CACCIARI, Barbara
 Distribuzione geografica
Continente #
NA - Nord America 8.200
EU - Europa 2.027
AS - Asia 1.885
SA - Sud America 77
OC - Oceania 4
AF - Africa 2
Continente sconosciuto - Info sul continente non disponibili 2
Totale 12.197
Nazione #
US - Stati Uniti d'America 8.166
CN - Cina 976
UA - Ucraina 662
TR - Turchia 444
DE - Germania 393
SG - Singapore 326
GB - Regno Unito 275
SE - Svezia 215
IT - Italia 159
FI - Finlandia 156
BR - Brasile 67
VN - Vietnam 62
FR - Francia 39
PL - Polonia 38
CA - Canada 32
HK - Hong Kong 27
RU - Federazione Russa 25
BE - Belgio 21
ID - Indonesia 17
IN - India 12
NL - Olanda 10
LT - Lituania 9
AR - Argentina 4
CZ - Repubblica Ceca 4
IE - Irlanda 4
AT - Austria 3
ES - Italia 3
IQ - Iraq 3
IR - Iran 3
KR - Corea 3
TW - Taiwan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AU - Australia 2
BG - Bulgaria 2
CH - Svizzera 2
NZ - Nuova Zelanda 2
PK - Pakistan 2
UZ - Uzbekistan 2
VE - Venezuela 2
BD - Bangladesh 1
BO - Bolivia 1
BY - Bielorussia 1
CL - Cile 1
CO - Colombia 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
JP - Giappone 1
KZ - Kazakistan 1
LB - Libano 1
MD - Moldavia 1
ME - Montenegro 1
MX - Messico 1
NO - Norvegia 1
PA - Panama 1
PH - Filippine 1
PT - Portogallo 1
RO - Romania 1
SD - Sudan 1
Totale 12.197
Città #
Woodbridge 977
Fairfield 914
Houston 770
Jacksonville 711
Ashburn 660
Chandler 593
Ann Arbor 488
Santa Clara 396
Wilmington 356
Seattle 350
Cambridge 264
Nanjing 243
Singapore 243
Izmir 220
Princeton 158
Boardman 111
Beijing 109
San Diego 89
Shenyang 77
Nanchang 67
Dong Ket 61
Jiaxing 41
Shanghai 41
Milan 40
Ferrara 39
Los Angeles 37
San Mateo 37
Hebei 34
Tianjin 34
Kunming 32
Warsaw 31
Changsha 30
Dearborn 30
Jinan 28
Zhengzhou 27
Falls Church 26
Helsinki 26
Hong Kong 25
Norwalk 22
Brussels 21
Falkenstein 20
Philadelphia 19
Ningbo 18
Addison 17
London 16
Guangzhou 15
Jakarta 15
Munich 15
New York 15
Bremen 14
Mountain View 14
Taizhou 14
Verona 13
Montréal 12
Redwood City 12
Toronto 12
Indiana 11
Washington 11
Augusta 9
Frankfurt am Main 9
Mcallen 9
Orange 9
Auburn Hills 8
Des Moines 8
Redmond 8
São Paulo 8
Tappahannock 7
Bologna 6
Hangzhou 6
Leawood 6
Amsterdam 5
Düsseldorf 5
Haikou 5
Kilburn 5
Ottawa 5
Weihai 5
Chiswick 4
Dublin 4
Hefei 4
Lanzhou 4
Rome 4
San Francisco 4
Yellow Springs 4
Baghdad 3
Berlin 3
Brno 3
Changchun 3
Chicago 3
Ferrara di Monte Baldo 3
Fortaleza 3
Fuzhou 3
Istanbul 3
Las Vegas 3
Monmouth Junction 3
Nantong 3
New Bedfont 3
Senador Canedo 3
Vienna 3
Villafranca Padovana 3
Ardabil 2
Totale 8.922
Nome #
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 370
1,2,3-triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: A new class of A(2A) adenosine receptor antagonists 307
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 177
5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors 161
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 147
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 135
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 134
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and Structurally Simplified Analogs. Chemistry and SAR Profile as Adenosine Receptor Antagonists 132
Synthesis and antitumor activity of novel distamycin derivatives 127
The influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl moiety on the adenosine receptors affinity profile of pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c] pyrimidine derivatives 127
New potent and selective human adenosine A3 receptor antagonists. 122
Synthesis and calcium antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(nitrogenous heteroaryl)-3,5-pyridine dicarboxylates. 120
DNA minor groove alkylating agents structurally related to distamycin A 118
A new synthetic approach to indazole synthesis 118
null 118
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 118
8-(2-Furyl)adenine derivatives as A₂A adenosine receptor ligands 116
Oligonucleotides and oligonucleotide conjugates: A new approach for cancer treatment 115
Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs) 113
Nitrile oxide [3 + 2] cycloaddition: application to the synthesis of 6-substituted 3(2H)-pyridazinones and 6-substituted 4,5-dihydro-4-hydroxy-3(2H)-pyridazinones 111
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A1 adenosine receptor antagonists 111
