SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

SIMONI, Daniele
 Distribuzione geografica
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Continente #
NA - Nord America 15.208
AS - Asia 7.265
EU - Europa 5.779
SA - Sud America 1.080
AF - Africa 154
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 12
Totale 29.510
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Nazione #
US - Stati Uniti d'America 14.945
SG - Singapore 2.676
FI - Finlandia 2.108
CN - Cina 1.930
BR - Brasile 841
DE - Germania 811
VN - Vietnam 789
UA - Ucraina 719
TR - Turchia 616
HK - Hong Kong 551
IT - Italia 505
GB - Regno Unito 477
SE - Svezia 309
FR - Francia 258
RU - Federazione Russa 193
IN - India 144
CA - Canada 128
JP - Giappone 126
PL - Polonia 113
MX - Messico 105
AR - Argentina 80
BD - Bangladesh 73
NL - Olanda 66
ZA - Sudafrica 62
ES - Italia 50
IQ - Iraq 46
PK - Pakistan 44
BE - Belgio 40
EC - Ecuador 37
ID - Indonesia 35
CL - Cile 31
CO - Colombia 30
MA - Marocco 29
PH - Filippine 29
SA - Arabia Saudita 26
LT - Lituania 24
AE - Emirati Arabi Uniti 22
PY - Paraguay 22
UZ - Uzbekistan 22
CZ - Repubblica Ceca 21
VE - Venezuela 19
MY - Malesia 16
KR - Corea 15
IE - Irlanda 13
JO - Giordania 12
IR - Iran 11
RO - Romania 11
AT - Austria 10
AU - Australia 10
CH - Svizzera 10
EG - Egitto 10
EU - Europa 9
DZ - Algeria 8
IL - Israele 8
TW - Taiwan 8
KE - Kenya 7
TH - Thailandia 7
TN - Tunisia 7
UY - Uruguay 7
AO - Angola 6
AZ - Azerbaigian 6
BH - Bahrain 6
ET - Etiopia 6
OM - Oman 6
PE - Perù 6
RS - Serbia 6
BG - Bulgaria 5
BO - Bolivia 5
JM - Giamaica 5
LB - Libano 5
NO - Norvegia 5
HU - Ungheria 4
KZ - Kazakistan 4
NP - Nepal 4
PA - Panama 4
PT - Portogallo 4
SN - Senegal 4
AL - Albania 3
CI - Costa d'Avorio 3
DO - Repubblica Dominicana 3
GA - Gabon 3
GE - Georgia 3
GT - Guatemala 3
KG - Kirghizistan 3
KH - Cambogia 3
LV - Lettonia 3
NI - Nicaragua 3
SY - Repubblica araba siriana 3
TT - Trinidad e Tobago 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BN - Brunei Darussalam 2
CR - Costa Rica 2
CY - Cipro 2
DM - Dominica 2
EE - Estonia 2
GR - Grecia 2
GY - Guiana 2
KW - Kuwait 2
MM - Myanmar 2
MN - Mongolia 2
Totale 29.480
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Città #
Helsinki 1.924
Singapore 1.772
Ashburn 1.571
Fairfield 1.464
Woodbridge 1.295
Houston 898
Dallas 881
San Jose 783
Jacksonville 774
Chandler 706
Seattle 659
Ann Arbor 631
Santa Clara 565
Beijing 559
Hong Kong 534
Wilmington 522
Cambridge 464
Izmir 249
Ho Chi Minh City 247
New York 246
Nanjing 242
Los Angeles 192
Hanoi 175
Princeton 157
Boardman 147
San Diego 138
Munich 137
Lauterbourg 128
Tokyo 114
Addison 102
The Dalles 99
Warsaw 92
Shanghai 87
São Paulo 87
Shenyang 77
London 74
Nanchang 71
Mexico City 69
Milan 69
Chicago 64
Hefei 63
Tianjin 61
Ferrara 59
Changsha 57
Hebei 57
Dong Ket 54
San Mateo 54
Orem 53
Frankfurt am Main 47
Jinan 42
Bremen 41
Chennai 41
Montreal 41
Haiphong 40
Turku 40
Brussels 39
Amsterdam 35
Brooklyn 35
Da Nang 35
Falkenstein 35
San Francisco 35
Jiaxing 33
Moscow 33
Atlanta 32
Buffalo 32
Falls Church 32
Denver 31
Rio de Janeiro 29
Boston 28
Guangzhou 28
Philadelphia 28
Toronto 27
Johannesburg 25
Phoenix 25
Verona 25
Baghdad 24
Auburn Hills 21
Norwalk 21
Bologna 20
Tashkent 20
Belo Horizonte 19
Mountain View 19
Poplar 19
Stockholm 19
Brasília 18
Council Bluffs 18
Manchester 18
Mumbai 18
Zhengzhou 18
Jakarta 17
Kunming 17
Washington 17
Dearborn 16
Hangzhou 16
Quito 16
Redwood City 16
Biên Hòa 15
Mcallen 15
Rome 15
Salt Lake City 15
Totale 20.884
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Nome #
