SALVADORI, Severo
 Distribuzione geografica
Continente #
NA - Nord America 24.100
AS - Asia 11.501
EU - Europa 6.232
SA - Sud America 1.676
AF - Africa 242
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 12
Totale 43.783
Nazione #
US - Stati Uniti d'America 23.703
SG - Singapore 4.231
CN - Cina 3.070
UA - Ucraina 1.316
BR - Brasile 1.298
DE - Germania 1.298
VN - Vietnam 1.133
HK - Hong Kong 1.021
TR - Turchia 884
IT - Italia 790
GB - Regno Unito 789
FI - Finlandia 516
FR - Francia 407
SE - Svezia 359
RU - Federazione Russa 281
JP - Giappone 219
IN - India 205
BD - Bangladesh 182
CA - Canada 176
MX - Messico 169
AR - Argentina 122
PL - Polonia 114
ZA - Sudafrica 89
IQ - Iraq 79
BE - Belgio 78
ID - Indonesia 78
CO - Colombia 67
PK - Pakistan 63
NL - Olanda 62
EC - Ecuador 54
ES - Italia 51
UZ - Uzbekistan 47
PH - Filippine 44
VE - Venezuela 37
SA - Arabia Saudita 35
LT - Lituania 34
MA - Marocco 32
CL - Cile 30
TN - Tunisia 30
MY - Malesia 25
AT - Austria 24
AE - Emirati Arabi Uniti 23
PY - Paraguay 22
IR - Iran 21
KR - Corea 21
EG - Egitto 20
KE - Kenya 20
PE - Perù 18
CZ - Repubblica Ceca 17
JO - Giordania 17
UY - Uruguay 17
IL - Israele 16
DZ - Algeria 13
RO - Romania 13
AU - Australia 12
AL - Albania 11
CH - Svizzera 11
JM - Giamaica 11
NP - Nepal 11
BO - Bolivia 10
ET - Etiopia 9
LB - Libano 9
BH - Bahrain 8
HN - Honduras 8
AZ - Azerbaigian 7
IE - Irlanda 7
PA - Panama 7
TH - Thailandia 7
GR - Grecia 6
NZ - Nuova Zelanda 6
SN - Senegal 6
BG - Bulgaria 5
DO - Repubblica Dominicana 5
EU - Europa 5
HR - Croazia 5
KZ - Kazakistan 5
OM - Oman 5
QA - Qatar 5
DK - Danimarca 4
GT - Guatemala 4
HU - Ungheria 4
KG - Kirghizistan 4
PS - Palestinian Territory 4
PT - Portogallo 4
SV - El Salvador 4
TT - Trinidad e Tobago 4
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A2 - ???statistics.table.value.countryCode.A2??? 3
BJ - Benin 3
CI - Costa d'Avorio 3
CR - Costa Rica 3
LV - Lettonia 3
MM - Myanmar 3
MT - Malta 3
NG - Nigeria 3
NI - Nicaragua 3
NO - Norvegia 3
RS - Serbia 3
SK - Slovacchia (Repubblica Slovacca) 3
AM - Armenia 2
Totale 43.735
Città #
Singapore 2.683
Ashburn 2.436
Fairfield 2.364
Woodbridge 2.350
Houston 1.591
Jacksonville 1.434
San Jose 1.323
Ann Arbor 1.248
Chandler 1.102
Hong Kong 1.008
Beijing 970
Seattle 913
Santa Clara 911
Wilmington 847
Cambridge 789
Izmir 441
Nanjing 415
Ho Chi Minh City 372
Dallas 357
Los Angeles 318
Munich 310
New York 278
Princeton 276
Hanoi 258
San Diego 236
Lauterbourg 229
Tokyo 216
Boardman 196
Dearborn 196
Milan 193
Helsinki 169
Ferrara 154
São Paulo 128
Nanchang 122
Falkenstein 117
Shenyang 116
Hefei 110
Shanghai 105
Warsaw 104
Mexico City 102
Addison 89
London 83
Falls Church 81
Orem 78
Turku 78
San Mateo 76
Brooklyn 73
Brussels 73
Hebei 72
Tianjin 72
Auburn Hills 65
Bremen 63
Jiaxing 63
Jinan 63
Changsha 62
Chicago 60
Haiphong 57
Buffalo 55
Frankfurt am Main 55
Da Nang 51
Mountain View 49
The Dalles 48
Kunming 47
Montreal 47
Moscow 47
Atlanta 46
San Francisco 46
Toronto 46
Denver 45
Johannesburg 45
Stockholm 43
Washington 43
Redwood City 41
Tashkent 41
Chennai 40
Council Bluffs 40
Philadelphia 39
Phoenix 39
Rio de Janeiro 39
Zhengzhou 39
Poplar 38
Guangzhou 36
Norwalk 36
Ningbo 35
Belo Horizonte 33
Boston 33
Manchester 33
Bologna 30
Baghdad 29
Hải Dương 29
Columbus 28
Dhaka 26
Biên Hòa 25
Medellín 25
Jakarta 24
Mumbai 24
Tappahannock 24
Curitiba 23
Des Moines 22
Mcallen 22
Totale 30.301
Nome #
[Nphe(1),Arg(14),Lys(15)]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor 394
AGONISTI PIENI E PARZIALI ED ANTAGONISTI DEL RECETTORE PER NOCICETTINA/ORFANINA FQ AD ELEVATA POTENZA” 336
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 332
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 293
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ 290
A cyclic peptide T analogue with high chemotactic activity 287
A new selective antagonist of the nociceptin receptor 273
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor 272
[Dmt(1) ]N/OFQ(1-13)-NH(2) , a potent nociceptin/orphanin FQ and opioid receptor universal agonist. 269
In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor 263
Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior 259
A new ligand for the urotensin II receptor 254
[(t)Bu-d-Gly(5)]NPS, a pure and potent antagonist of the neuropeptide S receptor: In vitro and in vivo studies 251
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 247
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 242
2-Bromoamides as Synthons for Pseudopeptides Containing Aminodicarboxy Units 241
Cholinergic mediation in dermorphin-induced growth hormone secretion in man 241
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4′-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide 239
Dermorphin, a new opioid peptide, stimulates thyrotropin secretion in normal subjects 239
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 239
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 237
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist 235
[Nphe(1)]nociceptin-(1-13)-NH2 antagonizes nociceptin effects in the mouse colon 233
Address and message sequences for the nociceptin receptor: A structure-activity study of nociceptin-(1-13)-peptide amide 233
2-Aminoamides and Pseudopeptides Carrying an Amino Group Common to two Residues 233
Acid catalysis in the formation of dioxopiperazines from peptides containing tetrahydroisoquinoline‐3‐carboxylic acid at position 2 232
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2 230
Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test 230
Dermorphin inhibits spinal nociceptive flexion reflex in humans 229
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 224
Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay 223
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor 223
Dmt-Tic-NH-CH2-Bid (UFP-502), a potent DOP receptor agonist: In vitro and in vivo studies 220
UFP-112 a Potent and Long-Lasting Agonist Selective for the Nociceptin/Orphanin FQ Receptor 219
Physicochemical stability of cabazitaxel and docetaxel solutions 219
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist 217
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 215
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24 215
Pharmacological characterization of tachykinin tetrabranched derivatives 215
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis 213
Synthesis and biological activity of human neuropeptide S analogues modified in position 2 212
In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives 211
Peptide welding technology – A simple strategy for generating innovative ligands for G protein coupled receptors 210
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease 208
Further studies at neuropeptide S position 5: Discovery of novel neuropeptide S receptor antagonists 207
UFP-101 antagonizes the spinal antinociceptive effects of nociceptin/orphanin FQ; Behavioral and electrophysiological studies in mice 206
Neuropeptide S receptor ligands: a patent review (2005-2016) 205
Structure-activity study of the nociceptin(1-13)-NH2 N-terminal tetrapeptide and discovery of a nociceptin receptor antagonist 203
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. 202
Prolactin and growth hormone responses to dermorphin in patients with prolactin-secreting pituitary adenoma 202
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with C alpha,alpha-dialkylated amino acids 201
Characterization of [Nphe(1)]nociceptin(1-13)NH2, a new selective nociceptin receptor antagonist 200
Pharmacological characterization of nociceptin receptor: an in vitro study 200
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists 199
Urotensin II stimulates plasma extravasation in mice via UT receptor activation 199
Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic 198
DELTA-OPIOID RECEPTOR MODULATION OF THE HYPOTHALAMIC -PITUITARY-ADRENOCORTICAL AXIS 197
Nociceptin receptor activation inhibits tachykinergic non adrenergic non cholinergic contraction of guinea pig isolated bronchus 197
Crystal structures of dipeptides containing the Dmt-Tic pharmacophore 196
Prolactin-Releasing Activity of Dermorphin, a New Synthetic Potent Opiate-Like Peptide, in Normal Human Subjects 196
