SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

SIMONI, Daniele
 Distribuzione geografica
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Continente #
NA - Nord America 13.726
AS - Asia 5.722
EU - Europa 3.562
SA - Sud America 887
AF - Africa 84
Continente sconosciuto - Info sul continente non disponibili 11
OC - Oceania 9
Totale 24.001
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Nazione #
US - Stati Uniti d'America 13.515
SG - Singapore 2.209
CN - Cina 1.759
DE - Germania 793
BR - Brasile 740
UA - Ucraina 707
TR - Turchia 590
HK - Hong Kong 474
IT - Italia 468
GB - Regno Unito 441
VN - Vietnam 342
SE - Svezia 307
FI - Finlandia 215
RU - Federazione Russa 185
FR - Francia 108
CA - Canada 106
PL - Polonia 105
MX - Messico 90
IN - India 81
NL - Olanda 57
AR - Argentina 56
JP - Giappone 40
ZA - Sudafrica 40
BE - Belgio 39
ES - Italia 39
BD - Bangladesh 36
ID - Indonesia 31
IQ - Iraq 27
EC - Ecuador 20
CL - Cile 19
CZ - Repubblica Ceca 19
LT - Lituania 19
PK - Pakistan 18
PY - Paraguay 18
MA - Marocco 16
KR - Corea 15
AE - Emirati Arabi Uniti 13
IR - Iran 11
AT - Austria 10
CO - Colombia 10
IE - Irlanda 10
SA - Arabia Saudita 10
EU - Europa 9
JO - Giordania 9
VE - Venezuela 9
AU - Australia 8
RO - Romania 7
TW - Taiwan 7
CH - Svizzera 6
PH - Filippine 6
UY - Uruguay 6
EG - Egitto 5
IL - Israele 5
NO - Norvegia 5
PE - Perù 5
DZ - Algeria 4
HU - Ungheria 4
KE - Kenya 4
LB - Libano 4
MY - Malesia 4
AL - Albania 3
AZ - Azerbaigian 3
BG - Bulgaria 3
BO - Bolivia 3
GA - Gabon 3
KG - Kirghizistan 3
KH - Cambogia 3
NI - Nicaragua 3
OM - Oman 3
PA - Panama 3
TT - Trinidad e Tobago 3
UZ - Uzbekistan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AO - Angola 2
BH - Bahrain 2
BN - Brunei Darussalam 2
DM - Dominica 2
ET - Etiopia 2
GE - Georgia 2
GR - Grecia 2
MN - Mongolia 2
MT - Malta 2
NP - Nepal 2
PT - Portogallo 2
RS - Serbia 2
SN - Senegal 2
TN - Tunisia 2
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BW - Botswana 1
BY - Bielorussia 1
CD - Congo 1
CI - Costa d'Avorio 1
DK - Danimarca 1
EE - Estonia 1
GT - Guatemala 1
GY - Guiana 1
JM - Giamaica 1
KW - Kuwait 1
Totale 23.994
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Città #
Fairfield 1.464
Singapore 1.340
Woodbridge 1.295
Ashburn 1.269
Houston 898
Dallas 872
Jacksonville 774
Chandler 706
Seattle 658
Ann Arbor 631
Beijing 524
Wilmington 521
Santa Clara 520
Hong Kong 470
Cambridge 464
Izmir 248
Nanjing 242
New York 229
Los Angeles 180
Princeton 157
Boardman 146
Munich 137
San Diego 137
Addison 102
Ho Chi Minh City 97
Warsaw 85
Shanghai 81
São Paulo 80
Shenyang 76
Nanchang 71
The Dalles 66
Mexico City 65
London 64
Milan 64
Hefei 63
Chicago 62
Hanoi 62
Tianjin 60
Ferrara 58
Hebei 57
Changsha 56
Dong Ket 54
San Mateo 54
Jinan 42
Bremen 41
Turku 40
Brussels 39
Frankfurt am Main 36
Falkenstein 35
Montreal 35
Brooklyn 33
Chennai 33
Jiaxing 33
Falls Church 32
San Francisco 32
Tokyo 32
Amsterdam 31
Helsinki 31
Moscow 31
Denver 30
Orem 29
Buffalo 28
Philadelphia 27
Boston 26
Atlanta 24
Verona 24
Guangzhou 23
Phoenix 23
Rio de Janeiro 23
Auburn Hills 21
Norwalk 21
Toronto 21
Bologna 20
Mountain View 19
Belo Horizonte 18
Poplar 18
Brasília 17
Jakarta 17
Kunming 17
Stockholm 17
Washington 17
Zhengzhou 17
Dearborn 16
Redwood City 16
San Jose 16
Hangzhou 15
Mcallen 15
Salt Lake City 15
Taizhou 15
Da Nang 14
Haiphong 14
Johannesburg 14
Rome 14
Des Moines 13
Ankara 12
Baghdad 12
Charlotte 12
Manchester 12
Montréal 12
Augusta 11
Totale 16.560
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Nome #
