BOREA, Pier Andrea
 Distribuzione geografica
Continente #
NA - Nord America 56.428
AS - Asia 29.873
EU - Europa 20.537
SA - Sud America 4.495
Continente sconosciuto - Info sul continente non disponibili 676
AF - Africa 618
OC - Oceania 57
Totale 112.684
Nazione #
US - Stati Uniti d'America 55.140
SG - Singapore 10.650
CN - Cina 7.829
IT - Italia 3.962
DE - Germania 3.714
BR - Brasile 3.439
VN - Vietnam 3.184
FI - Finlandia 3.104
UA - Ucraina 3.086
HK - Hong Kong 2.500
TR - Turchia 2.381
GB - Regno Unito 1.739
SE - Svezia 1.221
FR - Francia 1.138
RU - Federazione Russa 921
JP - Giappone 643
BD - Bangladesh 636
IN - India 606
CA - Canada 597
PL - Polonia 469
MX - Messico 441
AR - Argentina 387
NL - Olanda 309
ID - Indonesia 237
ZA - Sudafrica 236
IQ - Iraq 195
ES - Italia 182
EC - Ecuador 164
CO - Colombia 157
BE - Belgio 144
PK - Pakistan 126
VE - Venezuela 112
UZ - Uzbekistan 98
LT - Lituania 94
SA - Arabia Saudita 92
MY - Malesia 86
CL - Cile 84
CZ - Repubblica Ceca 84
MA - Marocco 84
PH - Filippine 84
TN - Tunisia 78
AT - Austria 75
AE - Emirati Arabi Uniti 73
PY - Paraguay 63
JM - Giamaica 52
KE - Kenya 51
CR - Costa Rica 50
JO - Giordania 46
AU - Australia 45
EG - Egitto 41
IR - Iran 40
IE - Irlanda 38
KR - Corea 37
IL - Israele 36
NP - Nepal 32
DZ - Algeria 30
RO - Romania 30
HN - Honduras 29
UY - Uruguay 29
TW - Taiwan 28
PE - Perù 27
AZ - Azerbaigian 25
BO - Bolivia 25
PT - Portogallo 25
AL - Albania 23
KZ - Kazakistan 23
CH - Svizzera 22
EU - Europa 21
TH - Thailandia 21
ET - Etiopia 20
PS - Palestinian Territory 20
OM - Oman 18
TT - Trinidad e Tobago 18
BG - Bulgaria 17
LB - Libano 17
RS - Serbia 15
SN - Senegal 15
GT - Guatemala 14
KG - Kirghizistan 14
PA - Panama 14
SV - El Salvador 14
BH - Bahrain 13
DO - Repubblica Dominicana 13
QA - Qatar 13
SY - Repubblica araba siriana 13
GR - Grecia 12
HU - Ungheria 12
LV - Lettonia 11
MD - Moldavia 11
NI - Nicaragua 11
NO - Norvegia 11
AM - Armenia 10
BY - Bielorussia 10
HR - Croazia 10
NZ - Nuova Zelanda 10
BA - Bosnia-Erzegovina 9
AO - Angola 8
CG - Congo 8
CI - Costa d'Avorio 8
KH - Cambogia 8
Totale 111.867
Città #
Singapore 6.947
Ashburn 5.405
Woodbridge 4.579
San Jose 4.074
Fairfield 3.675
Jacksonville 3.300
Chandler 2.904
Houston 2.888
Hong Kong 2.449
Ann Arbor 2.404
Santa Clara 2.367
Helsinki 2.277
Beijing 2.237
Wilmington 1.661
Council Bluffs 1.623
Dallas 1.587
Seattle 1.559
Cambridge 1.157
Izmir 1.120
Ho Chi Minh City 1.070
Nanjing 1.019
Los Angeles 899
Hanoi 772
Princeton 713
New York 651
Tokyo 622
Lauterbourg 558
Boardman 529
Munich 527
Milan 502
Ferrara 462
Warsaw 403
San Diego 351
São Paulo 328
Nanchang 324
Shanghai 318
Shenyang 306
Falkenstein 290
Mexico City 272
Hefei 243
Orem 230
Tianjin 220
Chicago 213
London 209
Dearborn 203
Hebei 203
Turku 194
Buffalo 192
Changsha 189
Bremen 183
Frankfurt am Main 181
San Mateo 176
The Dalles 171
Addison 170
Toronto 170
Jiaxing 168
Rome 161
Montreal 155
Brooklyn 154
Da Nang 154
Chennai 144
Phoenix 144
Brussels 138
San Francisco 131
Denver 130
Jinan 128
Haiphong 127
Atlanta 120
Amsterdam 117
Johannesburg 117
Jakarta 116
Falls Church 115
Rio de Janeiro 112
Zhengzhou 112
Manchester 105
Moscow 101
Kunming 99
Guangzhou 98
Philadelphia 96
Bologna 95
Norwalk 95
Auburn Hills 94
Stockholm 90
Florence 89
Tashkent 88
Mountain View 85
Boston 81
Baghdad 80
Ningbo 80
Poplar 78
Mumbai 73
Belo Horizonte 67
Naples 66
Ankara 64
Düsseldorf 63
Orange 63
Redwood City 63
Biên Hòa 62
Quito 60
Verona 59
Totale 72.913
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.124
Farmacologia cellulare e molecolare, sistemi di trasmissione e autacoidi. Trasmissione purinergica 1.450
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 428
Progetto ex 60%- I recettori dell’adenosina come possibili “biomarkers” dei tumori colorettali. Studio su tessuti umani sani e tumorali e sulle cellule del sangue periferico. 425
Pharmacology of Adenosine Receptors: The State of the Art 423
Dose and time effects of caffeine intake on human platelet adenosine A2A receptors: functional and biochemical aspects 360
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 345
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 331
