PRETI, Delia
 Distribuzione geografica
Continente #
NA - Nord America 13.286
EU - Europa 8.258
AS - Asia 6.567
SA - Sud America 1.248
AF - Africa 158
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 7
Totale 29.531
Nazione #
US - Stati Uniti d'America 13.014
FI - Finlandia 4.008
SG - Singapore 2.258
CN - Cina 1.726
DE - Germania 1.400
BR - Brasile 981
VN - Vietnam 843
IT - Italia 724
HK - Hong Kong 541
UA - Ucraina 507
TR - Turchia 427
GB - Regno Unito 422
RU - Federazione Russa 357
FR - Francia 229
SE - Svezia 213
JP - Giappone 143
IN - India 139
CA - Canada 135
PL - Polonia 117
AR - Argentina 109
MX - Messico 104
BD - Bangladesh 88
ID - Indonesia 83
ZA - Sudafrica 67
IQ - Iraq 58
NL - Olanda 54
PK - Pakistan 47
ES - Italia 46
BE - Belgio 45
EC - Ecuador 34
CO - Colombia 32
UZ - Uzbekistan 27
SA - Arabia Saudita 22
MA - Marocco 21
CL - Cile 20
VE - Venezuela 20
KR - Corea 19
LT - Lituania 19
CZ - Repubblica Ceca 18
IL - Israele 18
MY - Malesia 17
UY - Uruguay 17
PY - Paraguay 16
AT - Austria 15
IE - Irlanda 15
KE - Kenya 15
PE - Perù 14
PH - Filippine 14
TN - Tunisia 13
EG - Egitto 12
AE - Emirati Arabi Uniti 10
JO - Giordania 10
KZ - Kazakistan 10
PT - Portogallo 10
DZ - Algeria 9
SK - Slovacchia (Repubblica Slovacca) 9
TH - Thailandia 9
AZ - Azerbaigian 8
NP - Nepal 8
TW - Taiwan 7
CR - Costa Rica 6
EU - Europa 6
JM - Giamaica 6
AL - Albania 5
AU - Australia 5
BO - Bolivia 5
GR - Grecia 5
HR - Croazia 5
IR - Iran 5
LV - Lettonia 5
AO - Angola 4
KG - Kirghizistan 4
PS - Palestinian Territory 4
RS - Serbia 4
BG - Bulgaria 3
BH - Bahrain 3
CH - Svizzera 3
GA - Gabon 3
GH - Ghana 3
GT - Guatemala 3
HU - Ungheria 3
MD - Moldavia 3
NI - Nicaragua 3
OM - Oman 3
PA - Panama 3
QA - Qatar 3
BA - Bosnia-Erzegovina 2
BY - Bielorussia 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
HN - Honduras 2
KH - Cambogia 2
LB - Libano 2
MN - Mongolia 2
RO - Romania 2
SV - El Salvador 2
TJ - Tagikistan 2
TT - Trinidad e Tobago 2
AM - Armenia 1
Totale 29.505
Città #
Helsinki 3.819
Dallas 1.742
Singapore 1.485
Ashburn 1.383
Fairfield 1.100
Woodbridge 1.036
San Jose 718
Ann Arbor 606
Houston 554
Beijing 548
Jacksonville 533
Hong Kong 516
Chandler 500
Santa Clara 485
Seattle 436
Wilmington 402
Cambridge 338
Ferrara 282
Ho Chi Minh City 250
Munich 204
Hanoi 193
Izmir 184
Los Angeles 172
Nanjing 154
New York 152
Princeton 131
Tokyo 131
Boardman 121
Lauterbourg 112
Shanghai 110
San Diego 109
Warsaw 103
São Paulo 93
Council Bluffs 88
Milan 81
Turku 76
Dong Ket 64
Orem 62
Mexico City 61
Bremen 57
London 54
Hefei 51
Montreal 51
Nanchang 50
Shenyang 50
Bologna 49
Tianjin 49
Frankfurt am Main 48
Brussels 45
Chicago 45
Jakarta 45
Atlanta 42
Brooklyn 42
Falkenstein 40
Rio de Janeiro 39
Johannesburg 38
Chennai 37
Phoenix 37
Changsha 35
Dearborn 35
Da Nang 34
Toronto 33
Denver 32
San Mateo 32
Hebei 30
Poplar 29
Falls Church 27
Jiaxing 27
Redwood City 27
Amsterdam 26
Guangzhou 26
Haiphong 26
Moscow 26
Boston 25
Mountain View 25
Tashkent 24
Baghdad 23
Brasília 23
Stockholm 23
Ankara 22
Belo Horizonte 22
San Francisco 22
Addison 20
Buffalo 20
Manchester 20
Philadelphia 20
Washington 20
Zhengzhou 20
Mumbai 19
The Dalles 19
Curitiba 18
Rome 17
Hải Dương 16
Jinan 16
Kunming 16
Biên Hòa 15
Columbus 15
Dublin 15
Nuremberg 15
Auburn Hills 14
Totale 20.972
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.087
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 2.933
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 314
A3 adenosine receptor antagonists: History and future perspectives 282
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 272
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 259
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 256
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 245
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 243
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 242
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 238
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 237
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 237
DNA minor groove binders as potential antitumor and antimicrobial agents 236
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 236
Allosteric enhancers for A(1) adenosine receptor 234
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 234
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 234
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 228
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 226
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 224
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 222
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice 222
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 220
Hybrid molecules between distamycin A and active moieties of antitumor agents 220
Hybrid molecules based on distamycin A as potential antitumor agents 218
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 217
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation 215
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 214
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 208
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 207
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain 207
