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 238
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 234
Blockade of A2A receptors plus L-DOPA after nigrostriatal lesion results in GAD67 mRNA changes different from L-DOPA alone in the rat globus pallidus and substantia nigra reticulata 233
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 231
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 230
A new direct glycosylation of pyrimidine, pyrazole, imidazole and purine heterocycles via their N-tetrahydropyranyl (THP) derivatives 230
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 229
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 228
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 228
Active γ-manganese dioxide promoted conversion of 4,5-dihydro-1,2-oxazoles to 1,2-oxazoles. 228
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 228
null 227
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 226
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 226
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 226
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 224
Hybrid molecules between distamycin A and active moieties of antitumor agents 224
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 223
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 223
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 222
Current status of A1 adenosine receptor allosteric enhancers 222
Hybrid molecules based on distamycin A as potential antitumor agents 222
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 221
Carboxyl activation in peptide synthesis using 4-oximino-pyrazol-5-ones 221
Geiparvarin analogs. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates. 219
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 219
A one-pot glycosylation of tetrahydropyranyl (THP) ether intermediates 218
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 218
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 217
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 216
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 216
Methyl 4-oxothiolane-3-carboxylate and methyl 2-methyl-4-oxothiolane-3- carboxylate anions as synthetic equivalents of α-acrylate and α-crotonate anions. Formal synthesis of integerrinecic acid 215
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 215
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 215
[3H]-MRE 2029-F20, a novel selective antagonist radioligand, for the pharmacological and biochemical characterization of A2B receptors. 215
Ethyl 2,4-dioxoalkanoates as starting materials for a convenient route to 3(2H)-furanones and 3(2H)-furanimines 214
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 214
A new simple synthesis of a-substituted acrylonitriles 214
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 212
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 212
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 212
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 211
A new synthetic approach to indazole synthesis 211
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 210
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 210
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 209
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 209
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 209
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 208
[3H]MRE2029F20 a new selective antagonist radioligand for the human A2B adenosine receptors. 208
Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors 208
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 207
Totale 34.898
Categoria #
all - tutte 350.754
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 3.473
Totale 354.227


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20225.094 159 470 372 291 373 250 208 243 197 361 528 1.642
2022/20234.800 508 249 108 646 881 773 145 390 611 31 286 172
2023/20242.411 243 307 129 82 170 287 95 394 28 60 56 560
2024/20259.331 291 294 752 335 1.154 770 273 638 1.285 1.084 1.377 1.078
2025/202636.487 2.653 1.709 4.045 3.576 3.659 1.892 3.275 1.339 9.919 3.179 886 355
2026/2027740 740 0 0 0 0 0 0 0 0 0 0 0
Totale 89.843