PRETI, Delia
 Distribuzione geografica
Continente #
NA - Nord America 11.921
AS - Asia 5.034
EU - Europa 4.152
SA - Sud America 1.064
AF - Africa 112
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 5
Totale 22.295
Nazione #
US - Stati Uniti d'America 11.694
SG - Singapore 1.850
CN - Cina 1.522
DE - Germania 1.383
BR - Brasile 885
IT - Italia 665
UA - Ucraina 497
HK - Hong Kong 480
TR - Turchia 405
VN - Vietnam 399
GB - Regno Unito 387
RU - Federazione Russa 351
FI - Finlandia 250
SE - Svezia 211
CA - Canada 120
PL - Polonia 113
MX - Messico 94
FR - Francia 88
AR - Argentina 84
IN - India 74
ID - Indonesia 59
ZA - Sudafrica 54
BE - Belgio 44
BD - Bangladesh 43
JP - Giappone 42
NL - Olanda 41
ES - Italia 34
IQ - Iraq 31
EC - Ecuador 24
PK - Pakistan 24
CZ - Repubblica Ceca 17
KR - Corea 17
LT - Lituania 16
UZ - Uzbekistan 16
CO - Colombia 15
MA - Marocco 15
AT - Austria 14
IL - Israele 13
CL - Cile 12
VE - Venezuela 12
UY - Uruguay 11
KE - Kenya 10
PE - Perù 10
PY - Paraguay 10
IE - Irlanda 9
TN - Tunisia 9
AE - Emirati Arabi Uniti 8
EG - Egitto 8
SA - Arabia Saudita 8
KZ - Kazakistan 7
NP - Nepal 7
AZ - Azerbaigian 6
DZ - Algeria 6
EU - Europa 6
PT - Portogallo 6
AU - Australia 4
IR - Iran 4
JO - Giordania 4
LV - Lettonia 4
AL - Albania 3
AO - Angola 3
BG - Bulgaria 3
CR - Costa Rica 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GH - Ghana 2
HN - Honduras 2
JM - Giamaica 2
KG - Kirghizistan 2
QA - Qatar 2
RO - Romania 2
TH - Thailandia 2
TJ - Tagikistan 2
TT - Trinidad e Tobago 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BO - Bolivia 1
BY - Bielorussia 1
CH - Svizzera 1
CI - Costa d'Avorio 1
GA - Gabon 1
GL - Groenlandia 1
GR - Grecia 1
GT - Guatemala 1
HR - Croazia 1
HU - Ungheria 1
KH - Cambogia 1
KW - Kuwait 1
LU - Lussemburgo 1
MC - Monaco 1
MD - Moldavia 1
MK - Macedonia 1
MN - Mongolia 1
OM - Oman 1
PS - Palestinian Territory 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
Totale 22.292
Città #
Dallas 1.740
Singapore 1.106
Fairfield 1.100
Ashburn 1.095
Woodbridge 1.036
Ann Arbor 606
Houston 552
Jacksonville 533
Beijing 529
Chandler 500
Hong Kong 475
Santa Clara 461
Seattle 434
Wilmington 401
Cambridge 338
Ferrara 275
Munich 204
Izmir 182
Los Angeles 157
Nanjing 153
New York 138
Princeton 131
Boardman 120
Ho Chi Minh City 112
San Diego 109
Shanghai 104
Warsaw 101
São Paulo 82
Milan 79
Turku 76
Hanoi 74
Helsinki 66
Dong Ket 64
Mexico City 61
Bremen 57
Hefei 51
Nanchang 50
Shenyang 50
London 49
Tianjin 48
Montreal 46
Bologna 44
Brussels 44
Chicago 42
Jakarta 42
Brooklyn 41
Falkenstein 40
Frankfurt am Main 40
Orem 39
Tokyo 38
Dearborn 35
Rio de Janeiro 35
Atlanta 34
Changsha 34
Johannesburg 33
Phoenix 33
Denver 32
San Mateo 32
Toronto 31
Hebei 30
Poplar 28
Falls Church 27
Jiaxing 27
Redwood City 27
Chennai 26
Boston 25
Mountain View 25
Moscow 24
Brasília 22
Guangzhou 22
Stockholm 22
Addison 20
Belo Horizonte 20
Philadelphia 20
Amsterdam 19
Washington 19
Zhengzhou 19
Ankara 18
San Francisco 18
The Dalles 17
Kunming 16
Buffalo 15
Columbus 15
Council Bluffs 15
Jinan 15
Manchester 15
San Jose 15
Auburn Hills 14
Curitiba 14
Duncan 13
Guarulhos 13
Indiana 13
Norwalk 13
Rome 13
Tashkent 13
Nuremberg 12
Orange 12
Biên Hòa 11
Des Moines 11
Ferrara di Monte Baldo 11
Totale 14.958
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 1.174
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 1.038
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 252
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 234
A3 adenosine receptor antagonists: History and future perspectives 234
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 227
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 215
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 215
DNA minor groove binders as potential antitumor and antimicrobial agents 211
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 209
Allosteric enhancers for A(1) adenosine receptor 207
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 206
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 199
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 199
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 198
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 198
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 198
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 197
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 197
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 196
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 196
Hybrid molecules between distamycin A and active moieties of antitumor agents 194
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 192
Hybrid molecules based on distamycin A as potential antitumor agents 192
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 191
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 191
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 188
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice 188
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 187
