1-Alkylindoles were prepd. in 78-98% yields by alkylation of indole with alkyl sulfates, alkyl iodides, or alkyl bromides in a two-phase system of 50% aq. NaOH and C6H6 contg. Bu4N+HSO4-.
The use of phase-transfer catalysis for the N-alkylation of indole.
BARCO, Achille;BENETTI, Simonetta;POLLINI, Gian Piero;BARALDI, Pier Giovanni
1976
Abstract
1-Alkylindoles were prepd. in 78-98% yields by alkylation of indole with alkyl sulfates, alkyl iodides, or alkyl bromides in a two-phase system of 50% aq. NaOH and C6H6 contg. Bu4N+HSO4-.File in questo prodotto:
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