SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

PINOTTI, Mirko
 Distribuzione geografica
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Continente #
NA - Nord America 12.683
EU - Europa 3.623
AS - Asia 2.980
SA - Sud America 57
OC - Oceania 13
AF - Africa 9
Continente sconosciuto - Info sul continente non disponibili 5
Totale 19.370
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Nazione #
US - Stati Uniti d'America 12.627
CN - Cina 1.323
IT - Italia 943
SG - Singapore 837
UA - Ucraina 718
DE - Germania 682
TR - Turchia 475
GB - Regno Unito 318
FI - Finlandia 289
PL - Polonia 203
SE - Svezia 165
ID - Indonesia 133
BE - Belgio 78
BR - Brasile 52
CA - Canada 52
IN - India 45
FR - Francia 41
NL - Olanda 40
VN - Vietnam 33
CZ - Repubblica Ceca 32
HK - Hong Kong 32
RU - Federazione Russa 29
IR - Iran 17
JP - Giappone 17
AU - Australia 11
KR - Corea 11
NO - Norvegia 11
RO - Romania 11
CH - Svizzera 10
DK - Danimarca 10
IQ - Iraq 10
AT - Austria 9
GE - Georgia 9
PT - Portogallo 9
TW - Taiwan 8
LT - Lituania 6
IE - Irlanda 5
IL - Israele 5
ES - Italia 4
PK - Pakistan 4
EU - Europa 3
MX - Messico 3
TH - Thailandia 3
UZ - Uzbekistan 3
ZA - Sudafrica 3
AR - Argentina 2
AZ - Azerbaigian 2
BD - Bangladesh 2
KE - Kenya 2
KG - Kirghizistan 2
KZ - Kazakistan 2
LU - Lussemburgo 2
MY - Malesia 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
BG - Bulgaria 1
BO - Bolivia 1
BY - Bielorussia 1
CR - Costa Rica 1
EC - Ecuador 1
EE - Estonia 1
GR - Grecia 1
HR - Croazia 1
JO - Giordania 1
LK - Sri Lanka 1
LV - Lettonia 1
MA - Marocco 1
MT - Malta 1
PE - Perù 1
PH - Filippine 1
PS - Palestinian Territory 1
TN - Tunisia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 19.370
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Città #
Fairfield 1.429
Woodbridge 1.423
Chandler 991
Houston 915
Santa Clara 853
Jacksonville 812
Ann Arbor 719
Ashburn 694
Singapore 647
Seattle 598
Wilmington 555
Cambridge 474
Ferrara 367
Izmir 307
Nanjing 255
Princeton 232
Beijing 215
Warsaw 202
New York 159
Boardman 149
Shanghai 145
Helsinki 132
San Diego 132
Jakarta 131
Milan 128
Dearborn 109
Bremen 105
Munich 90
Nanchang 84
Brussels 71
Shenyang 71
Los Angeles 69
Falls Church 60
Jiaxing 57
Redwood City 54
Tianjin 48
Hebei 45
Changsha 44
Jinan 42
London 40
Toronto 40
San Mateo 37
Mountain View 35
Dong Ket 33
Bologna 30
Kunming 30
Norwalk 30
Falkenstein 29
Des Moines 28
Guangzhou 28
Auburn Hills 24
Ningbo 24
Brno 23
Zhengzhou 20
Padova 19
Hong Kong 18
Washington 18
Orange 17
Frankfurt am Main 16
Monmouth Junction 16
Nuremberg 15
Indiana 14
Naples 13
Rome 13
Augusta 12
Düsseldorf 12
Hangzhou 12
Leawood 12
Florence 11
Council Bluffs 10
Hefei 10
Ottawa 10
Philadelphia 10
Taizhou 10
Ferrara di Monte Baldo 9
Paris 9
Piemonte 9
Baghdad 8
Copenhagen 8
Mānsa 8
Oslo 8
São Paulo 8
Andover 7
Chicago 7
Fuzhou 7
Hounslow 7
Olomouc 7
Redmond 7
Verona 7
Addison 6
Rochester 6
Taipei 6
Clifton 5
Dublin 5
Espoo 5
Lanzhou 5
Tokyo 5
Trieste 5
Alexandria 4
Amsterdam 4
Totale 14.504
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Nome #
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 193
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 185
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 181
Differential functional readthrough over homozygous nonsense mutations contributes to the bleeding phenotype in coagulation factor VII deficiency 176
Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings 169
An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes 162
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 160
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 160
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 155
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth 155
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 154
VITAMIN K-INDUCED MODIFICATION OF COAGULATION PHENOTYPE IN VKORC1 HOMOZYGOUS DEFICIENCY 151
Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile 147
The carboxyl-terminal region is NOT essential for secreted and functional levels of coagulation factor X 147
Nuove strategie per la veicolazione di acidi nucleici: nanosistemi cationici a matrice lipidica 146
Transposon-mediated Generation of Cellular and Mouse Models of Splicing Mutations to Assess the Efficacy of snRNA-based Therapeutics 143
Chronic sleep deprivation markedly reduces coagulation factor VII expression 142
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations 140
Responsiveness of hemophilia B- causing non sense mutations to ribosome readthrough-inducing drugs strictly depends on the nucleotide and prrotein context 136
The dominant-negative von Willebrand factor gene deletion p.P1127-C1948delinsR: Molecular mechanism and modulation 134
Factor XIII-A dynamics in acute myocardial infarction: a novel prognostic biomarker? 134
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 133
A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates. 130
Cationic lipid nanosystems as carriers for nucleic acids 130
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 128
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 128
The carboxyl-terminal region is not essential for secreted and functional levels of coagulation factor X 126
Circadian rhythms in mouse blood coagulation 125
Effective hemostasis during minor surgery in a case of hereditary combined deficiency of vitamin K-dependent clotting factors 124
Asymmetric processing of mutant factor X Arg386Cys reveals differences between intrinsic and extrinsic pathway activation 124
Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency 123
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 122
Temporal variations of coagulation factor VII activity in mice are influenced by lighting regime 121
Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis 121
Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency 121
Ribosome readthrough accounts for secreted full-length factor IX in hemophilia B patients with nonsense mutations 121
Membrane binding and anticoagulant properties of protein S natural variants 120
Major differences in bleeding symptoms between factor VII deficiency and hemophilia B 119
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 119
Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster 118
Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII 118
Cationic lipid nanosystems as carriers for nucleic acids 118
Residual factor VII activity and different hemorrhagic phenotypes in CRM+ factor VII deficiencies (Gly331Ser and Gly283Ser) 117
Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease. 116
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity 116
Characterization of anti-coagulant properties of prenylated coumarin ferulenol. 114
Detection and characterization of polymorphic markers in the factor-VII gene. 114
Molecular bases of type II protein S deficiency: the I203-D204 deletion in the EGF4 domain alters GLA domain function 113
Mutation pattern in clinically asymptomatic coagulation factor VII deficiency 113
Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts 113
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 113
Factor VII mutant V154G models a zymogen-like form of factor VIIa 112
Attività sulla emostasi di alcune piante della medicina tradizionale indiana 112
Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis 112
Rescue of coagulation factor VII function by the U1+5A snRNA 112
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 111
Evidence for an overlapping role of clock and npas2 transcription factors in liver circadian oscillators 110
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 110
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 110
The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies 110
RNA-based therapeutic approaches for coagulation factor deficiencies 109
Nanosistemi lipidici per la veicolazione di acidi nucleici 108
Molecular bases of CRM+ factor X deficiency: a frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glul02Lys) in the second EGF‐like domain 107
Modulation of factor VII levels by intron 7 polymorphisms: Population and in vitro studies 107
Intracellular evaluation of ER targeting elucidates a mild form of inherited coagulation deficiency 107
Characterization of the intracellular signalling capacity of natural FXa mutants with reduced pro-coagulant activity 107
Polymorphic changes in the 5' flanking region of factor VII have a combined effect on promoter strength 106
Impaired prothrombinase activity of factor X Gly381 Asp results in severe familial CRM+ FX deficiency 106
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 106
Molecular mechanisms of FVII deficiency: expression of mutations clustered in the IVS7 donor splice site of factor VII gene. 105
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 104
Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients. 104
Modulation of factor V levels in plasma by polymorphisms in the C2 domain 104
Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model 104
FXIII levels and genotypes in myocardial infarction: a potential novel prognostic biomarker? 103
Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition 103
Promoter methylation in coagulation F7 gene influences plasma FVII concentrations and relates to coronary artery disease. 102
Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors 102
Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity 101
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 101
The factor V Glu1608Lys mutation is recurrent in familial thrombophilia 100
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 99
Management of Kidney Transplantation in a Factor VII-Deficient Patient: Case Report 99
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 98
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 98
Detection of two missense mutations and characterization of a repeat polymorphism in the factor VII gene (F7) 97
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency 96
Gentamicin induces sub-therapeutic levels of coagulation factor VII in patients with nonsense mutations 96
Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA 96
Contribution of factor VII genotype to activated FVII levels. Differences in genotype frequencies between northern and southern European populations. 95
Pharmacokinetic properties of recombinant FVIIa in inherited FVII deficiency account for a large volume of distribution at steady state and a prolonged pharmacodynamic effect 95
Protein S mRNA in patients with protein S deficiency. 94
null 94
Reduced activation of the Gla19Ala FX variant via the extrinsic coagulation pathway results in symptomatic CRMred FX deficiency 93
null 93
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 93
In-Frame Deletion of von Willebrand Factor Exons 26-34 (D3-A3 Domains) in Type II von Willebrand Disease. 92
Gene therapy-based prophylaxis to rescue the "prima ballerina" 91
Release of Tissue Factor-bearing microparticles by human dendritic cells induced by stimulation of membrane P2X7 receptors 90
null 87
Totale 11.879
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Categoria #
all - tutte 106.339
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 692
Totale 107.031
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.244 0 0 0 0 0 0 0 369 312 331 160 72
2020/20212.796 202 160 147 290 96 242 231 330 131 454 366 147
2021/20222.248 137 262 114 73 113 104 112 106 80 187 185 775
2022/20232.359 261 184 73 301 409 315 135 179 276 15 128 83
2023/20241.269 110 140 79 45 79 210 50 77 36 48 40 355
2024/20252.721 175 117 507 179 696 710 172 165 0 0 0 0
Totale 19.853