SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

PINOTTI, Mirko
 Distribuzione geografica
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Continente #
NA - Nord America 19.425
EU - Europa 11.249
AS - Asia 11.023
SA - Sud America 1.618
AF - Africa 257
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 7
AN - Antartide 1
Totale 43.600
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Nazione #
US - Stati Uniti d'America 19.010
FI - Finlandia 6.027
SG - Singapore 4.154
CN - Cina 2.804
VN - Vietnam 1.281
BR - Brasile 1.245
IT - Italia 1.138
DE - Germania 1.089
HK - Hong Kong 822
UA - Ucraina 782
GB - Regno Unito 567
TR - Turchia 544
FR - Francia 365
JP - Giappone 306
PL - Polonia 300
RU - Federazione Russa 257
IN - India 251
SE - Svezia 209
ID - Indonesia 201
CA - Canada 198
MX - Messico 173
AR - Argentina 142
BD - Bangladesh 130
ZA - Sudafrica 101
NL - Olanda 90
IQ - Iraq 88
BE - Belgio 81
ES - Italia 75
EC - Ecuador 61
PK - Pakistan 59
UZ - Uzbekistan 51
CO - Colombia 48
VE - Venezuela 42
MY - Malesia 40
AT - Austria 37
CZ - Repubblica Ceca 37
KE - Kenya 31
SA - Arabia Saudita 30
MA - Marocco 29
LT - Lituania 27
CL - Cile 25
NO - Norvegia 25
PH - Filippine 25
JO - Giordania 22
IR - Iran 20
KR - Corea 20
AE - Emirati Arabi Uniti 19
CH - Svizzera 19
PT - Portogallo 19
DZ - Algeria 18
IL - Israele 18
PY - Paraguay 17
AU - Australia 16
PE - Perù 16
AL - Albania 14
DK - Danimarca 14
ET - Etiopia 14
GE - Georgia 14
IE - Irlanda 14
RO - Romania 14
TH - Thailandia 14
AZ - Azerbaigian 13
KZ - Kazakistan 13
NP - Nepal 13
TN - Tunisia 13
CR - Costa Rica 12
BO - Bolivia 10
TW - Taiwan 10
KG - Kirghizistan 9
NG - Nigeria 9
UY - Uruguay 9
JM - Giamaica 8
GR - Grecia 7
RS - Serbia 7
SN - Senegal 7
EG - Egitto 6
LB - Libano 6
PS - Palestinian Territory 6
BG - Bulgaria 5
BH - Bahrain 5
BY - Bielorussia 5
DO - Repubblica Dominicana 5
OM - Oman 5
BW - Botswana 4
GA - Gabon 4
KH - Cambogia 4
KW - Kuwait 4
LA - Repubblica Popolare Democratica del Laos 4
LU - Lussemburgo 4
LV - Lettonia 4
PA - Panama 4
AF - Afghanistan, Repubblica islamica di 3
CG - Congo 3
EU - Europa 3
GT - Guatemala 3
HR - Croazia 3
LK - Sri Lanka 3
MN - Mongolia 3
MT - Malta 3
NI - Nicaragua 3
Totale 43.541
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Città #
Helsinki 5.818
Singapore 2.585
Ashburn 2.051
Fairfield 1.429
Woodbridge 1.423
Dallas 1.277
San Jose 1.116
Chandler 991
Houston 955
Santa Clara 935
Beijing 912
Jacksonville 815
Hong Kong 796
Ann Arbor 719
Seattle 614
Wilmington 557
Cambridge 474
Ho Chi Minh City 415
Ferrara 398
New York 328
Hanoi 318
Los Angeles 318
Munich 317
Izmir 309
Warsaw 288
Tokyo 286
Nanjing 256
Princeton 232
Council Bluffs 226
Lauterbourg 196
Boardman 162
Shanghai 161
Jakarta 150
Milan 150
San Diego 134
São Paulo 129
Orem 110
Dearborn 109
Bremen 105
Mexico City 105
Nanchang 84
London 81
The Dalles 77
Brussels 73
Shenyang 73
Montreal 72
Tianjin 70
Brooklyn 64
Toronto 64
Falls Church 60
Chennai 59
Chicago 57
Da Nang 57
Frankfurt am Main 57
Jiaxing 57
Buffalo 56
Johannesburg 56
Denver 55
Atlanta 54
Redwood City 54
Changsha 52
Hefei 51
Moscow 48
Poplar 48
Hebei 45
Rio de Janeiro 45
Tashkent 44
Haiphong 43
Jinan 43
Stockholm 41
Guangzhou 40
Phoenix 39
Turku 39
Manchester 38
Baghdad 37
Bologna 37
San Mateo 37
Amsterdam 36
Falkenstein 36
Mountain View 35
Belo Horizonte 33
Dong Ket 33
Curitiba 32
Nuremberg 32
Kunming 30
Norwalk 30
Rome 29
Des Moines 28
Mumbai 28
Paris 28
San Francisco 28
Ankara 26
Biên Hòa 26
Nairobi 25
Auburn Hills 24
Ningbo 24
Zhengzhou 24
Brno 23
Columbus 23
Campinas 22
Totale 31.331
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Nome #
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 2.854
A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients 2.050
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 2.041
Differential functional readthrough over homozygous nonsense mutations contributes to the bleeding phenotype in coagulation factor VII deficiency 297
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 295
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth 295
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 292
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 289
An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes 284
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 275
Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings 272
A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates 256
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 249
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 244
VITAMIN K-INDUCED MODIFICATION OF COAGULATION PHENOTYPE IN VKORC1 HOMOZYGOUS DEFICIENCY 241
Transposon-mediated Generation of Cellular and Mouse Models of Splicing Mutations to Assess the Efficacy of snRNA-based Therapeutics 241
Responsiveness of hemophilia B- causing non sense mutations to ribosome readthrough-inducing drugs strictly depends on the nucleotide and prrotein context 239
Attività sulla emostasi di alcune piante della medicina tradizionale indiana 237
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 237
Chronic sleep deprivation markedly reduces coagulation factor VII expression 236
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 235
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 233
Factor XIII-A dynamics in acute myocardial infarction: a novel prognostic biomarker? 233
Nuove strategie per la veicolazione di acidi nucleici: nanosistemi cationici a matrice lipidica 230
Membrane binding and anticoagulant properties of protein S natural variants 229
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 228
Cationic lipid nanosystems as carriers for nucleic acids 228
Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts 226
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 226
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity 223
Evidence for an overlapping role of clock and npas2 transcription factors in liver circadian oscillators 220
