BOREA, Pier Andrea
 Distribuzione geografica
Continente #
NA - Nord America 53.214
AS - Asia 29.757
EU - Europa 20.298
SA - Sud America 4.471
AF - Africa 615
OC - Oceania 55
Continente sconosciuto - Info sul continente non disponibili 33
Totale 108.443
Nazione #
US - Stati Uniti d'America 52.063
SG - Singapore 10.621
CN - Cina 7.781
IT - Italia 3.815
DE - Germania 3.709
BR - Brasile 3.441
VN - Vietnam 3.188
FI - Finlandia 3.105
UA - Ucraina 3.090
HK - Hong Kong 2.492
TR - Turchia 2.383
GB - Regno Unito 1.731
SE - Svezia 1.147
FR - Francia 1.139
RU - Federazione Russa 922
JP - Giappone 644
BD - Bangladesh 627
IN - India 604
CA - Canada 538
PL - Polonia 469
MX - Messico 434
AR - Argentina 384
NL - Olanda 304
ZA - Sudafrica 236
ID - Indonesia 232
IQ - Iraq 195
ES - Italia 179
EC - Ecuador 158
CO - Colombia 148
BE - Belgio 144
PK - Pakistan 126
VE - Venezuela 108
UZ - Uzbekistan 98
LT - Lituania 94
SA - Arabia Saudita 87
MA - Marocco 84
CL - Cile 83
CZ - Repubblica Ceca 83
PH - Filippine 80
MY - Malesia 79
TN - Tunisia 78
AT - Austria 75
AE - Emirati Arabi Uniti 72
PY - Paraguay 63
KE - Kenya 50
JO - Giordania 45
AU - Australia 44
EG - Egitto 41
IR - Iran 40
IE - Irlanda 37
KR - Corea 37
IL - Israele 36
CR - Costa Rica 31
NP - Nepal 31
RO - Romania 30
DZ - Algeria 29
TW - Taiwan 28
UY - Uruguay 28
PE - Perù 27
JM - Giamaica 26
AZ - Azerbaigian 25
PT - Portogallo 25
BO - Bolivia 24
AL - Albania 23
CH - Svizzera 22
KZ - Kazakistan 22
EU - Europa 21
HN - Honduras 21
TH - Thailandia 21
ET - Etiopia 20
PS - Palestinian Territory 20
OM - Oman 18
BG - Bulgaria 17
LB - Libano 16
RS - Serbia 15
SN - Senegal 15
KG - Kirghizistan 14
BH - Bahrain 13
DO - Repubblica Dominicana 13
PA - Panama 13
QA - Qatar 13
SV - El Salvador 13
SY - Repubblica araba siriana 13
TT - Trinidad e Tobago 12
GR - Grecia 11
GT - Guatemala 11
HU - Ungheria 11
LV - Lettonia 11
MD - Moldavia 11
NO - Norvegia 11
BY - Bielorussia 10
HR - Croazia 10
NI - Nicaragua 10
AM - Armenia 9
BA - Bosnia-Erzegovina 9
NZ - Nuova Zelanda 9
AO - Angola 8
CI - Costa d'Avorio 8
KH - Cambogia 8
SK - Slovacchia (Repubblica Slovacca) 8
Totale 108.277
Città #
Singapore 6.940
Ashburn 5.291
Woodbridge 4.580
Fairfield 3.675
San Jose 3.379
Jacksonville 3.301
Chandler 2.910
Houston 2.898
Hong Kong 2.441
Ann Arbor 2.405
Helsinki 2.277
Santa Clara 2.262
Beijing 2.193
Wilmington 1.661
Dallas 1.558
Seattle 1.552
Cambridge 1.158
Izmir 1.123
Ho Chi Minh City 1.072
Nanjing 1.020
Los Angeles 867
Hanoi 773
Princeton 713
New York 627
Tokyo 623
Lauterbourg 559
Council Bluffs 553
Boardman 530
Munich 527
Milan 474
Ferrara 462
Warsaw 403
San Diego 351
São Paulo 327
Nanchang 323
Shanghai 319
Shenyang 306
Falkenstein 290
Mexico City 268
Hefei 243
Orem 230
Tianjin 221
London 208
Hebei 204
Dearborn 203
Turku 194
Changsha 189
Buffalo 188
Chicago 184
Bremen 183
Frankfurt am Main 176
San Mateo 176
Addison 170
Jiaxing 169
The Dalles 169
Da Nang 155
Montreal 151
Rome 149
Brooklyn 146
Toronto 146
Chennai 142
Brussels 138
Jinan 128
Haiphong 127
Denver 123
Amsterdam 117
Johannesburg 117
Jakarta 116
Falls Church 115
San Francisco 115
Rio de Janeiro 112
Zhengzhou 112
Atlanta 111
Phoenix 105
Manchester 102
Moscow 101
Kunming 99
Guangzhou 98
Norwalk 95
Auburn Hills 94
Philadelphia 90
Stockholm 90
Bologna 88
Tashkent 88
Florence 86
Mountain View 85
Baghdad 80
Ningbo 80
Boston 78
Poplar 78
Mumbai 73
Belo Horizonte 67
Ankara 64
Biên Hòa 63
Düsseldorf 63
Orange 63
Redwood City 63
Hải Dương 58
Quito 58
Verona 58
Totale 70.585
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.103
Farmacologia cellulare e molecolare, sistemi di trasmissione e autacoidi. Trasmissione purinergica 1.431
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 418
Pharmacology of Adenosine Receptors: The State of the Art 411
Progetto ex 60%- I recettori dell’adenosina come possibili “biomarkers” dei tumori colorettali. Studio su tessuti umani sani e tumorali e sulle cellule del sangue periferico. 401
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 333
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 324
Caffeine alters A(2A) adenosine receptors and their function in human platelets 321
