In recent years considerable chemical and medicinal interest has been focused on prostaglandin analogues in which carbon atoms are replaced by heteroatoms.' Among the azaprostaglandin analogues, which contain one or more nitrogens at almost ever) position of the cyclopentane nucleus, the 1 l-deoxy-8-azai)rostaglandin El (1) is of special interest because of the atti active biological activities.
Synthesis of an 11-Deoxy-8-azaprostaglandin E1 Intermediate
BARCO, Achille;BENETTI, Simonetta;POLLINI, Gian Piero;BARALDI, Pier Giovanni;SIMONI, Daniele;VICENTINI, Chiara Beatrice
1979
Abstract
In recent years considerable chemical and medicinal interest has been focused on prostaglandin analogues in which carbon atoms are replaced by heteroatoms.' Among the azaprostaglandin analogues, which contain one or more nitrogens at almost ever) position of the cyclopentane nucleus, the 1 l-deoxy-8-azai)rostaglandin El (1) is of special interest because of the atti active biological activities.File in questo prodotto:
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