| Nome |
# |
|
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence, file e309ade3-ff1a-3969-e053-3a05fe0a2c94
|
168
|
|
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity, file e309ade4-cfe7-3969-e053-3a05fe0a2c94
|
147
|
|
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT, file e309ade3-f472-3969-e053-3a05fe0a2c94
|
143
|
|
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies, file e309ade3-ff1b-3969-e053-3a05fe0a2c94
|
126
|
|
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction, file e309ade3-fc29-3969-e053-3a05fe0a2c94
|
107
|
|
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts, file e309ade2-10ab-3969-e053-3a05fe0a2c94
|
91
|
|
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2, file e309ade0-a21b-3969-e053-3a05fe0a2c94
|
87
|
|
Sometimes, the Least Demanding Solution Is the Most Suitable: A Careful Survey of NMR Spectra of a Phosphonium Salt Accounted for Its “Unusual Wittig Reaction”, file e309ade2-1f63-3969-e053-3a05fe0a2c94
|
81
|
|
Glyceric Prodrug of Ursodeoxycholic Acid (UDCA): Novozym 435-Catalyzed Synthesis of UDCA-Monoglyceride, file e309ade4-ecdf-3969-e053-3a05fe0a2c94
|
68
|
|
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors, file e309ade3-aff3-3969-e053-3a05fe0a2c94
|
66
|
|
Neuropeptide S receptor ligands: a patent review (2005-2016), file e309ade3-a082-3969-e053-3a05fe0a2c94
|
65
|
|
Design and synthesis of99mTcN-labeled dextran-mannose derivatives for sentinel lymph node detection, file e309ade1-eedf-3969-e053-3a05fe0a2c94
|
64
|
|
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice, file e309ade3-b5f2-3969-e053-3a05fe0a2c94
|
64
|
|
Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine-lactone induces HLA-G expression in human immune cells, file e309ade0-9db4-3969-e053-3a05fe0a2c94
|
62
|
|
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism, file e309ade1-5a00-3969-e053-3a05fe0a2c94
|
62
|
|
Novel Mixed NOP/Opioid Receptor Peptide Agonists, file e309ade4-c82b-3969-e053-3a05fe0a2c94
|
62
|
|
NOP receptor pharmacological profile – A dynamic mass redistribution study, file e309ade2-0201-3969-e053-3a05fe0a2c94
|
60
|
|
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands, file e309ade3-dd14-3969-e053-3a05fe0a2c94
|
53
|
|
Studies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors, file e309ade3-9d3e-3969-e053-3a05fe0a2c94
|
51
|
|
Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains, file e309ade2-30cd-3969-e053-3a05fe0a2c94
|
50
|
|
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting, file e309ade3-ad67-3969-e053-3a05fe0a2c94
|
49
|
|
Bile Acid Binding Protein Functionalization Leads to a Fully Synthetic Rhodopsin Mimic, file e309ade3-c769-3969-e053-3a05fe0a2c94
|
48
|
|
Design of Nanosystems for the Delivery of Quorum Sensing Inhibitors: A Preliminary Study, file e309ade3-295b-3969-e053-3a05fe0a2c94
|
47
|
|
Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis, file e309ade2-aa02-3969-e053-3a05fe0a2c94
|
46
|
|
1,4-Dithiane-2,5-diol: An Attractive Platform for the Synthesis of Sulfur-Containing Functionalized Heterocycles, file e309ade3-8e33-3969-e053-3a05fe0a2c94
|
45
|
|
HelixComplex snail mucus as a potential technology against O3 induced skin damage, file e309ade2-a4f6-3969-e053-3a05fe0a2c94
|
42
|
|
The Fascinating Chemistry of α-Haloamides, file e309ade3-3b87-3969-e053-3a05fe0a2c94
|
42
|
|
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity, file e309ade3-b28b-3969-e053-3a05fe0a2c94
|
41
|
|
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice, file e309ade3-fb5f-3969-e053-3a05fe0a2c94
|
41
|
|
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3, file e309ade3-f612-3969-e053-3a05fe0a2c94
|
39
|
|
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice, file e309ade3-fa8b-3969-e053-3a05fe0a2c94
|
34
|
|
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic., file e309ade0-ab96-3969-e053-3a05fe0a2c94
|
23
|
|
1‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice, file e309ade4-a91e-3969-e053-3a05fe0a2c94
|
22
|
|
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening, file e309ade2-d995-3969-e053-3a05fe0a2c94
|
16
|
|
Enzymatic esterification as potential strategy to enhance the sorbic acid behavior as food and beverage preservative, file e309ade3-2883-3969-e053-3a05fe0a2c94
|
12
|
|
