ROMAGNOLI, Romeo
 Distribuzione geografica
Continente #
NA - Nord America 19.094
EU - Europa 5.566
AS - Asia 3.869
SA - Sud America 44
Continente sconosciuto - Info sul continente non disponibili 13
OC - Oceania 8
AF - Africa 6
Totale 28.600
Nazione #
US - Stati Uniti d'America 19.041
CN - Cina 1.966
DE - Germania 1.722
UA - Ucraina 1.240
TR - Turchia 867
SG - Singapore 820
GB - Regno Unito 597
IT - Italia 583
SE - Svezia 445
FI - Finlandia 346
RU - Federazione Russa 287
PL - Polonia 90
FR - Francia 84
BE - Belgio 67
VN - Vietnam 63
CA - Canada 47
ID - Indonesia 46
BR - Brasile 29
HK - Hong Kong 23
IN - India 21
NL - Olanda 20
ES - Italia 19
LT - Lituania 17
CZ - Repubblica Ceca 16
KR - Corea 15
EU - Europa 10
JP - Giappone 10
CO - Colombia 9
PK - Pakistan 9
IR - Iran 8
AU - Australia 7
AT - Austria 6
MX - Messico 6
CL - Cile 5
PT - Portogallo 4
A2 - ???statistics.table.value.countryCode.A2??? 3
EG - Egitto 3
GR - Grecia 3
HR - Croazia 3
IL - Israele 3
AE - Emirati Arabi Uniti 2
BG - Bulgaria 2
CH - Svizzera 2
IE - Irlanda 2
MD - Moldavia 2
RO - Romania 2
TN - Tunisia 2
TW - Taiwan 2
AF - Afghanistan, Repubblica islamica di 1
BD - Bangladesh 1
GE - Georgia 1
HU - Ungheria 1
IM - Isola di Man 1
IQ - Iraq 1
JO - Giordania 1
KH - Cambogia 1
LK - Sri Lanka 1
MC - Monaco 1
ME - Montenegro 1
MN - Mongolia 1
MY - Malesia 1
NO - Norvegia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PS - Palestinian Territory 1
RS - Serbia 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 28.600
Città #
Fairfield 2.520
Woodbridge 2.398
Houston 1.540
Ashburn 1.408
Jacksonville 1.381
Chandler 1.308
Ann Arbor 1.234
Seattle 897
Santa Clara 888
Wilmington 845
Cambridge 762
Singapore 641
Izmir 468
Nanjing 433
Beijing 369
Princeton 313
Boardman 252
Ferrara 227
San Diego 226
Shanghai 149
Shenyang 146
Milan 126
Nanchang 121
Bremen 101
Los Angeles 100
Warsaw 87
Hebei 85
Changsha 84
San Mateo 80
New York 78
Jiaxing 77
Helsinki 76
Tianjin 73
Brussels 66
Dong Ket 62
London 56
Jinan 51
Norwalk 48
Philadelphia 46
Jakarta 45
Zhengzhou 45
Falls Church 44
Dearborn 43
Kunming 43
Addison 42
Mountain View 42
Munich 42
Redwood City 35
Orange 33
Indiana 27
Guangzhou 26
Paris 25
Washington 25
Auburn Hills 23
Ningbo 23
Toronto 23
Taizhou 22
Hong Kong 21
Des Moines 20
Tappahannock 20
Chicago 19
Frankfurt am Main 19
Verona 18
Falkenstein 17
Ottawa 15
Lanzhou 13
Redmond 12
Hangzhou 11
Bari 10
Espoo 10
Haikou 10
Kilburn 10
Amsterdam 9
Brno 9
Otura 9
Augusta 8
Düsseldorf 8
Leawood 8
Fuzhou 7
Mcallen 7
Olomouc 7
Bologna 6
Changchun 6
Medellín 6
Monmouth Junction 6
Montréal 6
Prescot 6
Taunsa 6
Xian 6
Acton 5
Camerino 5
Chongqing 5
Yellow Springs 5
Chandigarh 4
Ferrara di Monte Baldo 4
Hefei 4
Vienna 4
Wandsworth 4
Chiswick 3
Clifton 3
Totale 20.821
Nome #
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 367
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 342
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 171
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 169
A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion 168
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity. 167
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 165
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 161
A3 adenosine receptor antagonists: History and future perspectives 158
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 155
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 154
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 153
Design, Synthesis, DNA Binding, and Biological Evaluation of Water-Soluble Hybrid Molecules Containing Two Pyrazole Analogues of the Alkylating Cyclopropylpyrroloindole (CPI) Subunit of the Antitumor Agent CC-1065 and Polypyrrole Minor Groove Binders. 152
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 152
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 150
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 150
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 149
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition 149
DNA minor groove binders as potential antitumor and antimicrobial agents 148
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 148
A one-pot synthesis of nitrohydroxylated pyrrolidine and piperidine ring systems by tandem Michael-Henry reaction 147
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 147
Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology 146
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 146
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 146
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 145
Current status of A1 adenosine receptor allosteric enhancers 143
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 143
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 143
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 142
2-Arylamino-4-Amino-5-Aroylthiazoles. "One-Pot" Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization. 142
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 141
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 141
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 141
