IRIS
ROMAGNOLI, Romeo
 Distribuzione geografica
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Continente #
NA - Nord America 16533
EU - Europa 5238
AS - Asia 2668
SA - Sud America 15
Continente sconosciuto - Info sul continente non disponibili 13
OC - Oceania 4
AF - Africa 3
Totale 24474
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Nazione #
US - Stati Uniti d'America 16517
CN - Cina 1678
DE - Germania 1648
UA - Ucraina 1240
TR - Turchia 866
IT - Italia 518
GB - Regno Unito 504
SE - Svezia 445
RU - Federazione Russa 284
FI - Finlandia 269
BE - Belgio 112
PL - Polonia 89
FR - Francia 82
VN - Vietnam 63
IN - India 16
KR - Corea 15
AT - Austria 13
CA - Canada 10
EU - Europa 10
JP - Giappone 9
CO - Colombia 8
IR - Iran 7
ES - Italia 6
MX - Messico 6
NL - Olanda 6
CL - Cile 5
AU - Australia 4
PT - Portogallo 4
A2 - ???statistics.table.value.countryCode.A2??? 3
GR - Grecia 3
BR - Brasile 2
CH - Svizzera 2
EG - Egitto 2
LT - Lituania 2
MD - Moldavia 2
RO - Romania 2
TW - Taiwan 2
BD - Bangladesh 1
BG - Bulgaria 1
GE - Georgia 1
HK - Hong Kong 1
HR - Croazia 1
HU - Ungheria 1
ID - Indonesia 1
IL - Israele 1
KH - Cambogia 1
LK - Sri Lanka 1
ME - Montenegro 1
MN - Mongolia 1
NO - Norvegia 1
PH - Filippine 1
PK - Pakistan 1
RS - Serbia 1
SA - Arabia Saudita 1
SG - Singapore 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
Totale 24474
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Città #
Fairfield 2520
Woodbridge 2398
Houston 1540
Jacksonville 1381
Chandler 1308
Ann Arbor 1234
Ashburn 946
Seattle 897
Wilmington 845
Cambridge 762
Izmir 468
Nanjing 432
Beijing 366
Princeton 313
San Diego 226
Ferrara 212
Boardman 209
Shenyang 146
Nanchang 121
Milan 117
Brussels 111
Bremen 101
Warsaw 87
Hebei 85
Changsha 83
San Mateo 80
Jiaxing 77
Tianjin 73
Dong Ket 62
Philadelphia 60
Jinan 50
Norwalk 48
Zhengzhou 45
Falls Church 44
Dearborn 43
Kunming 43
Addison 42
Mountain View 42
Redwood City 35
Orange 33
Indiana 27
Paris 25
Auburn Hills 23
Ningbo 23
Guangzhou 22
London 22
Taizhou 21
Des Moines 20
Verona 18
Chicago 17
Shanghai 15
Los Angeles 14
Lanzhou 13
New York 12
Redmond 12
Munich 11
Vienna 11
Bari 10
Haikou 10
Helsinki 10
Hangzhou 9
Augusta 8
Düsseldorf 8
Leawood 8
Fuzhou 7
Mcallen 7
Medellín 6
Monmouth Junction 6
Montréal 6
Xian 6
Changchun 5
Yellow Springs 5
Bologna 4
Hefei 4
Chongqing 3
Mysore 3
Padova 3
Perivale 3
Saint Petersburg 3
San Francisco 3
Sevilla 3
Tappahannock 3
Tokyo 3
Andover 2
Baltimore 2
Bangalore 2
Boleslaw 2
Calvizzano 2
Camerino 2
Cosenza 2
Cupertino 2
Dresden 2
Ferrara di Monte Baldo 2
Granada 2
Kitzbuhel 2
Massa Fiscaglia 2
Moscow 2
Napoli 2
Novosibirsk 2
Palo Alto 2
Totale 18171
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Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 260
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 153
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity. 147
A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion 146
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 146
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 143
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 138
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 137
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 135
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 134
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 134
Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology 133
Current status of A1 adenosine receptor allosteric enhancers 133
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 133
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 131
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition 131
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 130
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 129
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1, 4]benzodiazepine and minor-groove-binding oligopyrrole carriers. 129
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 128
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 128
A one-pot synthesis of nitrohydroxylated pyrrolidine and piperidine ring systems by tandem Michael-Henry reaction 127
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 127
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 127
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 126
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 126
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 126
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 126
DNA minor groove binders as potential antitumor and antimicrobial agents 125
Design, Synthesis, DNA Binding, and Biological Evaluation of Water-Soluble Hybrid Molecules Containing Two Pyrazole Analogues of the Alkylating Cyclopropylpyrroloindole (CPI) Subunit of the Antitumor Agent CC-1065 and Polypyrrole Minor Groove Binders. 125
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 124
2-Arylamino-4-Amino-5-Aroylthiazoles. "One-Pot" Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization. 124
Novel 8-heterocyclyl xanthine derivatives in drug development - an update. 124
