VARANI, Katia
 Distribuzione geografica
Continente #
NA - Nord America 39.627
AS - Asia 19.693
EU - Europa 12.757
SA - Sud America 3.291
AF - Africa 305
OC - Oceania 28
Continente sconosciuto - Info sul continente non disponibili 26
AN - Antartide 1
Totale 75.728
Nazione #
US - Stati Uniti d'America 38.874
SG - Singapore 7.584
CN - Cina 6.020
DE - Germania 2.913
BR - Brasile 2.765
UA - Ucraina 2.367
IT - Italia 2.033
TR - Turchia 1.864
HK - Hong Kong 1.857
GB - Regno Unito 1.360
VN - Vietnam 1.174
FI - Finlandia 874
SE - Svezia 836
RU - Federazione Russa 721
PL - Polonia 495
FR - Francia 369
CA - Canada 360
MX - Messico 325
IN - India 228
AR - Argentina 207
ID - Indonesia 198
NL - Olanda 169
JP - Giappone 160
ZA - Sudafrica 148
BD - Bangladesh 140
BE - Belgio 122
ES - Italia 114
EC - Ecuador 90
IQ - Iraq 88
LT - Lituania 84
AT - Austria 70
CZ - Repubblica Ceca 66
CO - Colombia 52
VE - Venezuela 47
UZ - Uzbekistan 45
CL - Cile 41
PK - Pakistan 40
MA - Marocco 39
AE - Emirati Arabi Uniti 37
PY - Paraguay 34
SA - Arabia Saudita 31
KE - Kenya 29
JO - Giordania 26
IR - Iran 25
CH - Svizzera 24
IL - Israele 24
TN - Tunisia 24
UY - Uruguay 23
KR - Corea 21
AU - Australia 20
DZ - Algeria 18
EU - Europa 18
IE - Irlanda 18
PE - Perù 18
NP - Nepal 16
EG - Egitto 15
RO - Romania 15
AL - Albania 13
MY - Malesia 12
PT - Portogallo 12
LV - Lettonia 10
TW - Taiwan 10
BG - Bulgaria 9
BH - Bahrain 9
BO - Bolivia 9
DO - Repubblica Dominicana 9
HN - Honduras 9
JM - Giamaica 9
NO - Norvegia 9
TT - Trinidad e Tobago 9
BA - Bosnia-Erzegovina 8
SY - Repubblica araba siriana 8
AZ - Azerbaigian 7
KG - Kirghizistan 7
KZ - Kazakistan 7
LB - Libano 7
OM - Oman 7
AM - Armenia 6
CG - Congo 6
CI - Costa d'Avorio 6
CR - Costa Rica 6
HR - Croazia 6
MD - Moldavia 6
PS - Palestinian Territory 6
SN - Senegal 6
HU - Ungheria 5
MK - Macedonia 5
NZ - Nuova Zelanda 5
PA - Panama 5
PH - Filippine 5
XK - ???statistics.table.value.countryCode.XK??? 5
BY - Bielorussia 4
GE - Georgia 4
GR - Grecia 4
GT - Guatemala 4
GY - Guiana 4
NI - Nicaragua 4
RS - Serbia 4
TH - Thailandia 4
A2 - ???statistics.table.value.countryCode.A2??? 3
Totale 75.668
Città #
Singapore 4.475
Woodbridge 3.958
Ashburn 3.668
Fairfield 3.395
Jacksonville 2.606
Chandler 2.499
Houston 2.437
Ann Arbor 2.135
Beijing 1.905
Hong Kong 1.850
Santa Clara 1.815
Dallas 1.453
Wilmington 1.425
Seattle 1.353
Cambridge 1.109
Izmir 896
Nanjing 784
Los Angeles 693
Princeton 585
Munich 526
Ferrara 510
Boardman 475
Warsaw 457
New York 401
Ho Chi Minh City 384
Milan 341
Shanghai 314
San Diego 303
São Paulo 273
Nanchang 251
Shenyang 236
Hanoi 231
Mexico City 213
Turku 188
Tianjin 186
Helsinki 183
Dearborn 179
London 176
Hefei 173
Bremen 167
Changsha 157
Falkenstein 152
Hebei 148
Addison 140
Buffalo 140
Tokyo 140
Chicago 138
Jiaxing 138
Jakarta 137
The Dalles 133
Brooklyn 121
Frankfurt am Main 121
Montreal 121
Orem 119
Brussels 118
Denver 100
San Mateo 99
Moscow 95
Toronto 94
Jinan 93
Stockholm 92
Chennai 91
Zhengzhou 91
Falls Church 90
San Francisco 86
Norwalk 84
Johannesburg 82
Kunming 82
Dong Ket 81
Rio de Janeiro 79
Atlanta 78
Poplar 75
Phoenix 73
Boston 71
Mountain View 70
San Jose 70
Guangzhou 68
Manchester 67
Bologna 65
Council Bluffs 61
Ankara 60
Auburn Hills 59
Belo Horizonte 58
Düsseldorf 58
Orange 58
Haiphong 57
Ningbo 55
Amsterdam 51
Rome 51
Columbus 50
Philadelphia 50
Redwood City 49
Washington 45
Augusta 44
Porto Alegre 44
Brasília 43
Da Nang 41
Des Moines 39
Tashkent 39
Curitiba 38
Totale 50.257
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 1.174
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 349
Pharmacology of Adenosine Receptors: The State of the Art 300
1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors 292
Alterazioni dei recettori alfa(2) adrenergici delle piastrine umane nell'ipertensione essenziale 267
A glance at adenosine receptors: Novel target for antitumor therapy 266
Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455 257
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice 246
Psychostimulant effect of the synthetic cannabinoid JWH-018 and AKB48. Behavioural, neurochemical and Dopamine transporter scan imaging studies in mice 242