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 217
The carboxyl-terminal region is not essential for secreted and functional levels of coagulation factor X 217
Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster 214
Mutation pattern in clinically asymptomatic coagulation factor VII deficiency 211
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 210
Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model 210
Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis 208
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 208
Effective hemostasis during minor surgery in a case of hereditary combined deficiency of vitamin K-dependent clotting factors 206
FXIII levels and genotypes in myocardial infarction: a potential novel prognostic biomarker? 205
Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile 203
Molecular bases of type II protein S deficiency: the I203-D204 deletion in the EGF4 domain alters GLA domain function 202
The carboxyl-terminal region is NOT essential for secreted and functional levels of coagulation factor X 202
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations 202
Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition 202
The dominant-negative von Willebrand factor gene deletion p.P1127-C1948delinsR: Molecular mechanism and modulation 200
The factor V Glu1608Lys mutation is recurrent in familial thrombophilia 197
Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene 197
Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients. 196
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics 196
Ribosome readthrough accounts for secreted full-length factor IX in hemophilia B patients with nonsense mutations 195
Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency 195
Asymmetric processing of mutant factor X Arg386Cys reveals differences between intrinsic and extrinsic pathway activation 195
Molecular bases of CRM+ factor X deficiency: a frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glul02Lys) in the second EGF‐like domain 194
Cationic lipid nanosystems as carriers for nucleic acids 194
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 193
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 192
Residual factor VII activity and different hemorrhagic phenotypes in CRM+ factor VII deficiencies (Gly331Ser and Gly283Ser) 191
Circadian rhythms in mouse blood coagulation 190
Temporal variations of coagulation factor VII activity in mice are influenced by lighting regime 188
Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency 187
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 186
Factor VII mutant V154G models a zymogen-like form of factor VIIa 183
Modulation of factor VII levels by intron 7 polymorphisms: Population and in vitro studies 182
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 182
Characterization of the intracellular signalling capacity of natural FXa mutants with reduced pro-coagulant activity 181
Molecular mechanisms of FVII deficiency: Expression of mutations clustered in the IVS7 donor splice site of factor VII gene 180
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 180
Nanosistemi lipidici per la veicolazione di acidi nucleici 179
Characterization of anti-coagulant properties of prenylated coumarin ferulenol. 177
Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity 177
Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis 177
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 177
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency 177
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 177
CRISPR activation on coagulation F7 or F8 promoters potentiate trascriptional activity in the normal and mutated gene context 174
Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA 174
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 174
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 174
Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII 173
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 172
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 172
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 172
Association of the homozygous nonsense mutation R402X in coagulation factor VII with asymptomatic phenotype 172
Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma 169
Cationic nanostructured lipid carrier (NLC) and monoolein aqueous dispersions (MAD) as potential carriers for nucleic acids 169
Rescue of coagulation factor VII function by the U1+5A snRNA 169
Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors 169
Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease 165
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 165
Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity 163
Detection and characterization of polymorphic markers in the factor-VII gene. 162
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 162
Contribution of factor VII genotype to activated FVII levels: Differences in genotype frequencies between northern and southern European populations 161
Characterization of PAR-mediated signaling induced by activated coagulation factor X mutants 161
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 161
A next-generation rFVIIa fusion protein with enhanced half-life as a novel by-passing tool in hemophilia 161
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 161
Molecular genetics and biology of congenital hemorrhagic diseases 160
Totale 26.682
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Categoria #
all - tutte 170.622
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.174
Totale 171.796
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021967 0 0 0 0 0 0 0 0 0 454 366 147
2021/20222.248 137 262 114 73 113 104 112 106 80 187 185 775
2022/20232.359 261 184 73 301 409 315 135 179 276 15 128 83
2023/20241.269 110 140 79 45 79 210 50 77 36 48 40 355
2024/20255.698 175 117 507 179 696 710 172 233 886 585 781 657
2025/202621.273 1.530 905 1.944 2.153 2.378 1.073 1.986 921 6.992 1.391 0 0
Totale 44.103