BOREA, Pier Andrea
 Distribuzione geografica
Continente #
NA - Nord America 33.798
EU - Europa 11.711
AS - Asia 6.464
SA - Sud America 31
OC - Oceania 25
Continente sconosciuto - Info sul continente non disponibili 24
AF - Africa 9
Totale 52.062
Nazione #
US - Stati Uniti d'America 33.765
CN - Cina 4.008
UA - Ucraina 2.959
DE - Germania 2.474
IT - Italia 2.474
TR - Turchia 2.186
GB - Regno Unito 1.184
SE - Svezia 1.051
FI - Finlandia 643
RU - Federazione Russa 270
PL - Polonia 258
FR - Francia 196
HK - Hong Kong 94
BE - Belgio 86
VN - Vietnam 48
IN - India 41
IR - Iran 30
NL - Olanda 28
CA - Canada 27
AU - Australia 21
EU - Europa 21
CL - Cile 13
AT - Austria 12
RO - Romania 12
ES - Italia 11
KR - Corea 11
BR - Brasile 10
CZ - Repubblica Ceca 8
JP - Giappone 8
SG - Singapore 8
IE - Irlanda 7
IL - Israele 6
PT - Portogallo 6
AR - Argentina 5
CH - Svizzera 5
GR - Grecia 4
HR - Croazia 4
MX - Messico 4
NZ - Nuova Zelanda 4
TW - Taiwan 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BD - Bangladesh 3
BG - Bulgaria 3
DZ - Algeria 3
EG - Egitto 3
IM - Isola di Man 3
AL - Albania 2
DK - Danimarca 2
IQ - Iraq 2
LB - Libano 2
MA - Marocco 2
MD - Moldavia 2
NO - Norvegia 2
PH - Filippine 2
PS - Palestinian Territory 2
SI - Slovenia 2
AE - Emirati Arabi Uniti 1
BO - Bolivia 1
CO - Colombia 1
EC - Ecuador 1
ID - Indonesia 1
KH - Cambogia 1
LT - Lituania 1
MC - Monaco 1
ME - Montenegro 1
MY - Malesia 1
NI - Nicaragua 1
NP - Nepal 1
PK - Pakistan 1
SA - Arabia Saudita 1
SV - El Salvador 1
TH - Thailandia 1
TN - Tunisia 1
UZ - Uzbekistan 1
Totale 52.062
Città #
Woodbridge 4.579
Fairfield 3.672
Jacksonville 3.290
Chandler 2.908
Houston 2.826
Ann Arbor 2.404
Ashburn 2.030
Wilmington 1.651
Seattle 1.509
Cambridge 1.157
Izmir 1.118
Nanjing 1.014
Beijing 714
Princeton 711
Boardman 459
Ferrara 407
Milan 346
San Diego 343
Nanchang 323
Shenyang 303
Shanghai 241
Warsaw 236
Hebei 204
Dearborn 203
Bremen 182
San Mateo 176
Changsha 173
Tianjin 173
Addison 170
Jiaxing 167
New York 164
Jinan 119
Falls Church 115
Zhengzhou 102
Kunming 95
Auburn Hills 94
Norwalk 92
Hong Kong 91
Mountain View 85
Brussels 84
Ningbo 78
Philadelphia 70
Orange 63
Redwood City 63
Düsseldorf 60
London 59
Guangzhou 58
Rome 52
Des Moines 51
Verona 47
Dong Ket 46
Florence 45
Los Angeles 45
Washington 44
Augusta 40
Lanzhou 39
Taizhou 39
Indiana 37
Tappahannock 36
Chicago 30
Bologna 29
Helsinki 29
Hangzhou 27
Redmond 27
Haikou 24
Torino 23
Ardabil 21
Bari 20
Hefei 20
Kilburn 20
Napoli 20
Leawood 16
Padova 15
Munich 14
Naples 13
Changchun 12
Ferrara di Monte Baldo 12
Monmouth Junction 11
Taiyuan 11
Camerino 10
San Francisco 10
Catania 9
Corvallis 9
Fuzhou 9
Mumbai 9
Chiswick 8
Edinburgh 8
Hounslow 8
New Bedfont 8
Caserta 7
Kitzbuhel 7
Mcallen 7
Palermo 7
Toronto 7
Turin 7
Yellow Springs 7
Bucharest 6
Dallas 6
Foggia 6
Messina 6
Totale 36.257
Nome #
Farmacologia cellulare e molecolare, sistemi di trasmissione e autacoidi. Trasmissione purinergica 1.097
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 283
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 218
Progetto ex 60%- I recettori dell’adenosina come possibili “biomarkers” dei tumori colorettali. Studio su tessuti umani sani e tumorali e sulle cellule del sangue periferico. 209
A glance at adenosine receptors: Novel target for antitumor therapy 191
Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455 184
Alterazioni dei recettori alfa(2) adrenergici delle piastrine umane nell'ipertensione essenziale 175
The A3 adenosine receptor: history and perspectives 158
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 156
Receptor binding thermodynamics as a tool for linking drug efficacy and affinity 151
Cannabinoid CB2 receptor attenuates morphine-induced inflammatory responses in activated microglial cells 151
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 149
Recettori e trasduzione del segnale 147
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 145
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 143
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 143
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 140
Human vascular kinin receptors of the B-2 type characterized by radioligand binding 139
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 139
2 Aralkynyl and 2-heteroalkynyl derivatives of adenosine 5'-N-ethyluronamide as selective A2A adenosine receptor agonists 138
Psychostimulant effect of the synthetic cannabinoid JWH-018 and AKB48. Behavioural, neurochemical and Dopamine transporter scan imaging studies in mice 138
Binding and signaling studies disclose a potential allosteric site for cannabidiol in cannabinoid CB2 receptors 138
Pathological overproduction: the bad side of adenosine 138
Pharmacology of Adenosine Receptors: The State of the Art 137
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts 136
Current status of A1 adenosine receptor allosteric enhancers 136
Adenosine receptors and human melanoma 133
Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors 133
Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells. 132
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 131
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 131
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 131
Therapeutic potential of adenosine receptor antagonists and agonists 130
Adenosine A1 receptors in the rat brain in the kindling model of epilepsy 130
Adenosine receptor targeting in health and disease 129
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 129
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine (medazepam) 128
Octadecyl, phenyl and cyano phases comparison for the RP-HPLC prediction of octanol-water partition coefficient 127
