BOREA, Pier Andrea
 Distribuzione geografica
Continente #
NA - Nord America 61.739
AS - Asia 29.986
EU - Europa 21.331
SA - Sud America 4.587
Continente sconosciuto - Info sul continente non disponibili 682
AF - Africa 624
OC - Oceania 58
Totale 119.007
Nazione #
US - Stati Uniti d'America 60.116
SG - Singapore 10.676
CN - Cina 7.846
IT - Italia 4.606
DE - Germania 3.727
BR - Brasile 3.495
VN - Vietnam 3.194
FI - Finlandia 3.105
UA - Ucraina 3.093
HK - Hong Kong 2.508
TR - Turchia 2.385
GB - Regno Unito 1.815
SE - Svezia 1.228
FR - Francia 1.151
RU - Federazione Russa 927
CA - Canada 738
BD - Bangladesh 650
JP - Giappone 648
IN - India 612
PL - Polonia 469
MX - Messico 443
AR - Argentina 389
NL - Olanda 311
ID - Indonesia 238
ZA - Sudafrica 236
IQ - Iraq 195
ES - Italia 187
EC - Ecuador 173
CO - Colombia 172
BE - Belgio 144
PK - Pakistan 129
VE - Venezuela 121
LT - Lituania 101
UZ - Uzbekistan 98
SA - Arabia Saudita 94
JM - Giamaica 90
CR - Costa Rica 89
MY - Malesia 87
CL - Cile 85
CZ - Repubblica Ceca 85
PH - Filippine 85
MA - Marocco 84
TN - Tunisia 78
AT - Austria 75
AE - Emirati Arabi Uniti 73
PY - Paraguay 63
KE - Kenya 52
HN - Honduras 46
JO - Giordania 46
AU - Australia 45
KR - Corea 43
EG - Egitto 41
IE - Irlanda 40
IR - Iran 40
IL - Israele 39
NP - Nepal 33
TT - Trinidad e Tobago 33
GT - Guatemala 31
SV - El Salvador 31
DZ - Algeria 30
RO - Romania 30
NI - Nicaragua 29
TW - Taiwan 29
UY - Uruguay 29
PE - Perù 27
AZ - Azerbaigian 25
BO - Bolivia 25
KZ - Kazakistan 25
PT - Portogallo 25
AL - Albania 23
PR - Porto Rico 23
CH - Svizzera 22
TH - Thailandia 22
EU - Europa 21
ET - Etiopia 20
PS - Palestinian Territory 20
BG - Bulgaria 18
OM - Oman 18
LB - Libano 17
GR - Grecia 15
RS - Serbia 15
SN - Senegal 15
KG - Kirghizistan 14
PA - Panama 14
SY - Repubblica araba siriana 14
BH - Bahrain 13
DO - Repubblica Dominicana 13
QA - Qatar 13
HU - Ungheria 12
GP - Guadalupe 11
LV - Lettonia 11
MD - Moldavia 11
NO - Norvegia 11
NZ - Nuova Zelanda 11
AM - Armenia 10
BB - Barbados 10
BY - Bielorussia 10
HR - Croazia 10
BA - Bosnia-Erzegovina 9
DK - Danimarca 9
Totale 118.163
Città #
Singapore 6.962
Ashburn 6.248
Woodbridge 4.583
San Jose 4.127
Fairfield 3.675
Jacksonville 3.310
Chandler 2.911
Houston 2.908
Hong Kong 2.455
Santa Clara 2.440
Ann Arbor 2.405
Council Bluffs 2.399
Helsinki 2.277
Beijing 2.244
Wilmington 1.664
Dallas 1.631
Seattle 1.567
Cambridge 1.158
Izmir 1.123
Ho Chi Minh City 1.074
Nanjing 1.020
Los Angeles 960
Hanoi 773
Princeton 732
New York 686
Tokyo 627
Lauterbourg 559
Milan 549
Boardman 534
Munich 527
Ferrara 474
Warsaw 403
São Paulo 360
San Diego 356
Nanchang 324
Shanghai 319
Shenyang 306
Falkenstein 290
Mexico City 273
Orem 244
Hefei 243
Rome 232
Chicago 229
Tianjin 221
London 214
Buffalo 211
Dearborn 205
Hebei 204
Toronto 199
Turku 194
Changsha 189
Bremen 183
Frankfurt am Main 181
Phoenix 181
Montreal 179
Brooklyn 176
San Mateo 176
The Dalles 171
Addison 170
Jiaxing 169
Atlanta 165
Da Nang 155
Denver 153
San Francisco 151
Chennai 144
Brussels 138
Jinan 128
Haiphong 127
Washington 123
Naples 118
Amsterdam 117
Johannesburg 117
Jakarta 116
Falls Church 115
Rio de Janeiro 113
Bologna 112
Zhengzhou 112
Manchester 106
Philadelphia 106
Florence 102
Moscow 101
Kunming 99
Guangzhou 98
Norwalk 98
Auburn Hills 94
Stockholm 94
Boston 92
Tashkent 88
Mountain View 85
Baghdad 80
Ningbo 80
Poplar 78
Mumbai 77
San José 70
Belo Horizonte 67
Verona 66
Ankara 64
Orange 64
Biên Hòa 63
Düsseldorf 63
Totale 75.543
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.142
Farmacologia cellulare e molecolare, sistemi di trasmissione e autacoidi. Trasmissione purinergica 1.471
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 453
Pharmacology of Adenosine Receptors: The State of the Art 450
Progetto ex 60%- I recettori dell’adenosina come possibili “biomarkers” dei tumori colorettali. Studio su tessuti umani sani e tumorali e sulle cellule del sangue periferico. 446
Dose and time effects of caffeine intake on human platelet adenosine A2A receptors: functional and biochemical aspects 430
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 366
