DI VIRGILIO, Francesco
 Distribuzione geografica
Continente #
NA - Nord America 34.108
EU - Europa 19.159
AS - Asia 18.699
SA - Sud America 2.974
AF - Africa 393
OC - Oceania 65
Continente sconosciuto - Info sul continente non disponibili 22
Totale 75.420
Nazione #
US - Stati Uniti d'America 33.453
FI - Finlandia 8.424
SG - Singapore 7.159
CN - Cina 4.617
DE - Germania 2.985
BR - Brasile 2.295
VN - Vietnam 2.128
IT - Italia 1.949
UA - Ucraina 1.671
HK - Hong Kong 1.581
TR - Turchia 1.116
GB - Regno Unito 1.054
RU - Federazione Russa 786
FR - Francia 671
JP - Giappone 508
SE - Svezia 416
PL - Polonia 378
IN - India 353
MX - Messico 308
ID - Indonesia 265
CA - Canada 253
AR - Argentina 223
BD - Bangladesh 199
NL - Olanda 166
IQ - Iraq 131
ZA - Sudafrica 127
EC - Ecuador 122
BE - Belgio 115
ES - Italia 101
PK - Pakistan 89
CO - Colombia 85
VE - Venezuela 77
LT - Lituania 67
PH - Filippine 63
SA - Arabia Saudita 62
MA - Marocco 60
IE - Irlanda 58
UZ - Uzbekistan 58
AU - Australia 55
MY - Malesia 47
AT - Austria 44
CL - Cile 41
KE - Kenya 41
PE - Perù 41
PY - Paraguay 41
TN - Tunisia 39
CZ - Repubblica Ceca 38
CH - Svizzera 34
RO - Romania 31
AE - Emirati Arabi Uniti 29
DK - Danimarca 29
TH - Thailandia 27
IL - Israele 26
IR - Iran 26
EG - Egitto 25
KR - Corea 25
BO - Bolivia 24
NP - Nepal 24
CR - Costa Rica 20
AZ - Azerbaigian 19
DZ - Algeria 18
JO - Giordania 18
OM - Oman 17
DO - Repubblica Dominicana 15
ET - Etiopia 15
GR - Grecia 14
KG - Kirghizistan 14
LB - Libano 14
LV - Lettonia 14
UY - Uruguay 14
JM - Giamaica 13
MD - Moldavia 13
SK - Slovacchia (Repubblica Slovacca) 13
TW - Taiwan 13
AL - Albania 12
HR - Croazia 12
PS - Palestinian Territory 12
AO - Angola 11
BG - Bulgaria 11
EU - Europa 11
KZ - Kazakistan 11
HN - Honduras 10
PA - Panama 10
SN - Senegal 10
RS - Serbia 9
HU - Ungheria 8
BH - Bahrain 7
GY - Guiana 7
PT - Portogallo 7
AM - Armenia 6
BB - Barbados 6
NG - Nigeria 6
NZ - Nuova Zelanda 6
XK - ???statistics.table.value.countryCode.XK??? 6
A2 - ???statistics.table.value.countryCode.A2??? 5
BA - Bosnia-Erzegovina 5
CI - Costa d'Avorio 5
EE - Estonia 5
GE - Georgia 5
LU - Lussemburgo 5
Totale 75.312
Città #
Helsinki 7.919
Singapore 4.453
Ashburn 3.710
Fairfield 3.222
Woodbridge 3.031
Houston 2.140
Jacksonville 1.830
Chandler 1.735
San Jose 1.730
Ann Arbor 1.603
Hong Kong 1.543
Santa Clara 1.480
Beijing 1.342
Wilmington 1.204
Seattle 1.177
Cambridge 941
Ho Chi Minh City 709
Munich 696
Izmir 690
Ferrara 568
Nanjing 533
Hanoi 523
Los Angeles 493
Tokyo 474
Dallas 459
Princeton 441
Lauterbourg 378
New York 362
Warsaw 332
Boardman 307
San Diego 292
São Paulo 241
Shanghai 219
Addison 209
Mexico City 195
Milan 191
Council Bluffs 180
Jakarta 167
Buffalo 156
Nanchang 151
Shenyang 146
London 137
Chicago 136
Dearborn 134
Tianjin 128
Orem 122
Bremen 115
Turku 114
Hefei 113
Da Nang 107
Hebei 107
Frankfurt am Main 106
Jiaxing 96
Brussels 94
Brooklyn 92
Moscow 92
Changsha 86
Manchester 86
Redwood City 86
Chennai 81
Montreal 80
The Dalles 75
Haiphong 74
Atlanta 71
Denver 71
Nuremberg 69
Rio de Janeiro 69
Toronto 69
Mountain View 68
Rome 68
Norwalk 67
Amsterdam 66
Johannesburg 65
Boston 63
Guangzhou 60
Zhengzhou 59
San Francisco 58
Stockholm 58
Falls Church 57
Baghdad 56
Dong Ket 56
Jinan 56
Falkenstein 54
Tashkent 52
Bologna 51
Brasília 51
Poplar 49
San Mateo 48
Columbus 45
Quito 45
Hải Dương 43
Kunming 43
Mumbai 42
Ningbo 41
Phoenix 39
Curitiba 38
Belo Horizonte 37
Dublin 37
Hangzhou 37
Dhaka 36
Totale 52.427
Nome #
A new luciferase target to the extracellular surface of the plasma membrane reveals a new pathway for ATP release in live intact cells. 2.228
A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion 2.156
A new method for measuring local ATP release at the extracellular surface of live intact cells 2.073
A role for calcium in Bcl-2 action? 2.030
P2X7 receptor involvement in the pathogenesis of Hidradenitis Suppurativa 465
A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes. 407
Characterization of P2X7 isoform B sheds light on the role of pore versus channel activity in P2X7 mediated life and death. 371