1,2,4-triazoles. Improved synthesis of 5-substituited 4-amino-3mercato-(4H)-1,2,4 triazoles and a facile route to 3,6-disubstituited 1,24-triazolo[3,4b][1,3,4]thiadiazoles 2.998
1,5,7-Triazabicyclo[4.4.0]dec-1-ene (TBD), 7-methyl-TBD (MTBD) and the polymer-supported TBD (P-TBD): Three efficient catalysts for the nitroaldol (Henry) reaction and for the addition of dialkyl phosphites to unsaturated systems 326
4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors 287
A facile, efficient synthesis of 2-substituted-4-hydroxy-2-cyclopenten-1-ones 286
A [3+2] nitrile oxide intermolecular cycloaddition approach to 4,5-dihydro-3(2H)-furanone and 3(2H)-furanone ring systems: application to the formal synthesis of (±)-ascofuranone and geiparvarin. 277
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 277
A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approach 272
Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitor 268
Retinoic acid conjugates as potential antitumor agents: Synthesis and biological activity of conjugates with Ara-A, Ara-C, 3(2H)-furanone, and aniline mustard moieties 265
3,5-Disubstituted isoxazoles as a latent aldol moiety: Application to the synthesis of (±)-[6]-gingerol 264
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 263
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 262
Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors 253
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 252
A [3 + 2] nitrile oxide cycloaddition approach to retinoids 251
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity 246
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter 243
A new nitrile oxide based synthesis of the antitumor agent geiparvarin 241
Design, synthesis and biological evaluation of novel stilbene-based antitumor agents 241
Novel terphenyls and 3,5-diaryl isoxazole derivatives endowed with growth supporting and antiapoptotic properties 239
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 238
3,5-Disubstituted Isoxazoles as Synthons for (±)-Pyrenophorin and (±)-Vermiculine Synthesis 235
Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer 233
A new direct glycosylation of pyrimidine, pyrazole, imidazole and purine heterocycles via their N-tetrahydropyranyl (THP) derivatives 227
Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growth 224
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 222
Development of water soluble derivatives of cis-3, 4', 5-trimethoxy-3'- aminostilbene for optimization and use in cancer therapy 221
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 220
Geiparvarin analogs. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates. 215
A one-pot glycosylation of tetrahydropyranyl (THP) ether intermediates 214
Ethyl 2,4-dioxoalkanoates as starting materials for a convenient route to 3(2H)-furanones and 3(2H)-furanimines 212
Stilbene 5c, a microtubule poison with vascular disrupting properties that induces multiple modes of growth arrest and cell death 212
Methyl 4-oxothiolane-3-carboxylate and methyl 2-methyl-4-oxothiolane-3- carboxylate anions as synthetic equivalents of α-acrylate and α-crotonate anions. Formal synthesis of integerrinecic acid 210
Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents 209
Studies on the apoptotic activity of natural and synthetic retinoids: Discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells 209
Antitumor effects of curcumin and structurally β-diketone modified analogs on multidrug resistant cancer cells 209
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 208