1,2,4-triazoles. Improved synthesis of 5-substituited 4-amino-3mercato-(4H)-1,2,4 triazoles and a facile route to 3,6-disubstituited 1,24-triazolo[3,4b][1,3,4]thiadiazoles 1.098
1,5,7-Triazabicyclo[4.4.0]dec-1-ene (TBD), 7-methyl-TBD (MTBD) and the polymer-supported TBD (P-TBD): Three efficient catalysts for the nitroaldol (Henry) reaction and for the addition of dialkyl phosphites to unsaturated systems 291
A facile, efficient synthesis of 2-substituted-4-hydroxy-2-cyclopenten-1-ones 252
4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors 246
A [3+2] nitrile oxide intermolecular cycloaddition approach to 4,5-dihydro-3(2H)-furanone and 3(2H)-furanone ring systems: application to the formal synthesis of (±)-ascofuranone and geiparvarin. 239
3,5-Disubstituted isoxazoles as a latent aldol moiety: Application to the synthesis of (±)-[6]-gingerol 238
Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitor 232
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 232
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 228
Retinoic acid conjugates as potential antitumor agents: Synthesis and biological activity of conjugates with Ara-A, Ara-C, 3(2H)-furanone, and aniline mustard moieties 226
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 226
A [3 + 2] nitrile oxide cycloaddition approach to retinoids 222
A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approach 222
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity 220
Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors 217
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 217
A new nitrile oxide based synthesis of the antitumor agent geiparvarin 210
Novel terphenyls and 3,5-diaryl isoxazole derivatives endowed with growth supporting and antiapoptotic properties 206
3,5-Disubstituted Isoxazoles as Synthons for (±)-Pyrenophorin and (±)-Vermiculine Synthesis 205
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter 205
Design, synthesis and biological evaluation of novel stilbene-based antitumor agents 205
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 199
Development of water soluble derivatives of cis-3, 4', 5-trimethoxy-3'- aminostilbene for optimization and use in cancer therapy 199
Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer 199
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 198
A new direct glycosylation of pyrimidine, pyrazole, imidazole and purine heterocycles via their N-tetrahydropyranyl (THP) derivatives 198
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 195
Ethyl 2,4-dioxoalkanoates as starting materials for a convenient route to 3(2H)-furanones and 3(2H)-furanimines 193
Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growth 193
Geiparvarin analogs. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates. 191
Stilbene 5c, a microtubule poison with vascular disrupting properties that induces multiple modes of growth arrest and cell death 191
A one-pot glycosylation of tetrahydropyranyl (THP) ether intermediates 190
Methyl 4-oxothiolane-3-carboxylate and methyl 2-methyl-4-oxothiolane-3- carboxylate anions as synthetic equivalents of α-acrylate and α-crotonate anions. Formal synthesis of integerrinecic acid 185
Geiparvarin Analogs. 4.1. Synthesis and Cytostatic Activity of Geiparvarin Analogs Bearing a Carbamate Moiety or a Furocoumarin Fragment on the Alkenyl Side Chain 183
Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities 182
Cyclic guanidines: Synthesis of 4,6,7,8‐tetrahydro‐1H‐imidazo[1,2‐a]pyrazolo[3,4‐d]pyrimidin‐7‐ones and 1,4,6,7,8,9‐hexahydropyrazolo[3′,4′:4,5]pyrimido[2,1‐c] [1,2,4]triazin‐7‐ones 181