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 124
Hybrid molecules based on distamycin A as potential antitumor agents 124
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 122
null 121
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 121
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 121
null 121
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 121
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 120
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 120
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 120
null 120
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 120
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 118
Synthesis and antitumor activity of novel distamycin derivatives 118
Allosteric modulators for the A1-adenosine receptor 118
null 118
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 117
MASTERING BETA-KETO-ESTERS 117
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 115
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 115
Recent improvements in the development of A2B adenosine receptor agonists. 114
Synthesis of melodienone and 7-hydroxy-6-hydromelodienone, two heptenes from Melodorum Fruticosum 114
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 113
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 113
A3 adenosine receptor antagonists: History and future perspectives 113
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 112
null 112
Allosteric Modulators of the A1 Adenosine receptor 111
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 110
null 110
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 109
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 109
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 109
null 109
Total synthesis of (+/-)-epibatidine 109
New potent and selective human adenosine A3 receptor antagonists. 109
DNA minor groove alkylating agents structurally related to distamycin A 108
N-arylpiperazine modified analogues of the P2X(7) receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts 108
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 108
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N-(substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor. 108
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 107
Synthesis, radiolabeling, and preliminary biological evaluation of [H-3]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl )-piperazine, a potent antagonist radioligand for the P2X(7) receptor 107
Allosteric modulators of the A1 adenosine receptor 107
Allosteric enhancers for A(1) adenosine receptor 106
Enantiodivergent synthesis of 2-hydroxymethyl-3-hydroxy-4-nitro-pyrrolidines through tandem Michael-Henry reaction using L-serine as the chiral educt. 106
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 106
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. 106
Recent improvements in the development of A2B adenosine receptor agonists 106
Allosteric modulation of A1-adenosine receptor: A review 106
A new synthetic approach to indazole synthesis 105
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity. 105
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 104
Synthesis and biological evaluation of a series of 2-(3,4,5-trimethoxybenzoyl)-indol-3-yl acetic acid derivatives as potential agents against human leukemia K562 cells 104
Design, synthesis and biological activity of 5-fluorouracil-distamycin hybrids 104
Hybrid molecules between distamycin A and active moieties of antitumor agents 104
Synthesis, biological activity and molecular modeling studies of 1,2,3,4-tetrahydroisoquinoline derivatives as conformationally constrained analogues of KN62, a potent antagonist of the P2X(7)-receptor containing a tyrosine moiety 103
null 103
Benzoyl and cinnamoyl nitrogen mustard derivatives of benzoheterocyclic analogues of the tallimustine: Synthesis and antitumour activity 102
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 102
null 102
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 102
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 101
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5- (3′,4′,5′-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent 101
Design, synthesis and biological activity of a pyrrolo[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid 100
Synthesis and Biological Evaluation of 2-(3’,4’,5’-Trimethoxybenzoyl)-3-Aryl/ArylaminoBenzo[b]thiophene Derivatives as a Novel Class of Antiproliferative Agents 100
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 100
Totale 11903
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Categoria #
all - tutte 44387
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 197
Totale 44584
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/2018435 0000 00 00 392939112
2018/20194163 758472193 10240 50119 2776098301361
2019/20205631 946202186814 392630 464548 436604301108
2020/20213815 372342196420 153361 112472 87527459314
2021/20223062 116307271154 169131 143142 100238329962
2022/20232781 31817574421 526456 118325 368000
Totale 24769