ROMAGNOLI, Romeo
 Distribuzione geografica
Continente #
NA - Nord America 27.219
AS - Asia 13.498
EU - Europa 11.578
SA - Sud America 2.163
Continente sconosciuto - Info sul continente non disponibili 350
AF - Africa 284
OC - Oceania 17
Totale 55.109
Nazione #
US - Stati Uniti d'America 26.687
SG - Singapore 4.901
FI - Finlandia 4.268
CN - Cina 3.611
DE - Germania 2.127
BR - Brasile 1.691
VN - Vietnam 1.372
UA - Ucraina 1.316
HK - Hong Kong 1.215
TR - Turchia 953
GB - Regno Unito 826
IT - Italia 789
RU - Federazione Russa 576
FR - Francia 513
SE - Svezia 493
IN - India 261
JP - Giappone 243
BD - Bangladesh 237
CA - Canada 236
MX - Messico 208
PL - Polonia 183
AR - Argentina 160
ID - Indonesia 120
ZA - Sudafrica 111
IQ - Iraq 104
ES - Italia 91
NL - Olanda 85
CO - Colombia 76
PK - Pakistan 73
BE - Belgio 71
EC - Ecuador 67
VE - Venezuela 63
SA - Arabia Saudita 45
UZ - Uzbekistan 44
LT - Lituania 42
PH - Filippine 40
MA - Marocco 39
AT - Austria 38
EG - Egitto 35
AE - Emirati Arabi Uniti 34
TN - Tunisia 32
MY - Malesia 31
CL - Cile 29
KR - Corea 27
CZ - Repubblica Ceca 26
PY - Paraguay 26
IL - Israele 22
IE - Irlanda 18
KE - Kenya 17
TW - Taiwan 17
AU - Australia 16
NP - Nepal 16
PE - Perù 16
UY - Uruguay 16
CR - Costa Rica 15
TH - Thailandia 15
AZ - Azerbaigian 14
BO - Bolivia 14
JM - Giamaica 12
JO - Giordania 12
OM - Oman 12
TT - Trinidad e Tobago 12
SK - Slovacchia (Repubblica Slovacca) 11
AL - Albania 10
ET - Etiopia 10
EU - Europa 10
HN - Honduras 10
IR - Iran 10
LB - Libano 10
RO - Romania 10
CH - Svizzera 9
DZ - Algeria 9
KG - Kirghizistan 9
PT - Portogallo 9
GR - Grecia 8
HR - Croazia 8
KZ - Kazakistan 8
LV - Lettonia 8
MN - Mongolia 8
PS - Palestinian Territory 8
BG - Bulgaria 7
DO - Repubblica Dominicana 7
BY - Bielorussia 6
GT - Guatemala 6
PA - Panama 6
AO - Angola 5
BH - Bahrain 5
HU - Ungheria 5
NI - Nicaragua 5
SV - El Salvador 5
GA - Gabon 4
MD - Moldavia 4
RS - Serbia 4
SN - Senegal 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BA - Bosnia-Erzegovina 3
CI - Costa d'Avorio 3
DK - Danimarca 3
GE - Georgia 3
KH - Cambogia 3
Totale 54.715
Città #
Helsinki 3.919
Singapore 3.144
Ashburn 2.776
Fairfield 2.522
Woodbridge 2.398
San Jose 1.593
Houston 1.573
Jacksonville 1.393
Chandler 1.308
Ann Arbor 1.234
Hong Kong 1.178
Dallas 1.122
Santa Clara 1.102
Beijing 1.076
Seattle 914
Wilmington 846
Cambridge 763
Izmir 473
Nanjing 436
Ho Chi Minh City 432
Los Angeles 365
Hanoi 318
Princeton 315
New York 267
Council Bluffs 263
Boardman 256
Ferrara 244
Lauterbourg 240
Munich 233
San Diego 229
Tokyo 229
Shanghai 164
São Paulo 162
Warsaw 162
Shenyang 146
Milan 142
Hefei 127
Mexico City 126
Nanchang 121
Orem 112
London 111
Tianjin 102
Bremen 101
Brooklyn 91
Changsha 87
Falkenstein 87
Hebei 85
San Mateo 80
Chicago 78
Jiaxing 77
Turku 75
Frankfurt am Main 70
Montreal 70
Toronto 68
Brussels 67
The Dalles 65
Buffalo 64
Jakarta 64
Atlanta 63
Dong Ket 62
Rio de Janeiro 62
Moscow 61
Phoenix 60
Chennai 57
Da Nang 57
Philadelphia 57
Denver 54
Johannesburg 54
Haiphong 52
Jinan 51
Norwalk 48
Baghdad 46
Stockholm 46
Zhengzhou 46
Kunming 45
Amsterdam 44
Falls Church 44
Dearborn 43
Addison 42
Mountain View 42
San Francisco 42
Boston 41
Guangzhou 41
Manchester 39
Tashkent 38
Brasília 37
Redwood City 35
Paris 34
Orange 33
Mumbai 32
Belo Horizonte 31
Des Moines 31
Quito 31
Hải Dương 30
Medellín 30
Poplar 30
Washington 30
Ankara 29
Curitiba 28
Indiana 27
Totale 37.670
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.103
Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale Distamicina A 1.969
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 531
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 325
A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion 303
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 303
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 298
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition 296
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 292
A3 adenosine receptor antagonists: History and future perspectives 289
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 284
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 281
A one-pot synthesis of nitrohydroxylated pyrrolidine and piperidine ring systems by tandem Michael-Henry reaction 268
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 268
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 267
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 266
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 264
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 264
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 264
Allosteric modulators for the A1-adenosine receptor 258
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 258
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 254
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders 254
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 252
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 251
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity 247
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 247
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 246
