SECCHIERO, Paola
 Distribuzione geografica
Continente #
NA - Nord America 18.879
EU - Europa 4.627
AS - Asia 3.324
SA - Sud America 26
OC - Oceania 11
AF - Africa 10
Continente sconosciuto - Info sul continente non disponibili 4
Totale 26.881
Nazione #
US - Stati Uniti d'America 18.835
CN - Cina 1.581
IT - Italia 1.095
UA - Ucraina 1.004
SG - Singapore 801
DE - Germania 722
TR - Turchia 630
PL - Polonia 558
GB - Regno Unito 501
FI - Finlandia 239
SE - Svezia 230
ID - Indonesia 145
FR - Francia 63
RU - Federazione Russa 63
VN - Vietnam 59
BE - Belgio 47
CA - Canada 43
HK - Hong Kong 42
CZ - Repubblica Ceca 31
BR - Brasile 22
NL - Olanda 21
LT - Lituania 16
IR - Iran 15
IN - India 14
AU - Australia 11
KR - Corea 11
IE - Irlanda 8
ES - Italia 7
JP - Giappone 7
EG - Egitto 5
RO - Romania 5
TW - Taiwan 5
BG - Bulgaria 4
TN - Tunisia 4
IL - Israele 3
MY - Malesia 3
BD - Bangladesh 2
CL - Cile 2
EU - Europa 2
GE - Georgia 2
GR - Grecia 2
MD - Moldavia 2
A1 - Anonimo 1
A2 - ???statistics.table.value.countryCode.A2??? 1
AT - Austria 1
AZ - Azerbaigian 1
CH - Svizzera 1
CO - Colombia 1
CY - Cipro 1
DK - Danimarca 1
IQ - Iraq 1
KE - Kenya 1
LI - Liechtenstein 1
LU - Lussemburgo 1
MC - Monaco 1
MK - Macedonia 1
MX - Messico 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
VE - Venezuela 1
Totale 26.881
Città #
Fairfield 2.805
Woodbridge 2.506
Houston 1.605
Ashburn 1.333
Jacksonville 1.164
Seattle 1.119
Chandler 1.099
Ann Arbor 1.062
Wilmington 988
Cambridge 950
Singapore 644
Santa Clara 581
Warsaw 556
Ferrara 489
Izmir 369
Nanjing 333
Beijing 282
Princeton 279
Boardman 229
San Diego 213
Jakarta 144
New York 137
Shanghai 130
Milan 125
Nanchang 106
Shenyang 104
Dearborn 98
Los Angeles 87
Falls Church 70
Tianjin 70
Changsha 63
London 60
Hebei 59
Dong Ket 56
Jiaxing 54
Mountain View 54
Bremen 47
Brussels 47
Bologna 42
San Mateo 40
Kunming 39
Norwalk 39
Zhengzhou 38
Redwood City 37
Hong Kong 36
Jinan 36
Auburn Hills 35
Munich 35
Tappahannock 32
Brno 27
Addison 26
Orange 23
Toronto 22
Guangzhou 20
Washington 20
Ferrara di Monte Baldo 18
Helsinki 18
Ningbo 18
Verona 18
Frankfurt am Main 17
Leawood 17
Ottawa 17
Padova 17
Des Moines 16
Philadelphia 16
Sanayi 16
Scottsdale 16
Indiana 13
Ardabil 12
Augusta 12
Changchun 12
Redmond 12
Haikou 11
Hounslow 11
Taizhou 11
Chicago 10
Rome 10
Hefei 9
Kilburn 9
Imola 8
Hangzhou 7
Lanzhou 7
Lappeenranta 7
Palermo 7
San Francisco 7
Dronten 6
Matera 6
Monmouth Junction 6
Prescot 6
Acton 5
Nam-gu 5
Parma 5
Trieste 5
Ariano nel Polesine 4
Bari 4
Cogorno 4
Forlì 4
Lauria 4
Sofia 4
Taiyuan 4
Totale 21.115
Nome #
Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model 187
Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model 177
The anti-leukemic activity of sodium dichloroacetate in p53(mutated/null) cells is mediated by a p53-independent ILF3/p21 pathway 175
MDM2/X inhibitors under clinical evaluation: Perspectives for the management of hematological malignancies and pediatric cancer 173
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 171
The 85-kilodalton phosphoprotein (pp85) of human herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles 169
Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in Cognitive Impairment Diseases 168
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 168
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 161
Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1 159
Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia 157
Serum From Advanced Heart Failure Patients Promotes Angiogenic Sprouting and Affects the Notch Pathway in Human Endothelial Cells 156
Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells 148
The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias 148
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 146
Multiple dye-doped NIR-emitting silica nanoparticles for both flow cytometry and in vivo imaging 145
The circulating levels of TRAIL are extremely low after delivery but rapidly recover in both mothers and newborns 144
Characterization of human herpesvirus 6 strains isolated from patients with exanthem subitum with or without cutaneous rash 138
Association of serum tumor necrosis factor-related apoptosis inducing ligand with body fat distribution as assessed by dual X-rays absorptiometry 137
Antiangiogenic activity of the MDM2 antagonist nutlin-3 137
Multimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities 137
Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-hodgkin's lymphoma xenografts 134
In vivo anti-lymphoma activity of an agonistic human recombinant anti-TRAIL-R2 minibody. 133
Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis 133
Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature 133
Nutlin-3 upregulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feed-back anti-apoptotic mechanism 131
MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC 131
The Sorafenib plus Nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of the FLT3 and p53 status 129
Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53(wild-type) JVM-2 But Not Towards p53(mutated) BJAB Leukemic Cells 129
Clinical perspectives of TRAIL: Insights into central nervous system disorders 129
Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease 129
null 128
Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA 128
Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment 128
CCR4+ skin-tropic phenotype as a feature of central memory CD8+ T cells in healthy subjects and psoriasis patients 128
TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release 127
Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol 127
In Vitro Characterization of Circulating Endothelial Progenitor Cells Isolated from Patients with Acute Coronary Syndrome 127
HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway 126
HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells 126
Association between thyroid hormones and TRAIL 126
Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults 126