Caffeine alters A(2A) adenosine receptors and their function in human platelets 331
A glance at adenosine receptors: Novel target for antitumor therapy 322
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 317
Alterazioni dei recettori alfa(2) adrenergici delle piastrine umane nell'ipertensione essenziale 314
Psychostimulant effect of the synthetic cannabinoid JWH-018 and AKB48. Behavioural, neurochemical and Dopamine transporter scan imaging studies in mice 310
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 306
Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455 300
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine (medazepam) 297
The A3 adenosine receptor: history and perspectives 294
A(2B) adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway 294
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 291
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 286
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives as new potent and selective human A3 adenosine receptor antagonists. Molecular modeling studies and pharmacological evaluation 284
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects? 280
Recettori e trasduzione del segnale 278
Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease 273
Pulsed Electromagnetic Field Exposure Reduces Hypoxia and Inflammation Damage in Neuron-Like and Microglial Cells 273
Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fields 269
A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release 268
Human vascular kinin receptors of the B-2 type characterized by radioligand binding 268
Recettori e trasduzione del segnale 265
Adenosine receptors and human melanoma 264
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 262
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 261
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts 261
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 260
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 254
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 251
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 251
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter 251
Effect of low frequency electromagnetic fields on A2A adenosine receptors in human neutrophils. 249
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 249
Role and function of A2A and A3 adenosine receptors in patients with ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis 247
A(2A) adenosine receptors are up-regulated in lymphocytes from amyotrophic lateral sclerosis patients 247
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 246
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes. 246
Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells 246
Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies 245
Ala scan analogues of HOE 140. Synthesis and biological activities 244
Comparison of prazosin, terazosin and tamsulosin: Functional and binding studies in isolated prostatic and vascular human tissues 244
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 243
Alteration of A3 adenosine receptors in human neutrophils and low frequency electromagnetic fields 242
Adenosine A1 receptors in the rat brain in the kindling model of epilepsy 242
Multiple sclerosis lymphocytes upregulate A(2A) adenosine receptors that are antiinflammatory when stimulated 241
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 240
HIF-1 neuroprotection through erythropoietin increase in hypoxia: a role for A1 adenosine receptors 238
2 Aralkynyl and 2-heteroalkynyl derivatives of adenosine 5'-N-ethyluronamide as selective A2A adenosine receptor agonists 237
Cannabinoid CB2 receptor attenuates morphine-induced inflammatory responses in activated microglial cells 237
Adenosine modulates vascular endothelial growth factor expression via hypoxiainducible factor-1 in human glioblastoma cells. 236
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 236
Octadecyl, phenyl and cyano phases comparison for the RP-HPLC prediction of octanol-water partition coefficient 235
7-nitro-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one (nitrazepam) 235
Adenosine signaling contributes to ethanol-induced fatty liver in mice 234
