Distribuzione geografica
Continente #
NA - Nord America 12.991
EU - Europa 3.583
AS - Asia 1.525
SA - Sud America 24
OC - Oceania 9
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 18.138
Nazione #
US - Stati Uniti d'America 12.963
CN - Cina 994
IT - Italia 983
UA - Ucraina 849
DE - Germania 444
TR - Turchia 438
GB - Regno Unito 365
PL - Polonia 286
SE - Svezia 190
FI - Finlandia 176
AT - Austria 107
BE - Belgio 60
FR - Francia 45
CA - Canada 24
IN - India 19
NL - Olanda 18
VN - Vietnam 18
RU - Federazione Russa 13
BR - Brasile 10
IR - Iran 10
RO - Romania 10
CH - Svizzera 9
PK - Pakistan 9
AU - Australia 8
CL - Cile 8
KR - Corea 8
ES - Italia 7
GR - Grecia 6
JP - Giappone 5
ID - Indonesia 4
MX - Messico 4
BG - Bulgaria 3
EG - Egitto 3
IL - Israele 3
IQ - Iraq 3
SG - Singapore 3
AR - Argentina 2
CO - Colombia 2
HK - Hong Kong 2
HU - Ungheria 2
IE - Irlanda 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
BD - Bangladesh 1
DK - Danimarca 1
EE - Estonia 1
EU - Europa 1
KG - Kirghizistan 1
LU - Lussemburgo 1
MA - Marocco 1
MD - Moldavia 1
MN - Mongolia 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PE - Perù 1
PT - Portogallo 1
SA - Arabia Saudita 1
UY - Uruguay 1
ZA - Sudafrica 1
Totale 18.138
Città #
Fairfield 2.063
Woodbridge 1.742
Houston 1.181
Jacksonville 944
Chandler 850
Seattle 813
Ashburn 794
Cambridge 708
Ann Arbor 702
Wilmington 681
Izmir 343
Warsaw 285
Nanjing 278
Princeton 237
Beijing 206
Ferrara 192
San Diego 182
Milan 146
Boardman 137
Nanchang 82
Vienna 78
Shenyang 77
Addison 64
Brussels 58
Bremen 52
Tianjin 52
Hebei 50
Jiaxing 45
Falls Church 42
Redwood City 42
London 40
Norwalk 40
Changsha 35
Mountain View 34
San Mateo 33
Jinan 32
Auburn Hills 27
Des Moines 27
Orange 27
Rome 25
Guangzhou 21
Kunming 19
Bologna 18
Zhengzhou 17
Dong Ket 16
Ferrara di Monte Baldo 16
Monmouth Junction 16
Indiana 14
Verona 14
Washington 14
Napoli 13
Philadelphia 13
Taizhou 13
Dearborn 12
Munich 12
Tappahannock 12
Los Angeles 11
Ningbo 11
Augusta 10
Lanzhou 10
New York 10
Catanzaro 8
Hangzhou 8
Helsinki 8
Leawood 8
Shanghai 8
Guarda Veneta 7
Islamabad 7
Rende 7
Toronto 7
Ardabil 6
Casalecchio Di Reno 6
Chicago 6
San Francisco 6
Atella 5
Como 5
Dallas 5
Gurgaon 5
Islington 5
Mcallen 5
Montréal 5
Padova 5
Paris 5
Redmond 5
Torino 5
Vicenza 5
Aviano 4
Changchun 4
Chiswick 4
Donostia-san Sebastián 4
Hanover 4
Itajaí 4
Manchester 4
Yellow Springs 4
Amsterdam 3
Botosani 3
Campobasso 3
Edinburgh 3
Erlangen 3
Hefei 3
Totale 13.940
Nome #
Trasmissione catecolaminergica 400
Sistemi di trasmissione - trasmissione catecolaminergica. 196
Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment 184
Preclinical studies with modafinil. Evidence for vigilance enhancement and neuroprotection. 179
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence 176
GET73 prevents ethanol-induced neurotoxicity in primary cultures of rat hippocampal neurons 148
Neurotensin: A role in substance use disorder? 145
Differential Effects of Palmitoylethanolamide against Amyloid-β Induced Toxicity in Cortical Neuronal and Astrocytic Primary Cultures from Wild-Type and 3xTg-AD Mice 143
Indomethacin co-crystals and their parent mixtures: does the intestinal barrier recognize them differently? 141
Neurotensin enhances endogenous extracellular glutamate levels in primary cultures of rat cortical neurons: involvement of neurotensin receptor in NMDA induced excitotoxicity 140
Geraniol pharmacokinetics, bioavailability and its multiple effects on the liver antioxidant and xenobiotic-metabolizing enzymes 140
Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson's disease and schizophrenia. 139
Acute exposure to methylmercury at two developmental windows: Focus on neurobehavioral and neurochemical effects in rat offspring 138
Psychostimulant effect of the synthetic cannabinoid JWH-018 and AKB48. Behavioural, neurochemical and Dopamine transporter scan imaging studies in mice 138
Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia 131
Efficient synthesis and biological evaluation of two modafinil analogues 123
Nasal chitosan microparticles target a zidovudine prodrug to brain HIV sanctuaries 122
Effect of acute and subchronic nicotine treatment on cortical efflux of [3H]-D-aspartate and endogenous GABA in freely moving guinea-pigs. 121
Behavioral and neurochemical studies on brain aging in galanin overexpressing mice 121
Functional role of striatal A2A, D2, and mGlu5 receptor interactions in regulating striatopallidal GABA neuronal transmission 120
A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approach 119
Brain targeting of resveratrol by nasal administration of chitosan-coated lipid microparticles 119
Adenosine a2a-d2 receptor-receptor interactions in putative heteromers in the regulation of the striato-pallidal gaba pathway: Possible relevance for parkinson’s disease and its treatment 118
Modafinil: an antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers 117
