SALVADORI, Severo
 Distribuzione geografica
Continente #
NA - Nord America 17.199
EU - Europa 3.922
AS - Asia 2.488
SA - Sud America 25
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 5
AF - Africa 1
Totale 23.648
Nazione #
US - Stati Uniti d'America 17.173
CN - Cina 1.593
UA - Ucraina 1.253
TR - Turchia 825
DE - Germania 773
GB - Regno Unito 566
IT - Italia 530
SE - Svezia 314
FI - Finlandia 281
BE - Belgio 58
FR - Francia 52
PL - Polonia 35
CA - Canada 26
IR - Iran 20
IN - India 18
RU - Federazione Russa 17
BR - Brasile 12
NL - Olanda 8
CO - Colombia 7
HK - Hong Kong 7
KR - Corea 7
RO - Romania 7
AT - Austria 5
CL - Cile 5
EU - Europa 5
A2 - ???statistics.table.value.countryCode.A2??? 3
CH - Svizzera 3
CZ - Repubblica Ceca 3
HR - Croazia 3
NZ - Nuova Zelanda 3
PH - Filippine 3
VN - Vietnam 3
AU - Australia 2
DK - Danimarca 2
GR - Grecia 2
IE - Irlanda 2
JP - Giappone 2
NO - Norvegia 2
NP - Nepal 2
UZ - Uzbekistan 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
HU - Ungheria 1
IQ - Iraq 1
IS - Islanda 1
KW - Kuwait 1
LU - Lussemburgo 1
MM - Myanmar 1
NG - Nigeria 1
PE - Perù 1
PT - Portogallo 1
TH - Thailandia 1
Totale 23.648
Città #
Fairfield 2.354
Woodbridge 2.335
Houston 1.563
Jacksonville 1.424
Ann Arbor 1.246
Ashburn 1.159
Chandler 1.099
Seattle 893
Wilmington 841
Cambridge 786
Izmir 436
Nanjing 410
Beijing 322
Princeton 275
San Diego 230
Dearborn 196
Boardman 181
Milan 164
Ferrara 141
Nanchang 118
Shenyang 116
Addison 89
New York 88
Falls Church 81
Shanghai 81
San Mateo 75
Hebei 71
Auburn Hills 65
Jiaxing 63
Bremen 62
Jinan 61
Changsha 58
Tianjin 56
Brussels 54
Mountain View 49
Kunming 47
Redwood City 41
Washington 38
Los Angeles 37
Philadelphia 37
Zhengzhou 37
Norwalk 35
Ningbo 34
Warsaw 34
London 31
Munich 30
Tappahannock 24
Helsinki 23
Des Moines 22
Mcallen 22
Guangzhou 21
Orange 21
Indiana 19
Montréal 17
Hefei 14
Taizhou 14
Augusta 13
Leawood 12
Redmond 12
Verona 12
Lanzhou 11
Ardabil 10
Düsseldorf 10
Bologna 9
Prescot 9
Hounslow 8
Kilburn 8
Medellín 7
Changchun 6
Chicago 6
Hangzhou 6
Hong Kong 6
Chiswick 5
Haikou 5
New Bedfont 5
Osasco 5
San Francisco 5
Walnut 5
Ferrara di Monte Baldo 4
Fuzhou 4
Yellow Springs 4
Florence 3
Innsbruck 3
Islington 3
La Canada Flintridge 3
Monmouth Junction 3
Mumbai 3
Portici 3
Rome 3
San Giorgio delle Pertiche 3
Toronto 3
Wandsworth 3
Zagreb 3
Acton 2
Antea 2
Auckland 2
Baotou 2
Bari 2
Bolzano 2
Bondeno 2
Totale 18.077
Nome #
AGONISTI PIENI E PARZIALI ED ANTAGONISTI DEL RECETTORE PER NOCICETTINA/ORFANINA FQ AD ELEVATA POTENZA” 186
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 159
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 159
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor 154
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ. 153
A CYCLIC PEPTIDE T ANALOGUE WITH HIGH CHEMOTACTIC ACTIVITY 146
Physicochemical stability of cabazitaxel and docetaxel solutions 146
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide. 142
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 140
Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic 136
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 136
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2 133
[Nphe(1),Arg(14),Lys(15)]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor 131
A new selective antagonist of the nociceptin receptor 130
null 130
Pharmacological characterization of nociceptin receptor: an in vitro study 130
Acid catalysis in the formation of dioxopiperazines from peptides containing tetrahydroisoquinoline‐3‐carboxylic acid at position 2 128
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor 128
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. 127
[Dmt(1) ]N/OFQ(1-13)-NH(2) , a potent nociceptin/orphanin FQ and opioid receptor universal agonist. 125
A new ligand for the urotensin II receptor 124
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 124
In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor 123
null 121
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist 121
Pharmacology of [Tyr(1)]nociceptin analogs: receptor binding and bioassay studies 121
UFP-112 a Potent and Long-Lasting Agonist Selective for the Nociceptin/Orphanin FQ Receptor 121
Synthesis and biological activity of human neuropeptide S analogues modified in position 2 120
Synthesis and opioid activity of partial retro‐inverso analogs of dermorphin 120
Dermorphin, a new opioid peptide, stimulates thyrotropin secretion in normal subjects 120
Opioid agonists and antagonists. Peptides containing N-terminal allyl groups and/or a thiomethylene linkage in place of a peptide bond 118
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 118
Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test 118
Stimulatory effect of dermorphin, a new synthetic potent opiate-like peptide, on human growth hormone secretion 117
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 117
2-Bromoamides as Synthons for Pseudopeptides Containing Aminodicarboxy Units 116
Structure-activity study of the nociceptin(1-13)-NH2 N-terminal tetrapeptide and discovery of a nociceptin receptor antagonist 115
[Nphe(1)]nociceptin-(1-13)-NH2 antagonizes nociceptin effects in the mouse colon 114
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11) 114
[(t)Bu-d-Gly(5)]NPS, a pure and potent antagonist of the neuropeptide S receptor: In vitro and in vivo studies 113
UFP-101 antagonizes the spinal antinociceptive effects of nociceptin/orphanin FQ; Behavioral and electrophysiological studies in mice 113
Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model 113
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores 112
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 112
Responses of plasma renin activity, aldosterone, adrenocorticotropin, and cortisol to dermorphin, a new synthetic potent opiate-like peptide, in man 111
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24. 111
Cholinergic mediation in dermorphin-induced growth hormone secretion in man 111
Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior 110
Synthesis and Pharmacological Activity of Partially Modified Retro-Inverso Dermorphin Tetrapeptides 110
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists. 110
Address and message sequences for the nociceptin receptor: A structure-activity study of nociceptin-(1-13)-peptide amide 110
null 110
Design of d-opioid peptide antagonists for emerging drug applications 110
Dmt-Tic-NH-CH2-Bid (UFP-502), a potent DOP receptor agonist: In vitro and in vivo studies 109
Role of benzimidazole (Bid) in the d-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH2-Bid (UFP-502) 108
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor. 107
Synthesis and antimicrobial activity of dermaseptin S1 analogues 107
Dermorphin inhibits spinal nociceptive flexion reflex in humans 107
The SH3 domain of nebulin binds selectively to type II peptides: theoretical prediction and experimental validation 107
Critical role for prokineticin 2 in CNS autoimmunity 107
Pharmacological characterization of tachykinin tetrabranched derivatives 107
Effect of dermorphin on behavior and hippocampal electrical activity in rabbits 106
Opioid diketopiperazines: Synthesis and activity of a prototypic class of opioid antagonists 106
Opioid receptor selectivity alteration by single residue replacement: Synthesis and activity profile of [Dmt]deltorphin B 106
Single Diastereomeric Desaminotyrosylalanyl Tetra- and Heptapeptides with Opioid Antagonistic Activity 106
Simultaneous targeting of multiple opioid receptors: a strategy to improve side-effect profile. 106
null 106
Symmetry-based inhibitors of HIV-1 protease. Design, synthesis and preliminary structure-activity studies of acylated 2,3-diamino-1-hydroxypropanes and 2,4 diamino-1-hydroxybutanes 106
Structure-activity relationships of cyclic and linear peptide T analogues. 106
Crystal structures of dipeptides containing the Dmt-Tic pharmacophore 106
Studies on the antinociceptive effect of [Nphe(1)]nociceptin(1-13)NH2 in mice 105
Characterization of nociceptin receptors in the periphery: in vitro and in vivo studies 105
Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay 105
Structure-activity study at positions 3 and 4 of human neuropeptide S. 105
Prolactin-Releasing Activity of Dermorphin, a New Synthetic Potent Opiate-Like Peptide, in Normal Human Subjects 105
2-Aminoamides and Pseudopeptides Carrying an Amino Group Common to two Residues 105
null 103
HIV-1 protease inhibitors containing an N-hydroxyamino acid core structure 103
Pharmacological profile of hemokinin 1: a novel member of the tachykinin family 102
Synthesis and biological activity of carboxyl terminally extended dermorphins. 102
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist 102
Urodynamic effects of intravesical nociceptin/orphanin FQ in neurogenic detrusor overactivity: A randomized, placebo-controlled, double-blind study 102
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease 102
Neuropeptide S receptor ligands: a patent review (2005-2016) 102
Prolactin and growth hormone responses to dermorphin in patients with prolactin-secreting pituitary adenoma 102
Structure-activity relationships of nociceptin and related peptides: comparison with dynorphin A 101
Opioid deltorphin C analogues containing cis- or trans-2- or 3- or 4-aminocyclohexanecarboxylic acid residues 101
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands 100
Synthetic Approach to non-Isosteric Peptidomimetics Related to Human Endothelin 100
Synthetic tetrapeptides related to dermorphin: Potent long lasting analgesic action following subcutaneous administration 100
UFP-101, a peptide antagonist selective for the nociceptin/orphanin FQ receptor 100
Synthesis and Opioid Activity of Dermorphin Tetrapeptides Bearing D-Methionine S-Oxide at Position 2 100
Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors 100
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis 100
null 99
The nociceptin/orphanin FQ receptor antagonist, [Nphe(1)]NC(1-13)NH2, potentiates morphine analgesia 99
Novel multiple opioid ligands based on 4-aminobenzazepinone (Aba), azepinoindole (Aia) and tetrahydroisoquinoline (Tic) scaffolds 99
Emerging Evidence for Neurotensin Receptor 1 Antagonists as Novel Pharmaceutics in Neurodegenerative Disorders. 99
Prokineticin Receptor 1 Antagonist PC-10 as a Biomarker for Imaging Inflammatory Pain 99
DOES hemopressin bind metal ions in vivo? 99
Totale 11.496
Categoria #
all - tutte 84.808
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.253
Totale 86.061


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.990 0 0 0 0 0 0 0 0 0 0 751 1.239
2019/20205.864 874 183 212 848 407 730 594 634 455 574 226 127
2020/20213.418 305 343 144 468 134 366 112 407 84 416 469 170
2021/20222.981 126 290 230 211 227 133 136 170 113 227 223 895
2022/20232.728 296 96 90 335 463 379 148 270 387 16 143 105
2023/2024979 150 181 94 32 103 233 51 82 17 22 14 0
Totale 23.907