ROMAGNOLI, Romeo
 Distribuzione geografica
Continente #
NA - Nord America 17.933
EU - Europa 5.336
AS - Asia 3.298
SA - Sud America 19
Continente sconosciuto - Info sul continente non disponibili 13
OC - Oceania 7
AF - Africa 4
Totale 26.610
Nazione #
US - Stati Uniti d'America 17.916
CN - Cina 1.919
DE - Germania 1.661
UA - Ucraina 1.240
TR - Turchia 866
GB - Regno Unito 570
IT - Italia 558
SE - Svezia 445
SG - Singapore 349
RU - Federazione Russa 287
FI - Finlandia 275
PL - Polonia 90
FR - Francia 84
VN - Vietnam 63
BE - Belgio 45
HK - Hong Kong 22
ES - Italia 18
IN - India 17
CZ - Repubblica Ceca 16
KR - Corea 15
ID - Indonesia 14
NL - Olanda 13
CA - Canada 11
EU - Europa 10
CO - Colombia 9
JP - Giappone 9
IR - Iran 8
AU - Australia 6
MX - Messico 6
AT - Austria 5
BR - Brasile 5
CL - Cile 5
PT - Portogallo 4
A2 - ???statistics.table.value.countryCode.A2??? 3
EG - Egitto 3
GR - Grecia 3
IL - Israele 3
LT - Lituania 3
BG - Bulgaria 2
CH - Svizzera 2
HR - Croazia 2
IE - Irlanda 2
MD - Moldavia 2
PK - Pakistan 2
RO - Romania 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
AF - Afghanistan, Repubblica islamica di 1
BD - Bangladesh 1
GE - Georgia 1
HU - Ungheria 1
IM - Isola di Man 1
KH - Cambogia 1
LK - Sri Lanka 1
MC - Monaco 1
ME - Montenegro 1
MN - Mongolia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
RS - Serbia 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
Totale 26.610
Città #
Fairfield 2.520
Woodbridge 2.398
Houston 1.540
Ashburn 1.404
Jacksonville 1.381
Chandler 1.308
Ann Arbor 1.234
Seattle 897
Wilmington 845
Cambridge 762
Izmir 468
Nanjing 433
Beijing 369
Princeton 313
Boardman 252
San Diego 226
Ferrara 220
Singapore 207
Shanghai 146
Shenyang 146
Milan 125
Nanchang 121
Bremen 101
Los Angeles 99
Warsaw 87
Hebei 85
Changsha 83
San Mateo 80
New York 78
Jiaxing 77
Tianjin 73
Dong Ket 62
Jinan 50
Norwalk 48
Philadelphia 46
Zhengzhou 45
Brussels 44
Falls Church 44
Dearborn 43
Kunming 43
Addison 42
Mountain View 42
London 40
Redwood City 35
Orange 33
Indiana 27
Paris 25
Guangzhou 24
Washington 24
Auburn Hills 23
Ningbo 23
Taizhou 21
Des Moines 20
Hong Kong 20
Tappahannock 20
Chicago 19
Munich 19
Verona 18
Helsinki 16
Jakarta 13
Lanzhou 13
Redmond 12
Hangzhou 11
Bari 10
Haikou 10
Kilburn 10
Brno 9
Otura 9
Augusta 8
Düsseldorf 8
Leawood 8
Amsterdam 7
Fuzhou 7
Mcallen 7
Olomouc 7
Bologna 6
Medellín 6
Monmouth Junction 6
Montréal 6
Prescot 6
Xian 6
Acton 5
Camerino 5
Changchun 5
Yellow Springs 5
Ferrara di Monte Baldo 4
Hefei 4
Wandsworth 4
Chiswick 3
Chongqing 3
Clifton 3
Florence 3
Hounslow 3
Motril 3
Mysore 3
New Bedfont 3
Padova 3
Perivale 3
Saint Petersburg 3
San Francisco 3
Totale 19.247
Nome #
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 354
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 323
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 162
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity. 161
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 160
A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion 156
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 153
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 150
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 145
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 145
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 143
Design, Synthesis, DNA Binding, and Biological Evaluation of Water-Soluble Hybrid Molecules Containing Two Pyrazole Analogues of the Alkylating Cyclopropylpyrroloindole (CPI) Subunit of the Antitumor Agent CC-1065 and Polypyrrole Minor Groove Binders. 141
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 141
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition 140
Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology 139
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 139
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 139
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 139
Current status of A1 adenosine receptor allosteric enhancers 138
A one-pot synthesis of nitrohydroxylated pyrrolidine and piperidine ring systems by tandem Michael-Henry reaction 137
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 137
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 137
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 135
2-Arylamino-4-Amino-5-Aroylthiazoles. "One-Pot" Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization. 135
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 135
DNA minor groove binders as potential antitumor and antimicrobial agents 134
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 134
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 134
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 133
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 132
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 132
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 131
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 131
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 130
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 130
