| Nome |
# |
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Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity, file e309ade1-dc47-3969-e053-3a05fe0a2c94
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214
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Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis, file e309ade0-f854-3969-e053-3a05fe0a2c94
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213
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Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports, file e309ade2-140d-3969-e053-3a05fe0a2c94
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188
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Moringa oleifera leaf extracts as multifunctional ingredients for “natural and organic” sunscreens and photoprotective preparations, file e309ade1-dc7e-3969-e053-3a05fe0a2c94
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138
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An Aγ-globin G->A gene polymorphism associated with β(0)39 thalassemia globin gene and high fetal hemoglobin production, file e309ade1-7733-3969-e053-3a05fe0a2c94
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132
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Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia, file e309ade2-4e76-3969-e053-3a05fe0a2c94
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115
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Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones, file e309ade3-9e51-3969-e053-3a05fe0a2c94
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106
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A validated cellular biobank for β-thalassemia, file e309ade0-ee58-3969-e053-3a05fe0a2c94
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71
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Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells, file e309ade0-ad71-3969-e053-3a05fe0a2c94
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67
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Differential Effects of Angelicin Analogues on NF-kB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells, file e309ade1-8832-3969-e053-3a05fe0a2c94
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67
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MicroRNAs and Long Non-coding RNAs in Genetic Diseases, file e309ade2-1ab8-3969-e053-3a05fe0a2c94
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64
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Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells, file e309ade2-4e78-3969-e053-3a05fe0a2c94
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63
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MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells, file e309ade2-d9f2-3969-e053-3a05fe0a2c94
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62
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A peptide nucleic acid against microrna miR-145-5p enhances the expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells, file e309ade1-a84d-3969-e053-3a05fe0a2c94
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58
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Pro‑apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro, file e309ade2-ef0e-3969-e053-3a05fe0a2c94
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58
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Molecular mechanism of action of trimethylangelicin derivatives as CFTR modulators, file e309ade4-3a26-3969-e053-3a05fe0a2c94
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57
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Analytic and dynamic secretory profile of patient-derived cytokine-Induced killer cells, file e309ade1-81df-3969-e053-3a05fe0a2c94
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52
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Design, synthesis and biological activity of a novel Rutin analogue with improved lipid soluble properties, file e309ade4-8099-3969-e053-3a05fe0a2c94
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52
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Generation and characterization of a transgenic mouse carrying a functional human β-globin gene with the IVSI-6 thalassemia mutation, file e309ade0-a54c-3969-e053-3a05fe0a2c94
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51
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Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients, file e309ade0-f426-3969-e053-3a05fe0a2c94
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50
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Immunomodulatory and anti-inflammatory activity in vitro and in vivo of a novel antimicrobial candidate, file e309ade1-2e0b-3969-e053-3a05fe0a2c94