Resolution of a CPzI precursor, synthesis and biological evaluation of (+) and (-)-N-Boc-CPzI: A further validation of the relationship between chemical solvolytic stability and cytotoxicity 109
DNA minor-groove binders: results and design of new antitumor agents 108
Design, synthesis and biological activity of a pyrrolo[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid 108
Carbon nanotube substrates boost neuronal electrical signaling 108
Structure-activity relationship of novel tallimustine derivatives: Synthesis and antitumor activity 107
Selective binding to human genomic sequences of two synthetic analogues structurally related to U-71184 and adozelesin 107
Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors 106
Antiproliferative effects of novel synthetic nucleobase analogues on U937 Histiocytic lymphoma cell line 106
A2A-adenosine receptor reserve for coronary vasodilation 106
An efficient procedure for the synthesis of 5H-6-substituted-pyrazolo[1,5-d]-1,2,4-triazine-4,7-diones 105
null 104
Synthesis and preliminary biological evaluation of [H-3]-MRE 3008-F20: the first high affinity radioligand antagonist for the human A(3) adenosine receptors 104
Solid lipid microparticles for the stability enhancement of a dopamine prodrug 104
Synthesis and Antitumor Activity of a New Class of Pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone Analogs of Pyrrolo[1,4][2,1-c]benzodiazepines 104
Facile and versatile route to the synthesis of fused 2-pyridones: Useful intermediates for polycyclic sytems 103
Ethyl-(R,S)-5-acetyl-4,5-dihydro-3-isoxazole acetate 102
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 101
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: A complete structure-activity profile 101
Linear and nonlinear 3D-QSAR approaches in tandem with ligand-based homology modeling as a computational strategy to depict the pyrazolo-triazolo- pyrimidine antagonists binding site of the human adenosine A2A receptor 101
Ethyl (R,S)-5-acetyl-4,5-dihydro-3-isoxazoleacetate 101
Schematic overview of oligosaccharides, with survey on their major physiological effects and a focus on milk ones 101
New potent and selective human adenosine A3 receptor antagonists 101
Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c] [1,4]benzodiazepines 99
Chemical synthesis of [13C]daidzein. 98
Synthesis and properties of substituted CBI analogs of CC-1065 and the duocarmycins incorporating the 7-methoxy-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (MCBI) alkylation subunit: Magnitude of electronic effects on the functional reactivity 98
Structure Activity Relationship of 4-Amino-2-thiopyrimidine Derivatives as Platelet Aggregation Inhibitors 98
The Significance of 2-Furyl Ring Substitution with a 2-(para-substituted) Aryl Group in a New Series of Pyrazolo-triazolo-pyrimidines as Potent and Highly Selective hA3 Adenosine Receptors Antagonists: New Insights into Structure-Affinity Relationship and Receptor-Antagonist Recognition 97
1H-pyrazolo[4,3-d]pyrimidine-7(6H)-one and 5H-pyrazolo[4,3-d] 1,2,3-triazin-4(3H)-one derivatives. Synthesis and in vitro biological activity at adenosine A1 and A2a receptors 97
CC-1065 and the duocarmycins: recent developments 96
Synthesis and Biological Evaluation of a New Series of 1,2,4-Triazolo[1,5-a]-1,3,5-triazines as Human A(2A) Adenosine Receptor Antagonists with Improved Water Solubility 96
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 95
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes 95
Exploring Potency and Selectivity Receptor Antagonist Profiles Using a Multilabel Classification Approach: The Human Adenosine Receptors as a Key Study 94
Synthesis of pyridazine derivatives through the unexpected intermediate 5-amino-4-cyano-2,3-dihydro-furan-2,3-disulfonic acid disodium salt 94
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 94
Synthesis, biological studies and molecular modeling investigation of 1,3-dimethyl-2,4-dioxo-6-methyl-8-(substituted) 1,2,3,4-tetrahydro [1,2,4]-triazolo [3,4-f]-purines as potential adenosine receptor antagonists 93
Recent developments in the field of adenosine receptor ligands 92
Cosmetic preservation and structure-activity relationships of 4-diazo-pyrazole-5-carboxamides 92
Demystifying the three dimensional structure of G protein-coupled receptors (GPCRs) with the aid of molecular modeling 92