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 240
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 238
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 238
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 234
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 231
A1 and A3 adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes 230
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives as new potent and selective human A3 adenosine receptor antagonists. Molecular modeling studies and pharmacological evaluation 228
Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice 226
The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles 224
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts 223
Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fields 220
The A3 adenosine receptor: history and perspectives 219
Adenosine receptors and human melanoma 217
Pulsed Electromagnetic Field Exposure Reduces Hypoxia and Inflammation Damage in Neuron-Like and Microglial Cells 217
A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release 216
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 215
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 215
Repeated dosing with NCX1404, a nitric oxide-donating pregabalin, re-establishes normal nociceptive responses in mice with streptozotocin-induced painful diabetic neuropathy 215
Recettori e trasduzione del segnale 214
A(2B) adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway 214
Recettori e trasduzione del segnale 213
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 213
Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease 213
A(2A) adenosine receptors are up-regulated in lymphocytes from amyotrophic lateral sclerosis patients 210
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 209
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 206
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter 205
Adenosine receptor targeting in health and disease 204
Adenosine A1 receptors in the rat brain in the kindling model of epilepsy 202
“Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the Gender-Omics and Sex-Omics Era 202
Multiple sclerosis lymphocytes upregulate A(2A) adenosine receptors that are antiinflammatory when stimulated 201
Cannabinoid CB2 receptor attenuates morphine-induced inflammatory responses in activated microglial cells 201
Effect of low frequency electromagnetic fields on A2A adenosine receptors in human neutrophils. 200
The activation of μ-opioid receptor potentiates LPS-induced NF-kB promoting an inflammatory phenotype in microglia 200
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes. 199
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 198
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 198
Alteration of A3 adenosine receptors in human neutrophils and low frequency electromagnetic fields 197
Comparison of prazosin, terazosin and tamsulosin: Functional and binding studies in isolated prostatic and vascular human tissues 197
Adenosine modulates vascular endothelial growth factor expression via hypoxiainducible factor-1 in human glioblastoma cells. 196
Role and function of A2A and A3 adenosine receptors in patients with ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis 196
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 192
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects? 192
Adenosine signaling contributes to ethanol-induced fatty liver in mice 191
Biological activity of for-Met-Leu-Phe-OMe analogs: relevant substitutions specifically trigger killing mechanisms in human neutrophils 191
Binding thermodynamics and intrinsic activity of adenosine A1 receptor ligands 190
Ala scan analogues of HOE 140. Synthesis and biological activities 190
Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A2A Adenosine Receptor Inverse Agonists with Antinociceptive Activity 190
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 189
Current status of A1 adenosine receptor allosteric enhancers 189
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 188
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 188