Solid microparticles based on chitosan or methyl-beta-cyclodextrin: A first formulative approach to increase the nose-to-brain transport of deferoxamine mesylate 115
Ascorbic and 6-Br-ascorbic acid conjugates as a tool to increase the therapeutic effects of potentially central active drugs 114
Amplification of cortical serotonin release: a further neurochemical action of the vigilance-promoting drug modafinil. 114
Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity. 113
The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat: prevention by local GABAA receptor blockade 113
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices 113
Transporter-mediated effects of diclofenamic acid and its ascorbyl pro-drug in the in vivo neurotropic activity of ascorbyl nipecotic acid conjugate 112
GPCR heteromers and their allosteric receptor-receptor interactions 111
A stereological study on the neuroprotective actions of acute modafinil treatment on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigral lesions of the male black mouse 110
A new multi-charged C60 derivative: synthesis and biological properties 110
Alterations of prefrontal cortex GABAergic transmission in the complex psychotic-like phenotype induced by adolescent delta-9-tetrahydrocannabinol exposure in rats. 110
Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers. 110
Biological markers in cerebrospinal fluid for axonal impairment in multiple sclerosis: acetylcholinesterase activity cannot be considered a useful biomarker 110
Receptor-receptor interactions as studied with microdialysis. Focus on NTR/D2 interactions in the basal ganglia 110
6-Hydroxy-dopamine treatment counteracts the reduction of cortical GABA release produced by the vigilance promoting drug modafinil in the awake freely moving guinea-pig 108
Carnitine Conjugate of Nipecotic acid: A new example of dual prodrug 106
Understanding the balance and integration of volume and synaptic transmission. Relevance for psychiatry 106
5-Hydroxytryptamine-mediated effects of nicotine on endogenous GABA efflux from guinea-pig cortical slices. 106
Neurotensin receptor involvement in the rise of extracellular glutamate levels and apoptotic nerve cell death in primary cortical cultures after oxygen and glucose deprivation. 105
Effect of (-)nicotine on GABA efflux from guinea pig cerebral cortex slices. 105
Exploring the use of spray congealing to produce solid dispersions with enhanced indomethacin bioavailability: In vitro characterization and in vivo study 105
Neurotensin and cholecystokinin octapeptide control synergistically dopamine release and dopamine D2 receptor affinity in rat neostriatum. 104
null 104
Neurochemical changes in the striatum of dyskinetic rats after administration of the cannabinoid agonist WIN55,212-2. 104
Neurotensin peptides antagonistically regulate postsynaptic dopamine D2 receptors in rat nucleus accumbens: a receptor binding and microdialysis study. 104
CHF5074 and LY450139 sub-acute treatments differently affect cortical extracellular glutamate levels in pre-plaque Tg2576 mice. 104
Striatal adenosine-cannabinoid receptor interactions in rats over-expressing adenosine A2A receptors. 104
Long-lasting alterations of hippocampal GABAergic neurotransmission in adult rats following perinatal Δ9-THC exposure 104
Differential effects of acute and short-term lithium administration on dialysate glutamate and GABA levels in the frontal cortex of the conscious rat 103
null 103
Nigral neurotensin receptor regulation of nigral glutamate and nigro-ventral thalamic GABA transmission. A dual probe microdialysis study in intact conscious rat brain. 103
The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism. 103
Short- and long-term consequences of prenatal exposure to the cannabinoid agonist WIN55,212-2 on rat glutamate transmission and cognitive functions. 103
Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 and carbon monoxide reduces extracellular glutamate levels in primary rat cerebral cortex cell cultures 102
The antinarcoleptic drug modafinil increases glutamate release in thalamic areas and hippocampus. 102
Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson's Disease. 102
On the role of the extracellular space on the holistic behavior of the brain 102
Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease 102
Cocaine modulates allosteric D2-σ1 receptor-receptor interactions on dopamine and glutamate nerve terminals from rat striatum 102
null 101
Exploring the Use of Spray Congealing to Produce Solid Dispersions with Enhanced Indomethacin Bioavailability 101
Modafinil enhances the increase of extracellular serotonin levels induced by the antidepressant drugs fluoxetine and imipramine: a dual probe microdialysis study in awake rat. 100