Hybrid molecules based on distamycin A as potential antitumor agents 141
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 140
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 139
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 138
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 137
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 137
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 137
Allosteric modulators for the A1-adenosine receptor 137
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 137
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 136
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 135
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 135
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 135
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 133
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 133
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 133
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 132
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 132
MASTERING BETA-KETO-ESTERS 131
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 130
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 130
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 129
Recent improvements in the development of A2B adenosine receptor agonists. 129
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 128
Synthesis and antitumor activity of novel distamycin derivatives 127
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 127
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 127
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 124
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 124
Allosteric enhancers for A(1) adenosine receptor 123
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 123
N-arylpiperazine modified analogues of the P2X(7) receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts 122
Allosteric Modulators of the A1 Adenosine receptor 122
Hybrid molecules between distamycin A and active moieties of antitumor agents 122
New potent and selective human adenosine A3 receptor antagonists. 122
null 121
null 121
Synthesis, radiolabeling, and preliminary biological evaluation of [H-3]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl )-piperazine, a potent antagonist radioligand for the P2X(7) receptor 120
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 120
Allosteric modulation of A1-adenosine receptor: A review 120
null 120
Synthesis of melodienone and 7-hydroxy-6-hydromelodienone, two heptenes from Melodorum Fruticosum 120
Design, synthesis and biological activity of 5-fluorouracil-distamycin hybrids 119
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 119
DNA minor groove alkylating agents structurally related to distamycin A 118
Benzoyl and cinnamoyl nitrogen mustard derivatives of benzoheterocyclic analogues of the tallimustine: Synthesis and antitumour activity 118
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 118
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. 118
A new synthetic approach to indazole synthesis 118
null 118
Total synthesis of (+/-)-epibatidine 118
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 117
Recent improvements in the development of A2B adenosine receptor agonists 117
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 116
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 116
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 116
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 115
Synthesis and biological evaluation of a series of 2-(3,4,5-trimethoxybenzoyl)-indol-3-yl acetic acid derivatives as potential agents against human leukemia K562 cells 115
Synthesis, biological activity and molecular modeling studies of 1,2,3,4-tetrahydroisoquinoline derivatives as conformationally constrained analogues of KN62, a potent antagonist of the P2X(7)-receptor containing a tyrosine moiety 114
Enantiodivergent synthesis of 2-hydroxymethyl-3-hydroxy-4-nitro-pyrrolidines through tandem Michael-Henry reaction using L-serine as the chiral educt 114
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked heterocycles as template for the adenosine receptor antagonism: medicinal chemistry approach and SAR considerations. 114
Allosteric modulators of the A1 adenosine receptor 113
null 112
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5- (3′,4′,5′-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent 112
Recent developments in the field of adenosine receptor ligands. 111
Design, Synthesis and Biological Evaluation of Arylcinnamide Hybrid Derivatives as Novel Anticancer Agents 111
Totale 13.747
Categoria #
all - tutte 125.072
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 654
Totale 125.726


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20203.091 0 0 0 0 0 630 464 548 436 604 301 108
2020/20213.815 372 342 196 420 153 361 112 472 87 527 459 314
2021/20223.062 116 307 271 154 169 131 143 142 100 238 329 962
2022/20232.979 318 175 74 421 526 456 91 265 388 17 158 90
2023/20241.656 148 197 84 38 110 197 67 360 24 17 43 371
2024/20252.293 119 199 487 240 726 522 0 0 0 0 0 0
Totale 28.916