A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists 196
In vitro and in vivo pharmacological characterization of the neuropeptide S receptor antagonist [D-Cys(tBu)5]neuropeptide S 196
Opioid agonists and antagonists. Peptides containing N-terminal allyl groups and/or a thiomethylene linkage in place of a peptide bond 195
Structure-activity study at positions 3 and 4 of human neuropeptide S. 195
Neuropeptide S is a stimulatory anxiolytic agent: A behavioural study in mice 194
Critical role for prokineticin 2 in CNS autoimmunity 192
Dermorphin decreases plasma LH levels in human: Evidence for a modulatory role of gonadal steroids 191
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 190
ANALOGHI DERMASEPTINICI AD ATTIVITA’ ANTIMICROBICA 190
Stimulatory effect of dermorphin, a new synthetic potent opiate-like peptide, on human growth hormone secretion 189
Design of d-opioid peptide antagonists for emerging drug applications 187
Antidepressant-like effects of the nociceptin/orphanin FQ receptor antagonist UFP-101: New evidence from rats and mice 185
Characterization of nociceptin receptors in the periphery: in vitro and in vivo studies 184
Synthetic Approach to non-Isosteric Peptidomimetics Related to Human Endothelin 183
Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαqi5 183
Responses of plasma renin activity, aldosterone, adrenocorticotropin, and cortisol to dermorphin, a new synthetic potent opiate-like peptide, in man 182
Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model 181
Anxiolytic and antidepressant-like activities of UFP-512, a novel selective delta opiold receptor agonist 181
Synthesis and opioid activity of partial retro‐inverso analogs of dermorphin 180
Hydrogen sulfide induced disruption of Na+ homeostasis in the cortex 180
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11) 179
Structure–activity relationships of cyclic and linear peptide T analogues 179
Assessment of substitution in the second pharmacophore of Dmt-Tic analogues 179
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands 178
Pharmacology of [Tyr(1)]nociceptin analogs: receptor binding and bioassay studies 178
Nociceptin/orphanin FQ receptor ligands 177
Structure-activity relationship study on human urotensin II 176
6-N,N-dimethylamino-2,3-naphthalimide: A new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides 175
Somatostatin Inhibits the Dermorphin-Stimulated Thyrotropin Release in Man 173
The SH3 domain of nebulin binds selectively to type II peptides: theoretical prediction and experimental validation 173
Synthesis and biological activity of carboxyl terminally extended dermorphins 173
SUPRAMOLECULAR AGGREGATES COMPRISING MALEIMIDO CORES 172
In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen(5), DTrp(7), Dab(8)] urotensin II(4-11) (UFP-803) 172
Characterization of N,N(Me)(2)-Dmt-Tic-OH, a delta selective opioid dipeptide antagonist 171
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores 171
Pharmacological profile of hemokinin 1: a novel member of the tachykinin family 170
The nociceptin/orphanin FQ receptor antagonist, [Nphe(1)]NC(1-13)NH2, potentiates morphine analgesia 170
In vitro and in vivo pharmacological profile of UFP-512, a novel selective δ-opioid receptor agonist; correlations between desensitization and tolerance 170
Structure-activity relationships of nociceptin and related peptides: comparison with dynorphin A 169
Emerging Evidence for Neurotensin Receptor 1 Antagonists as Novel Pharmaceutics in Neurodegenerative Disorders. 169
Totale 21.233
Categoria #
all - tutte 192.494
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 3.333
Totale 195.827


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021171 0 0 0 0 0 0 0 0 0 0 0 171
2021/20222.994 126 290 230 211 230 135 136 170 114 228 224 900
2022/20232.733 297 96 90 335 463 380 148 272 388 16 143 105
2023/20241.291 150 183 94 32 103 233 51 82 17 22 32 292
2024/20255.005 141 106 410 141 637 458 156 346 682 512 749 667
2025/202614.741 1.509 666 1.429 2.046 2.032 995 1.674 739 1.380 1.686 505 80
Totale 44.043