CACCIARI, Barbara
 Distribuzione geografica
Continente #
NA - Nord America 7.650
EU - Europa 1.918
AS - Asia 1.542
SA - Sud America 6
OC - Oceania 4
AF - Africa 2
Continente sconosciuto - Info sul continente non disponibili 2
Totale 11.124
Nazione #
US - Stati Uniti d'America 7.633
CN - Cina 854
UA - Ucraina 662
TR - Turchia 439
DE - Germania 360
GB - Regno Unito 265
SE - Svezia 215
FI - Finlandia 142
IT - Italia 138
SG - Singapore 130
VN - Vietnam 62
FR - Francia 38
PL - Polonia 38
HK - Hong Kong 25
RU - Federazione Russa 22
CA - Canada 15
BE - Belgio 11
IN - India 11
ID - Indonesia 8
NL - Olanda 7
CZ - Repubblica Ceca 4
BR - Brasile 3
IE - Irlanda 3
IR - Iran 3
KR - Corea 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AT - Austria 2
AU - Australia 2
BG - Bulgaria 2
CH - Svizzera 2
ES - Italia 2
IQ - Iraq 2
NZ - Nuova Zelanda 2
BD - Bangladesh 1
CL - Cile 1
CO - Colombia 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
LB - Libano 1
MD - Moldavia 1
ME - Montenegro 1
MX - Messico 1
PA - Panama 1
PH - Filippine 1
PT - Portogallo 1
RO - Romania 1
SD - Sudan 1
TW - Taiwan 1
UZ - Uzbekistan 1
Totale 11.124
Città #
Woodbridge 977
Fairfield 914
Houston 770
Jacksonville 711
Ashburn 657
Chandler 593
Ann Arbor 488
Wilmington 356
Seattle 350
Cambridge 264
Nanjing 243
Izmir 220
Princeton 158
Boardman 111
Beijing 108
San Diego 89
Shenyang 77
Singapore 70
Nanchang 66
Dong Ket 61
Jiaxing 41
Shanghai 39
Milan 38
San Mateo 37
Hebei 34
Tianjin 34
Ferrara 32
Kunming 32
Warsaw 31
Changsha 30
Dearborn 30
Jinan 27
Zhengzhou 27
Falls Church 26
Hong Kong 24
Norwalk 22
Philadelphia 19
Ningbo 18
Addison 17
New York 15
Bremen 14
Mountain View 14
Munich 13
Taizhou 13
Verona 13
Guangzhou 12
Helsinki 12
Montréal 12
Redwood City 12
Brussels 11
Indiana 11
Washington 11
London 10
Los Angeles 10
Augusta 9
Mcallen 9
Orange 9
Auburn Hills 8
Des Moines 8
Redmond 8
Tappahannock 7
Hangzhou 6
Jakarta 6
Leawood 6
Amsterdam 5
Düsseldorf 5
Haikou 5
Kilburn 5
Chiswick 4
Lanzhou 4
San Francisco 4
Weihai 4
Yellow Springs 4
Brno 3
Changchun 3
Dublin 3
Ferrara di Monte Baldo 3
Fuzhou 3
Hefei 3
Monmouth Junction 3
New Bedfont 3
Villafranca Padovana 3
Ardabil 2
Baghdad 2
Catania 2
Chicago 2
Cosenza 2
Edinburgh 2
Hounslow 2
Las Vegas 2
Misterbianco 2
Mumbai 2
Padova 2
Peterborough 2
Polska 2
Rome 2
Saint Petersburg 2
San Jose 2
Santa Clara 2
Shenzhen 2
Totale 8.203
Nome #
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 354
1,2,3-triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: A new class of A(2A) adenosine receptor antagonists 268
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 162
5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors 148
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 135
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 124
Synthesis and antitumor activity of novel distamycin derivatives 122
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and Structurally Simplified Analogs. Chemistry and SAR Profile as Adenosine Receptor Antagonists 121
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 120
null 118
The influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl moiety on the adenosine receptors affinity profile of pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c] pyrimidine derivatives 118
Synthesis and calcium antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(nitrogenous heteroaryl)-3,5-pyridine dicarboxylates. 114
DNA minor groove alkylating agents structurally related to distamycin A 112
New potent and selective human adenosine A3 receptor antagonists. 112
A new synthetic approach to indazole synthesis 109
8-(2-Furyl)adenine derivatives as A₂A adenosine receptor ligands 107
Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs) 107
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A1 adenosine receptor antagonists 106
Oligonucleotides and oligonucleotide conjugates: A new approach for cancer treatment 105
null 104
Design, synthesis and biological activity of a pyrrolo[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid 104
Selective binding to human genomic sequences of two synthetic analogues structurally related to U-71184 and adozelesin 104
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 104
