SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

PINOTTI, Mirko
 Distribuzione geografica
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Continente #
NA - Nord America 20.819
EU - Europa 11.498
AS - Asia 11.369
SA - Sud America 1.642
Continente sconosciuto - Info sul continente non disponibili 513
AF - Africa 260
OC - Oceania 23
AN - Antartide 1
Totale 46.125
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Nazione #
US - Stati Uniti d'America 20.315
FI - Finlandia 6.027
SG - Singapore 4.215
CN - Cina 2.864
IT - Italia 1.334
VN - Vietnam 1.282
BR - Brasile 1.258
DE - Germania 1.093
HK - Hong Kong 840
UA - Ucraina 784
GB - Regno Unito 577
TR - Turchia 545
FR - Francia 370
BD - Bangladesh 328
JP - Giappone 307
PL - Polonia 302
CA - Canada 266
RU - Federazione Russa 257
IN - India 253
SE - Svezia 211
ID - Indonesia 201
MX - Messico 175
AR - Argentina 144
ZA - Sudafrica 101
NL - Olanda 94
IQ - Iraq 88
ES - Italia 83
BE - Belgio 82
EC - Ecuador 64
PK - Pakistan 59
UZ - Uzbekistan 51
CO - Colombia 49
VE - Venezuela 45
MY - Malesia 41
AT - Austria 38
CZ - Repubblica Ceca 37
KE - Kenya 32
SA - Arabia Saudita 30
MA - Marocco 29
LT - Lituania 28
CL - Cile 26
NO - Norvegia 25
PH - Filippine 25
CH - Svizzera 24
JO - Giordania 22
AE - Emirati Arabi Uniti 21
KR - Corea 21
IR - Iran 20
PT - Portogallo 20
AU - Australia 19
DZ - Algeria 19
IL - Israele 18
PY - Paraguay 17
PE - Perù 16
IE - Irlanda 15
AL - Albania 14
DK - Danimarca 14
ET - Etiopia 14
GE - Georgia 14
JM - Giamaica 14
RO - Romania 14
TH - Thailandia 14
TN - Tunisia 14
AZ - Azerbaigian 13
KZ - Kazakistan 13
NP - Nepal 13
CR - Costa Rica 12
BO - Bolivia 10
TW - Taiwan 10
KG - Kirghizistan 9
NG - Nigeria 9
UY - Uruguay 9
GR - Grecia 7
RS - Serbia 7
SN - Senegal 7
BG - Bulgaria 6
DO - Repubblica Dominicana 6
EG - Egitto 6
LB - Libano 6
PS - Palestinian Territory 6
BH - Bahrain 5
BY - Bielorussia 5
GT - Guatemala 5
OM - Oman 5
TT - Trinidad e Tobago 5
BA - Bosnia-Erzegovina 4
BW - Botswana 4
GA - Gabon 4
HN - Honduras 4
KH - Cambogia 4
KW - Kuwait 4
LA - Repubblica Popolare Democratica del Laos 4
LU - Lussemburgo 4
LV - Lettonia 4
MT - Malta 4
PA - Panama 4
SV - El Salvador 4
AF - Afghanistan, Repubblica islamica di 3
CG - Congo 3
EU - Europa 3
Totale 45.550
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Città #
Helsinki 5.818
Singapore 2.607
Ashburn 2.171
Fairfield 1.429
Woodbridge 1.423
San Jose 1.375
Dallas 1.320
Chandler 991
Santa Clara 983
Houston 968
Beijing 926
Jacksonville 815
Hong Kong 814
Ann Arbor 719
Seattle 618
Wilmington 559
Cambridge 474
Ho Chi Minh City 415
Ferrara 409
New York 402
Los Angeles 348
Hanoi 319
Munich 317
Izmir 309
Council Bluffs 298
Warsaw 288
Tokyo 286
Nanjing 256
Princeton 233
Lauterbourg 196
Milan 172
Shanghai 165
Boardman 163
Jakarta 150
São Paulo 138
San Diego 136
Orem 123
Dearborn 109
Mexico City 106
Bremen 105
Toronto 92
London 87
Montreal 86
Nanchang 84
The Dalles 78
Brooklyn 75
Brussels 74
Shenyang 73
Denver 72
Atlanta 70
Tianjin 70
Buffalo 69
Chicago 69
Chennai 60
Falls Church 60
Da Nang 57
Frankfurt am Main 57
Jiaxing 57
Johannesburg 56
Redwood City 54
Phoenix 53
Changsha 52
Hefei 51
Moscow 48
Poplar 48
Rome 47
Hebei 45
Rio de Janeiro 45
Tashkent 44
Bologna 43
Haiphong 43
Jinan 43
San Francisco 43
Stockholm 42
Guangzhou 41
Turku 39
Manchester 38
Baghdad 37
San Mateo 37
Amsterdam 36
Falkenstein 36
Mountain View 35
Belo Horizonte 33
Curitiba 33
Dong Ket 33
Norwalk 32
Nuremberg 32
Kunming 30
Des Moines 28
Mumbai 28
Paris 28
Washington 27
Ankara 26
Biên Hòa 26
Nairobi 25
Auburn Hills 24
Columbus 24
Naples 24
Ningbo 24
Philadelphia 24
Totale 32.300
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Nome #
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 2.866
A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients 2.057
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 2.051
Differential functional readthrough over homozygous nonsense mutations contributes to the bleeding phenotype in coagulation factor VII deficiency 308
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 306
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth 305
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 300
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 297
An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes 289
Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings 283
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 282
Tailored collagen binding of albumin-fused hyperactive coagulation factor IX dictates in vivo distribution and functional properties 273
Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts 272
A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates 265
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 263
VITAMIN K-INDUCED MODIFICATION OF COAGULATION PHENOTYPE IN VKORC1 HOMOZYGOUS DEFICIENCY 259
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 252
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 251
Transposon-mediated Generation of Cellular and Mouse Models of Splicing Mutations to Assess the Efficacy of snRNA-based Therapeutics 247
Attività sulla emostasi di alcune piante della medicina tradizionale indiana 245
Chronic sleep deprivation markedly reduces coagulation factor VII expression 244
Responsiveness of hemophilia B- causing non sense mutations to ribosome readthrough-inducing drugs strictly depends on the nucleotide and prrotein context 244
Factor XIII-A dynamics in acute myocardial infarction: a novel prognostic biomarker? 244
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 241
Membrane binding and anticoagulant properties of protein S natural variants 240
Cationic lipid nanosystems as carriers for nucleic acids 238
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 238
The carboxyl-terminal region is not essential for secreted and functional levels of coagulation factor X 237
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 234
Nuove strategie per la veicolazione di acidi nucleici: nanosistemi cationici a matrice lipidica 233