Adenosine receptors and cancer 233
The activation of μ-opioid receptor potentiates LPS-induced NF-kB promoting an inflammatory phenotype in microglia 233
A3 Receptors are Overexpressed in Pleura from Mesothelioma Patients and Reduce Cell Growth via Akt/NF-kB Pathway. 232
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 231
Adenosine receptor targeting in health and disease 230
4-(4-Fluorobenzoyl)-1-[2-(4-iodo-2,5-dimethoxyphenyl)ethyl]piperidine and its derivatives: Synthesis and affinity at 5-HT(2A), 5-HT(2B) and 5- HT(2C) serotonin receptors 230
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 228
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 228
Alteration of adenosine receptore in patients with chronic obstructive pulmonary disease 228
Current status of A1 adenosine receptor allosteric enhancers 227
Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A2A Adenosine Receptor Inverse Agonists with Antinociceptive Activity 227
ALTERATION OF ADENOSINE RECEPTORS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE 226
A3 adenosine receptors are overexpressed in pleura from patients with mesothelioma and reduce malignant mesothelioma cell growth 226
van't Hoff Based Thermodynamics 226
Binding thermodynamics and intrinsic activity of adenosine A1 receptor ligands 225
A concerted binding study using binding measurements, X-ray structural data and molecular modeling on the stereochemical features responsible for the affinity of 6-arylpyrrolo[2,1-d][1,5]benzothiazepines to mitochondrial benzodiazepine receptors 225
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 225
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 225
[3H]-MRE 2029-F20, a novel selective antagonist radioligand, for the pharmacological and biochemical characterization of A2B receptors. 225
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 224
M3 muscarinic receptors in peripheral lung parenchima of patients with chronic obstructive pulmonary disease. 223
The Anti-Tumor Effect of A(3) Adenosine Receptors Is Potentiated by Pulsed Electromagnetic Fields in Cultured Neural Cancer Cells 223
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 223
Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension 222
A2A adenosine receptor upregulation correlates with disease activity in patients with systemic lupus erythematosus 222
Targeting A3 and A2A adenosine receptors in the fight against cancer 222
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 220
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 220
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 220
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 220
P2X1 and P2X3 Purinergic Receptors Differentially Modulate the Inflammatory Response in Human Osteoarthritic Synovial Fibroblasts 220
3H SCH 58261 labelling of functional A2A adenosine receptors in human neutrophil membranes 220
Binding and signaling studies disclose a potential allosteric site for cannabidiol in cannabinoid CB2 receptors 220
Adenosine Receptors as a Biological Pathway for the Anti-Inflammatory and Beneficial Effects of Low Frequency Low Energy Pulsed Electromagnetic Fields 220
Adenosine modulates HIF-1, VEGF, IL-8 and foam cells formation in a human model of hypoxic foam cells 219
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 219
Pathological overproduction: the bad side of adenosine 219
Receptor binding at two different temperatures to discriminate agonist and antagonist behaviour of adenosine A1 receptor ligands in rat brain 218
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 218
Totale 29.622
Categoria #
all - tutte 475.868
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 18.202
Totale 494.070


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20225.587 0 0 443 343 406 252 228 321 242 499 820 2.033
2022/20236.787 719 416 200 895 1.131 1.041 272 566 874 53 372 248
2023/20243.363 353 442 175 97 351 385 183 241 66 101 107 862
2024/202513.439 395 383 1.060 630 1.644 1.191 406 904 1.843 1.520 1.908 1.555
2025/202640.691 3.829 1.676 3.934 4.939 5.356 2.606 4.557 1.949 5.510 4.236 1.387 712
2026/20274.920 1.288 2.292 1.340 0 0 0 0 0 0 0 0 0
Totale 112.684