A glance at adenosine receptors: Novel target for antitumor therapy 312
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 310
Alterazioni dei recettori alfa(2) adrenergici delle piastrine umane nell'ipertensione essenziale 306
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 303
Psychostimulant effect of the synthetic cannabinoid JWH-018 and AKB48. Behavioural, neurochemical and Dopamine transporter scan imaging studies in mice 302
Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455 290
The A3 adenosine receptor: history and perspectives 289
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 286
A(2B) adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway 286
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine (medazepam) 284
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 281
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives as new potent and selective human A3 adenosine receptor antagonists. Molecular modeling studies and pharmacological evaluation 276
Recettori e trasduzione del segnale 273
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects? 270
Pulsed Electromagnetic Field Exposure Reduces Hypoxia and Inflammation Damage in Neuron-Like and Microglial Cells 268
Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fields 263
Recettori e trasduzione del segnale 261
A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release 261
Human vascular kinin receptors of the B-2 type characterized by radioligand binding 261
Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease 259
Adenosine receptors and human melanoma 258
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts 256
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 254
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 251
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 251
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter 247
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 247
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 246
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 245
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 244
Effect of low frequency electromagnetic fields on A2A adenosine receptors in human neutrophils. 244
Role and function of A2A and A3 adenosine receptors in patients with ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis 244
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes. 244
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 241
Ala scan analogues of HOE 140. Synthesis and biological activities 240
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 238
Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies 238
A(2A) adenosine receptors are up-regulated in lymphocytes from amyotrophic lateral sclerosis patients 238
Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells 238
Alteration of A3 adenosine receptors in human neutrophils and low frequency electromagnetic fields 237
Multiple sclerosis lymphocytes upregulate A(2A) adenosine receptors that are antiinflammatory when stimulated 237
Comparison of prazosin, terazosin and tamsulosin: Functional and binding studies in isolated prostatic and vascular human tissues 236
Cannabinoid CB2 receptor attenuates morphine-induced inflammatory responses in activated microglial cells 236
Adenosine A1 receptors in the rat brain in the kindling model of epilepsy 236
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 231
Adenosine signaling contributes to ethanol-induced fatty liver in mice 230
Adenosine modulates vascular endothelial growth factor expression via hypoxiainducible factor-1 in human glioblastoma cells. 230
2 Aralkynyl and 2-heteroalkynyl derivatives of adenosine 5'-N-ethyluronamide as selective A2A adenosine receptor agonists 230
The activation of μ-opioid receptor potentiates LPS-induced NF-kB promoting an inflammatory phenotype in microglia 229
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 228
Adenosine receptors and cancer 227
7-nitro-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one (nitrazepam) 227
Octadecyl, phenyl and cyano phases comparison for the RP-HPLC prediction of octanol-water partition coefficient 226