Increased level of extracellular ATP at tumor sites: In vivo imaging with plasma membrane luciferase 355
I recettori purinergici P2 e le ectonucleotidasi: nuovi bersagli per lo sviluppo di farmaci anti-tumorali/P2 purinergic receptors and ectonucleotidases: novel targets for anti-cancer drugs (FIRB Accordi di programma n. RBAP11FXBC) 354
Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7 318
P2X7 targeting inhibits growth of human mesothelioma 301
Il recettore purinergico P2X7 come modulatore della fisiologia mitocondriale e del processo apoptotico 288
IL PROCESSO INFIAMMATORIO 285
1513A>C polymorphism in the P2X7 receptor gene in patients with papillary thyroid cancer: Correlation with histological variants and clinical parameters 278
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 278
p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner 272
Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death 270
Extracellular ATP and P2 purinergic signalling in the tumour microenvironment 261
Involvement of the purinergic P2X7 receptor in the formation of multinucleated giant cells 260
Amyloid beta-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine 257
Silencing of P2X7 receptor reduces B16 melanoma growth both in vitro and in vivo 256
ATP release from chemotherapy-treated dying leukemia cells Elicits an immune suppressive effect by increasing regulatory T cells and Tolerogenic dendritic cells 253
ATP-mediated cytotoxicity in microglial cells 251
Anti-Tumor Activity of a miR-199-dependent Oncolytic Adenovirus 251
The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein 249
Expression of P2X7 receptor increases in vivo tumor growth 247
Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes 243
Role of P2X7 receptor in host response to melanoma 240
An ATP-activated channel is involved in mitogenic stimulation of human T lymphocytes 238
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 235
P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration 231
5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes 227
Purinergic signaling in the immune system 226
Plasma P2X7 receptor correlation with plasma C-reactive protein in infectious diseases 226
Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis 225
The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination 224
Activation of human eosinophils via P2 receptors: novel findings and future perspectives 223
ATP receptors and giant cell formation 222
The P2X7 receptor : from ion channel to oncogene 222
P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia 221
Insight on P2X7 receptor role as oncogene 220
Increased sensitivity to extracellular ATP of fibroblasts from patients affected by systemic sclerosis 218
A defect in glycogen synthesis characterizes insulin resistance in hypertensive patients with type 2 diabetes 214
The antibiotic polymyxin B modulates P2X7 receptor function 214
Blockade of P2X7 receptor inhibits formation of multinucleated giant cells. 213
Extracellular nucleotides and nucleosides as signalling molecules 213
ATP secreted by endothelial cells blocks CX 3CL1-elicited natural killer cell chemotaxis and cytotoxicity via P2Y 11 receptor activation 212
Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice 212
Intracellular signalling in Te85 osteosarcoma cells expressing P2X7R isoforms A and B 212
Acute myeloid leukaemia:analysis of the expression of P2X7a and P2X7B isoforms 212
Non-nucleotide agonists triggering P2X7 receptor activation and pore formation 212
Human primary keratinocytes express functional P2 receptors whose expression is modulated by inflammatory cytokines. 211
Purinoceptor function in the immune system 211
Extracellular ATP exerts opposite effects on activated and regulatory CD4+ T cells via purinergic P2 receptor activation 211
The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration 210
Antibiotics and natural peptides as modulators of P2X7 functions 210
Stimulation of Purinergic Receptors Modulates Chemokine Expression in Human Keratinocytes 210
