Distribuzione geografica
Continente #
NA - Nord America 11181
EU - Europa 3657
AS - Asia 2094
OC - Oceania 23
SA - Sud America 15
AF - Africa 13
Continente sconosciuto - Info sul continente non disponibili 11
Totale 16994
Nazione #
US - Stati Uniti d'America 11145
CN - Cina 1448
IT - Italia 798
UA - Ucraina 735
PL - Polonia 577
DE - Germania 549
TR - Turchia 511
SE - Svezia 326
GB - Regno Unito 266
FI - Finlandia 167
FR - Francia 74
BE - Belgio 60
VN - Vietnam 56
CA - Canada 30
NL - Olanda 29
RU - Federazione Russa 25
AU - Australia 19
IN - India 18
IR - Iran 15
EU - Europa 10
GR - Grecia 9
RO - Romania 9
CH - Svizzera 8
ES - Italia 7
ID - Indonesia 7
MY - Malesia 7
DZ - Algeria 6
CL - Cile 5
JP - Giappone 5
TN - Tunisia 5
TW - Taiwan 5
AT - Austria 4
BR - Brasile 4
CO - Colombia 4
KR - Corea 4
NZ - Nuova Zelanda 4
IL - Israele 3
MX - Messico 3
TH - Thailandia 3
DM - Dominica 2
EE - Estonia 2
MK - Macedonia 2
PK - Pakistan 2
PT - Portogallo 2
RS - Serbia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AR - Argentina 1
BD - Bangladesh 1
BG - Bulgaria 1
BT - Bhutan 1
BW - Botswana 1
CZ - Repubblica Ceca 1
EG - Egitto 1
GT - Guatemala 1
HK - Hong Kong 1
IE - Irlanda 1
IQ - Iraq 1
JO - Giordania 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LI - Liechtenstein 1
MT - Malta 1
NO - Norvegia 1
PE - Perù 1
QA - Qatar 1
SA - Arabia Saudita 1
Totale 16994
Città #
Woodbridge 1560
Fairfield 1497
Ann Arbor 981
Chandler 968
Jacksonville 918
Houston 913
Ashburn 621
Wilmington 577
Seattle 576
Warsaw 576
Beijing 521
Cambridge 499
Ferrara 365
Izmir 332
Nanjing 311
Princeton 237
Boardman 152
Addison 126
Bremen 120
San Diego 105
Milan 88
Nanchang 77
Shenyang 74
Brussels 58
Hebei 57
Tianjin 57
Redwood City 56
Dong Ket 55
Jiaxing 53
Changsha 50
Dearborn 42
Falls Church 39
Bologna 37
Jinan 34
Mountain View 33
Des Moines 29
Guangzhou 29
Auburn Hills 26
Ningbo 26
Norwalk 26
Zhengzhou 23
Orange 20
Chicago 19
Leiden 17
Hefei 16
Kunming 16
San Mateo 16
London 15
Leawood 13
Lanzhou 12
Philadelphia 12
San Jose 12
Indiana 11
Los Angeles 11
Augusta 10
Changchun 10
Munich 10
New York 10
Taizhou 10
Ferrara di Monte Baldo 8
Haikou 8
Shanghai 8
Düsseldorf 7
Hangzhou 7
Mcallen 7
Montréal 7
Chengdu 6
Napoli 6
Rome 6
Toronto 6
Granada 5
Helsinki 5
Jakarta 5
Monmouth Junction 5
Palermo 5
Sydney 5
Bogotá 4
Fremont 4
Redmond 4
San Francisco 4
Taipei 4
Taiyuan 4
Ardabil 3
Basel 3
Bexhill 3
Cagliari 3
Calgary 3
Chongqing 3
Fars 3
Fort Worth 3
Harvard 3
Kansas City 3
Kundan 3
New Delhi 3
Rotterdam 3
Stockholm 3
Verona 3
Walnut 3
Wuhan 3
Albert Park 2
Totale 13347
Nome #
An Aγ-globin G->A gene polymorphism associated with β(0)39 thalassemia globin gene and high fetal hemoglobin production 291
A validated cellular biobank for β-thalassemia 254
1,2,4-triazoles. Improved synthesis of 5-substituited 4-amino-3mercato-(4H)-1,2,4 triazoles and a facile route to 3,6-disubstituited 1,24-triazolo[3,4b][1,3,4]thiadiazoles 187
A validated THALAMOSS cellular biobank for β-thalassemia 173
Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis 169
Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports 155
Generation and characterization of a transgenic mouse carrying a functional human β-globin gene with the IVSI-6 thalassemia mutation 152
Differential Effects of Angelicin Analogues on NF-kB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells 151
In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa 148
Design, synthesis and biological activity of a novel Rutin analogue with improved lipid soluble properties 147
Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen 147
Bis(dimethylsulfoxide)carbonateplatinum(II), a new synthon for a low-impact, versatile synthetic route to anticancer Pt carboxylates 143
The (A)gamma(+25 G -> A) polymorphism is associated with high HbF production leading to a decrease in binding activity of the LYAR transcription factor to the (A)gamma-globin gene in beta-thalassemia patients 140
Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells 134
Exploring the effect of chirality on the therapeutic potential of N-alkyl-deoxyiminosugars: anti-inflammatory response to Pseudomonas aeruginosa infections for application in CF lung disease 134
Synthesis and characterization of Pt complexes containing dichloroacetate (DCA), designed for dual anticancer action 133
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 131
Phloridzin derivatives inhibiting proinflammatory cytokine expression in human cystic fibrosis IB3-1 cells 131
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222 129
Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells 126
MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells 125
A Novel Frameshift Mutation (+A) at Codon 18 of the beta-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and deltabeta-Thalassemia 123
In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa 122
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones 120
Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia 117
Structure and Biological Activity of Furocoumarins 116
Analytic and dynamic secretory profile of patient-derived cytokine-Induced killer cells 116
Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells 115
null 114
Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line 113
An antisense peptide nucleic acid against Pseudomonas aeruginosa inhibiting bacterial-induced inflammatory responses in the cystic fibrosis IB3-1 cellular model system 109
Plants with antitumor properties:from biologically active molecules to drugs 108
C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells. 108
Ethanolic extract from Hemidesmus indicus (Linn) displays otoprotectant activities on organotypic cultures without interfering on gentamicin uptake. 108