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 232
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity 231
Evidence for an overlapping role of clock and npas2 transcription factors in liver circadian oscillators 229
Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model 224
Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis 223
Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster 222
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 221
Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile 220
Mutation pattern in clinically asymptomatic coagulation factor VII deficiency 220
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics 220
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 219
Effective hemostasis during minor surgery in a case of hereditary combined deficiency of vitamin K-dependent clotting factors 218
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 216
Temporal variations of coagulation factor VII activity in mice are influenced by lighting regime 213
The factor V Glu1608Lys mutation is recurrent in familial thrombophilia 213
FXIII levels and genotypes in myocardial infarction: a potential novel prognostic biomarker? 213
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 213
Asymmetric processing of mutant factor X Arg386Cys reveals differences between intrinsic and extrinsic pathway activation 213
Molecular bases of type II protein S deficiency: the I203-D204 deletion in the EGF4 domain alters GLA domain function 211
Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition 211
The dominant-negative von Willebrand factor gene deletion p.P1127-C1948delinsR: Molecular mechanism and modulation 210
The carboxyl-terminal region is NOT essential for secreted and functional levels of coagulation factor X 209
Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene 204
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations 204
Molecular bases of CRM+ factor X deficiency: a frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glul02Lys) in the second EGF‐like domain 203
Ribosome readthrough accounts for secreted full-length factor IX in hemophilia B patients with nonsense mutations 203
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 203
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 203
Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients. 200
Cationic lipid nanosystems as carriers for nucleic acids 199
Factor VII mutant V154G models a zymogen-like form of factor VIIa 198
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 198
Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency 197
Circadian rhythms in mouse blood coagulation 195
Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency 195
Residual factor VII activity and different hemorrhagic phenotypes in CRM+ factor VII deficiencies (Gly331Ser and Gly283Ser) 195
Nanosistemi lipidici per la veicolazione di acidi nucleici 195
CRISPR activation on coagulation F7 or F8 promoters potentiate trascriptional activity in the normal and mutated gene context 195
Characterization of PAR-mediated signaling induced by activated coagulation factor X mutants 191
Molecular mechanisms of FVII deficiency: Expression of mutations clustered in the IVS7 donor splice site of factor VII gene 186
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 185
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency 185
Characterization of the intracellular signalling capacity of natural FXa mutants with reduced pro-coagulant activity 185
Modulation of factor VII levels by intron 7 polymorphisms: Population and in vitro studies 183
Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis 183
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 183
Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA 183
Characterization of anti-coagulant properties of prenylated coumarin ferulenol. 182
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 182
Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity 181
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 180
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 179
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 178
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 178
Association of the homozygous nonsense mutation R402X in coagulation factor VII with asymptomatic phenotype 178
Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors 177
Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII 176
Cationic nanostructured lipid carrier (NLC) and monoolein aqueous dispersions (MAD) as potential carriers for nucleic acids 175
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 175
Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma 174
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 173
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 172
Rescue of coagulation factor VII function by the U1+5A snRNA 171
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 171
Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease 169
Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity 169
FXIII Levels in Myocardial Infarction: a Potential Novel Prognostic Biomarker? 168
A next-generation rFVIIa fusion protein with enhanced half-life as a novel by-passing tool in hemophilia 168
Impaired prothrombinase activity of factor X Gly381 Asp results in severe familial CRM+ FX deficiency 167
Molecular genetics and biology of congenital hemorrhagic diseases 167
Totale 27.726
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Categoria #
all - tutte 186.069
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.282
Totale 187.351
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.248 137 262 114 73 113 104 112 106 80 187 185 775
2022/20232.359 261 184 73 301 409 315 135 179 276 15 128 83
2023/20241.269 110 140 79 45 79 210 50 77 36 48 40 355
2024/20255.698 175 117 507 179 696 710 172 233 886 585 781 657
2025/202622.734 1.530 905 1.944 2.153 2.378 1.073 1.986 921 6.992 1.668 760 424
2026/2027561 561 0 0 0 0 0 0 0 0 0 0 0
Totale 46.125