SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

PINOTTI, Mirko
 Distribuzione geografica
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Continente #
NA - Nord America 22.302
EU - Europa 11.623
AS - Asia 11.450
SA - Sud America 1.675
Continente sconosciuto - Info sul continente non disponibili 518
AF - Africa 261
OC - Oceania 24
AN - Antartide 1
Totale 47.854
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Nazione #
US - Stati Uniti d'America 21.723
FI - Finlandia 6.027
SG - Singapore 4.228
CN - Cina 2.882
IT - Italia 1.407
VN - Vietnam 1.289
BR - Brasile 1.273
DE - Germania 1.094
HK - Hong Kong 852
UA - Ucraina 784
GB - Regno Unito 585
TR - Turchia 546
FR - Francia 371
BD - Bangladesh 338
JP - Giappone 307
PL - Polonia 302
CA - Canada 301
IN - India 258
RU - Federazione Russa 257
SE - Svezia 245
ID - Indonesia 205
MX - Messico 177
AR - Argentina 147
ZA - Sudafrica 101
NL - Olanda 97
IQ - Iraq 88
ES - Italia 85
BE - Belgio 82
EC - Ecuador 67
PK - Pakistan 59
CO - Colombia 57
UZ - Uzbekistan 51
VE - Venezuela 49
MY - Malesia 44
AT - Austria 38
CZ - Repubblica Ceca 37
KE - Kenya 33
SA - Arabia Saudita 32
MA - Marocco 29
PH - Filippine 29
LT - Lituania 28
CL - Cile 26
NO - Norvegia 25
CH - Svizzera 24
JM - Giamaica 24
JO - Giordania 22
KR - Corea 22
AE - Emirati Arabi Uniti 21
AU - Australia 20
IR - Iran 20
PT - Portogallo 20
DZ - Algeria 19
CR - Costa Rica 18
IL - Israele 18
PY - Paraguay 17
PE - Perù 16
AL - Albania 15
IE - Irlanda 15
DK - Danimarca 14
ET - Etiopia 14
GE - Georgia 14
RO - Romania 14
TH - Thailandia 14
TN - Tunisia 14
AZ - Azerbaigian 13
KZ - Kazakistan 13
NP - Nepal 13
BO - Bolivia 10
SV - El Salvador 10
TW - Taiwan 10
KG - Kirghizistan 9
NG - Nigeria 9
UY - Uruguay 9
GT - Guatemala 8
HN - Honduras 8
TT - Trinidad e Tobago 8
BG - Bulgaria 7
GR - Grecia 7
RS - Serbia 7
SN - Senegal 7
DO - Repubblica Dominicana 6
EG - Egitto 6
LB - Libano 6
PS - Palestinian Territory 6
BH - Bahrain 5
BY - Bielorussia 5
NI - Nicaragua 5
OM - Oman 5
BA - Bosnia-Erzegovina 4
BW - Botswana 4
GA - Gabon 4
HR - Croazia 4
KH - Cambogia 4
KW - Kuwait 4
LA - Repubblica Popolare Democratica del Laos 4
LU - Lussemburgo 4
LV - Lettonia 4
MT - Malta 4
PA - Panama 4
AF - Afghanistan, Repubblica islamica di 3
Totale 47.269
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Città #
Helsinki 5.818
Singapore 2.612
Ashburn 2.274
San Jose 1.653
Fairfield 1.431
Woodbridge 1.423
Dallas 1.335
Santa Clara 1.034
Chandler 991
Houston 971
Beijing 942
Hong Kong 825
Jacksonville 815
Ann Arbor 719
Council Bluffs 688
Seattle 620
Wilmington 559
Cambridge 475
Ho Chi Minh City 417
Ferrara 414
New York 409
Los Angeles 366
Hanoi 323
Munich 317
Izmir 309
Warsaw 288
Tokyo 286
Nanjing 256
Princeton 233
Lauterbourg 196
Milan 192
Boardman 166
Shanghai 165
Jakarta 150
São Paulo 139
San Diego 138
Orem 123
Dearborn 109
Mexico City 107
Toronto 107
Bremen 105
Montreal 90
London 89
Chicago 85
Nanchang 84
Phoenix 84
The Dalles 78
Brooklyn 77
Brussels 74
Buffalo 73
Denver 73
Shenyang 73
Atlanta 71
Tianjin 70
Chennai 60
Falls Church 60
Da Nang 57
Frankfurt am Main 57
Jiaxing 57
Johannesburg 56
Redwood City 54
Rome 54
Changsha 52
Hefei 51
San Francisco 49
Moscow 48
Poplar 48
Hebei 45
Rio de Janeiro 45
Bologna 44
Tashkent 44
Haiphong 43
Jinan 43
Stockholm 42
Guangzhou 41
Turku 39
Manchester 38
Baghdad 37
San Mateo 37
Amsterdam 36
Falkenstein 36
Mountain View 35
Belo Horizonte 33
Curitiba 33
Dong Ket 33
Norwalk 33
Nuremberg 32
Kunming 30
Des Moines 29
Mumbai 28
Paris 28
Philadelphia 28
Washington 28
Ankara 26
Biên Hòa 26
Columbus 26
Naples 26
Boston 25
Charlotte 25
Florence 25
Totale 33.343
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Nome #
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 2.879
A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients 2.066
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 2.061
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth 318
Differential functional readthrough over homozygous nonsense mutations contributes to the bleeding phenotype in coagulation factor VII deficiency 314
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 313
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 309
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 307
An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes 297
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 290
Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings 289
Tailored collagen binding of albumin-fused hyperactive coagulation factor IX dictates in vivo distribution and functional properties 284
Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts 281
A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates 270
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 270
VITAMIN K-INDUCED MODIFICATION OF COAGULATION PHENOTYPE IN VKORC1 HOMOZYGOUS DEFICIENCY 264
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 260
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 258
Responsiveness of hemophilia B- causing non sense mutations to ribosome readthrough-inducing drugs strictly depends on the nucleotide and prrotein context 255
Factor XIII-A dynamics in acute myocardial infarction: a novel prognostic biomarker? 253
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 250
Attività sulla emostasi di alcune piante della medicina tradizionale indiana 249
Chronic sleep deprivation markedly reduces coagulation factor VII expression 249
Transposon-mediated Generation of Cellular and Mouse Models of Splicing Mutations to Assess the Efficacy of snRNA-based Therapeutics 249
The carboxyl-terminal region is not essential for secreted and functional levels of coagulation factor X 248
Cationic lipid nanosystems as carriers for nucleic acids 248
Membrane binding and anticoagulant properties of protein S natural variants 247
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 244
Nuove strategie per la veicolazione di acidi nucleici: nanosistemi cationici a matrice lipidica 242
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 242
