SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

BALESTRA, Dario
 Distribuzione geografica
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Continente #
EU - Europa 5.866
NA - Nord America 5.743
AS - Asia 3.675
SA - Sud America 505
AF - Africa 111
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 15.906
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Nazione #
US - Stati Uniti d'America 5.583
FI - Finlandia 3.885
SG - Singapore 1.317
CN - Cina 876
IT - Italia 484
VN - Vietnam 441
DE - Germania 420
BR - Brasile 380
PL - Polonia 327
HK - Hong Kong 275
GB - Regno Unito 177
TR - Turchia 155
UA - Ucraina 149
FR - Francia 115
BD - Bangladesh 114
JP - Giappone 110
IN - India 90
ID - Indonesia 88
CA - Canada 83
RU - Federazione Russa 69
SE - Svezia 61
MX - Messico 60
AR - Argentina 52
ZA - Sudafrica 49
BE - Belgio 35
IQ - Iraq 31
ES - Italia 26
NL - Olanda 25
EC - Ecuador 22
PK - Pakistan 21
MY - Malesia 20
CO - Colombia 17
RO - Romania 15
CZ - Repubblica Ceca 14
KR - Corea 14
KE - Kenya 13
SA - Arabia Saudita 13
LT - Lituania 12
UZ - Uzbekistan 12
IR - Iran 11
AT - Austria 10
DZ - Algeria 10
JO - Giordania 10
CH - Svizzera 9
CL - Cile 9
MA - Marocco 9
PH - Filippine 8
TN - Tunisia 8
TW - Taiwan 8
VE - Venezuela 8
AE - Emirati Arabi Uniti 7
JM - Giamaica 7
NP - Nepal 7
PE - Perù 7
AZ - Azerbaigian 6
IL - Israele 6
KG - Kirghizistan 5
NO - Norvegia 5
PT - Portogallo 5
AL - Albania 4
CR - Costa Rica 4
EG - Egitto 4
KZ - Kazakistan 4
TH - Thailandia 4
AU - Australia 3
GE - Georgia 3
GR - Grecia 3
LB - Libano 3
NG - Nigeria 3
OM - Oman 3
PY - Paraguay 3
UY - Uruguay 3
BG - Bulgaria 2
BH - Bahrain 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GA - Gabon 2
GF - Guiana Francese 2
HR - Croazia 2
IE - Irlanda 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
NI - Nicaragua 2
RS - Serbia 2
SN - Senegal 2
SY - Repubblica araba siriana 2
XK - ???statistics.table.value.countryCode.XK??? 2
AF - Afghanistan, Repubblica islamica di 1
BJ - Benin 1
BW - Botswana 1
CG - Congo 1
CI - Costa d'Avorio 1
DK - Danimarca 1
EU - Europa 1
GH - Ghana 1
GI - Gibilterra 1
HN - Honduras 1
KW - Kuwait 1
LR - Liberia 1
Totale 15.893
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Città #
Helsinki 3.825
Singapore 792
Ashburn 670
San Jose 508
Fairfield 385
Woodbridge 324
Warsaw 320
Beijing 319
Chandler 309
Santa Clara 300
Hong Kong 262
Houston 231
Ann Arbor 218
Ferrara 188
Munich 169
Dallas 162
Ho Chi Minh City 154
Seattle 154
Jacksonville 145
Wilmington 134
Cambridge 126
Los Angeles 121
New York 120
Hanoi 96
Tokyo 96
Council Bluffs 95
Izmir 81
Jakarta 68
Bremen 64
Princeton 64
Nanjing 63
Lauterbourg 56
Milan 51
Boardman 44
Orem 40
São Paulo 39
Shanghai 38
Mexico City 37
Brussels 33
Atlanta 31
Dearborn 31
London 31
Toronto 29
Montreal 28
Rome 27
Brooklyn 26
Frankfurt am Main 26
Tianjin 25
Dong Ket 24
The Dalles 23
Johannesburg 22
Chennai 21
San Diego 21
Redwood City 20
Nanchang 19
Chicago 18
Moscow 18
Poplar 18
Buffalo 17
Da Nang 17
Denver 17
Rio de Janeiro 17
Stockholm 17
Turku 17
Shenyang 16
Baghdad 15
Manchester 15
Bologna 14
Changsha 14
Falkenstein 13
Mountain View 13
Nuremberg 13
Falls Church 12
Tashkent 12
Jiaxing 11
Kuala Lumpur 11
Mumbai 11
Nairobi 11
San Mateo 11
Hebei 10
Kunming 10
Paris 10
Phoenix 10
Shenzhen 10
Ankara 9
Biên Hòa 9
Brno 9
Haiphong 9
Norwalk 9
Amman 8
Boston 8
Curitiba 8
Fairford 8
Florence 8
Guangzhou 8
Lahore 8
Lappeenranta 8
Washington 8
Auburn Hills 7
Belo Horizonte 7
Totale 11.834
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Nome #
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 2.046
A fixed mutation in the respiratory complex I impairs mitochondrial bioenergetics in the endangered Apennine brown bear 1.913
C6orf10 low-frequency and rare variants in italian multiple sclerosis patients 348
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 301
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 299
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 294
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 279
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 260
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 248
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 247
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 237
Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies 234
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 233
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 229
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 220
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 216
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 212
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 203
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 201
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 197
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 195
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 184
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 181
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 180
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 178
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 177
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 177
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 177
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 175
Rescue of coagulation factor VII function by the U1+5A snRNA 170
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 169
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 167
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 166
Molecular genetics and biology of congenital hemorrhagic diseases 165