Effects on erythroid differentiation of platinum(II) complexes of synthetic bile acid derivatives 108
null 107
Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum 106
Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines 105
Antiproliferative activity of essential oils derived from plants belonging to the Magnoliophyta division 105
Induction of apoptosis of human glioma cell lines: Effects of combined treatment with corilagin and temozolomide 104
A peptide nucleic acid against microrna miR-145-5p enhances the expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells 104
null 103
Possible detection of Autologous Blood Transfusion (ABT) based on circulating plasma microRNAs involved in erythroid differentiation and fetal hemoglobin induction 103
Phytochemical and pharmacological properties of essential oils from Cedrus species 103
Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives 103
miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs 102
Targeting Transcription Factor Activity as a Strategy to Inhibit Pro-Inflammatory Genes Involved in Cystic Fibrosis: Decoy Oligonucleotides and Low-Molecular Weight Compounds 102
Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin 102
Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression 102
New furan side tetracyclic allopsoralen derivatives: synthesis and photobiological evaluation 101
A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction 101
Expression of Estrogen Receptor a Gene in Breast Cancer Cells Treated with Transcription Factor Decoy is Modulated by Bangladeshi Natural Plant Extracts. 100
Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts 100
null 99
Synthesis and Biological Evaluation of 2-(3’,4’,5’-Trimethoxybenzoyl)-3-N,N-Dimethylamino Benzo[b]furan Derivatives as Inhibitors of Tubulin Polymerization 99
null 98
Generation and molecular characterization of a transgenic mouse line carrying a mutated human IVS-I-6 thalassemia beta-globin gene 98
Targeting microRNAs involved in human diseases: A novel approach for modification of gene expression and drug development 98
Design, synthesis and binding at cloned muscarinic receptors of N-[5-(1'-substituted-acetoxymethyl)-3-oxadiazolyl] and N-[4-(1'-substituted-acetoxymethyl)-2-dioxolanyl] dialkyl amines. 98
GBA2-Encoded β-Glucosidase Activity Is Involved in the Inflammatory Response to Pseudomonas aeruginosa. 97
Phytochemical analysis and in vitro evaluation of the biological activity against herpes simplex virus type 1 (HSV-1) of Cedrus libani A. Rich 97
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles 96
Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites 96
Modulators of Sphingolipid Metabolism Reduce Lung Inflammation 95
PCR detection of segmented filamentous bacteria in the terminal ileum of patients with ulcerative colitis 95
Erythroid differentiation ability of butyric acid analogues: Identification of basal chemical structures of new inducers of foetal haemoglobin 94
Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity 94
null 93
null 93
Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients. 93
Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β(0)-Thalassemia Families with High Fetal Hemoglobin Levels 92
Phloridzin derivatives inhibiting pro-inflammatory cytokine expression in human cystic fibrosis IB3-1 cells 92
Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells 91
Facile synthesis of 2-nitroalkanols by Tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones 91
Involvement of miRNA in erythroid differentiation 91
Pharmacological Modulators of Sphingolipid Metabolism for the Treatment of Cystic Fibrosis Lung Inflammation 91
Antitumor effects of new synthetic isoxazole derivatives 91
null 90
PNAs targeting BCL11A at the miR-210 binding sites down-regulate BCL11A and up-regulate gamma-globin mRNA 89
High levels of apoptosis induced in human glioma cell lines by combined treatment with antagomiR PNAs and pre-miRNA molecules 89
null 88
Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis 88
null 88
null 87
Virtual screening against nuclear factor kB (NF-kB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis 86
Comparative antiproliferative activities of wood and seeds essential oils of Juniperus oxycedrus L. against K562 human chronic myelogenus leukemia cells. 86
null 86
Corilagin is a potent inhibitor of NF-kappaB activity and expression of TNF-alpha induced IL-8 gene in cystic fibrosis IB3-1 cells 85
Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts. 85
Effects of Medicinal Plant Extracts on Molecular Interactions between DNA and Transcription Factors 85
Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport 85
Anti-inflammatory activity of novel 4,6,4’-trimethylangelicin’s analogues: effects on the NF-kB activity and IL-8 expression in Cystic Fibrosis IB3-1 cells 84
Molecular mechanism of action of trimethylangelicin derivatives as CFTR modulators 84
Palladium (0) olefin complexes bearing purine-based N-heterocyclic carbenes and 1,3,5-triaza-7-phosphaadamantane (PTA): Synthesis, characterization and antiproliferative activity toward human ovarian cancer cell lines 84
null 82
null 81
null 81
A PLE-based resolution of cocaine, pseudococaine and 6-and 7-methoxylated cocaine analogues 81
Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia 81
Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients 80
Totale 10977
Categoria #
all - tutte 33151
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 814
Totale 33965

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/2018234 0000 00 00 68894829
2018/20192621 22222551 2956 27071 267427488893
2019/20204013 643128126511 310444 324359 39147822673
2020/20213417 216245187331 128297 257343 111449532321
2021/20222254 2041959093 138106 124119 82212228663
2022/20232082 26020462289 415294 145214 199000
Totale 17510