A Mannich-type intramolecular cyclization afforded access to a 8-oxa-decahydroisoquinoline heterocyclic system. Good stereoselectivity was observed. A promising microwave-assisted synthesis of the methylsuccinimidobenzoate moiety of methyllycaconitine has also been carried out.

A practical entry to C18-constrained-E-ring analogues of methyllycaconitine (MLA): a concise new stereoselective approach to 8-oxa-decahydrolsoquinolines accompanied by a simple microwaves-assisted synthesis of the succinimidobenzoate appendage of MLA

SIMONI, Daniele;ROSSI, Marcello;RONDANIN, Riccardo;BARUCHELLO, Riccardo;GRISOLIA, Giuseppina;ELEOPRA, Marco;
2005

Abstract

A Mannich-type intramolecular cyclization afforded access to a 8-oxa-decahydroisoquinoline heterocyclic system. Good stereoselectivity was observed. A promising microwave-assisted synthesis of the methylsuccinimidobenzoate moiety of methyllycaconitine has also been carried out.
2005
Simoni, Daniele; Rossi, Marcello; Rondanin, Riccardo; Baruchello, Riccardo; Grisolia, Giuseppina; Eleopra, Marco; Giovannini, R; Bozzoli, A; Davalli, ...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1208193
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