Tethering the N-8-substituents of N-8-substituted styryl xanthine to N-7 has resulted in a series of conformationally constrained styryl xanthine analogs having the general formula 8. These new compounds have also been evaluated in order to investigate if the A2A adenosine receptor would be able to tolerate such a modification.
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines
BARALDI, Pier Giovanni;FRUTTAROLO, Francesca;AGHAZADEH TABRIZI, Mojgan;ROMAGNOLI, Romeo
2001
Abstract
Tethering the N-8-substituents of N-8-substituted styryl xanthine to N-7 has resulted in a series of conformationally constrained styryl xanthine analogs having the general formula 8. These new compounds have also been evaluated in order to investigate if the A2A adenosine receptor would be able to tolerate such a modification.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
