In this review we summarize the structure and biological effects of linear and angular psoralens. These compounds exhibit interesting biological effects on the cell cycle, apoptosis and differentiation. These molecules should be considered promising drugs in the therapy of several diseases, including psoriasis, mycosis fungoides and cancer. Also, preclinical data demonstrate a possible use of these molecules for the treatment of beta-thalassemia and other hematological disorders.
Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives
BIANCHI, Nicoletta;ZUCCATO, Cristina;BORGATTI, Monica;LAMPRONTI, IlariaPenultimo
;GAMBARI, Roberto
Ultimo
2009
Abstract
In this review we summarize the structure and biological effects of linear and angular psoralens. These compounds exhibit interesting biological effects on the cell cycle, apoptosis and differentiation. These molecules should be considered promising drugs in the therapy of several diseases, including psoriasis, mycosis fungoides and cancer. Also, preclinical data demonstrate a possible use of these molecules for the treatment of beta-thalassemia and other hematological disorders.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Viola G et al Annals of the New York Academy of Sciences 2009.pdf
solo gestori archivio
Descrizione: Full text editoriale
Tipologia:
Full text (versione editoriale)
Licenza:
NON PUBBLICO - Accesso privato/ristretto
Dimensione
417.73 kB
Formato
Adobe PDF
|
417.73 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
