ROMAGNOLI, Romeo
 Distribuzione geografica
Continente #
NA - Nord America 17.794
EU - Europa 5.644
AS - Asia 2.787
SA - Sud America 18
Continente sconosciuto - Info sul continente non disponibili 13
OC - Oceania 6
AF - Africa 3
Totale 26.265
Nazione #
US - Stati Uniti d'America 17.777
CN - Cina 1.772
DE - Germania 1.657
UA - Ucraina 1.240
TR - Turchia 866
GB - Regno Unito 575
IT - Italia 534
SE - Svezia 445
BE - Belgio 373
RU - Federazione Russa 284
FI - Finlandia 271
PL - Polonia 89
FR - Francia 83
VN - Vietnam 63
AT - Austria 43
HK - Hong Kong 22
IN - India 17
KR - Corea 15
CA - Canada 11
CZ - Repubblica Ceca 10
EU - Europa 10
CO - Colombia 9
JP - Giappone 9
IR - Iran 7
NL - Olanda 7
ES - Italia 6
MX - Messico 6
AU - Australia 5
CL - Cile 5
BR - Brasile 4
PT - Portogallo 4
A2 - ???statistics.table.value.countryCode.A2??? 3
GR - Grecia 3
LT - Lituania 3
CH - Svizzera 2
EG - Egitto 2
HR - Croazia 2
MD - Moldavia 2
PK - Pakistan 2
RO - Romania 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
AF - Afghanistan, Repubblica islamica di 1
BD - Bangladesh 1
BG - Bulgaria 1
GE - Georgia 1
HU - Ungheria 1
ID - Indonesia 1
IE - Irlanda 1
IL - Israele 1
IM - Isola di Man 1
KH - Cambogia 1
LK - Sri Lanka 1
MC - Monaco 1
ME - Montenegro 1
MN - Mongolia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
RS - Serbia 1
SA - Arabia Saudita 1
SG - Singapore 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
Totale 26.265
Città #
Fairfield 2.520
Woodbridge 2.398
Houston 1.540
Ashburn 1.401
Jacksonville 1.381
Chandler 1.308
Ann Arbor 1.234
Seattle 897
Wilmington 845
Cambridge 762
Izmir 468
Nanjing 432
Brussels 372
Beijing 369
Princeton 313
San Diego 226
Ferrara 216
Boardman 209
Shenyang 146
Nanchang 121
Milan 119
Shanghai 104
Bremen 101
Warsaw 87
Hebei 85
Changsha 83
San Mateo 80
New York 78
Jiaxing 77
Tianjin 73
Dong Ket 62
Philadelphia 60
Jinan 50
Norwalk 48
Zhengzhou 45
Falls Church 44
Dearborn 43
Kunming 43
Addison 42
London 42
Mountain View 42
Redwood City 35
Orange 33
Vienna 29
Indiana 27
Paris 25
Washington 24
Auburn Hills 23
Ningbo 23
Guangzhou 22
Taizhou 21
Des Moines 20
Hong Kong 20
Tappahannock 20
Chicago 19
Verona 18
Los Angeles 14
Lanzhou 13
Helsinki 12
Redmond 12
Munich 11
Bari 10
Brno 10
Haikou 10
Kilburn 10
Hangzhou 9
Augusta 8
Düsseldorf 8
Leawood 8
Fuzhou 7
Mcallen 7
Bologna 6
Medellín 6
Monmouth Junction 6
Montréal 6
Prescot 6
Xian 6
Acton 5
Changchun 5
Yellow Springs 5
Chiswick 4
Ferrara di Monte Baldo 4
Hanover 4
Hefei 4
New Bedfont 4
Wandsworth 4
Chongqing 3
Hounslow 3
Mysore 3
Padova 3
Perivale 3
Saint Petersburg 3
San Francisco 3
Sevilla 3
Tokyo 3
Villafranca Padovana 3
Andover 2
Baltimore 2
Bangalore 2
Bogotá 2
Totale 19.187
Nome #
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 358
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 291
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 166
A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion 161
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity. 160
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 157
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 154
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 150
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 148
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 148
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition 146
A one-pot synthesis of nitrohydroxylated pyrrolidine and piperidine ring systems by tandem Michael-Henry reaction 145
2-Arylamino-4-Amino-5-Aroylthiazoles. "One-Pot" Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization. 139
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 139
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 139
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 139
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 138
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 138
Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology 137
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 137
Design, Synthesis, DNA Binding, and Biological Evaluation of Water-Soluble Hybrid Molecules Containing Two Pyrazole Analogues of the Alkylating Cyclopropylpyrroloindole (CPI) Subunit of the Antitumor Agent CC-1065 and Polypyrrole Minor Groove Binders. 137
Current status of A1 adenosine receptor allosteric enhancers 136
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 136
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 134
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 134
MASTERING BETA-KETO-ESTERS 133
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 133
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 133
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 132
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 132
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 132
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 132
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 132
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 132
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 131