Prenatal Exposure to the CB1 Receptor Agonist WIN 55,212-2 Causes Learning Disruption Associated with Impaired Cortical NMDA Receptor Function and Emotional Reactivity Changes in Rat Offspring 100
Neurotensin as Modulator of Basal Ganglia- Thalamocortical Motor Circuit – Emerging Evidence for Neurotensin NTS1 Receptor as a Potential Target in Parkinson's Disease 100
Neurotensin receptors as modulators of glutamatergic transmission. 100
Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 increases glutamate uptake through overexpression of GLT1 and EAAC1 glutamate transporter subtypes in rat frontal cerebral cortex. 99
Perinatal exposure to delta-9-tetrahydrocannabinol causes enduring cognitive deficits associated with alteration of cortical gene expression and neurotransmission in rats. 99
Long-term effects on cortical glutamate release induced by prenatal exposure to the cannabinoid receptor agonist (R)-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinyl-methyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone: an in vivo microdialysis study in the awake rat. 99
Emerging Evidence for Neurotensin Receptor 1 Antagonists as Novel Pharmaceutics in Neurodegenerative Disorders. 99
Neurotensin regulates cortical glutamate transmission by modulating N-methyl-D-aspartate receptor functional activity: an in vivo microdialysis study. 99
Facilitation of GABA release by neurotensin is associated with a reduction of dopamine release in rat nucleus accumbens. 99
Changes in gamma-aminobutyric acid release induced by topical administration of drugs affecting its metabolism and receptors: studies in freely moving guinea pigs with epidural cups. 99
Integrated signaling in heterodimers and receptor mosaics of different types of GPCRs of the forebrain: relevance for schizophrenia. 98
Neurotensin increases endogenous glutamate release in rat cortical slices. 98
Relevance of dopamine D2/neurotensin NTS1 and NMDA/neurotensin NTS1 receptor interaction in psychiatric and neurodegenerative disorders 98
Modafinil does not affect serotonin efflux from rat frontal cortex synaptosomes: comparison with known serotonergic drugs. 98
The Pharmacokinetics and Efficacy of Ropivacaine Continuous Wound Instillation after Spine Fusion Surgery 98
Oxcarbazepine free or loaded PLGA nanoparticles as effective intranasal approach to control epileptic seizures in rodents 98
Evidence for a differential cholecystokinin-B and -A receptor regulation of GABA release in the rat nucleus accumbens mediated via dopaminergic and cholinergic mechanisms. 97
Uptake in the Central Nervous System of Geraniol Oil Encapsulated in Chitosan Oleate Following Nasal and Oral Administration 97
A novel mechanism of cocaine to enhance dopamine D 2-like receptor mediated neurochemical and behavioral effects. An in vivo and in vitro study 97
Excitatory amino acids (EAAs) stimulate phosphatidylinositol turnover in adult rat striatal slices: interaction between NMDA and EAA metabotropic receptors. 96
Inhibitory cholinergic control of endogenous GABA release from electrically stimulated cortical slices and K(+)-depolarized synaptosomes 96
Modafinil prevents glutamate cytotoxicity in cultured cortical neurons. 96
Cannabinoid CB1 and cholecystokinin CCK2 receptors modulate, in an opposing way, electrically evoked [3H]GABA efflux from rat cerebral cortex cell cultures: possible relevance for cortical GABA transmission and anxiety. 96
The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT3 receptor 95
Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks. 95
Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes. 95
null 95
Enhanced striatal glutamate release after the administration of rimonabant to 6-hydroxydopamine-lesioned rats. 94
Pharmacokinetics and efficacy of ropivacaine continuous wound instillation after joint replacement surgery 94
Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease. 94
CHF5074 restores visual memory ability and pre-synaptic cortical acetylcholine release in pre-plaque Tg2576 mice 94
Ultramicronized palmitoylethanolamide rescues learning and memory impairments in a triple transgenic mouse model of Alzheimer's disease by exerting anti-inflammatory and neuroprotective effects 94
Astrocytic Mechanisms Involving Kynurenic Acid Control Δ9-Tetrahydrocannabinol-Induced Increases in Glutamate Release in Brain Reward-Processing Areas 94
Role of c-Fos protein on glutamate toxicity in primary neural hippocampal cells. 93
Totale 11.374
Categoria #
all - tutte 48.461
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 3.420
Totale 51.881

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20192.966 0 0 40 101 27 29 274 34 204 502 651 1.104
2019/20204.591 685 196 171 689 325 506 385 473 378 398 218 167
2020/20213.222 258 261 212 306 145 253 254 364 136 504 347 182
2021/20222.246 89 267 270 91 80 98 137 120 78 168 214 634
2022/20232.229 243 90 63 239 370 306 162 233 259 30 141 93
2023/2024356 134 168 54 0 0 0 0 0 0 0 0 0
Totale 18.490