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 207
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 206
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 206
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 206
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 205
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 203
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 203
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 202
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain 202
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 200
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 200
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 199
Neuropeptide S receptor ligands: a patent review (2005-2016) 199
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 198
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents 197
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 197
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 196
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 196
Recent developments in the field of adenosine receptor ligands. 195
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 192
Recent improvements in the development of A2B adenosine receptor agonists 192
Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies 189
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 189
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 188
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 186
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 186
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 185
Adenosine in a human model of Hypoxic foam cells 184
alpha-Halogenoacrylic Derivatives of Antitumor Agents 184
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 183
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 181
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 180
New strategies for the synthesis of A(3) adenosine receptor antagonists 180
Adenosine modulates HIF-1, VEGF, IL-8 and foam cells formation in a human model of hypoxic foam cells 179
New 2-arylpyrazolo[4,3-c]quinoline derivates as potent and selective human A3 adenosine receptor antagonists 178
Ozone-induced hypertussive responses in rabbits and guinea pigs 177
Recent improvements in the development of A2B adenosine receptor agonists 176
Design, synthesis, and biological evaluation of C-9- and C-2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A(2A) and A(3) adenosine receptors antagonists 174
Adenosine modulates HIF-1α, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells 173
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 171
Synthesis and biological evaluation of novel N-6-[4-(substituted) sulfonamidophenylcarbamoyl]adenosine-5 '-uronamides as A(3) adenosine receptor agonists 169
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents 169
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system 169
Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents 169
Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice 169
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 168
Recent improvements in the field of A(3) adenosine receptor ligands 165
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 164
Synthesis and biological evaluation of 2-substituted-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 163
Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors 162
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 160
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 159
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 157
The P2X7 receptor as a therapeutic target 155
Ligands for A(2B) adenosine receptor subtype 154
TRP channels as therapeutic targets in airway disorders: a patent review 154
Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties 153
COMPOSTI 1,3,8-TRIAZASPIRO E LORO USO COME MEDICAMENTI 153
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications 150
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 149
New pyrrolo [2,1-f] purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione derivates as potent and selective human A3 adenosine receptor antagonists 148
Novel Mixed NOP/Opioid Receptor Peptide Agonists 148
Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase 136
Recent developments in the field of A2B and A3 adenosine receptors antagonists 136
Novel 1,3-Dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as Potent and Selective A2B Adenosine Receptor Antagonists 136
COMPOSTI SOLFONAMMIDICI COME INIBITORI DELL’INFLAMMASOMA NLRP3 E LORO USO COME MEDICAMENTI 135
Medicinal chemistry of the a(3) adenosine receptor: agonists, antagonists, and receptor engineering 134
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents 131
Totale 25.026
Categoria #
all - tutte 101.795
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.406
Totale 104.201


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021635 0 0 0 0 0 0 0 0 0 281 186 168
2021/20221.365 62 127 137 55 88 61 84 57 47 105 140 402
2022/20231.270 132 86 23 181 239 171 53 92 169 9 64 51
2023/2024831 59 96 49 25 60 137 41 90 25 19 22 208
2024/20253.344 85 99 271 144 350 322 103 194 474 348 494 460
2025/202614.251 975 962 2.043 1.139 1.350 682 1.077 514 4.551 958 0 0
Totale 29.745