PRETI, Delia
 Distribuzione geografica
Continente #
NA - Nord America 11.769
AS - Asia 4.909
EU - Europa 4.123
SA - Sud America 1.050
AF - Africa 103
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 5
Totale 21.966
Nazione #
US - Stati Uniti d'America 11.556
SG - Singapore 1.784
CN - Cina 1.514
DE - Germania 1.383
BR - Brasile 876
IT - Italia 660
UA - Ucraina 496
HK - Hong Kong 477
TR - Turchia 403
GB - Regno Unito 377
VN - Vietnam 376
RU - Federazione Russa 350
FI - Finlandia 250
SE - Svezia 210
CA - Canada 110
PL - Polonia 110
MX - Messico 90
FR - Francia 87
AR - Argentina 82
IN - India 67
ID - Indonesia 59
ZA - Sudafrica 50
BE - Belgio 44
JP - Giappone 41
BD - Bangladesh 39
NL - Olanda 39
ES - Italia 32
IQ - Iraq 26
EC - Ecuador 24
PK - Pakistan 24
CZ - Repubblica Ceca 17
KR - Corea 17
CO - Colombia 15
LT - Lituania 15
UZ - Uzbekistan 15
MA - Marocco 14
AT - Austria 13
IL - Israele 13
CL - Cile 12
UY - Uruguay 11
PE - Perù 10
PY - Paraguay 10
IE - Irlanda 9
KE - Kenya 9
VE - Venezuela 9
AE - Emirati Arabi Uniti 8
EG - Egitto 8
SA - Arabia Saudita 8
TN - Tunisia 8
KZ - Kazakistan 7
EU - Europa 6
PT - Portogallo 6
NP - Nepal 5
AU - Australia 4
AZ - Azerbaigian 4
DZ - Algeria 4
IR - Iran 4
JO - Giordania 4
LV - Lettonia 4
AL - Albania 3
AO - Angola 3
BG - Bulgaria 3
CR - Costa Rica 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GH - Ghana 2
HN - Honduras 2
JM - Giamaica 2
KG - Kirghizistan 2
RO - Romania 2
TH - Thailandia 2
TJ - Tagikistan 2
TT - Trinidad e Tobago 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BO - Bolivia 1
BY - Bielorussia 1
CH - Svizzera 1
CI - Costa d'Avorio 1
GA - Gabon 1
GL - Groenlandia 1
GR - Grecia 1
GT - Guatemala 1
HR - Croazia 1
HU - Ungheria 1
KH - Cambogia 1
KW - Kuwait 1
LU - Lussemburgo 1
MC - Monaco 1
MK - Macedonia 1
MN - Mongolia 1
OM - Oman 1
PS - Palestinian Territory 1
QA - Qatar 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SV - El Salvador 1
Totale 21.964
Città #
Dallas 1.737
Fairfield 1.100
Ashburn 1.056
Singapore 1.040
Woodbridge 1.036
Ann Arbor 606
Houston 547
Jacksonville 533
Beijing 529
Chandler 500
Hong Kong 473
Santa Clara 460
Seattle 434
Wilmington 401
Cambridge 338
Ferrara 273
Munich 204
Izmir 182
Nanjing 153
Los Angeles 149
Princeton 131
New York 125
Boardman 120
San Diego 109
Shanghai 104
Ho Chi Minh City 98
Warsaw 98
São Paulo 82
Milan 79
Turku 76
Hanoi 73
Helsinki 66
Dong Ket 64
Mexico City 59
Bremen 57
Hefei 51
Nanchang 50
Shenyang 50
Tianjin 48
London 45
Bologna 44
Brussels 44
Jakarta 42
Chicago 41
Montreal 41
Falkenstein 40
Frankfurt am Main 40
Brooklyn 39
Tokyo 37
Dearborn 35
Changsha 34
Rio de Janeiro 34
San Mateo 32
Atlanta 31
Hebei 30
Johannesburg 30
Toronto 29
Phoenix 28
Denver 27
Falls Church 27
Jiaxing 27
Orem 27
Redwood City 27
Poplar 26
Boston 25
Mountain View 25
Moscow 24
Brasília 22
Guangzhou 21
Stockholm 21
Addison 20
Belo Horizonte 20
Chennai 20
Philadelphia 20
Washington 19
Zhengzhou 19
Amsterdam 18
San Francisco 18
Ankara 16
Kunming 16
Buffalo 15
Columbus 15
Council Bluffs 15
Jinan 15
The Dalles 15
Auburn Hills 14
Manchester 14
Curitiba 13
Duncan 13
Guarulhos 13
Indiana 13
Norwalk 13
Nuremberg 12
Orange 12
Tashkent 12
Biên Hòa 11
Des Moines 11
Ferrara di Monte Baldo 11
Padova 11
Rome 11
Totale 14.731
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 1.171
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 1.035
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 247
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 230
A3 adenosine receptor antagonists: History and future perspectives 230
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 223
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 212
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 209
DNA minor groove binders as potential antitumor and antimicrobial agents 208
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 206
Allosteric enhancers for A(1) adenosine receptor 205
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 204
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 196
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 196
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 195
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 195
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 195
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 194
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 194
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 192
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 192
Hybrid molecules based on distamycin A as potential antitumor agents 191
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 190
Hybrid molecules between distamycin A and active moieties of antitumor agents 189
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 187
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 186
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 185
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 184
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 184
