This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfuidic approach. The effect of different production parameters has been investigated for their effect on PM-MTH characteristics.
Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia
MAZZITELLI, Stefania;BROGNARA, Eleonora;LAMPRONTI, Ilaria;GAMBARI, Roberto;NASTRUZZI, Claudio
2012
Abstract
This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfuidic approach. The effect of different production parameters has been investigated for their effect on PM-MTH characteristics.File in questo prodotto:
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