PACIFICO, Salvatore
 Distribuzione geografica
Continente #
NA - Nord America 3.358
EU - Europa 1.023
AS - Asia 608
SA - Sud America 13
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 5.008
Nazione #
US - Stati Uniti d'America 3.350
IT - Italia 373
PL - Polonia 246
CN - Cina 239
SG - Singapore 192
UA - Ucraina 89
TR - Turchia 86
DE - Germania 73
GB - Regno Unito 64
ID - Indonesia 57
SE - Svezia 43
IE - Irlanda 42
FI - Finlandia 28
BE - Belgio 23
VN - Vietnam 15
CZ - Repubblica Ceca 14
CA - Canada 7
BR - Brasile 6
FR - Francia 6
IN - India 5
LT - Lituania 5
RU - Federazione Russa 4
EU - Europa 3
HK - Hong Kong 3
IR - Iran 3
PE - Perù 3
AR - Argentina 2
AT - Austria 2
AU - Australia 2
CL - Cile 2
JP - Giappone 2
NL - Olanda 2
RO - Romania 2
BG - Bulgaria 1
BS - Bahamas 1
CH - Svizzera 1
DK - Danimarca 1
ES - Italia 1
GR - Grecia 1
IL - Israele 1
KR - Corea 1
KW - Kuwait 1
MK - Macedonia 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PK - Pakistan 1
PT - Portogallo 1
SA - Arabia Saudita 1
Totale 5.008
Città #
Fairfield 480
Woodbridge 374
Ashburn 260
Warsaw 246
Ann Arbor 241
Houston 218
Chandler 212
Ferrara 200
Seattle 188
Cambridge 177
Wilmington 154
Singapore 151
Santa Clara 130
Jacksonville 119
Menlo Park 98
Jakarta 57
Beijing 56
New York 55
Princeton 55
Shanghai 47
Izmir 44
Nanjing 41
Los Angeles 38
Milan 35
San Diego 28
Addison 24
Brussels 23
Nanchang 20
Boardman 19
Dearborn 18
Dong Ket 15
Bologna 14
London 14
Ferrara di Monte Baldo 13
Munich 13
Redwood City 13
St Louis 12
Mountain View 11
Brno 10
Falls Church 10
Bremen 9
Norwalk 9
Des Moines 8
Helsinki 8
Padova 8
Cagliari 7
Jinan 7
Rome 7
San Mateo 7
Shenyang 7
Changsha 6
Washington 6
Hebei 5
Jiaxing 5
Auburn Hills 4
Dublin 4
Frankfurt am Main 4
Grassano 4
Guangzhou 4
Ningbo 4
Olomouc 4
Bari 3
Bournemouth 3
Hefei 3
Leawood 3
Lima 3
Orange 3
Tappahannock 3
Tianjin 3
Toronto 3
Waban 3
Ardabil 2
Aversa 2
Buenos Aires 2
Chicago 2
Clifton 2
Florence 2
Fort Huachuca 2
Haikou 2
Hong Kong 2
Hyderabad 2
Islington 2
Kunming 2
La Canada Flintridge 2
Lanzhou 2
Lugo 2
Minneapolis 2
Modena 2
Montreal 2
Ottawa 2
Pozzo 2
Prescot 2
Springfield 2
São Paulo 2
Torino 2
Turin 2
Walnut 2
Acton 1
Albert Park 1
Athens 1
Totale 4.145
Nome #
Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer’s disease 227
Sintesi di glicopeptidi mediante le reazioni tiol-ene/ino e studio della reattività di Umpolung di α-dichetoni 198
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 175
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 161
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones 157
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 142
Photoinduced addition of glycosyl thiols to alkynyl peptides: use of free-radical thiol-yne coupling for post-translational double-glycosylation of peptides 139
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 138
Modulation of the NOP receptor signaling affects resilience to acute stress 134
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 130
One-pot, two-step desymmetrization of symmetrical benzils catalyzed by the methylsulfinyl (dimsyl) anion 130
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones 128
Synthesis of S-glycosyl amino acids and S-glycopeptides via photoinduced click thiol-ene coupling 116
null 110
Neuropeptide S receptor ligands: a patent review (2005-2016) 109
null 108
Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology 108
Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation 107
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 107
Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor 106
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles 104
Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? 101
Peptide welding technology – A simple strategy for generating innovative ligands for G protein coupled receptors 101
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 99
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 98
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 97
null 94
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 93
null 92
alpha-Diketones as acyl anion equivalents: a non-enzymatic thiamine-promoted route to aldehyde ketone coupling in PEG(400) as recyclable medium 86
Fluorometric detection of protein-ligand engagement: The case of phosphodiesterase5 86
The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation 81
Thiazolium-catalyzed intermolecular Stetter reaction of linear and cyclic alkyl α-diketones 79
null 79
Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease 79
alpha-Diketones as acyl anion equivalents: new enzymatic and non-enzymatic thiamine-promoted routes to aldehyde-ketone coupling 75
Synthesis of folic acid functionalized gold nanoclusters for targeting folate receptor-positive cells 63
Reactivity of dialkyl and diaryl alpha-diketones with N-heterocyclic carbenes 57
null 57
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 54
Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders 52
Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects 49
Novel Mixed NOP/Opioid Receptor Peptide Agonists 45
Use of a Novel Peptide Welding Technology Platform for the Development of B- and T-Cell Epitope-Based Vaccines 44
Probing the Effect of Sildenafil on Progesterone and Testosterone Production by an Intracellular FRET/BRET Combined Approach 43
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 42
Cyclic peptides acting as allosteric inhibitors of human thymidylate synthase and cancer cell growth 38
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists 38
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 37
Ageing Curtails the Diversity and Functionality of Nascent CD8+ T Cell Responses against SARS-CoV-2 36
Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase 34
Thermodynamic Stability and Speciation of Ga(III) and Zr(IV) Complexes with High-Denticity Hydroxamate Chelators 32
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative 31
Serum beta-secretase 1 (BACE1) activity increases in patients with mild cognitive impairment 28
Dimethyl Sulfoxide and N,N-dimethylformamide as Umpolung Pre-catalysts in Cross Benzoin Reactions of alpha-Diketones with Aldehydes 26
Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease 25
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells 24
Unexpected reactivity of diaryl α-diketones with thiazolium carbenes: discovery of a novel multicomponent reaction for the facile synthesis of 1,4-thiazin-3-ones 23
Methylsulfinyl (Dimsyl) Anion as Umpolung Catalyst for the Chemoselective Cross Benzoin Reaction of α-Diketones with Aldehydes 22
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 19
Thiazolium-Functionalized Polystyrene Monolithic Microreactors for Continuous-Flow Umpolung Catalysis 18
Phosphodiesterase (PDE) 5 inhibitors sildenafil, tadalafil and vardenafil impact cAMP-specific PDE8 isoforms-linked second messengers and steroid production in a mouse Leydig tumor cell line 18
Thiazolium-functionalized polystyrene monolithic microreactors for continuous-flow umpolung catalysis 17
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications 14
Synthesis of Chiral Ionic Liquids from Natural Monosaccharides 9
Totale 5.169
Categoria #
all - tutte 28.310
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.310


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020673 0 0 0 0 72 117 122 101 104 72 50 35
2020/20211.027 47 104 47 74 73 93 92 115 46 178 76 82
2021/2022690 31 91 147 32 27 33 43 26 33 51 34 142
2022/2023522 57 61 12 60 73 53 49 45 55 3 39 15
2023/2024481 50 47 24 25 25 81 25 47 22 24 14 97
2024/2025517 67 38 160 96 156 0 0 0 0 0 0 0
Totale 5.169