Synthesis of 8-oxa analogues of norcocaine endowed with interesting cocaine-like activity 181
Geiparvarin Analogs. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain 179
Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents 179
Studies on the apoptotic activity of natural and synthetic retinoids: Discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells 179
Preparation of 3,4-dihydroxy-1-benzeneethanol: a reinvestigation 177
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 177
Antitumor effects of curcumin and structurally β-diketone modified analogs on multidrug resistant cancer cells 175
Novel combretastatin analogues endowed with antitumor activity 173
The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: Analysis of the possible molecular basis 171
Synthesis and cytotoxic activity of 6-vinyl- and 6-ethynyluridine and 8-vinyl- and 8-ethynyladenosine 169
Synthesis of syn- and anti-tricyclo [4.1.0.02,4] heptan-5-ones and related compounds 169
Synthesis of 2-(5-substituted isoxazol-3-yl)-4-oxo-3-thiazolidinyl alkanoic acids 166
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells. 165
Total Synthesis of (±) isoclovene 164
Concise enantioselective synthesis and attribution of the absolute configuration of two-carbon bridge methoxylated cocaines and pseudococaines 162
Sintesi di derivati pirazolici e pirazolo[4,3-d]pirimidonici. Nota II 161
Antitumor effects of new synthetic isoxazole derivatives 160
Derivati isossazolici come induttori di emoglobina fetale in precursori eritroidi derivati da pazienti beta-talassemici 160
Synthesis of 6‐substituted‐4,5‐dihydro‐3(2H)‐pyridazinones 159
Enantioselective deprotonation of the 8-oxabicyclo[3.2.1]octan-3-one: Synthesis of 8-oxa-norcocaines and 8-oxa-pseudonorcocaines 158
A PLE-based resolution of cocaine, pseudococaine and 6-and 7-methoxylated cocaine analogues 158
Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a γδ-T lymphocytes-mediated activation mechanism 157
Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c]pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists 156
Synthesis of natural products via isoxazoles 155
Strong Bicyclic Guanidine Base-promoted Wittig and Horner-Wadsworth-Emmons Reactions 155
Pterostilbene and 3'-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells. 154
3,6-Disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles: synthesis and evaluation for antimicrobial and antiviral activity. III. 152
5-Phenyl-isoxazole-3-carboxamides modulating Hsp90 with antitumoral activities 151
Sintesi di derivati pirazolici e pirazolo[4,3-d]pirimidonici. Nota I 150
ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis 149
Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells 149
Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs) 149
Cis-3, 4′, 5-Trimethoxy-3′-aminostilbene disrupts tumor vascular perfusion without damaging normal organ perfusion 148
Facile synthesis of pyrazoles and pyrroles via thermolysis of tetrazolo[1,5-b]pyridazines, tetrazolo[1,5-a]pyrimidines and tetrazolo[1,5-a]pyridines 148
A novel α-acrylate anion equivalent: A useful synthon for α-substituted acrylic esters 147
Synthesis and reactivity of a stable precursor of 2-cyano-1,3-butadiene 147
Pyrazole-Related Nucleosides. Synthesis and Antiviral/Antitumor Activity of Some Substituted Pyrazole and Pyrazolo[4,3-d]-1,2,3-triazin-4-one Nucleosides 147
Galangin increases the cytotoxic activity of imatinib mesylate in imatinib-sensitive and imatinib-resistant Bcr-Abl expressing leukemia cells 147
Facile synthesis of 2-nitroalkanols by Tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones 146
