PACIFICO, Salvatore
 Distribuzione geografica
Continente #
NA - Nord America 3.240
EU - Europa 1.022
AS - Asia 606
SA - Sud America 13
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 4.887
Nazione #
US - Stati Uniti d'America 3.232
IT - Italia 372
PL - Polonia 246
CN - Cina 239
SG - Singapore 190
UA - Ucraina 89
TR - Turchia 86
DE - Germania 73
GB - Regno Unito 64
ID - Indonesia 57
SE - Svezia 43
IE - Irlanda 42
FI - Finlandia 28
BE - Belgio 23
VN - Vietnam 15
CZ - Repubblica Ceca 14
CA - Canada 7
BR - Brasile 6
FR - Francia 6
IN - India 5
LT - Lituania 5
RU - Federazione Russa 4
EU - Europa 3
HK - Hong Kong 3
IR - Iran 3
PE - Perù 3
AR - Argentina 2
AT - Austria 2
AU - Australia 2
CL - Cile 2
JP - Giappone 2
NL - Olanda 2
RO - Romania 2
BG - Bulgaria 1
BS - Bahamas 1
CH - Svizzera 1
DK - Danimarca 1
ES - Italia 1
GR - Grecia 1
IL - Israele 1
KR - Corea 1
KW - Kuwait 1
MK - Macedonia 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PK - Pakistan 1
PT - Portogallo 1
SA - Arabia Saudita 1
Totale 4.887
Città #
Fairfield 480
Woodbridge 374
Ashburn 260
Warsaw 246
Ann Arbor 241
Houston 218
Chandler 212
Ferrara 200
Seattle 188
Cambridge 177
Wilmington 154
Singapore 149
Jacksonville 119
Menlo Park 98
Jakarta 57
Beijing 56
New York 55
Princeton 55
Shanghai 47
Izmir 44
Nanjing 41
Los Angeles 38
Milan 35
San Diego 28
Addison 24
Brussels 23
Nanchang 20
Boardman 19
Dearborn 18
Santa Clara 17
Dong Ket 15
London 14
Bologna 13
Ferrara di Monte Baldo 13
Munich 13
Redwood City 13
St Louis 12
Mountain View 11
Brno 10
Falls Church 10
Bremen 9
Norwalk 9
Des Moines 8
Helsinki 8
Padova 8
Cagliari 7
Jinan 7
Rome 7
San Mateo 7
Shenyang 7
Changsha 6
Washington 6
Hebei 5
Jiaxing 5
Auburn Hills 4
Dublin 4
Frankfurt am Main 4
Grassano 4
Guangzhou 4
Ningbo 4
Olomouc 4
Bari 3
Bournemouth 3
Hefei 3
Leawood 3
Lima 3
Orange 3
Tappahannock 3
Tianjin 3
Toronto 3
Waban 3
Ardabil 2
Aversa 2
Buenos Aires 2
Chicago 2
Clifton 2
Florence 2
Fort Huachuca 2
Haikou 2
Hong Kong 2
Hyderabad 2
Islington 2
Kunming 2
La Canada Flintridge 2
Lanzhou 2
Lugo 2
Minneapolis 2
Modena 2
Montreal 2
Ottawa 2
Pozzo 2
Prescot 2
Springfield 2
São Paulo 2
Torino 2
Turin 2
Walnut 2
Acton 1
Albert Park 1
Athens 1
Totale 4.029
Nome #
Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer’s disease 224
Sintesi di glicopeptidi mediante le reazioni tiol-ene/ino e studio della reattività di Umpolung di α-dichetoni 196
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 174
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 159
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones 154
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 140
Photoinduced addition of glycosyl thiols to alkynyl peptides: use of free-radical thiol-yne coupling for post-translational double-glycosylation of peptides 137
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 136
Modulation of the NOP receptor signaling affects resilience to acute stress 132
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 128
One-pot, two-step desymmetrization of symmetrical benzils catalyzed by the methylsulfinyl (dimsyl) anion 128
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones 126
Synthesis of S-glycosyl amino acids and S-glycopeptides via photoinduced click thiol-ene coupling 114
null 110
null 108
Neuropeptide S receptor ligands: a patent review (2005-2016) 107
Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology 106
Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation 105
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 105
Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor 104
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles 102
Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? 99
Peptide welding technology – A simple strategy for generating innovative ligands for G protein coupled receptors 99
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 97
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 96
null 94
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 94
null 92
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 91
Fluorometric detection of protein-ligand engagement: The case of phosphodiesterase5 84
alpha-Diketones as acyl anion equivalents: a non-enzymatic thiamine-promoted route to aldehyde ketone coupling in PEG(400) as recyclable medium 83
null 79
The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation 79
Thiazolium-catalyzed intermolecular Stetter reaction of linear and cyclic alkyl α-diketones 77
Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease 77
alpha-Diketones as acyl anion equivalents: new enzymatic and non-enzymatic thiamine-promoted routes to aldehyde-ketone coupling 73
Synthesis of folic acid functionalized gold nanoclusters for targeting folate receptor-positive cells 61
null 57
Reactivity of dialkyl and diaryl alpha-diketones with N-heterocyclic carbenes 55
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 52
Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders 50
Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects 47
Novel Mixed NOP/Opioid Receptor Peptide Agonists 44
Use of a Novel Peptide Welding Technology Platform for the Development of B- and T-Cell Epitope-Based Vaccines 42
Probing the Effect of Sildenafil on Progesterone and Testosterone Production by an Intracellular FRET/BRET Combined Approach 41
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 40
Cyclic peptides acting as allosteric inhibitors of human thymidylate synthase and cancer cell growth 36
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists 36
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 35
Ageing Curtails the Diversity and Functionality of Nascent CD8+ T Cell Responses against SARS-CoV-2 34
Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase 32
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative 30
Thermodynamic Stability and Speciation of Ga(III) and Zr(IV) Complexes with High-Denticity Hydroxamate Chelators 30
Serum beta-secretase 1 (BACE1) activity increases in patients with mild cognitive impairment 25
Dimethyl Sulfoxide and N,N-dimethylformamide as Umpolung Pre-catalysts in Cross Benzoin Reactions of alpha-Diketones with Aldehydes 24
Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease 24
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells 22
Unexpected reactivity of diaryl α-diketones with thiazolium carbenes: discovery of a novel multicomponent reaction for the facile synthesis of 1,4-thiazin-3-ones 20
Methylsulfinyl (Dimsyl) Anion as Umpolung Catalyst for the Chemoselective Cross Benzoin Reaction of α-Diketones with Aldehydes 20
Thiazolium-Functionalized Polystyrene Monolithic Microreactors for Continuous-Flow Umpolung Catalysis 16
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 16
Phosphodiesterase (PDE) 5 inhibitors sildenafil, tadalafil and vardenafil impact cAMP-specific PDE8 isoforms-linked second messengers and steroid production in a mouse Leydig tumor cell line 16
Thiazolium-functionalized polystyrene monolithic microreactors for continuous-flow umpolung catalysis 15
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications 12
Synthesis of Chiral Ionic Liquids from Natural Monosaccharides 7
Totale 5.048
Categoria #
all - tutte 27.507
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.507


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020673 0 0 0 0 72 117 122 101 104 72 50 35
2020/20211.027 47 104 47 74 73 93 92 115 46 178 76 82
2021/2022690 31 91 147 32 27 33 43 26 33 51 34 142
2022/2023522 57 61 12 60 73 53 49 45 55 3 39 15
2023/2024481 50 47 24 25 25 81 25 47 22 24 14 97
2024/2025396 67 38 160 96 35 0 0 0 0 0 0 0
Totale 5.048