| Nome |
# |
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History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents, file e309ade3-e533-3969-e053-3a05fe0a2c94
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150
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|
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity, file e309ade4-cfe7-3969-e053-3a05fe0a2c94
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147
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Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors, file e309ade2-3430-3969-e053-3a05fe0a2c94
|
127
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Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction, file e309ade3-fc29-3969-e053-3a05fe0a2c94
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108
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The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives, file e309ade0-c110-3969-e053-3a05fe0a2c94
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94
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The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain, file e309ade4-3029-3969-e053-3a05fe0a2c94
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94
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Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors, file e309ade3-aff3-3969-e053-3a05fe0a2c94
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66
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Neuropeptide S receptor ligands: a patent review (2005-2016), file e309ade3-a082-3969-e053-3a05fe0a2c94
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65
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Novel Mixed NOP/Opioid Receptor Peptide Agonists, file e309ade4-c82b-3969-e053-3a05fe0a2c94
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62
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Ozone-induced hypertussive responses in rabbits and guinea pigs, file e309ade1-258e-3969-e053-3a05fe0a2c94
|
54
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Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach, file e309ade1-e366-3969-e053-3a05fe0a2c94
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54
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Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands, file e309ade3-dd14-3969-e053-3a05fe0a2c94
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53
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Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors, file e309ade3-b3df-3969-e053-3a05fe0a2c94
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51
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Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies, file e309ade2-1260-3969-e053-3a05fe0a2c94
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44
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Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2, file e309ade2-f967-3969-e053-3a05fe0a2c94
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36
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The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel, file e309ade3-ecd6-3969-e053-3a05fe0a2c94
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31
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Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice, file e309ade3-e324-3969-e053-3a05fe0a2c94
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29
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Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor, file e309ade3-cfd0-3969-e053-3a05fe0a2c94
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25
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Ozone-induced hypertussive responses in rabbits and guinea pigs, file e309ade3-95f2-3969-e053-3a05fe0a2c94
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24
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The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice, file e309ade0-c888-3969-e053-3a05fe0a2c94
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16
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Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening, file e309ade2-d995-3969-e053-3a05fe0a2c94
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16
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History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents, file e309ade0-cb8f-3969-e053-3a05fe0a2c94
|
9
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null, file e309ade0-cb9c-3969-e053-3a05fe0a2c94
|
8
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Non-neuronal TRPA1 encodes mechanical allodynia associated with neurogenic inflammation and partial nerve injury in rats, file 69bcd681-c202-47f8-93ca-e4d2f1c2f372
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6
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7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists, file e309ade0-ccd8-3969-e053-3a05fe0a2c94
|
5
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A3 adenosine receptor antagonists: History and future perspectives, file e309ade1-88ae-3969-e053-3a05fe0a2c94
|
5
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|
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction, file e309ade1-f663-3969-e053-3a05fe0a2c94
|
5
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Synthesis and biological effects of novel 2-amino-3-(4-chlorobenzoyl)-4- substituted thiophenes as allosteric enhancers of the A1 adenosine receptor, file e309ade2-bea4-3969-e053-3a05fe0a2c94
|
5
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Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor, file e309ade0-cb8b-3969-e053-3a05fe0a2c94
|
4
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7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation, file e309ade0-cb90-3969-e053-3a05fe0a2c94
|
4
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|
NOP-Targeted Peptide Ligands, file e309ade2-4d6f-3969-e053-3a05fe0a2c94
|
4
|
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Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors, file e309ade2-4f09-3969-e053-3a05fe0a2c94
|
4
|
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Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents, file e309ade2-beae-3969-e053-3a05fe0a2c94
|
4
|
|
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists, file e309ade0-2fe0-3969-e053-3a05fe0a2c94
|
3
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|
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor, file e309ade0-3ba0-3969-e053-3a05fe0a2c94
|
3
|
|
null, file e309ade0-a439-3969-e053-3a05fe0a2c94
|
3
|
|
null, file e309ade1-2d29-3969-e053-3a05fe0a2c94
|
3
|
|
Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice, file e309ade2-34b2-3969-e053-3a05fe0a2c94
|
3
|
|
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene, file e309ade0-415a-3969-e053-3a05fe0a2c94
|
2
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|
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents, file e309ade0-45e8-3969-e053-3a05fe0a2c94
|
2
|
|
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation, file e309ade0-bd50-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade0-c45d-3969-e053-3a05fe0a2c94
|
2
|
|
Neuropeptide S receptor ligands: a patent review (2005-2016), file e309ade1-ad8b-3969-e053-3a05fe0a2c94
|
2
|
|
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer, file eb4e9293-771e-4d27-adee-79487c1b2019
|
2
|
|
Spiropiperidine-Based Oligomycin-Analog Ligands To Counteract the Ischemia–Reperfusion Injury in a Renal Cell Model, file bcc00c68-9cfe-4a2a-9a1c-d8574a672d9c
|
1
|
|
null, file e309ade0-4754-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-485d-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-ccae-3969-e053-3a05fe0a2c94
|
1
|
|
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety, file e309ade0-edcf-3969-e053-3a05fe0a2c94
|
1
|
|
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents, file e309ade4-2979-3969-e053-3a05fe0a2c94
|
1
|
| Totale |
1.442 |