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 226
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 226
HIF-1 neuroprotection through erythropoietin increase in hypoxia: a role for A1 adenosine receptors 226
Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A2A Adenosine Receptor Inverse Agonists with Antinociceptive Activity 225
A3 Receptors are Overexpressed in Pleura from Mesothelioma Patients and Reduce Cell Growth via Akt/NF-kB Pathway. 224
Adenosine receptor targeting in health and disease 224
Current status of A1 adenosine receptor allosteric enhancers 222
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 221
A concerted binding study using binding measurements, X-ray structural data and molecular modeling on the stereochemical features responsible for the affinity of 6-arylpyrrolo[2,1-d][1,5]benzothiazepines to mitochondrial benzodiazepine receptors 220
ALTERATION OF ADENOSINE RECEPTORS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE 220
A3 adenosine receptors are overexpressed in pleura from patients with mesothelioma and reduce malignant mesothelioma cell growth 220
4-(4-Fluorobenzoyl)-1-[2-(4-iodo-2,5-dimethoxyphenyl)ethyl]piperidine and its derivatives: Synthesis and affinity at 5-HT(2A), 5-HT(2B) and 5- HT(2C) serotonin receptors 220
Alteration of adenosine receptore in patients with chronic obstructive pulmonary disease 220
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 219
Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension 219
The Anti-Tumor Effect of A(3) Adenosine Receptors Is Potentiated by Pulsed Electromagnetic Fields in Cultured Neural Cancer Cells 219
van't Hoff Based Thermodynamics 219
Binding thermodynamics and intrinsic activity of adenosine A1 receptor ligands 218
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 218
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 218
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 217
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 217
Targeting A3 and A2A adenosine receptors in the fight against cancer 217
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 216
P2X1 and P2X3 Purinergic Receptors Differentially Modulate the Inflammatory Response in Human Osteoarthritic Synovial Fibroblasts 216
A2A adenosine receptor upregulation correlates with disease activity in patients with systemic lupus erythematosus 216
Pathological overproduction: the bad side of adenosine 216
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 215
[3H]-MRE 2029-F20, a novel selective antagonist radioligand, for the pharmacological and biochemical characterization of A2B receptors. 215
Binding and signaling studies disclose a potential allosteric site for cannabidiol in cannabinoid CB2 receptors 215
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 214
Agonists and antagonists: Molecular mechanisms and therapeutic applications 214
M3 muscarinic receptors in peripheral lung parenchima of patients with chronic obstructive pulmonary disease. 213
Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells 213
Receptor binding at two different temperatures to discriminate agonist and antagonist behaviour of adenosine A1 receptor ligands in rat brain 212
3H SCH 58261 labelling of functional A2A adenosine receptors in human neutrophil membranes 212
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 212
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 212
Electrophysiological basis for the enhanced cardiac arrhythmogenic effect of isoprenaline in aged spontaneously hypertensive rats 211
Totale 28.784
Categoria #
all - tutte 456.754
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 17.470
Totale 474.224


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20226.405 141 667 443 343 406 252 229 321 245 500 823 2.035
2022/20236.799 720 418 200 898 1.133 1.042 273 566 876 53 372 248
2023/20243.370 354 442 175 97 353 386 183 242 66 101 107 864
2024/202513.457 395 383 1.062 633 1.646 1.192 406 904 1.847 1.522 1.911 1.556
2025/202640.756 3.833 1.684 3.942 4.949 5.365 2.610 4.561 1.952 5.516 4.244 1.388 712
2026/20271.168 1.168 0 0 0 0 0 0 0 0 0 0 0
Totale 109.086