PRETI, Delia
 Distribuzione geografica
Continente #
NA - Nord America 8.263
EU - Europa 3.129
AS - Asia 1.798
SA - Sud America 32
Continente sconosciuto - Info sul continente non disponibili 6
AF - Africa 3
OC - Oceania 3
Totale 13.234
Nazione #
US - Stati Uniti d'America 8.229
DE - Germania 1.132
CN - Cina 869
IT - Italia 484
UA - Ucraina 474
SG - Singapore 390
TR - Turchia 375
GB - Regno Unito 280
RU - Federazione Russa 220
SE - Svezia 187
FI - Finlandia 172
VN - Vietnam 66
PL - Polonia 58
BE - Belgio 44
ID - Indonesia 36
CA - Canada 33
FR - Francia 25
BR - Brasile 21
HK - Hong Kong 16
NL - Olanda 14
CZ - Repubblica Ceca 11
IN - India 9
KR - Corea 9
LT - Lituania 9
PK - Pakistan 9
EU - Europa 6
CL - Cile 4
ES - Italia 4
IL - Israele 4
JP - Giappone 4
PE - Perù 4
AR - Argentina 3
AU - Australia 3
IR - Iran 3
AT - Austria 2
IE - Irlanda 2
PT - Portogallo 2
BG - Bulgaria 1
CH - Svizzera 1
DK - Danimarca 1
EG - Egitto 1
GR - Grecia 1
HR - Croazia 1
IQ - Iraq 1
JO - Giordania 1
KH - Cambogia 1
KZ - Kazakistan 1
MA - Marocco 1
MC - Monaco 1
MN - Mongolia 1
MX - Messico 1
NP - Nepal 1
RO - Romania 1
RS - Serbia 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
ZA - Sudafrica 1
Totale 13.234
Città #
Fairfield 1.100
Woodbridge 1.035
Ann Arbor 606
Ashburn 577
Houston 534
Jacksonville 531
Chandler 500
Santa Clara 427
Seattle 422
Wilmington 401
Cambridge 338
Singapore 322
Ferrara 215
Izmir 182
Beijing 178
Nanjing 153
Princeton 131
Boardman 120
San Diego 108
Shanghai 99
Milan 72
Helsinki 65
Dong Ket 64
Warsaw 58
Bremen 57
Nanchang 50
Shenyang 50
Los Angeles 46
Brussels 44
New York 41
Munich 36
Tianjin 36
Dearborn 35
Jakarta 35
San Mateo 32
Changsha 31
Hebei 30
London 30
Falls Church 27
Jiaxing 27
Redwood City 27
Mountain View 25
Addison 20
Philadelphia 18
Zhengzhou 18
Falkenstein 17
Frankfurt am Main 17
Washington 17
Kunming 16
Toronto 16
Guangzhou 15
Jinan 15
Auburn Hills 14
Hong Kong 14
Duncan 13
Indiana 13
Norwalk 12
Orange 12
Des Moines 11
Ferrara di Monte Baldo 11
Tappahannock 10
Amsterdam 9
Ottawa 9
Bari 8
Brno 8
Espoo 8
Kilburn 8
Mcallen 8
Montréal 8
Rome 8
Bologna 7
Ningbo 7
Padova 7
Verona 7
Chicago 6
Haikou 6
Hangzhou 6
Lanzhou 6
Taunsa 6
Prescot 5
Augusta 4
Düsseldorf 4
Grassano 4
Lima 4
Naples 4
West Jordan 4
Xian 4
Yellow Springs 4
Bournemouth 3
Chongqing 3
Florence 3
Leawood 3
Lugo 3
Mysore 3
Olomouc 3
Taizhou 3
Tel Aviv 3
Waban 3
Wandsworth 3
Woodland 3
Totale 9.381
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 342
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 196
A3 adenosine receptor antagonists: History and future perspectives 158
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 149
DNA minor groove binders as potential antitumor and antimicrobial agents 148
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 147
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 147
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 147
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 146
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 143
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 142
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 141
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 141
Hybrid molecules based on distamycin A as potential antitumor agents 141
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 139
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 137
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 137
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 137
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 135
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 135
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 135
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain 135
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 134
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 134
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 133
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 133
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 132
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 130
Recent improvements in the development of A2B adenosine receptor agonists. 129
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 128
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 127
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice 127
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 124
null 124
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 124
Allosteric enhancers for A(1) adenosine receptor 123
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation 122
Hybrid molecules between distamycin A and active moieties of antitumor agents 122
null 121
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 120
null 120
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 119
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 119
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. 118
null 118
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 117
Recent improvements in the development of A2B adenosine receptor agonists 117
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 116
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 116
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 116
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 116
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 115
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents 115
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked heterocycles as template for the adenosine receptor antagonism: medicinal chemistry approach and SAR considerations. 114
Ozone-induced hypertussive responses in rabbits and guinea pigs 114
null 112
Neuropeptide S receptor ligands: a patent review (2005-2016) 112
Recent developments in the field of adenosine receptor ligands. 111
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain 111
null 110
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 110
New 2-arylpyrazolo[4,3-c]quinoline derivates as potent and selective human A3 adenosine receptor antagonists 110
null 109
Synthesis and biological evaluation of novel N-6-[4-(substituted) sulfonamidophenylcarbamoyl]adenosine-5 '-uronamides as A(3) adenosine receptor agonists 107
The P2X7 receptor as a therapeutic target. 107
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 106
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents 106
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. 104
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 104
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 103
null 103
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 102
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 102
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 102
New strategies for the synthesis of A(3) adenosine receptor antagonists 101
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 100
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 99
Synthesis and biological evaluation of 2-substituted-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 99
Design, synthesis, and biological evaluation of C-9- and C-2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A(2A) and A(3) adenosine receptors antagonists 97
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 97
Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents 96
null 96
null 92
TRP channels as therapeutic targets in airway disorders: a patent review 91
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 91
Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies 91
Adenosine Modulates HIF-1 alpha, VEGF, IL-8, and Foam Cell Formation in a Human Model of Hypoxic Foam Cells 88
Recent improvements in the field of A(3) adenosine receptor ligands 88
Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice 88
Recent developments in the field of A2B and A3 adenosine receptors antagonists 87
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 87
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 87
null 87
null 87
Ligands for A(2B) adenosine receptor subtype 86
Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties 86
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 85
null 84
New pyrrolo [2,1-f] purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione derivates as potent and selective human A3 adenosine receptor antagonists 83
null 83
Totale 11.802
Categoria #
all - tutte 58.384
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.554
Totale 59.938


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.378 0 0 0 0 0 285 226 240 208 231 141 47
2020/20211.854 183 134 91 184 85 183 83 217 59 281 186 168
2021/20221.365 62 127 137 55 88 61 84 57 47 105 140 402
2022/20231.270 132 86 23 181 239 171 53 92 169 9 64 51
2023/2024831 59 96 49 25 60 137 41 90 25 19 22 208
2024/20251.268 85 99 271 144 350 319 0 0 0 0 0 0
Totale 13.418