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 187
Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension 186
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 186
van't Hoff Based Thermodynamics 186
A3 adenosine receptor activation inhibits cell proliferation via phosphatidylinositol 3-kinase/Akt-dependent inhibition of the extracellular signal-regulated kinase 1/2 phosphorylation in A375 human melanoma cells 184
P2X1 and P2X3 Purinergic Receptors Differentially Modulate the Inflammatory Response in Human Osteoarthritic Synovial Fibroblasts 184
Receptor binding thermodynamics as a tool for linking drug efficacy and affinity 184
[3H]-MRE 2029-F20, a novel selective antagonist radioligand, for the pharmacological and biochemical characterization of A2B receptors. 184
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 183
Receptor binding at two different temperatures to discriminate agonist and antagonist behaviour of adenosine A1 receptor ligands in rat brain 182
Properties of a novel chemotactic esapeptide, an analogue of the prototypical N-formylmethionyl peptide 182
HIF-1 neuroprotection through erythropoietin increase in hypoxia: a role for A1 adenosine receptors 182
ALTERATION OF ADENOSINE RECEPTORS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE 181
Design, Synthesis, and Pharmacological Characterization of Indol-3-ylacetamides, Indol-3-yloxoacetamides, and Indol-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse Agonists 181
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 181
Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies 181
Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors 181
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 180
Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells 180
The Anti-Tumor Effect of A(3) Adenosine Receptors Is Potentiated by Pulsed Electromagnetic Fields in Cultured Neural Cancer Cells 180
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 180
Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor 180
A3 Receptors are Overexpressed in Pleura from Mesothelioma Patients and Reduce Cell Growth via Akt/NF-kB Pathway. 179
Binding and signaling studies disclose a potential allosteric site for cannabidiol in cannabinoid CB2 receptors 179
4-Amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as new potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies 178
Pathological overproduction: the bad side of adenosine 178
Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors 178
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 177
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 177
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 177
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 177
An evaluation of fMLP pocket dimensions and features using formyltetrapeptides 177
Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E(2) and cytokine release in human osteoarthritic synovial fibroblasts 177
Electrophysiological basis for the enhanced cardiac arrhythmogenic effect of isoprenaline in aged spontaneously hypertensive rats 176
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 176
A(2A) adenosine receptors are differentially modulated by pharmacological treatments in rheumatoid arthritis patients and their stimulation ameliorates adjuvant-induced arthritis in rats 176
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 176
M3 muscarinic receptors in peripheral lung parenchima of patients with chronic obstructive pulmonary disease. 175
Binding thermodynamics at A1 and A2A adenosine receptors 175
Totale 21.240
Categoria #
all - tutte 343.679
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 7.652
Totale 351.331


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20214.224 0 0 0 0 0 711 276 826 165 951 888 407
2021/20225.145 126 552 340 225 245 210 232 269 193 432 731 1.590
2022/20235.734 592 432 176 795 954 821 269 458 700 46 296 195
2023/20242.851 289 377 142 83 316 343 136 209 57 72 77 750
2024/202512.275 311 354 946 618 1.431 1.133 460 739 1.729 1.390 1.711 1.453
2025/202619.799 3.432 1.629 3.585 4.462 4.967 1.724 0 0 0 0 0 0
Totale 76.447