Caffeine alters A(2A) adenosine receptors and their function in human platelets 360
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 346
A glance at adenosine receptors: Novel target for antitumor therapy 337
Psychostimulant effect of the synthetic cannabinoid JWH-018 and AKB48. Behavioural, neurochemical and Dopamine transporter scan imaging studies in mice 337
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 329
Alterazioni dei recettori alfa(2) adrenergici delle piastrine umane nell'ipertensione essenziale 326
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 317
Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455 315
The A3 adenosine receptor: history and perspectives 312
A(2B) adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway 311
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine (medazepam) 308
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 307
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 301
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives as new potent and selective human A3 adenosine receptor antagonists. Molecular modeling studies and pharmacological evaluation 298
Pulsed Electromagnetic Field Exposure Reduces Hypoxia and Inflammation Damage in Neuron-Like and Microglial Cells 290
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects? 289
Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease 288
A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release 288
Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fields 287
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 286
Recettori e trasduzione del segnale 284
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 280
Human vascular kinin receptors of the B-2 type characterized by radioligand binding 279
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 278
Recettori e trasduzione del segnale 274
Adenosine receptors and human melanoma 273
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts 270
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 266
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 266
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes. 266
Adenosine signaling contributes to ethanol-induced fatty liver in mice 265
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 264
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter 264
Comparison of prazosin, terazosin and tamsulosin: Functional and binding studies in isolated prostatic and vascular human tissues 261
Ala scan analogues of HOE 140. Synthesis and biological activities 260
Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells 259
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 258
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 258
Effect of low frequency electromagnetic fields on A2A adenosine receptors in human neutrophils. 257
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 255
2 Aralkynyl and 2-heteroalkynyl derivatives of adenosine 5'-N-ethyluronamide as selective A2A adenosine receptor agonists 255
Role and function of A2A and A3 adenosine receptors in patients with ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis 255
4-(4-Fluorobenzoyl)-1-[2-(4-iodo-2,5-dimethoxyphenyl)ethyl]piperidine and its derivatives: Synthesis and affinity at 5-HT(2A), 5-HT(2B) and 5- HT(2C) serotonin receptors 254
A(2A) adenosine receptors are up-regulated in lymphocytes from amyotrophic lateral sclerosis patients 254
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 252
Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies 251
Adenosine A1 receptors in the rat brain in the kindling model of epilepsy 251
Alteration of A3 adenosine receptors in human neutrophils and low frequency electromagnetic fields 250
Adenosine modulates vascular endothelial growth factor expression via hypoxiainducible factor-1 in human glioblastoma cells. 250
7-nitro-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one (nitrazepam) 250
Multiple sclerosis lymphocytes upregulate A(2A) adenosine receptors that are antiinflammatory when stimulated 249
Adenosine receptors and cancer 248
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 247