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50
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Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells, file e309ade2-d6a6-3969-e053-3a05fe0a2c94
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49
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Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites, file e309ade0-ee55-3969-e053-3a05fe0a2c94
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44
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Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis, file e309ade2-d08c-3969-e053-3a05fe0a2c94
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42
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Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles, file e309ade2-629f-3969-e053-3a05fe0a2c94
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40
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Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line, file e309ade2-82f2-3969-e053-3a05fe0a2c94
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40
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Antiproliferative activity of essential oils derived from plants belonging to the Magnoliophyta division, file e309ade4-764f-3969-e053-3a05fe0a2c94
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35
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UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation, file e309ade2-1ad9-3969-e053-3a05fe0a2c94
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31
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An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue, file e309ade2-8eb9-3969-e053-3a05fe0a2c94
|
24
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Treatment of human airway epithelial Calu-3 cells with a peptide-nucleic acid (PNA) targeting the microRNA miR-101-3p is associated with increased expression of the cystic fibrosis Transmembrane Conductance Regulator () gene, file f8818e72-4359-45e8-bda1-5ad1b8cc735f
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18
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High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222, file e309ade3-1797-3969-e053-3a05fe0a2c94
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12
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Synthesis and characterization of Pt complexes containing dichloroacetate (DCA), designed for dual anticancer action, file e309ade3-a50d-3969-e053-3a05fe0a2c94
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12
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Expression of γ-globin genes in β-thalassemia patients treated with sirolimus: results from a pilot clinical trial (Sirthalaclin), file 330010a8-57ab-464b-ac76-8393bc420f74
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11
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β-Sitosterol Reduces the Expression of Chemotactic Cytokine Genes in Cystic Fibrosis Bronchial Epithelial Cells, file e309ade1-69e2-3969-e053-3a05fe0a2c94
|
11
|
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Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones, file e309ade2-2b91-3969-e053-3a05fe0a2c94
|
10
|
|
In-vitro evaluation of antioxidant, antiproliferative and photo-protective activities of benzimidazolehydrazone derivatives, file e309ade2-fa00-3969-e053-3a05fe0a2c94
|
9
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A peptide nucleic acid (PNA) masking the miR-145-5p binding site of the 3’UTR of the cystic fibrosis transmembrane conductance regulator (CFTR) mRNA enhances CFTR expression in Calu-3 cells, file e309ade5-219c-3969-e053-3a05fe0a2c94
|
9
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New synthetic isoxazole derivatives as potent inducer of fetal hemoglobin (HbF) in beta-thalassemia, file e309ade5-3258-3969-e053-3a05fe0a2c94
|
9
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Novel lipidized derivatives of the bioflavonoid hesperidin: Dermatological, cosmetic and chemopreventive applications, file e309ade2-0b9e-3969-e053-3a05fe0a2c94
|
8
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Palladacyclopentadienyl complexes bearing purine-based N-heterocyclic carbenes: A new class of promising antiproliferative agents against human ovarian cancer, file e309ade3-9c36-3969-e053-3a05fe0a2c94
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8
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Bis(dimethylsulfoxide)carbonateplatinum(II), a new synthon for a low-impact, versatile synthetic route to anticancer Pt carboxylates, file e309ade3-ff68-3969-e053-3a05fe0a2c94
|
8
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Synthesis of new allyl palladium complexes bearing purine-based NHC ligands with antiproliferative and proapoptotic activities on human ovarian cancer cell lines, file e309ade3-cef2-3969-e053-3a05fe0a2c94
