TRAPELLA, Claudio
 Distribuzione geografica
Continente #
NA - Nord America 9.659
EU - Europa 2.791
AS - Asia 1.350
SA - Sud America 24
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 4
AF - Africa 1
Totale 13.835
Nazione #
US - Stati Uniti d'America 9.627
CN - Cina 850
IT - Italia 822
UA - Ucraina 474
DE - Germania 401
GB - Regno Unito 341
TR - Turchia 319
PL - Polonia 235
SE - Svezia 219
FI - Finlandia 121
VN - Vietnam 111
BE - Belgio 81
FR - Francia 33
CA - Canada 29
RU - Federazione Russa 22
IR - Iran 15
IN - India 14
HK - Hong Kong 12
BR - Brasile 9
ES - Italia 9
JP - Giappone 9
CO - Colombia 7
AU - Australia 6
BG - Bulgaria 6
NL - Olanda 6
CL - Cile 4
EU - Europa 4
IE - Irlanda 4
KR - Corea 4
AR - Argentina 3
AT - Austria 3
PT - Portogallo 3
RO - Romania 3
TH - Thailandia 3
CR - Costa Rica 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
NP - Nepal 2
SG - Singapore 2
AE - Emirati Arabi Uniti 1
GR - Grecia 1
HU - Ungheria 1
ID - Indonesia 1
IQ - Iraq 1
KG - Kirghizistan 1
KW - Kuwait 1
LU - Lussemburgo 1
MA - Marocco 1
MY - Malesia 1
PA - Panama 1
PH - Filippine 1
PK - Pakistan 1
SI - Slovenia 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 13.835
Città #
Fairfield 1.351
Woodbridge 1.219
Ann Arbor 801
Houston 766
Ashburn 752
Chandler 672
Seattle 573
Jacksonville 553
Wilmington 523
Cambridge 468
Ferrara 332
Beijing 235
Warsaw 235
Izmir 198
Nanjing 171
Princeton 154
Milan 110
Dong Ket 106
Shanghai 105
New York 101
San Diego 101
Boardman 84
Brussels 77
Dearborn 60
Nanchang 50
Shenyang 50
Addison 46
Bremen 43
Munich 37
Falls Church 36
Redwood City 35
Hebei 32
Jiaxing 32
Tianjin 32
Auburn Hills 31
Bologna 29
London 26
Mcallen 26
Mountain View 25
Norwalk 25
Changsha 24
San Mateo 24
Washington 21
Helsinki 20
Montréal 20
Los Angeles 18
Ferrara di Monte Baldo 17
Zhengzhou 17
Jinan 16
Des Moines 15
Philadelphia 15
Tappahannock 14
Kunming 13
Leawood 12
Ningbo 10
Hong Kong 8
Indiana 8
Orange 8
Redmond 8
Augusta 7
Imola 7
Lanzhou 7
Medellín 7
Rome 7
Taizhou 7
Ardabil 6
Chicago 6
Fossò 6
Hangzhou 6
Hefei 6
Islington 6
Napoli 6
Padova 6
Tokyo 6
Chiswick 5
Guangzhou 5
Haikou 5
San Francisco 5
San Jose 5
Tyler 5
Andover 4
Boulder 4
Brescia 4
Castenaso 4
Catania 4
Changchun 4
Dublin 4
Fuzhou 4
La Canada Flintridge 4
Modena 4
New Bedfont 4
West Jordan 4
Acton 3
Bastia umbra 3
Bentivoglio 3
Bournemouth 3
Brighton 3
Buenos Aires 3
Dallas 3
Frankfurt am Main 3
Totale 10.788
Nome #
1,4-Dithiane-2,5-diol: An Attractive Platform for the Synthesis of Sulfur-Containing Functionalized Heterocycles 233
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 218
null 214
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence 178
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice 177
Design and synthesis of99mTcN-labeled dextran-mannose derivatives for sentinel lymph node detection 173
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 159
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 159
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 156
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ. 153
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 151
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 149
Physicochemical stability of cabazitaxel and docetaxel solutions 146
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor 144
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide. 142
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 140
1‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice 137
Letter to the Editor: Antimicrobial properties of mucus from the brown garden snail Helix aspersa 136
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 136
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 134
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2 133
C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors 131
Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity 131
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 130
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2 128
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor 128
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. 127
Studies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors 126
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 125
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 124
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway 123
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 123
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist 121
Synthesis and biological activity of human neuropeptide S analogues modified in position 2 120
Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors 119
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 118
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor 117
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 117
Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic G i/o protein linked pathways 115