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 90
null 90
[3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 90
A(3) adenosine receptor ligands: History and perspectives 88
Carbon Nanotubes Carrying Cell-Adhesion Peptides do not Interfere with Neuronal Functionality 88
[3H]MRE3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 88
null 87
7-sobstituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonist: importance of modifications at the side chain on the activity and solubility. 85
Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process 85
Substituted 6-amino-thiouracils as new P2Y(12) receptor antagonists 84
Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors 84
Synthesis and cardiodepressant activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(pentatomic-heteroaryl)-3,5-pyridinedicarboxylates. 2 82
A(1) and A(3) adenosine receptor agonists: an overview 82
Novel N-6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A(3) adenosine receptors 81
Pyrazolo [4,3-E]1,2,4-triazolo[1,5-c]pyrimidine derivates a new class of potent and selective human A3 adenosine receptor antagonists. 81
Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists 78
null 77
Synthesis and Biological Activity of a New Series of N6-Arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-Carboxamido Derivatives of Adenosine-5'-N-ethyluronamide as A1 and A3 Adenosine Receptor Agonists 77
Unusual Ring-Opening Reaction of 6,7-Dihydrothieno[3,2-d]pyrimidine- 2,4-dione Derivatives Leading to 5-(Alkylthio)-6-vinyluracils 76
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]-pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists 75
Synthesis, biological and modeling studies of new water soluble hA3 adenosine receptor antagonists. 74
A2Aadenosine receptor antagonists as therapeutic candidates: Are they still an interesting challenge? 74
Rationale design of new human adenosione A3 receptor antagonists through a CoMFA model. 73
Pyridazine nucleus: a pharmacophoric moiety for bio-active compounds 73
Synthesis, binding and thermodynamic studies of new highly selective A2A adenosine receptor antagonists 73
Synthesis, antibacterial activity and structure-activity relationships of N-substituted 4-diazopyrazole-5-carboxamides. 2 72
Heterocyclic analogs of DNA minor groove alkylating agents 72
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives: Potent and selective A2A adenosine antagonists 72
Synthesis and molecular investigation of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivates as human A3 adenosine receptor antagonists. 71
Synthesis, cytotoxicity and antitumor activity of some new simplified pyrazole analogs of the antitumor agent CC-1065. Effect of an hydrophobic group on antitumor activity 70
Synthesis and molecular investigation of new pyrazolo[4,3-e]1,2,4,-triazolo[1,5-c]pyrimidine derivates as human A3 adenosine receptor antagonists. 70
Comparative molecular field analysis (CoMFA) of a series of selective adenosine receptor A(2A) antagonists 69
Synthesis and biological evaluation of new antitubulin agents containing 2-(30,40,50-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold 67
Triazolo-triazine as new adenosine receptor antagonists. 66
Conjugation of Dopamine and an A2A Adenosine Receptor Antagonist: a possible approach for the treatment of Parkinson’s Disease. 66
Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist 65
Binding affinity of adenosine receptor agonists and antagonists at human A3 adenosine receptors 65
Current developments of A(2a) adenosine receptor antagonists 65
A novel class of pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A3 adenosine receptor antagonists 64
Synthesis and pharmacological characterization of [3H]-MRE3008F20: the first radioligand antagonist for the human A3 adenosine receptors. 63
Totale 10.066
Categoria #
all - tutte 59.315
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 319
Totale 59.634


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020776 0 0 0 0 0 0 0 234 165 265 75 37
2020/20211.641 144 145 112 183 50 167 32 199 36 188 232 153
2021/20221.361 39 138 78 135 85 51 42 83 38 98 153 421
2022/20231.317 158 63 26 171 220 223 31 118 173 8 73 53
2023/2024810 70 92 34 21 71 60 20 260 12 12 10 148
2024/20251.111 75 134 196 79 329 171 55 72 0 0 0 0
Totale 12.317