Design of liposomes carrying HelixComplex Snail Mucus: preliminary studies, file e309ade4-cd6c-3969-e053-3a05fe0a2c94
|
10
|
|
Synthesis and NLRP3-Inflammasome Inhibitory Activity of the Naturally Occurring Velutone F and of Its Non-Natural Regioisomeric Chalconoids, file 5fca6ff5-5f02-4b5f-8c70-14bc0a95e879
|
9
|
|
An alternative enzymatic route to the ergogenic ketone body ester (R)-3-hydroxybutyl (r)-3-hydroxybutyrate, file e309ade4-0311-3969-e053-3a05fe0a2c94
|
9
|
|
Glicopro, novel standardized and sterile snail mucus extract for multi-modulative ocular formulations: New perspective in dry eye disease management, file e309ade4-f09b-3969-e053-3a05fe0a2c94
|
9
|
|
A Cationic Contrast Agent in X-ray Imaging of Articular Cartilage: Pre-Clinical Evaluation of Diffusion and Attenuation Properties, file 280b38a0-1259-4868-9ba3-93e5044b2c0b
|
8
|
|
Metabolic profile of the synthetic drug 4,4′-dimethylaminorex in urine by LC–MS-based techniques: selection of the most suitable markers of its intake, file e309ade2-b03d-3969-e053-3a05fe0a2c94
|
8
|
|
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor, file e309ade3-daf9-3969-e053-3a05fe0a2c94
|
8
|
|
Helix aspersa muller mucus (Helixcomplex ®) p41 protein prevents Pseudomonas aeruginosa growth and promotes mammalian bronchial epithelial cell proliferation, file e309ade4-dd15-3969-e053-3a05fe0a2c94
|
8
|
|
Chemoenzymatic Stereodivergent Synthesis of All the Possible Stereoisomers of the 2,3-Dimethylglyceric Acid Ethyl Ester, file e309ade4-e161-3969-e053-3a05fe0a2c94
|
8
|
|
Helix aspersa muller mucus (Helixcomplex ®) interferes with Herpes simplex 1 virus infection, file e309ade5-41b0-3969-e053-3a05fe0a2c94
|
8
|
|
Worsening of the toxic effects of (±)cis-4,4′-dmar following its co-administration with (±)trans-4,4′-dmar: Neuro-behavioural, physiological, immunohistochemical and metabolic studies in mice, file e309ade5-300b-3969-e053-3a05fe0a2c94
|
7
|
|
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis, file e309ade0-405c-3969-e053-3a05fe0a2c94
|
6
|
|
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity, file e309ade0-f547-3969-e053-3a05fe0a2c94
|
6
|
|
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3, file e309ade1-775e-3969-e053-3a05fe0a2c94
|
6
|
|
Functional Profile of Systemic and Intrathecal Cebranopadol in Nonhuman Primates, file e309ade5-3b6a-3969-e053-3a05fe0a2c94
|
6
|
|
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice, file e309ade0-20c3-3969-e053-3a05fe0a2c94
|
5
|
|
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24., file e309ade0-2a4a-3969-e053-3a05fe0a2c94
|
5
|
|
A linear allergic contact dermatitis to p-tert-butylphenol formaldehyde resin sectorially present in a neoprene orthopedic brace: role of spectroscopy, file e309ade0-4857-3969-e053-3a05fe0a2c94
|
5
|
|
1‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice, file e309ade1-3f22-3969-e053-3a05fe0a2c94
|
5
|
|
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction, file e309ade1-f663-3969-e053-3a05fe0a2c94
|
5
|
|
Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68., file e309ade2-090f-3969-e053-3a05fe0a2c94
|
5
|
|
Metabolic profile of the synthetic drug 4,4′-dimethylaminorex in urine by LC–MS-based techniques: selection of the most suitable markers of its intake, file c4ca82a8-850d-4eb6-b63d-f808260e45f2
|
4
|
|
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor, file e309ade0-22de-3969-e053-3a05fe0a2c94
|
4
|
|
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5, file e309ade0-b114-3969-e053-3a05fe0a2c94
|
4
|
|
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies, file e309ade1-1902-3969-e053-3a05fe0a2c94
|
4
|
|
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice, file e309ade1-e52d-3969-e053-3a05fe0a2c94
|
4
|
|
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor, file e309ade3-8d0d-3969-e053-3a05fe0a2c94
|
4
|
|
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence, file e309ade3-b6ad-3969-e053-3a05fe0a2c94
|
4
|
|
Dihydroartemisinin-Ursodeoxycholic Bile Acid Hybrids in the Fight against SARS-CoV-2, file 1062ad79-f1c1-478f-9249-f617ddf96a25
|
3
|
|
Xylitol as a Hydrophilization Moiety for a Biocatalytically Synthesized Ibuprofen Prodrug, file 6a8ed426-e897-493f-90af-77bde31e83b8
|
3
|
|
Dopamine-nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity, file e309ade0-341d-3969-e053-3a05fe0a2c94
|
3
|
|
