In this review we summarize the structure and biological effects of linear and angular psoralens. These compounds exhibit interesting biological effects on the cell cycle, apoptosis and differentiation. These molecules should be considered promising drugs in the therapy of several diseases, including psoriasis, mycosis fungoides and cancer. Also, preclinical data demonstrate a possible use of these molecules for the treatment of beta-thalassemia and other hematological disorders.

Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives

BIANCHI, Nicoletta;ZUCCATO, Cristina;BORGATTI, Monica;LAMPRONTI, Ilaria
Penultimo
;
GAMBARI, Roberto
Ultimo
2009

Abstract

In this review we summarize the structure and biological effects of linear and angular psoralens. These compounds exhibit interesting biological effects on the cell cycle, apoptosis and differentiation. These molecules should be considered promising drugs in the therapy of several diseases, including psoriasis, mycosis fungoides and cancer. Also, preclinical data demonstrate a possible use of these molecules for the treatment of beta-thalassemia and other hematological disorders.
Viola, G; Salvador, A; Vedaldi, D; Dall'Acqua, F; Bianchi, Nicoletta; Zuccato, Cristina; Borgatti, Monica; Lampronti, Ilaria; Gambari, Roberto
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1379117
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