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity 240
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 240
Evidence for an overlapping role of clock and npas2 transcription factors in liver circadian oscillators 234
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 231
Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis 229
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 229
Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster 228
Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model 228
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics 227
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 225
Mutation pattern in clinically asymptomatic coagulation factor VII deficiency 225
Effective hemostasis during minor surgery in a case of hereditary combined deficiency of vitamin K-dependent clotting factors 224
Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile 224
FXIII levels and genotypes in myocardial infarction: a potential novel prognostic biomarker? 221
Temporal variations of coagulation factor VII activity in mice are influenced by lighting regime 219
The factor V Glu1608Lys mutation is recurrent in familial thrombophilia 219
The dominant-negative von Willebrand factor gene deletion p.P1127-C1948delinsR: Molecular mechanism and modulation 219
Molecular bases of type II protein S deficiency: the I203-D204 deletion in the EGF4 domain alters GLA domain function 218
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 218
Asymmetric processing of mutant factor X Arg386Cys reveals differences between intrinsic and extrinsic pathway activation 218
Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition 217
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 215
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 215
The carboxyl-terminal region is NOT essential for secreted and functional levels of coagulation factor X 214
Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene 213
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 213
Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients. 212
Ribosome readthrough accounts for secreted full-length factor IX in hemophilia B patients with nonsense mutations 211
Molecular bases of CRM+ factor X deficiency: a frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glul02Lys) in the second EGF‐like domain 210
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations 210
Factor VII mutant V154G models a zymogen-like form of factor VIIa 207
Residual factor VII activity and different hemorrhagic phenotypes in CRM+ factor VII deficiencies (Gly331Ser and Gly283Ser) 205
Circadian rhythms in mouse blood coagulation 204
Characterization of PAR-mediated signaling induced by activated coagulation factor X mutants 204
Cationic lipid nanosystems as carriers for nucleic acids 204
Nanosistemi lipidici per la veicolazione di acidi nucleici 203
CRISPR activation on coagulation F7 or F8 promoters potentiate trascriptional activity in the normal and mutated gene context 203
Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency 201
Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency 201
Modulation of factor VII levels by intron 7 polymorphisms: Population and in vitro studies 192
Characterization of the intracellular signalling capacity of natural FXa mutants with reduced pro-coagulant activity 192
Molecular mechanisms of FVII deficiency: Expression of mutations clustered in the IVS7 donor splice site of factor VII gene 191
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 191
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 190
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 190
Characterization of anti-coagulant properties of prenylated coumarin ferulenol. 189
Cationic nanostructured lipid carrier (NLC) and monoolein aqueous dispersions (MAD) as potential carriers for nucleic acids 189
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 189
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency 189
Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA 189
Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity 188
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 188
Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis 186
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 186
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 186
Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors 186
Association of the homozygous nonsense mutation R402X in coagulation factor VII with asymptomatic phenotype 185
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 184
Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma 181
A next-generation rFVIIa fusion protein with enhanced half-life as a novel by-passing tool in hemophilia 181
Molecular genetics and biology of congenital hemorrhagic diseases 180
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 180
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 180
Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII 179
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 178
Rescue of coagulation factor VII function by the U1+5A snRNA 177
Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease 176
Design of a novel factor IX albumin fusion protein with enhanced coagulant activity and pharmacokinetic profile 175
FXIII Levels in Myocardial Infarction: a Potential Novel Prognostic Biomarker? 174
Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity 174
Totale 28.499
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Categoria #
all - tutte 196.426
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.367
Totale 197.793
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.849 0 0 114 73 113 104 112 106 80 187 185 775
2022/20232.359 261 184 73 301 409 315 135 179 276 15 128 83
2023/20241.269 110 140 79 45 79 210 50 77 36 48 40 355
2024/20255.698 175 117 507 179 696 710 172 233 886 585 781 657
2025/202622.734 1.530 905 1.944 2.153 2.378 1.073 1.986 921 6.992 1.668 760 424
2026/20272.290 591 897 802 0 0 0 0 0 0 0 0 0
Totale 47.854