Resolution of a CPzI precursor, synthesis and biological evaluation of (+) and (-)-N-Boc-CPzI: A further validation of the relationship between chemical solvolytic stability and cytotoxicity 103
DNA minor-groove binders: results and design of new antitumor agents 102
Carbon nanotube substrates boost neuronal electrical signaling 102
Nitrile oxide [3 + 2] cycloaddition: application to the synthesis of 6-substituted 3(2H)-pyridazinones and 6-substituted 4,5-dihydro-4-hydroxy-3(2H)-pyridazinones 101
Structure-activity relationship of novel tallimustine derivatives: Synthesis and antitumor activity 101
Synthesis and preliminary biological evaluation of [H-3]-MRE 3008-F20: the first high affinity radioligand antagonist for the human A(3) adenosine receptors 99
An efficient procedure for the synthesis of 5H-6-substituted-pyrazolo[1,5-d]-1,2,4-triazine-4,7-diones 99
A2A-adenosine receptor reserve for coronary vasodilation 98
Facile and versatile route to the synthesis of fused 2-pyridones: Useful intermediates for polycyclic sytems 97
Synthesis and Antitumor Activity of a New Class of Pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone Analogs of Pyrrolo[1,4][2,1-c]benzodiazepines 97
Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors 96
Ethyl-(R,S)-5-acetyl-4,5-dihydro-3-isoxazole acetate 95
Linear and nonlinear 3D-QSAR approaches in tandem with ligand-based homology modeling as a computational strategy to depict the pyrazolo-triazolo- pyrimidine antagonists binding site of the human adenosine A2A receptor 95
Ethyl (R,S)-5-acetyl-4,5-dihydro-3-isoxazoleacetate 95
Solid lipid microparticles for the stability enhancement of a dopamine prodrug 94
Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c] [1,4]benzodiazepines 94
New potent and selective human adenosine A3 receptor antagonists 93
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: A complete structure-activity profile 92
The Significance of 2-Furyl Ring Substitution with a 2-(para-substituted) Aryl Group in a New Series of Pyrazolo-triazolo-pyrimidines as Potent and Highly Selective hA3 Adenosine Receptors Antagonists: New Insights into Structure-Affinity Relationship and Receptor-Antagonist Recognition 92
Chemical synthesis of [13C]daidzein. 91
Synthesis and properties of substituted CBI analogs of CC-1065 and the duocarmycins incorporating the 7-methoxy-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (MCBI) alkylation subunit: Magnitude of electronic effects on the functional reactivity 91
CC-1065 and the duocarmycins: recent developments 90
null 90
Structure Activity Relationship of 4-Amino-2-thiopyrimidine Derivatives as Platelet Aggregation Inhibitors 90
Synthesis and Biological Evaluation of a New Series of 1,2,4-Triazolo[1,5-a]-1,3,5-triazines as Human A(2A) Adenosine Receptor Antagonists with Improved Water Solubility 90
Exploring Potency and Selectivity Receptor Antagonist Profiles Using a Multilabel Classification Approach: The Human Adenosine Receptors as a Key Study 88
Synthesis of pyridazine derivatives through the unexpected intermediate 5-amino-4-cyano-2,3-dihydro-furan-2,3-disulfonic acid disodium salt 88
null 87
Synthesis, biological studies and molecular modeling investigation of 1,3-dimethyl-2,4-dioxo-6-methyl-8-(substituted) 1,2,3,4-tetrahydro [1,2,4]-triazolo [3,4-f]-purines as potential adenosine receptor antagonists 87
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes 87
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 86
Cosmetic preservation and structure-activity relationships of 4-diazo-pyrazole-5-carboxamides 86
Demystifying the three dimensional structure of G protein-coupled receptors (GPCRs) with the aid of molecular modeling 86
Carbon Nanotubes Carrying Cell-Adhesion Peptides do not Interfere with Neuronal Functionality 83
Antiproliferative effects of novel synthetic nucleobase analogues on U937 Histiocytic lymphoma cell line 83
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 82
Recent developments in the field of adenosine receptor ligands 80
Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process 80
1H-pyrazolo[4,3-d]pyrimidine-7(6H)-one and 5H-pyrazolo[4,3-d] 1,2,3-triazin-4(3H)-one derivatives. Synthesis and in vitro biological activity at adenosine A1 and A2a receptors 80