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11) 114
A new synthetic approach to 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-benzimidazol-2-one (J-113397), the first non-peptide ORL-1 receptor antagonist 114
Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains 114
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 114
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: Pharmacological and genetic evidences 112
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores 112
Dopamine-nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity 112
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24. 111
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors 110
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists. 110
null 110
Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine-lactone induces HLA-G expression in human immune cells 109
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice 109
Role of benzimidazole (Bid) in the d-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH2-Bid (UFP-502) 108
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor. 107
null 107
JWH-018 impairs sensorimotor functions in mice 106
Synthesis and proteasome inhibition of N-allyl vinyl ester-based peptides 106
In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1 105
Structure-activity study at positions 3 and 4 of human neuropeptide S. 105
null 105
Recent advances in the stereoselective synthesis of trans-3,4- disubstituted-piperidines: applications to (-)paroxetine 103
Neuropeptide S receptor ligands: a patent review (2005-2016) 102
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist 101
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands 100
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120 100
A Convenient Route to Enantiomerically Pure 2-Substituted Methyl Glycerate Derivatives 100
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis 100
Synthesis and activity of isoxazoline vinyl ester pseudopeptides as proteasome inhibitors. 99
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT 99
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 99
Proteomic approach to the identification of early phase biomarker for anticancer peptides targeting thefolate pathway 98
Synthesis and biological properties of C-terminal vinyl ketone pseudotripeptides 97
null 96
null 96
Sviluppo di un Sistema combinato a filiera controllata per l’allevamento, l’estrazione, la caratterizzazione e la sanificazione del secreto di chiocciola 96
Neuropeptide S inhibits release of 5-HT and glycine in mouse amygdala and frontal/prefrontal cortex through activation of the neuropeptide S receptor. 95
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists. 95
null 94
Mastering chiral substituted 2-oxopiperazines 94
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 94
Modulation of Silent and Constitutively Active Nociceptin/Orphanin FQ Receptors by Potent Receptor Antagonists and Na+ Ions in Rat Sympathetic Neurons. 94
null 94
Triazine Compounds as Antagonists at Bv8-Prokineticin Receptors 93
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl] methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vitro studies 93
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore 92
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with C alpha,alpha-dialkylated amino acids 91
null 88
Helix aspersa muller mucus (Helixcomplex ®) interferes with Herpes simplex 1 virus infection 88
null 87
null 87
Influence of the Side Chain Next to C-Terminal Benzimidazole in Opioid Pseudopeptides Containing the Dmt-Tic Pharmacophore 86
A linear allergic contact dermatitis to p-tert-butylphenol formaldehyde resin sectorially present in a neoprene orthopedic brace: role of spectroscopy 83
NOP receptor pharmacological profile – A dynamic mass redistribution study 83
Anxiolytic and antidepressant-like activities of UFP-512, a novel selective delta opiold receptor agonist 82
Novel halogenated synthetic cannabinoids impair sensorimotor functions in mice 82
Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Galpha(qi5). 81
null 80
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 80
Antinociceptive action of NOP and opioid receptor agonists in the mouse orofacial formalin test 79
The IART approach: new Re-188 nitrido biotinilated radiopharmaceuticals useful for cancer therapy 78
Totale 11.570
Categoria #
all - tutte 51.617
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 218
Totale 51.835


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.437 0 0 0 0 0 0 0 0 0 329 458 650
2019/20203.224 456 115 131 428 246 381 320 319 280 277 181 90
2020/20212.551 151 196 124 232 131 204 169 304 116 400 284 240
2021/20221.780 107 169 150 104 138 68 123 99 75 134 165 448
2022/20231.779 180 156 70 207 254 202 110 158 227 18 111 86
2023/2024895 90 121 90 37 92 227 74 109 38 17 0 0
Totale 14.160