The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): Study protocol for a randomized controlled trial 125
Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes 124
TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress 123
Actively targeted nanocarriers for drug delivery to cancer cells 123
Plasma levels of soluble NCAM in multiple sclerosis 122
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets 122
null 121
TNF-related apoptosis inducing ligand in ocular cancers and ocular diabetic complications 121
Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity 121
Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy 121
TRAIL and osteoprotegerin: a role in endothelial physiopathology? 120
GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients 120
The MDM2 inhibitor Nutlin-3 attenuates streptozotocin-induced diabetes mellitus and increases serum level of IL-12p40. 120
The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts 119
Circulating levels of TNF-related apoptosis inducing-ligand are decreased in patients with large adult-type granulosa cell tumors—implications for therapeutic potential 119
Human herpesvirus 6: A survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders 118
Elevated levels of TRAIL in systemic lupus erythematosus are associated to the presence of anti-SSA/SSB antibodies. 118
Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells 118
Molecular targets for selective killing of TRAIL-resistant leukemic cells. 118
Anti-leukemic activity of Dasatinib in both p53(wild-type) and p53 (mutated) B malignant cells. 118
Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL) 118
Cell-based therapies for diabetic complications. 118
COVID-19 and individual genetic susceptibility/receptivity: Role of ACE1/ACE2 genes, immunity, inflammation and coagulation. might the double x-chromosome in females be protective against SARS-COV-2 compared to the single x-chromosome in males? 118
Is there any role for tumour necrosis factor related apoptosis inducing ligand–osteoprotegerin (TRAIL–OPG) interaction in rheumatoid arthritis? 117
Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication 117
Circulating levels of frizzled-related protein (FRZB) are increased in patients with early rheumatoid arthritis and decrease in response to disease-modifying antirheumatic drugs. 117
State of art and recent developments of anti-cancer strategies based on TRAIL 117
A set of NF-κB-regulated microRNAs induces acquired TRAIL resistance in Lung cancer 117
Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye 117
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women 117
Human Herpesvirus 7 infection induces profound cell cycle perturbations coupled to disregulation of cdc2 and cyclin B and polyploidization of CD4+ T Cells 116
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells 116
Pegylated TRAIL retains anti-leukemic cytotoxicity and exhibits improved signal transduction activity with respect to TRAIL 115
Hydrogen sulfide down-regulates the expression and release of osteoprotegerin (OPG) by vascular endothelial cells 115
Mesenchymal stem cells display hepato-protective activity in lymphoma bearing xenografts 115
Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis 115
Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70 114
Increased frequency of activated CD8+ T cell effectors in patients with psoriatic arthritis 114
Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells 112
Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity 112
Cloning, restriction endonuclease mapping and partial sequence analysis of the genome of human herpesvirus 7 strain JI 112
Circulating TRAIL shows a significant post-partum decline associated to stressful conditions. 112
JCV plus Patients with Inflammatory Bowel Disease show elevated plasma levels of MIG and SCF 112
Involvement of TRAIL/TRAIL-receptors in human intestinal cell differentiation 111
Human herpesvirus type 7 in Hodgkin's disease 111
TRAIL, a New Weapon against Neointimal Hyperplasia 111
Context-dependent function of ROS in the vascular endothelium: The role of the Notch pathway and shear stress 111
MDM2 antagonist Nutlin-3 suppresses the proliferation and differentiation of human pre-osteoclasts through a p53-dependent pathway 109
Osteoprotegerin induces morphological and functional alterations in mouse pancreatic islets. 109
The tumour necrosis factor-related apoptosis inducing ligand-osteoprotegerin system in limited systemic sclerosis: a new disease marker? 109
MDM4 (MDMX) is overexpressed in chronic lymphocytic leukaemia (CLL) and marks a subset of p53wild-type CLL with a poor cytotoxic response to Nutlin-3. 108
Soluble TRAIL does not impair the anti-osteoclastic activity of osteoprotegerin: Letter to the editor 107
Levels of circulating TNF-related apoptosis-inducing ligand in celiac disease 106
Engagement of CD28 modulates CXC chemokine receptor 4 surface expression in both resting and CD3-stimulated CD4+ T cells 106
Human Colostrum and Breast Milk Contain High Levels of TNF-Related Apoptosis-Inducing Ligand (TRAIL). 106
The calendar of cytokines: Seasonal variation of circulating cytokines in chronic venous insufficiency 106
Merkel-cell polyomavirus (MCPyV) is rarely associated to B-chronic lymphocytic leukemia (1 out of 50) samples and occurs late in the natural history of the disease 106
Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells 105
Totale 12.694
Categoria #
all - tutte 123.753
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 123.753


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20203.887 0 0 0 0 440 678 655 658 520 542 234 160
2020/20214.565 292 379 171 560 344 475 240 541 147 671 469 276
2021/20222.870 87 314 220 115 161 164 175 165 101 233 334 801
2022/20232.687 296 131 95 311 408 394 116 245 358 48 160 125
2023/20241.451 162 182 53 38 105 201 45 148 30 30 59 398
2024/20252.056 214 192 533 310 807 0 0 0 0 0 0 0
Totale 27.391