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 163
The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies 155
RNA-based therapeutic approaches for blood coagulation factor deficiencies caused by a splicing mutations 154
Dissection of pleiotropic effects of variants in and adjacent to F8 exon 19 and rescue of mRNA splicing and protein function 154
An advanced method for the small-scale production of high-quality minicircle DNA 149
OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spfash mice, and govern susceptibility to RNA-based therapies 148
Counteracting the Common Shwachman-Diamond Syndrome-Causing SBDS c.258+2T>C Mutation by RNA Therapeutics and Base/Prime Editing 146
Molecular mechanisms and determinants of innovative correction approaches in coagulation factor deficiencies 143
Contribution of asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms to full-length FVIII concentrate pharmacokinetics 142
The Asialoglycoprotein Receptor Minor Subunit Gene Contributes to Pharmacokinetics of Factor VIII Concentrates in Hemophilia A 142
Splicing Mutations Impairing CDKL5 Expression and Activity Can be Efficiently Rescued by U1snRNA-Based Therapy 137
Exon-Specific U1snRNA-Mediated Rescue of Splicing and Missense Changes in Hemophilia A 137
Rescue of coagulation factor VII mRNA processing and protein function by engineered U1+5A snRNA 134
MOLECULAR MECHANISMS AND THERAPEUTIC APROACHES FOR RESTORATION OF mRNA TRANSCRIPTION, MATURATION AND TRANSLATION IN INHERITED COAGULATION FACTOR DEFICIENCIES 129
“Compensatory” aberrant splicing supports residual expression levels in severe coagulation factor VII deficiency 124
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation Factor VII expression in mouse models 120
Deep molecular mechanisms of F8 exon 19 variants and translational approaches in Hemophilia A 118
Base and Prime editing of DNA as a new therapeutic option for Hemophilia A 115
RNA−based therapeutic approaches for blood coagulation factor deficiencies caused by splicing mutations 114
Prediction of inhibitor risk in haemophilia A using machine learning 107
La terapia genica nelle Malattie emorragiche e trombotiche 106
Restoration of coagulation factor IX function impaired by different splicing mutations by a unique exon-specific U1 small nuclear RNA (snRNA) 105
Whole-Exome Sequencing in a Family with an Unexplained Tendency for Venous Thromboembolism: Multicomponent Prediction of Low-Frequency Variant Deleteriousness and of Individual Protein Interaction 101
The asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms influence several parameters of full-length FVIII concentrate pharmacokinetics 101
An engineered U1 small nuclear RNA rescues splicing-defective coagulationF7gene expression in mice 100
F8 splicing-swithcing molecules for tailored hemophilia A therapies 96
Rescue of multiple Haemophilia A-causing mutations by a single ExSpeU1: the importance of the genomic context 96
Rescue of a FVIII splicing variant with engineered U1snRNAs 95
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation factor VII expression in mouse models 93
New Genome Editing Approaches: Base And Prime Editing To Revert Hemophilia A-Causing Point Mutations 90
Elucidation of aberrant SBDS splicing mechanisms to design RNA-therapeutics for Shwachman-Diamond Syndrome 90
Base and Prime Editors as new correction approaches for recurrent Hemophilia A Nonsense Mutations 87
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A 5’ SPLICE-SITE MUTATION CAUSING MUCOLIPIDOSIS TYPE III CAN BE EFFICIENTLY RESCUED BY U1 SNRNA-BASED THERAPY 81
null 79
Rescue of an F8 splicing variant (c.1752+5 G>C) with engineered U1snRNAs 78
Rescue of a panel of Hemophilia A-causing 5’ss splicing mutations by unique Exon-specific U1snRNA variants 78
Rescue of a hemophilia A-causing FVIII splicing variant via engineered U1SNRNAS 77
Reverting highly frequent f8 nonsense mutations: base and prime editing approach for hemophilia A 77
null 77
Rescue of a panel of splicing mutations causing hemophilia A by engineered U1snRNAs 73
null 73
null 71
RNA-Based therapeutics for OTC deficiency 59
Coexisting With Humans: Genomic and Behavioral Consequences in a Small and Isolated Bear Population 55
Novel Genetic Classification of Inhibitor Risk for F8 Nonsense Mutations Based on Immunogenic Profiling of Ribosomal Readthrough in EAHAD Database 55
DNA base editing corrects common hemophilia A mutations and restores factor VIII expression in in vitro and ex vivo models 54
Not Just Loss-of-Function Variations: Identification of a Hypermorphic Variant in a Patient With a CDKL5 Missense Substitution 54
null 51
RESCUE OF A PANEL OF SPLICING MUTATIONS CAUSING HEMOPHILIA A BY ENGINEERED U1-SNRNAS 50
La terapia genica nelle terapie emorragiche e trombotiche 46
null 42
Prime editing of the common Familial Dysautonomia-causing c.2204+6T>C splicing mutation 16
Molecular mechanisms and therapeutic strategies for the recurrent F9 (c.520 + 13 A > G) variant in hemophilia B 10
Totale 16.112
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Categoria #
all - tutte 58.466
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 860
Totale 59.326
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202147 0 0 0 0 0 0 0 0 0 0 0 47
2021/2022603 54 75 10 16 25 28 36 20 25 61 32 221
2022/2023734 80 70 20 100 138 81 52 51 76 9 40 17
2023/2024404 18 51 20 22 26 58 21 26 9 19 13 121
2024/20252.024 50 39 177 68 222 249 107 78 346 208 259 221
2025/20269.242 518 214 437 720 754 386 691 357 4.204 611 317 33
Totale 16.112