|
7
|
|
Design, synthesis and biological activity of a novel Rutin analogue with improved lipid soluble properties, file e309ade3-0f4f-3969-e053-3a05fe0a2c94
|
6
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|
Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis, file e309ade4-9951-3969-e053-3a05fe0a2c94
|
6
|
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A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs, file 8580432b-00cf-4c35-9b4d-8db5dc11d407
|
5
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|
Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines, file e309ade0-301b-3969-e053-3a05fe0a2c94
|
5
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Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β(0)-Thalassemia Families with High Fetal Hemoglobin Levels, file e309ade0-e064-3969-e053-3a05fe0a2c94
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5
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Phytochemical Analysis and Potential Natural Compounds Against SARS-CoV-2/COVID-19 in Essential Oils Derived From Medicinal Plants Originating From Lebanon. An Information Note, file e309ade4-c968-3969-e053-3a05fe0a2c94
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5
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|
Sirolimus-mediated induction of fetal hemoglobin in beta-thalassemia: impact of the XmnI rs74482144 polymophism, file e309ade5-1100-3969-e053-3a05fe0a2c94
|
5
|
|
Facile synthesis of 2-nitroalkanols by Tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones, file 83c7ed6a-46e6-4cdd-964c-990c45e7b6d5
|
4
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|
null, file e309ade0-22d5-3969-e053-3a05fe0a2c94
|
3
|
|
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222, file e309ade0-a9e5-3969-e053-3a05fe0a2c94
|
3
|
|
Phytochemical and pharmacological properties of essential oils from Cedrus species, file e309ade1-ab8a-3969-e053-3a05fe0a2c94
|
3
|
|
Exploring the effect of chirality on the therapeutic potential of N-alkyl-deoxyiminosugars: anti-inflammatory response to Pseudomonas aeruginosa infections for application in CF lung disease, file e309ade2-4e7a-3969-e053-3a05fe0a2c94
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3
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Sirolimus-mediated induction of fetal hemoglobin in beta-thalassemia: impact of the XmnI rs74482144 polymophism, file e309ade2-93b8-3969-e053-3a05fe0a2c94
|
3
|
|
A new amido-phosphine of dichloroacetic acid as an active ligand for metals of pharmaceutical interest. Synthesis, characterization and tests of antiproliferative and pro-apoptotic activity, file e309ade3-1819-3969-e053-3a05fe0a2c94
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3
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Polytopic carriers for platinum ions: from digalloyl depside to tannic acid, file e309ade4-c533-3969-e053-3a05fe0a2c94
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3
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A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1, file e309ade4-d2e9-3969-e053-3a05fe0a2c94
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3
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New TMA (4,6,4'-Trimethyl angelicin) Analogues as Anti-Inflammatory Agents in the Treatment of Cystic Fibrosis Lung Disease, file 2a875cf3-4552-447b-9ec1-76c7b553d7cc
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2
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Comparative antiproliferative activities of wood and seeds essential oils of Juniperus oxycedrus L. against K562 human chronic myelogenus leukemia cells., file e309ade0-48d9-3969-e053-3a05fe0a2c94
|
2
|
|
Phloridzin derivatives inhibiting pro-inflammatory cytokine expression in human cystic fibrosis IB3-1 cells, file e309ade0-9938-3969-e053-3a05fe0a2c94
|
2
|
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Antitumor effects of new synthetic isoxazole derivatives, file e309ade1-4d1b-3969-e053-3a05fe0a2c94
|
2
|
|
INVOLVEMEMENT OF GBA2 IN THE INFLAMMATORY RESPONSE TO PSEUDOMONAS AERUGINOSA IN CYSTIC FIBROSIS, file e309ade1-4fe2-3969-e053-3a05fe0a2c94
|
2
|
|
Phloridzin derivatives inhibiting proinflammatory cytokine expression in human cystic fibrosis IB3-1 cells, file e309ade1-56f2-3969-e053-3a05fe0a2c94
|
2
|
|
Synthesis of new allyl palladium complexes bearing purine-based NHC ligands with antiproliferative and proapoptotic activities on human ovarian cancer cell lines, file e309ade2-12aa-3969-e053-3a05fe0a2c94
|
2
|
|
Development of microRNA based protocols for detection of autologous blood transfusion in sport, file e309ade2-2388-3969-e053-3a05fe0a2c94
|
2
|
|
Bis(dimethylsulfoxide)carbonateplatinum(II), a new synthon for a low-impact, versatile synthetic route to anticancer Pt carboxylates, file e309ade3-1af2-3969-e053-3a05fe0a2c94