Fragment-based discovery of novel small molecule targeting human BAG3 244
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 244
DNA minor groove binders as potential antitumor and antimicrobial agents 242
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 242
Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology 241
Allosteric enhancers for A(1) adenosine receptor 241
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 241
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 241
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 241
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 240
2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization 239
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 235
Mastering β-Keto Esters 235
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 231
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 230
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 229
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 228
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 228
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 226
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 226
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 224
Hybrid molecules between distamycin A and active moieties of antitumor agents 224
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 223
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 223
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 223
Current status of A1 adenosine receptor allosteric enhancers 222
Hybrid molecules based on distamycin A as potential antitumor agents 222
A Facile Synthesis of Diaryl Pyrroles Led to the Discovery of Potent Colchicine Site Antimitotic Agents 221
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 220
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 218
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 216
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 216
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 216
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 215
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 215
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 214
Novel combretastatin analogues endowed with antitumor activity 213
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 212
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 212
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 212
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 211
A new synthetic approach to indazole synthesis 211
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 210
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 210
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 210
2-aminothiophene-3-carboxylic acid ester derivatives as novel highly selective cytostatic agents 210
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 209
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 209
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 208
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 208
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 207
A new synthetic approach to pyrazolo[3,4-c]-1,2,5-oxadiazoles 206
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 205
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 203
Recent developments in the field of adenosine receptor ligands. 202
[3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 202
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 200
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 199
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 198
Recent improvements in the development of A2B adenosine receptor agonists 198
[3H]MRE3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 196
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 194
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 193
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 193
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 193
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors 193
7-sobstituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonist: importance of modifications at the side chain on the activity and solubility. 192
Recent improvements in the development of A2B adenosine receptor agonists 190
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 189
Synthesis, radiolabeling, and preliminary biological evaluation of [H-3]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl )-piperazine, a potent antagonist radioligand for the P2X(7) receptor 186
Allosteric modulators of the A1 adenosine receptor 186
New strategies for the synthesis of A(3) adenosine receptor antagonists 186
Totale 27.894
Categoria #
all - tutte 222.329
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.078
Totale 223.407


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.062 116 307 271 154 169 131 143 142 100 238 329 962
2022/20232.979 318 175 74 421 526 456 91 265 388 17 158 90
2023/20241.656 148 197 84 38 110 197 67 360 24 17 43 371
2024/20256.037 119 199 487 240 726 540 165 377 935 683 817 749
2025/202621.929 1.703 979 2.080 2.228 2.421 1.199 2.004 882 5.318 2.057 792 266
2026/2027520 520 0 0 0 0 0 0 0 0 0 0 0
Totale 55.109