IRIS
PRETI, Delia
 Distribuzione geografica
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Continente #
NA - Nord America 7081
EU - Europa 2814
AS - Asia 1128
SA - Sud America 10
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 3
AF - Africa 2
Totale 11044
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Nazione #
US - Stati Uniti d'America 7070
DE - Germania 1062
CN - Cina 658
UA - Ucraina 474
TR - Turchia 375
IT - Italia 366
GB - Regno Unito 226
RU - Federazione Russa 218
SE - Svezia 187
FI - Finlandia 104
BE - Belgio 76
VN - Vietnam 66
PL - Polonia 58
FR - Francia 23
CA - Canada 10
KR - Corea 9
IN - India 8
EU - Europa 6
NL - Olanda 5
CL - Cile 4
AR - Argentina 3
AU - Australia 3
BR - Brasile 3
ES - Italia 3
JP - Giappone 3
IL - Israele 2
IR - Iran 2
LT - Lituania 2
PK - Pakistan 2
PT - Portogallo 2
AT - Austria 1
CH - Svizzera 1
DK - Danimarca 1
EG - Egitto 1
GR - Grecia 1
HR - Croazia 1
ID - Indonesia 1
KH - Cambogia 1
MA - Marocco 1
MN - Mongolia 1
MX - Messico 1
RO - Romania 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 11044
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Città #
Fairfield 1100
Woodbridge 1035
Ann Arbor 606
Houston 534
Jacksonville 531
Chandler 500
Seattle 422
Ashburn 418
Wilmington 401
Cambridge 338
Izmir 182
Beijing 177
Ferrara 174
Nanjing 151
Princeton 131
San Diego 108
Boardman 85
Brussels 76
Dong Ket 64
Warsaw 58
Bremen 57
Milan 56
Nanchang 50
Shenyang 49
Tianjin 36
Dearborn 35
San Mateo 32
Changsha 31
Hebei 30
Falls Church 27
Jiaxing 27
Redwood City 27
Mountain View 25
Philadelphia 23
Addison 20
Kunming 16
Zhengzhou 16
Jinan 15
Auburn Hills 14
Munich 14
Duncan 13
Indiana 13
Norwalk 12
Orange 12
Des Moines 11
Ferrara di Monte Baldo 9
Guangzhou 9
London 9
Bari 8
Mcallen 8
Montréal 8
Los Angeles 7
New York 7
Ningbo 7
Shanghai 7
Verona 7
Chicago 6
Haikou 6
Helsinki 6
Lanzhou 6
Augusta 4
Bologna 4
Düsseldorf 4
Grassano 4
Hangzhou 4
Padova 4
Xian 4
Yellow Springs 4
Bournemouth 3
Chongqing 3
Leawood 3
Lugo 3
Mysore 3
Taizhou 3
Waban 3
Buenos Aires 2
Calvizzano 2
Hanoi 2
Hefei 2
Hyderabad 2
Torino 2
Toronto 2
Walnut 2
Washington 2
Andover 1
Ardabil 1
Athens 1
Bagnoli Di Sopra 1
Baotou 1
Beirã 1
Belgrade 1
Bratislava 1
Caen 1
Charlestown 1
Chengdu 1
Cormeilles-en-Parisis 1
Coventry 1
Curitiba 1
Dallas 1
Dehradun 1
Totale 7949
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Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 260
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 135
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 133
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 130
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 128
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 127
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 127
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 126
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 126
DNA minor groove binders as potential antitumor and antimicrobial agents 125
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 124
Novel 8-heterocyclyl xanthine derivatives in drug development - an update. 124
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 124
null 124
Hybrid molecules based on distamycin A as potential antitumor agents 124
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 122
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain 122
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 121
null 121
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 121
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 120
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 120
null 120
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 118
null 118
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 115
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 115
Recent improvements in the development of A2B adenosine receptor agonists. 114
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 114
A3 adenosine receptor antagonists: History and future perspectives 113
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 112
null 112
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 112
null 110
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 109
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 109
null 109
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 108
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N-(substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor. 108
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 107
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 107
Allosteric enhancers for A(1) adenosine receptor 106
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. 106
Recent improvements in the development of A2B adenosine receptor agonists 106
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents 106
Hybrid molecules between distamycin A and active moieties of antitumor agents 104
null 103
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 102
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation 101
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 101
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 100
The P2X7 receptor as a therapeutic target. 99
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 99
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice 99
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain 98
Neuropeptide S receptor ligands: a patent review (2005-2016) 98
Recent developments in the field of adenosine receptor ligands. 96
Ozone-induced hypertussive responses in rabbits and guinea pigs 96
null 96
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 96
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 95
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. 95
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 93
New 2-arylpyrazolo[4,3-c]quinoline derivates as potent and selective human A3 adenosine receptor antagonists 93
null 92
Synthesis and biological evaluation of 2-substituted-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 91
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 91
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked heterocycles as template for the adenosine receptor antagonism: medicinal chemistry approach and SAR considerations. 90
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents 88
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 88
null 87
null 87
Synthesis and biological evaluation of novel N-6-[4-(substituted) sulfonamidophenylcarbamoyl]adenosine-5 '-uronamides as A(3) adenosine receptor agonists 86
Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents 86
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 84
TRP channels as therapeutic targets in airway disorders: a patent review 84
null 84
New strategies for the synthesis of A(3) adenosine receptor antagonists 83
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 83
null 83
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 83
null 82
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 82
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 82
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 80
Recent developments in the field of A2B and A3 adenosine receptors antagonists 79
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 78
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 78
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 78
Design, synthesis, and biological evaluation of C-9- and C-2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A(2A) and A(3) adenosine receptors antagonists 77
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 76
Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties 74
null 73
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 73
New pyrrolo [2,1-f] purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione derivates as potent and selective human A3 adenosine receptor antagonists 71
Recent improvements in the field of A(3) adenosine receptor ligands 71
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 70
Ligands for A(2B) adenosine receptor subtype 68
Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies 68
alpha-Halogenoacrylic Derivatives of Antitumor Agents 67
Totale 10199
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Categoria #
all - tutte 20007
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 468
Totale 20475
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/2018240 0000 00 00 14162613
2018/20191861 56595491 8021 20818 117258359540
2019/20202469 3789483356 180285 226240 20823114147
2020/20211854 18313491184 85183 83217 59281186168
2021/20221365 6212713755 8861 8457 47105140402
2022/20231167 1328623181 239171 62129 144000
Totale 11216