|
2
|
|
Palladacyclopentadienyl complexes bearing purine-based N-heterocyclic carbenes: A new class of promising antiproliferative agents against human ovarian cancer, file e309ade3-1b0f-3969-e053-3a05fe0a2c94
|
2
|
|
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles, file e309ade3-1b15-3969-e053-3a05fe0a2c94
|
2
|
|
Synthesis and characterization of Pt complexes containing dichloroacetate (DCA), designed for dual anticancer action, file e309ade3-2b3a-3969-e053-3a05fe0a2c94
|
2
|
|
A PNA-based masking strategy for CFTR upregulation by targeting miR-145-5p binding sites of CFTR mRNA, file e309ade4-e1d6-3969-e053-3a05fe0a2c94
|
2
|
|
Phytochemical and pharmacological properties of essential oils from Cedrus species, file e309ade4-eac7-3969-e053-3a05fe0a2c94
|
2
|
|
Analysis of the miRNome as a possible tool for the detection of autologous blood transfusion misuse in sport, file e309ade5-10fe-3969-e053-3a05fe0a2c94
|
2
|
|
Treatment of erythroid precursor cells from β‐thalassemia patients with cinchona alkaloids: Induction of fetal hemoglobin production, file e309ade5-17a9-3969-e053-3a05fe0a2c94
|
2
|
|
Improved Trimethylangelicin Analogs for Cystic Fibrosis: Design, Synthesis and Preliminary Screening, file 110a79a1-420d-4aac-895a-d86073581701
|
1
|
|
Multifunctional Profiling of Moringa oleifera Leaf Extracts for Topical Application: A Comparative Study of Different Collection Time, file 3f0f9c46-48cf-4afc-a262-1d5a2e9972b8
|
1
|
|
null, file 683c2234-4793-4b0a-9ccf-72e9fd6e3fb3
|
1
|
|
The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers, file 7068a5bc-c5f6-4b8f-a90d-1f6890160ff6
|
1
|
|
Bergamot (Citrus bergamia Risso) fruit extracts as gamma-globin gene expression inducers: Phyto-chemical and functional perspectives, file e309ade0-28fa-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-e2f0-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-e32f-3969-e053-3a05fe0a2c94
|
1
|
|
A validated THALAMOSS cellular biobank for β-thalassemia, file e309ade0-e331-3969-e053-3a05fe0a2c94
|
1
|
|
High levels of apoptosis induced in human glioma cell lines by combined treatment with antagomiR PNAs and pre-miRNA molecules, file e309ade0-e727-3969-e053-3a05fe0a2c94
|
1
|
|
Induction of apoptosis of human glioma cell lines: Effects of combined treatment with corilagin and temozolomide, file e309ade0-e728-3969-e053-3a05fe0a2c94
|
1
|
|
A Novel Frameshift Mutation (+A) at Codon 18 of the beta-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and deltabeta-Thalassemia, file e309ade0-e965-3969-e053-3a05fe0a2c94
|
1
|
|
Everolimus is a potent inducer of erythroid differentation and gamma-globin gene expression in human erythroid cells, file e309ade0-e9c8-3969-e053-3a05fe0a2c94
|
1
|
|
Effects on erythroid differentiation of platinum(II) complexes of synthetic bile acid derivatives, file e309ade0-e9ca-3969-e053-3a05fe0a2c94
|
1
|
|
Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs, file e309ade0-eac2-3969-e053-3a05fe0a2c94
|
1
|
|
Expression of miR-93 and IL-8 During Pseudomonas aeruginosa Mediated Induction of Pro-Inflammatory Responses, file e309ade0-eac4-3969-e053-3a05fe0a2c94
|
1
|
|
Virtual screening against nuclear factor kB (NF-kB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis, file e309ade0-eb28-3969-e053-3a05fe0a2c94
|
1
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Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives, file e309ade0-eb2e-3969-e053-3a05fe0a2c94
|
1
|
|
Effects of extracts from Bangladeshi medicinal plants on in vitro proliferation of human breast cancer cell lines and expression of estrogen receptor alpha gene, file e309ade0-ebec-3969-e053-3a05fe0a2c94
|
1
|
|
Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum, file e309ade0-ec29-3969-e053-3a05fe0a2c94
|
1
|
|
Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin, file e309ade0-ec2f-3969-e053-3a05fe0a2c94
|
1
|
|
Rapamycin-mediated induction of gamma-globin mRNA accumulation in human eryhtroid cells, file e309ade0-edd8-3969-e053-3a05fe0a2c94
|
1
|
|
Effects of vanadium complexes on cell growth of human leukemia cells and protein-DNA interactions, file e309ade0-edde-3969-e053-3a05fe0a2c94
|
1
|
|
Bangladeshi medicinal plant extracts inhibiting molecular interactions between nuclear factors and target DNA sequences mimicking NF-kappaB binding sites, file e309ade0-eeaa-3969-e053-3a05fe0a2c94
|
1
|
|
Inhibitory effects of medicinal plant extracts on interactions between DNA and transcription factors involved in inflammation, file e309ade0-eeac-3969-e053-3a05fe0a2c94
|
1
|
|
In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa, file e309ade0-eeb0-3969-e053-3a05fe0a2c94
|
1
|
|
Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen, file e309ade0-ef33-3969-e053-3a05fe0a2c94
|
1
|
| Totale |
2488 |