Analoghi eterociclici dell’acido retinoico (eteroretinoidi) come potenziali agenti “anti-aging”. 146
Synthesis of 1-phenyl-substituted 3-methyl-1H-pyrazolo[3,4-b]pyrazine-5,6-dicarboxylic acid diethyl esters. 146
A practical entry to C18-constrained-E-ring analogues of methyllycaconitine (MLA): a concise new stereoselective approach to 8-oxa-decahydrolsoquinolines accompanied by a simple microwaves-assisted synthesis of the succinimidobenzoate appendage of MLA 146
Isoxazole-mediated synthesis of geiparvarin and dihydrogeiparvarin 144
Two-carbon bridge substituted cocaines: Enantioselective synthesis, attribution of the absolute configuration and biological activity of novel 6- and 7-methoxylated cocaines 144
Facile access to 2'-O-acyl prodrugs of 1-(β-D-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil (BVAraU) via regioselective esterase-catalyzed hydrolysis of 2',3',5'-triesters 143
Stereoselective synthesis of 8-aza-9,11-ethenoprostaglandin H1 142
Ethyl 5-substituted-3-isoxazole carboxvyates as starting materials for a convenient route to 3(2H )-furanones and 3(2H )-iminofuranes 141
Mechanism of cell death induced by cis-3, 4′, 5-trimethoxy-3′-aminostilbene in ovarian cancer 141
Synthesis and Prostaglandin-like Activity of 2-(trans-3-Hydroxy-1-octenyl)-3-indolheptanoic Acid 140
Synthesis of an 11-Deoxy-8-azaprostaglandin E1 Intermediate 138
Regio - and enantioselective bioreduction of ethyl 2,4-dioxoalkanoates and γ-Keto-α-enamino esters with fermenting baker's yeast 137
Synthesis of 5-Hydroxy-2-oxotetrahydropyrroles 136
L’1,2-Dimetil-4-ossimino-3,5-pirazolidindione come attivatore nella sintesi peptidica 136
Synthesis and Antitumor Activity of a New Class of Pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone Analogs of Pyrrolo[1,4][2,1-c]benzodiazepines 135
Brain receptor binding of analogues of gamma-aminobutyric acid (GABA) 133
Aryl and Heterocyclic Derivatives of Combretastatin A-4 Endowed with Anticancer Properties 133
Pig liver esterase (PLE)-mediated resolution of N-substituted 4-benzoyloxy-3-carbomethoxypiperidines: a convenient preparation of 4-hydroxy- and 4-benzoyloxy-3-carbomethoxypiperidines in enantiomerically pure form 133
5-Phenyl-isoxazole-3-carboxamides modulating HSP90 with antitumoral activities 133
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 133
Design, synthesis and antiproliferative activity of methyl 4-iodo-1-b-D-ribofuranosyl-pyrazole-3-carboxylate and related compounds 132
New synthetic isoxazole derivatives as potent inducer of fetal hemoglobin (HbF) in beta-thalassemia 131
Structure-activity relationship studies of novel heteroretinoids: Induction of apoptosis in the HL-60 cell line by a novel isoxazole-containing heteroretinoid 130
Stilbene-based anticancer agents: Resveratrol analogues active toward HL60 leukemic cells wit a non-specific phase mechanism 130
Synthesis of 3-Methyl-6-phenylamino-substituted-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-ones 130
Totale 18.196
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Categoria #
all - tutte 106.796
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 609
Totale 107.405
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.371 0 0 0 0 0 233 65 246 49 280 297 201
2021/20221.798 67 126 127 106 184 86 71 82 84 93 161 611
2022/20231.649 166 107 57 203 301 254 40 157 211 12 82 59
2023/2024877 91 98 64 22 56 194 40 59 15 26 28 184
2024/20253.170 130 78 289 117 412 225 69 196 428 348 532 346
2025/20266.106 989 555 1.308 1.236 1.440 578 0 0 0 0 0 0
Totale 24.182