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 246
HIF-1 neuroprotection through erythropoietin increase in hypoxia: a role for A1 adenosine receptors 246
Cannabinoid CB2 receptor attenuates morphine-induced inflammatory responses in activated microglial cells 245
A3 Receptors are Overexpressed in Pleura from Mesothelioma Patients and Reduce Cell Growth via Akt/NF-kB Pathway. 244
The activation of μ-opioid receptor potentiates LPS-induced NF-kB promoting an inflammatory phenotype in microglia 244
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 244
Adenosine receptor targeting in health and disease 242
[3H]-MRE 2029-F20, a novel selective antagonist radioligand, for the pharmacological and biochemical characterization of A2B receptors. 242
Octadecyl, phenyl and cyano phases comparison for the RP-HPLC prediction of octanol-water partition coefficient 241
Targeting A3 and A2A adenosine receptors in the fight against cancer 241
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 240
P2X1 and P2X3 Purinergic Receptors Differentially Modulate the Inflammatory Response in Human Osteoarthritic Synovial Fibroblasts 240
Current status of A1 adenosine receptor allosteric enhancers 240
A concerted binding study using binding measurements, X-ray structural data and molecular modeling on the stereochemical features responsible for the affinity of 6-arylpyrrolo[2,1-d][1,5]benzothiazepines to mitochondrial benzodiazepine receptors 239
A3 adenosine receptors are overexpressed in pleura from patients with mesothelioma and reduce malignant mesothelioma cell growth 239
A2A adenosine receptor upregulation correlates with disease activity in patients with systemic lupus erythematosus 238
M3 muscarinic receptors in peripheral lung parenchima of patients with chronic obstructive pulmonary disease. 236
Binding thermodynamics and intrinsic activity of adenosine A1 receptor ligands 236
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 236
Adenosine modulates HIF-1, VEGF, IL-8 and foam cells formation in a human model of hypoxic foam cells 236
3H SCH 58261 labelling of functional A2A adenosine receptors in human neutrophil membranes 236
van't Hoff Based Thermodynamics 236
Alteration of adenosine receptore in patients with chronic obstructive pulmonary disease 236
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 235
Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension 235
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 235
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 235
Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A2A Adenosine Receptor Inverse Agonists with Antinociceptive Activity 235
ALTERATION OF ADENOSINE RECEPTORS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE 234
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 234
Adenosine Receptors as a Biological Pathway for the Anti-Inflammatory and Beneficial Effects of Low Frequency Low Energy Pulsed Electromagnetic Fields 234
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 233
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 233
[3H]MRE2029F20 a new selective antagonist radioligand for the human A2B adenosine receptors. 233
[3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 233
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 233
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 232
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 232
THERMODYNAMICS OF A2B ADENOSINE RECEPTOR BINDING DISCRIMINATES AGONISTIC FROM ANTAGONISTIC BEHAVIOUR 232
Pathological overproduction: the bad side of adenosine 232
Totale 31.086
Categoria #
all - tutte 501.709
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 19.170
Totale 520.879


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20225.154 0 0 0 343 406 252 229 321 245 500 823 2.035
2022/20236.799 720 418 200 898 1.133 1.042 273 566 876 53 372 248
2023/20243.370 354 442 175 97 353 386 183 242 66 101 107 864
2024/202513.457 395 383 1.062 633 1.646 1.192 406 904 1.847 1.522 1.911 1.556
2025/202640.756 3.833 1.684 3.942 4.949 5.365 2.610 4.561 1.952 5.516 4.244 1.388 712
2026/202711.089 1.290 2.298 4.095 3.406 0 0 0 0 0 0 0 0
Totale 119.007