A(3) adenosine receptor ligands: History and perspectives 79
Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors 78
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 78
null 77
Substituted 6-amino-thiouracils as new P2Y(12) receptor antagonists 76
[3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 76
Pyrazolo [4,3-E]1,2,4-triazolo[1,5-c]pyrimidine derivates a new class of potent and selective human A3 adenosine receptor antagonists. 75
Novel N-6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A(3) adenosine receptors 74
Schematic overview of oligosaccharides, with survey on their major physiological effects and a focus on milk ones 74
Synthesis and cardiodepressant activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(pentatomic-heteroaryl)-3,5-pyridinedicarboxylates. 2 73
7-sobstituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonist: importance of modifications at the side chain on the activity and solubility. 73
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 73
A(1) and A(3) adenosine receptor agonists: an overview 72
Unusual Ring-Opening Reaction of 6,7-Dihydrothieno[3,2-d]pyrimidine- 2,4-dione Derivatives Leading to 5-(Alkylthio)-6-vinyluracils 71
Synthesis and Biological Activity of a New Series of N6-Arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-Carboxamido Derivatives of Adenosine-5'-N-ethyluronamide as A1 and A3 Adenosine Receptor Agonists 71
[3H]MRE3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 70
Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists 70
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]-pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists 69
Pyridazine nucleus: a pharmacophoric moiety for bio-active compounds 68
A2Aadenosine receptor antagonists as therapeutic candidates: Are they still an interesting challenge? 68
Rationale design of new human adenosione A3 receptor antagonists through a CoMFA model. 67
Synthesis, antibacterial activity and structure-activity relationships of N-substituted 4-diazopyrazole-5-carboxamides. 2 66
Heterocyclic analogs of DNA minor groove alkylating agents 66
Synthesis, biological and modeling studies of new water soluble hA3 adenosine receptor antagonists. 66
Synthesis and molecular investigation of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivates as human A3 adenosine receptor antagonists. 66
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives: Potent and selective A2A adenosine antagonists 66
Synthesis, binding and thermodynamic studies of new highly selective A2A adenosine receptor antagonists 65
Synthesis and molecular investigation of new pyrazolo[4,3-e]1,2,4,-triazolo[1,5-c]pyrimidine derivates as human A3 adenosine receptor antagonists. 64
Comparative molecular field analysis (CoMFA) of a series of selective adenosine receptor A(2A) antagonists 63
Synthesis, cytotoxicity and antitumor activity of some new simplified pyrazole analogs of the antitumor agent CC-1065. Effect of an hydrophobic group on antitumor activity 61
Triazolo-triazine as new adenosine receptor antagonists. 60
Binding affinity of adenosine receptor agonists and antagonists at human A3 adenosine receptors 60
Conjugation of Dopamine and an A2A Adenosine Receptor Antagonist: a possible approach for the treatment of Parkinson’s Disease. 60
Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist 59
Synthesis, antiviral and antiproliferative activity of a new class of 5-(alkyl or arylthio)-6-vinyl uracils 59
Current developments of A(2a) adenosine receptor antagonists 58
Synthesis, biological properties and molecular modelling investigation of the first potent, selective and water soluble human A3 adenosine receptor antagonist. 58
Second generation of A2A adenosine receptor antagonist: synthesis and biological evaluation 58
Totale 9.235
Categoria #
all - tutte 44.749
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 224
Totale 44.973


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.280 457 72 58 329 138 260 190 234 165 265 75 37
2020/20211.641 144 145 112 183 50 167 32 199 36 188 232 153
2021/20221.361 39 138 78 135 85 51 42 83 38 98 153 421
2022/20231.317 158 63 26 171 220 223 31 118 173 8 73 53
2023/2024810 70 92 34 21 71 60 20 260 12 12 10 148
2024/202538 38 0 0 0 0 0 0 0 0 0 0 0
Totale 11.244