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 131
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 131
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 130
DNA minor groove binders as potential antitumor and antimicrobial agents 129
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 129
Allosteric modulators for the A1-adenosine receptor 128
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 127
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 126
Hybrid molecules based on distamycin A as potential antitumor agents 126
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 125
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 124
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 123
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 123
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 123
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 122
A3 adenosine receptor antagonists: History and future perspectives 122
null 121
Synthesis and antitumor activity of novel distamycin derivatives 121
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 121
null 121
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 120
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 120
Recent improvements in the development of A2B adenosine receptor agonists. 120
null 120
Allosteric enhancers for A(1) adenosine receptor 119
null 118
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 117
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. 117
Synthesis of melodienone and 7-hydroxy-6-hydromelodienone, two heptenes from Melodorum Fruticosum 116
N-arylpiperazine modified analogues of the P2X(7) receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts 115
Allosteric Modulators of the A1 Adenosine receptor 115
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 115
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 115
Allosteric modulation of A1-adenosine receptor: A review 115
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 115
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 114
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 114
DNA minor groove alkylating agents structurally related to distamycin A 113
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 113
A new synthetic approach to indazole synthesis 113
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 113
Total synthesis of (+/-)-epibatidine 113
null 112
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 112
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 111
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 111
Synthesis, radiolabeling, and preliminary biological evaluation of [H-3]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl )-piperazine, a potent antagonist radioligand for the P2X(7) receptor 111
Design, synthesis and biological activity of 5-fluorouracil-distamycin hybrids 111
New potent and selective human adenosine A3 receptor antagonists. 111
Enantiodivergent synthesis of 2-hydroxymethyl-3-hydroxy-4-nitro-pyrrolidines through tandem Michael-Henry reaction using L-serine as the chiral educt 110
null 110
Recent improvements in the development of A2B adenosine receptor agonists 110
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 109
Allosteric modulators of the A1 adenosine receptor 109
null 109
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 108
Synthesis and biological evaluation of a series of 2-(3,4,5-trimethoxybenzoyl)-indol-3-yl acetic acid derivatives as potential agents against human leukemia K562 cells 108
Hybrid molecules between distamycin A and active moieties of antitumor agents 108
2-aminothiophene-3-carboxylic acid ester derivatives as novel highly selective cytostatic agents 107
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5- (3′,4′,5′-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent 106
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 106
Synthesis, biological activity and molecular modeling studies of 1,2,3,4-tetrahydroisoquinoline derivatives as conformationally constrained analogues of KN62, a potent antagonist of the P2X(7)-receptor containing a tyrosine moiety 105
Benzoyl and cinnamoyl nitrogen mustard derivatives of benzoheterocyclic analogues of the tallimustine: Synthesis and antitumour activity 105
A new synthetic approach to pyrazolo[3,4-c]-1,2,5-oxadiazoles 104
Design, synthesis and biological activity of a pyrrolo[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid 103
Totale 12.838
Categoria #
all - tutte 80.229
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 379
Totale 80.608


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20193.096 0 0 0 0 0 0 0 19 277 609 830 1.361
2019/20205.631 946 202 186 814 392 630 464 548 436 604 301 108
2020/20213.815 372 342 196 420 153 361 112 472 87 527 459 314
2021/20223.062 116 307 271 154 169 131 143 142 100 238 329 962
2022/20233.218 318 175 74 421 526 456 118 325 396 27 282 100
2023/20241.363 161 305 93 47 149 197 67 344 0 0 0 0
Totale 26.569