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice 184
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 180
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 180
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation 180
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 180
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 179
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 179
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 178
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 177
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 177
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 177
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain 177
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 175
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 174
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 174
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain 173
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 172
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 170
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 170
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 169
Neuropeptide S receptor ligands: a patent review (2005-2016) 169
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents 168
Recent developments in the field of adenosine receptor ligands. 167
Recent improvements in the development of A2B adenosine receptor agonists 166
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 163
Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies 163
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 163
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 159
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 159
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 158
Recent improvements in the development of A2B adenosine receptor agonists 157
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 156
New 2-arylpyrazolo[4,3-c]quinoline derivates as potent and selective human A3 adenosine receptor antagonists 155
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents 154
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 154
Ozone-induced hypertussive responses in rabbits and guinea pigs 153
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 153
Design, synthesis, and biological evaluation of C-9- and C-2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A(2A) and A(3) adenosine receptors antagonists 151
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 151
Synthesis and biological evaluation of novel N-6-[4-(substituted) sulfonamidophenylcarbamoyl]adenosine-5 '-uronamides as A(3) adenosine receptor agonists 149
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system 149
New strategies for the synthesis of A(3) adenosine receptor antagonists 149
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 146
Adenosine modulates HIF-1α, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells 145
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 143
Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice 143
Adenosine in a human model of Hypoxic foam cells 141
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 140
Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents 140
alpha-Halogenoacrylic Derivatives of Antitumor Agents 140
The P2X7 receptor as a therapeutic target 139
Synthesis and biological evaluation of 2-substituted-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 138
Adenosine modulates HIF-1, VEGF, IL-8 and foam cells formation in a human model of hypoxic foam cells 135
TRP channels as therapeutic targets in airway disorders: a patent review 134
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 133
Ligands for A(2B) adenosine receptor subtype 132
Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties 131
Recent improvements in the field of A(3) adenosine receptor ligands 131
New pyrrolo [2,1-f] purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione derivates as potent and selective human A3 adenosine receptor antagonists 130
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 125
null 124
COMPOSTI 1,3,8-TRIAZASPIRO E LORO USO COME MEDICAMENTI 124
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 124
null 121
null 120
Recent developments in the field of A2B and A3 adenosine receptors antagonists 119
null 118
Novel Mixed NOP/Opioid Receptor Peptide Agonists 115
null 112
Novel 1,3-Dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as Potent and Selective A2B Adenosine Receptor Antagonists 111
null 110
Totale 18.380
Categoria #
all - tutte 91.245
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.252
Totale 93.497


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.177 0 0 0 0 0 183 83 217 59 281 186 168
2021/20221.365 62 127 137 55 88 61 84 57 47 105 140 402
2022/20231.270 132 86 23 181 239 171 53 92 169 9 64 51
2023/2024831 59 96 49 25 60 137 41 90 25 19 22 208
2024/20253.344 85 99 271 144 350 322 103 194 474 348 494 460
2025/20266.680 975 962 2.043 1.139 1.350 211 0 0 0 0 0 0
Totale 22.174