Synthesis of 8-oxa analogues of norcocaine endowed with interesting cocaine-like activity 207
Novel combretastatin analogues endowed with antitumor activity 204
Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities 203
Preparation of 3,4-dihydroxy-1-benzeneethanol: a reinvestigation 200
Cyclic guanidines: Synthesis of 4,6,7,8‐tetrahydro‐1H‐imidazo[1,2‐a]pyrazolo[3,4‐d]pyrimidin‐7‐ones and 1,4,6,7,8,9‐hexahydropyrazolo[3′,4′:4,5]pyrimido[2,1‐c] [1,2,4]triazin‐7‐ones 200
Geiparvarin Analogs. 4.1. Synthesis and Cytostatic Activity of Geiparvarin Analogs Bearing a Carbamate Moiety or a Furocoumarin Fragment on the Alkenyl Side Chain 199
Geiparvarin Analogs. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain 195
Synthesis and cytotoxic activity of 6-vinyl- and 6-ethynyluridine and 8-vinyl- and 8-ethynyladenosine 194
The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: Analysis of the possible molecular basis 194
Derivati isossazolici come induttori di emoglobina fetale in precursori eritroidi derivati da pazienti beta-talassemici 194
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells. 194
Synthesis of syn- and anti-tricyclo [4.1.0.02,4] heptan-5-ones and related compounds 193
Antitumor effects of new synthetic isoxazole derivatives 190
Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a γδ-T lymphocytes-mediated activation mechanism 188
5-Phenyl-isoxazole-3-carboxamides modulating Hsp90 with antitumoral activities 186
A PLE-based resolution of cocaine, pseudococaine and 6-and 7-methoxylated cocaine analogues 185
A practical entry to C18-constrained-E-ring analogues of methyllycaconitine (MLA): a concise new stereoselective approach to 8-oxa-decahydrolsoquinolines accompanied by a simple microwaves-assisted synthesis of the succinimidobenzoate appendage of MLA 185
Pterostilbene and 3'-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells. 183
Strong Bicyclic Guanidine Base-promoted Wittig and Horner-Wadsworth-Emmons Reactions 183
Synthesis of 2-(5-substituted isoxazol-3-yl)-4-oxo-3-thiazolidinyl alkanoic acids 182
Sintesi di derivati pirazolici e pirazolo[4,3-d]pirimidonici. Nota II 182
Enantioselective deprotonation of the 8-oxabicyclo[3.2.1]octan-3-one: Synthesis of 8-oxa-norcocaines and 8-oxa-pseudonorcocaines 182
3,6-Disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles: synthesis and evaluation for antimicrobial and antiviral activity. III. 181
Concise enantioselective synthesis and attribution of the absolute configuration of two-carbon bridge methoxylated cocaines and pseudococaines 177
Synthesis of 6‐substituted‐4,5‐dihydro‐3(2H)‐pyridazinones 176
Total Synthesis of (±) isoclovene 175
Analoghi eterociclici dell’acido retinoico (eteroretinoidi) come potenziali agenti “anti-aging”. 175
Cis-3, 4′, 5-Trimethoxy-3′-aminostilbene disrupts tumor vascular perfusion without damaging normal organ perfusion 172
Synthesis and reactivity of a stable precursor of 2-cyano-1,3-butadiene 171
Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c]pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists 171
Two-carbon bridge substituted cocaines: Enantioselective synthesis, attribution of the absolute configuration and biological activity of novel 6- and 7-methoxylated cocaines 171
5-Phenyl-isoxazole-3-carboxamides modulating HSP90 with antitumoral activities 171
A novel α-acrylate anion equivalent: A useful synthon for α-substituted acrylic esters 170
Facile synthesis of pyrazoles and pyrroles via thermolysis of tetrazolo[1,5-b]pyridazines, tetrazolo[1,5-a]pyrimidines and tetrazolo[1,5-a]pyridines 170