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 186
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 185
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation 185
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 185
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 184
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 183
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 182
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 180
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 180
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 180
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 179
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain 178
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 178
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 177
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 177
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 176
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain 176
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 173
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 172
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 171
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents 171
Neuropeptide S receptor ligands: a patent review (2005-2016) 170
Recent developments in the field of adenosine receptor ligands. 169
Recent improvements in the development of A2B adenosine receptor agonists 168
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 167
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 166
Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies 164
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 163
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 162
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 160
Recent improvements in the development of A2B adenosine receptor agonists 160
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 158
New 2-arylpyrazolo[4,3-c]quinoline derivates as potent and selective human A3 adenosine receptor antagonists 157
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents 156
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 155
Ozone-induced hypertussive responses in rabbits and guinea pigs 155
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 154
Design, synthesis, and biological evaluation of C-9- and C-2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A(2A) and A(3) adenosine receptors antagonists 153
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 153
Synthesis and biological evaluation of novel N-6-[4-(substituted) sulfonamidophenylcarbamoyl]adenosine-5 '-uronamides as A(3) adenosine receptor agonists 152
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 151
New strategies for the synthesis of A(3) adenosine receptor antagonists 151
Adenosine modulates HIF-1α, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells 149
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system 149
Adenosine in a human model of Hypoxic foam cells 146
Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice 145
alpha-Halogenoacrylic Derivatives of Antitumor Agents 144
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 143
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 141
Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents 140
Synthesis and biological evaluation of 2-substituted-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 140
The P2X7 receptor as a therapeutic target 139
Adenosine modulates HIF-1, VEGF, IL-8 and foam cells formation in a human model of hypoxic foam cells 138
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 135
TRP channels as therapeutic targets in airway disorders: a patent review 135
Ligands for A(2B) adenosine receptor subtype 134
Recent improvements in the field of A(3) adenosine receptor ligands 133
New pyrrolo [2,1-f] purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione derivates as potent and selective human A3 adenosine receptor antagonists 132
Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties 131
COMPOSTI 1,3,8-TRIAZASPIRO E LORO USO COME MEDICAMENTI 127
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 126
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 126
null 124
Recent developments in the field of A2B and A3 adenosine receptors antagonists 122
null 121
null 120
null 118
Novel Mixed NOP/Opioid Receptor Peptide Agonists 117
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications 114
Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors 112
null 112
Totale 18.638
Categoria #
all - tutte 91.986
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.270
Totale 94.256


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.177 0 0 0 0 0 183 83 217 59 281 186 168
2021/20221.365 62 127 137 55 88 61 84 57 47 105 140 402
2022/20231.270 132 86 23 181 239 171 53 92 169 9 64 51
2023/2024831 59 96 49 25 60 137 41 90 25 19 22 208
2024/20253.344 85 99 271 144 350 322 103 194 474 348 494 460
2025/20267.011 975 962 2.043 1.139 1.350 542 0 0 0 0 0 0
Totale 22.505