Receptor binding at two different temperatures to discriminate agonist and antagonist behaviour of adenosine A1 receptor ligands in rat brain 127
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 127
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 125
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells. 125
null 125
Multiple sclerosis lymphocytes upregulate A(2A) adenosine receptors that are antiinflammatory when stimulated 125
The activation of μ-opioid receptor potentiates LPS-induced NF-kB promoting an inflammatory phenotype in microglia 125
Pulsed Electromagnetic Field Exposure Reduces Hypoxia and Inflammation Damage in Neuron-Like and Microglial Cells 123
A Consensus Panel Review of Central Nervous System Effects of the Exposure to Low-Intensity Extremely Low-Frequency Magnetic Fields 123
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 123
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 122
Effects of selective A1 and A2 adenosine receptor agonists on cardiovascular tissues 121
Pharmacology of [Tyr(1)]nociceptin analogs: receptor binding and bioassay studies 121
Comparison of Prazosin, Terazosin and Tamsulosin: Functional and Binding Studies in Isolated Prostatic and Vascular Human Tissues. 121
null 121
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 120
A(2A) adenosine receptors are up-regulated in lymphocytes from amyotrophic lateral sclerosis patients 120
Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors 119
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 119
Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A2A Adenosine Receptor Inverse Agonists with Antinociceptive Activity 119
Opioid agonists and antagonists. Peptides containing N-terminal allyl groups and/or a thiomethylene linkage in place of a peptide bond 118
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 118
null 118
Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors 118
Temperature dependence of [3H]PAF binding to washed human platelets 117
Adenosine modulates vascular endothelial growth factor expression via hypoxiainducible factor-1 in human glioblastoma cells. 117
Adenosine receptors and cancer 117
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives as new potent and selective human A3 adenosine receptor antagonists. Molecular modeling studies and pharmacological evaluation 117
A(2B) adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway 117
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 116
Alteration of A3 adenosine receptors in human neutrophils and low frequency electromagnetic fields 116
Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease 116
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 116
Ala scan analogues of HOE 140. Synthesis and biological activities 115
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 115
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects? 115
Role and function of A2A and A3 adenosine receptors in patients with ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis 114
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes. 114
Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells 114
Rm and logP values of 5-nitroimidazoles 113
null 113
Binding thermodynamics at A1 and A2A adenosine receptors 113
Biochemical characterization of A1 adenosine receptors: experimental evaluation of their binding and intrinsic activity parameters 113
MODULATION OF THE AKT/RAS/RAF/MEK/ERK PATHWAY BY A3 ADENOSINE RECEPTOR 113
Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E(2) and cytokine release in human osteoarthritic synovial fibroblasts 113
Cholesterol esters of the liver, of the plasma and of the lipoproteins of rats poisoned with CCl4 112
Antagonism towards endogenous adenosine and inhibition of cGIPDE in the cardiac effects amrinone, milrinone and related analogues 112
Thermodynamics of A2B adenosine receptor binding discriminates agonistic from antagonistic behaviour. 112
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT(1A) receptor ligands 112
null 112
A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release 112
Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension 111
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 111
Synthesis, radiolabeling, and preliminary biological evaluation of [H-3]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl )-piperazine, a potent antagonist radioligand for the P2X(7) receptor 111
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 111
F638 a nitric oxide (NO)-donating gabapentin, NCX 1236, reverses the development of mechanical allodynia in streptozotocin-treated diabetic mice. 111
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 111
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 111
New potent and selective human adenosine A3 receptor antagonists. 111
The A3 adenosine receptor: an enigmatic player in cell biology. 110
Adenosine signaling contributes to ethanol-induced fatty liver in mice 110
Binding thermodynamics and intrinsic activity of adenosine A1 receptor ligands 110
Totale 13.870
Categoria #
all - tutte 171.130
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 6.671
Totale 177.801


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20195.092 0 0 0 0 0 0 0 0 0 1.189 1.252 2.651
2019/202010.169 1.984 281 267 1.420 559 1.192 807 1.035 661 1.296 499 168
2020/20217.905 757 776 288 923 354 860 233 937 154 1.054 1.109 460
2021/20226.405 141 667 443 343 406 252 229 321 245 500 823 2.035
2022/20236.799 720 418 200 898 1.133 1.042 273 566 876 53 372 248
2023/20242.342 354 442 175 97 353 386 183 242 66 44 0 0
Totale 52.677