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 130
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 130
Hybrid molecules based on distamycin A as potential antitumor agents 129
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 129
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 128
Allosteric modulators for the A1-adenosine receptor 127
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 127
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 127
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 126
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 125
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 125
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 124
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 124
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 124
Synthesis and antitumor activity of novel distamycin derivatives 123
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 123
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 122
MASTERING BETA-KETO-ESTERS 122
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 122
null 121
Recent improvements in the development of A2B adenosine receptor agonists. 121
null 121
A3 adenosine receptor antagonists: History and future perspectives 121
null 120
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 119
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 119
N-arylpiperazine modified analogues of the P2X(7) receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts 118
null 118
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 118
Allosteric Modulators of the A1 Adenosine receptor 117
Allosteric modulation of A1-adenosine receptor: A review 116
Synthesis of melodienone and 7-hydroxy-6-hydromelodienone, two heptenes from Melodorum Fruticosum 116
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 115
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 115
DNA minor groove alkylating agents structurally related to distamycin A 114
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 114
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 114
Synthesis, radiolabeling, and preliminary biological evaluation of [H-3]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl )-piperazine, a potent antagonist radioligand for the P2X(7) receptor 114
Design, synthesis and biological activity of 5-fluorouracil-distamycin hybrids 114
Total synthesis of (+/-)-epibatidine 114
Allosteric enhancers for A(1) adenosine receptor 113
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 113
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 113
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 113
null 112
Hybrid molecules between distamycin A and active moieties of antitumor agents 112
New potent and selective human adenosine A3 receptor antagonists. 112
Synthesis and biological evaluation of a series of 2-(3,4,5-trimethoxybenzoyl)-indol-3-yl acetic acid derivatives as potential agents against human leukemia K562 cells 111
Recent improvements in the development of A2B adenosine receptor agonists 111
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 111
Enantiodivergent synthesis of 2-hydroxymethyl-3-hydroxy-4-nitro-pyrrolidines through tandem Michael-Henry reaction using L-serine as the chiral educt 110
null 110
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 110
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. 110
Allosteric modulators of the A1 adenosine receptor 110
A new synthetic approach to indazole synthesis 110
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 110
null 109
Synthesis, biological activity and molecular modeling studies of 1,2,3,4-tetrahydroisoquinoline derivatives as conformationally constrained analogues of KN62, a potent antagonist of the P2X(7)-receptor containing a tyrosine moiety 108
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5- (3′,4′,5′-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent 108
Benzoyl and cinnamoyl nitrogen mustard derivatives of benzoheterocyclic analogues of the tallimustine: Synthesis and antitumour activity 106
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 106
2-aminothiophene-3-carboxylic acid ester derivatives as novel highly selective cytostatic agents 105
Design, synthesis and biological activity of a pyrrolo[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid 104
Selective binding to human genomic sequences of two synthetic analogues structurally related to U-71184 and adozelesin 104
Totale 12.892
Categoria #
all - tutte 104.694
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 498
Totale 105.192


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20204.685 0 202 186 814 392 630 464 548 436 604 301 108
2020/20213.815 372 342 196 420 153 361 112 472 87 527 459 314
2021/20223.062 116 307 271 154 169 131 143 142 100 238 329 962
2022/20232.979 318 175 74 421 526 456 91 265 388 17 158 90
2023/20241.656 148 197 84 38 110 197 67 360 24 17 43 371
2024/2025296 119 177 0 0 0 0 0 0 0 0 0 0
Totale 26.919