Synthesis of natural products via isoxazoles 169
Pig liver esterase (PLE)-mediated resolution of N-substituted 4-benzoyloxy-3-carbomethoxypiperidines: a convenient preparation of 4-hydroxy- and 4-benzoyloxy-3-carbomethoxypiperidines in enantiomerically pure form 169
ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis 169
Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells 169
Facile synthesis of 2-nitroalkanols by Tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones 168
Pyrazole-Related Nucleosides. Synthesis and Antiviral/Antitumor Activity of Some Substituted Pyrazole and Pyrazolo[4,3-d]-1,2,3-triazin-4-one Nucleosides 166
Galangin increases the cytotoxic activity of imatinib mesylate in imatinib-sensitive and imatinib-resistant Bcr-Abl expressing leukemia cells 166
Sintesi di derivati pirazolici e pirazolo[4,3-d]pirimidonici. Nota I 166
Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs) 165
Synthesis of 1-phenyl-substituted 3-methyl-1H-pyrazolo[3,4-b]pyrazine-5,6-dicarboxylic acid diethyl esters. 164
Isoxazole-mediated synthesis of geiparvarin and dihydrogeiparvarin 163
Versatile Synthesis of New Cytotoxic Agents Structurally Related to Emiasterlins 163
Synthesis and Prostaglandin-like Activity of 2-(trans-3-Hydroxy-1-octenyl)-3-indolheptanoic Acid 163
Stereoselective synthesis of 8-aza-9,11-ethenoprostaglandin H1 163
New synthetic isoxazole derivatives as potent inducer of fetal hemoglobin (HbF) in beta-thalassemia 162
L’1,2-Dimetil-4-ossimino-3,5-pirazolidindione come attivatore nella sintesi peptidica 161
Regio - and enantioselective bioreduction of ethyl 2,4-dioxoalkanoates and γ-Keto-α-enamino esters with fermenting baker's yeast 160
Aryl and Heterocyclic Derivatives of Combretastatin A-4 Endowed with Anticancer Properties 159
Ethyl 5-substituted-3-isoxazole carboxvyates as starting materials for a convenient route to 3(2H )-furanones and 3(2H )-iminofuranes 157
Brain receptor binding of analogues of gamma-aminobutyric acid (GABA) 157
Facile access to 2'-O-acyl prodrugs of 1-(β-D-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil (BVAraU) via regioselective esterase-catalyzed hydrolysis of 2',3',5'-triesters 156
Synthesis and Antitumor Activity of a New Class of Pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone Analogs of Pyrrolo[1,4][2,1-c]benzodiazepines 155
Synthesis of an 11-Deoxy-8-azaprostaglandin E1 Intermediate 154
Mechanism of cell death induced by cis-3, 4′, 5-trimethoxy-3′-aminostilbene in ovarian cancer 154
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 154
Stilbene-based anticancer agents: Resveratrol analogues active toward HL60 leukemic cells wit a non-specific phase mechanism 152
Synthesis of 5-Hydroxy-2-oxotetrahydropyrroles 152
Pro‑apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro 151
Structure-activity relationship studies of novel heteroretinoids: Induction of apoptosis in the HL-60 cell line by a novel isoxazole-containing heteroretinoid 149
Totale 22.688
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Categoria #
all - tutte 115.543
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 654
Totale 116.197
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021778 0 0 0 0 0 0 0 0 0 280 297 201
2021/20221.798 67 126 127 106 184 86 71 82 84 93 161 611
2022/20231.649 166 107 57 203 301 254 40 157 211 12 82 59
2023/2024877 91 98 64 22 56 194 40 59 15 26 28 184
2024/20253.170 130 78 289 117 412 225 69 196 428 348 532 346
2025/202611.615 989 555 1.308 1.236 1.440 735 1.124 491 2.691 1.046 0 0
Totale 29.691