In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1, file e309ade0-4314-3969-e053-3a05fe0a2c94
|
3
|
|
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence, file e309ade0-daa9-3969-e053-3a05fe0a2c94
|
3
|
|
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice, file e309ade1-a822-3969-e053-3a05fe0a2c94
|
3
|
|
A new amido-phosphine of dichloroacetic acid as an active ligand for metals of pharmaceutical interest. Synthesis, characterization and tests of antiproliferative and pro-apoptotic activity, file e309ade3-1819-3969-e053-3a05fe0a2c94
|
3
|
|
Synthesis and biological evaluation of novel rhodanine-based structures with antiviral activity towards HHV-6 virus, file e309ade5-1987-3969-e053-3a05fe0a2c94
|
3
|
|
Synthesis of 2,6-Dimethyltyrosine-Like Amino Acids through Pinacolinamide-Enabled C-H Dimethylation of 4-Dibenzylamino Phenylalanine, file 237d6006-1f74-41c0-822a-6305ad99058b
|
2
|
|
EFFECT OF SARS-CoV-2 ON THE COAGULATION CASCADE IN COVID-19
ASSOCIATED COAGULOPATHIES, file bb3e6af4-9bb5-4d9e-83ef-c104f746169b
|
2
|
|
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway, file e309ade0-224b-3969-e053-3a05fe0a2c94
|
2
|
|
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands, file e309ade0-22e3-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade0-2863-3969-e053-3a05fe0a2c94
|
2
|
|
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence, file e309ade0-daaa-3969-e053-3a05fe0a2c94
|
2
|
|
Neuropeptide S receptor ligands: a patent review (2005-2016), file e309ade1-ad8b-3969-e053-3a05fe0a2c94
|
2
|
|
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT, file e309ade2-1971-3969-e053-3a05fe0a2c94
|
2
|
|
1,4-Dithiane-2,5-diol: An Attractive Platform for the Synthesis of Sulfur-Containing Functionalized Heterocycles, file e309ade2-1a64-3969-e053-3a05fe0a2c94
|
2
|
|
Bile Acid Binding Protein Functionalization Leads to a Fully Synthetic Rhodopsin Mimic, file e309ade2-50dd-3969-e053-3a05fe0a2c94
|
2
|
|
Novel halogenated synthetic cannabinoids impair sensorimotor functions in mice, file e309ade2-55ff-3969-e053-3a05fe0a2c94
|
2
|
|
Methiopropamine and its acute behavioral effects in mice: is there a gray zone in new psychoactive substances users?, file e309ade2-9720-3969-e053-3a05fe0a2c94
|
2
|
|
Spiropiperidine-Based Oligomycin-Analog Ligands To Counteract the Ischemia–Reperfusion Injury in a Renal Cell Model, file bcc00c68-9cfe-4a2a-9a1c-d8574a672d9c
|
1
|
|
(L)-Monomethyl Tyrosine (Mmt): New Synthetic Strategy via Bulky ‘Forced-Traceless’ Regioselective Pd-Catalyzed C(sp2)–H Activation, file d8bbb047-d27a-40e4-a61b-b5a27feb5efc
|
1
|
|
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ., file e309ade0-2134-3969-e053-3a05fe0a2c94
|
1
|
|
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with C alpha,alpha-dialkylated amino acids, file e309ade0-22df-3969-e053-3a05fe0a2c94
|
1
|
|
Structure-activity studies on neuropeptide S - Identification of the amino acid residues crucial for receptor activation, file e309ade0-22e0-3969-e053-3a05fe0a2c94
|
1
|
|
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist, file e309ade0-22e1-3969-e053-3a05fe0a2c94
|
1
|
|
Synthesis and biological activity of human neuropeptide S analogues modified in position 2, file e309ade0-2575-3969-e053-3a05fe0a2c94
|
1
|
|
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists., file e309ade0-2819-3969-e053-3a05fe0a2c94
|
1
|
|
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists., file e309ade0-2a4c-3969-e053-3a05fe0a2c94
|
1
|
|
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68)., file e309ade0-33a0-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-3e2a-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-4334-3969-e053-3a05fe0a2c94
|
1
|
|
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S
receptor: structure activity and pharmacological studies, file e309ade0-48f8-3969-e053-3a05fe0a2c94
|
1
|
|
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands, file e309ade0-662f-3969-e053-3a05fe0a2c94
|
1
|
|
JWH-018 impairs sensorimotor functions in mice, file e309ade0-8181-3969-e053-3a05fe0a2c94
|
1
|
|
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor, file e309ade0-8dfc-3969-e053-3a05fe0a2c94
|
1
|
|
Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity, file e309ade0-b883-3969-e053-3a05fe0a2c94
|
1
|
| Totale |
2.463 |