P2X7A and B as novel biomarkers of acute myeloid leukemia response to chemotherapy and innovative therapeutic targets for the disease 210
Dysfunctional inflammasome in Schnitzler's syndrome 208
The P2X7 Receptor in Infection and Inflammation 207
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 206
Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma 206
Inhibitory effect of P2X7 receptor antagonists on in vivo tumor growth 205
The P2X7 receptor: A main player in inflammation 205
Altered expression and function of P2X7 receptorin patients affected by Systemic Lupus Erythematosus (SLE) 205
The human cathelicidin LL-37 modulates the activities of the P2X 7 receptor in a structure-dependent manner 204
The antibiotic polymyxin B modulates P2X7 receptor function 203
The P2X7 receptor is a key modulator of aerobic glycolysis. 203
La stimolazione del recettore P2X7 causa il rilascio di microvescicole contenenti IL-1 beta da parte di cellule dendritiche umane 202
Idiopatic inflammatory myopathies: serological and clinical correlations. Analysis of a monocentric series 202
Human keratinocytes express functional P2 receptors whose expression is modulated by inflammatory cytokines. 202
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 201
Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation 200
P2X7 contemporarily impacts melanoma growth and anti-melanoma defense 200
P2X7 receptor as key modulator of PI3K/HIF1a/GSK3b metabolic pathway in neuroblastoma 199
Tyrosine phosphorylation of HSP90 within the P2X7 receptor complex negatively regulates P2X7 receptors 199
Increased sensitivity of DMD lymphoblastoid cell to low doses of X irradiation 198
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance 198
Extracellular purines, purinergic receptors and tumor growth 197
Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance 197
The P2X7 receptor: a key player in IL-1 processing and release 196
Defective P2Y purinergic receptor function induces impaired glucose transport in type 2 diabetes. 196
The P2X7 Receptor Is Shed Into Circulation: Correlation With C-Reactive Protein Levels 196
Detection of extracellular ATP in the tumor microenvironment, using the pmeLUC biosensor 196
Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells 195
Altered IL-1ß secretion in a patient affected by Schnitzler's syndrome 194
Alerting and tuning the immune response by extracellular nucleotides 194
P2 receptors in cancer progression and metastatic spreading 194
A ROLE FOR P2X7 RECEPTORS IN MICROGLIA PROLIFERATION 193
“Hemophagocytic Lymphohistiocytosis after EBV reactivation and ibrutinib treatment in relapsed/refractory Chronic Lymphocytic Leukemia” 193
Role of P2X7 polymorphisms in idiopathic infertility and HHV-6A infection 191
Purinergic P2Y(2) Receptors Promote Neutrophil Infiltration and Hepatocyte Death in Mice With Acute Liver Injury 190
Calcium and apoptosis: facts and hypotheses 190
Calcium and inositolphosphates in the activation of T cell-mediated cytotoxicity 189
CYTOLYTIC P2X PURINOCEPTORS 188
ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment. 187
Defective P2Y purinergic receptor function: A possible novel mechanism for impaired glucose transport 187
Apoptosis is dependent on intracellular zinc and independent of intracellular calcium in lymphocytes 187
Increased reticular calcium content is related to NFATc1 activation and apoptosis resistance due to P2x7R expression 187
The P2X7 receptor: a key determinant of cellular metabolic energetics in cancer progression - AIRC IG 18581 187
Totale 30.319
Categoria #
all - tutte 301.763
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 7.217
Totale 308.980


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.721 0 0 0 0 0 0 0 0 0 659 703 359
2021/20224.501 123 468 260 157 278 213 237 250 197 356 434 1.528
2022/20234.150 486 173 139 487 685 598 123 447 540 53 280 139
2023/20242.128 235 314 91 62 189 262 91 145 47 49 93 550
2024/20259.632 266 276 718 359 1.146 1.019 420 624 1.616 1.015 1.147 1.026
2025/202631.300 2.528 1.032 2.157 3.312 3.794 1.534 3.131 1.588 9.938 2.286 0 0
Totale 76.130