PIGNANI, Silvia

PIGNANI, Silvia  

Dipartimento di Scienze della vita e biotecnologie  

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Risultati 1 - 13 di 13 (tempo di esecuzione: 0.011 secondi).
Titolo Data di pubblicazione Autore(i) File
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 2018 Pignani, Silvia; Todaro, Alice; Ferrarese, Mattia; Marchi, Saverio; Lombardi, Silvia; Balestra, D...ario; Pinton, Paolo; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes 2016 Barbon, Elena; Pignani, Silvia; Branchini, Alessio; Bernardi, Francesco; Pinotti, Mirko; Bovolent...a, Matteo
Base and Prime editing of DNA as a new therapeutic option for Hemophilia A 2022 Tonetto, Elena; Pignani, Silvia; Roman, Giacomo; Follenzi, Antonia; Bernardi, Francesco; Liu, Dav...id; Pinotti, Mirko; Balestra, Dario file con accesso da definire
CRISPR activation on coagulation F7 or F8 promoters potentiate trascriptional activity in the normal and mutated gene context 2019 Pignani, Silvia; Zappaterra, Federico; Barbon, Elena; Bovolenta, Matteo; Bernardi, Francesco; Bra...nchini, Alessio; Pinotti, Mirko
Engineered transcription factors (TALE-TF) as potential therapeutic strategy for coagulation factor deficiencies caused by promoter mutations 2015 Barbon, E; Pignani, S; Branchini, A; Bernardi, F; Pinotti, M; Bovolenta, M file con accesso da definire
Exploring chaperone-like compounds as innovative therapeutic correction approach for factor IX missense mutations causing type I Haemophilia B 2017 Pignani, S; Todaro, A; Ferrarese, M; Marchi, S; Lombardi, S; Pinton, P; Bernardi, F; Pinotti, M; ...Branchini, A
Exploring chaperone-like compounds as innovative therapeutic strategy for Hemophilia B 2017 Pignani, S; Ferrarese, M; Lombardi, S; Marchi, S; Todaro, A; Pinton, P; Bernardi, F; Pinotti, M; ...Branchini, A file con accesso da definire
Modulation at transcriptional and post-translational level to develop therapeutic approaches for coagulation factor deficiencies 2018 Pignani, Silvia
New Genome Editing Approaches: Base And Prime Editing To Revert Hemophilia A-Causing Point Mutations 2022 Tonetto, E.; Pignani, S.; Roman, G.; Follenzi, A.; Bernardi, F.; Liu, D.; Pinotti, M.; Balestra, D. file con accesso da definire
Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts 2019 Pignani, Silvia; Zappaterra, Federico; Barbon, Elena; Follenzi, Antonia; Bovolenta, Matteo; Berna...rdi, Francesco; Branchini, Alessio; Pinotti, Mirko
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 2018 Ferrarese, Mattia; Pignani, Silvia; Lombardi, Silvia; Balestra, Dario; Bernardi, Francesco; Pinot...ti, Mirko; Branchini, Alessio
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 2018 Pignani, Silvia; Todaro, Alice; Ferrarese, Mattia; Marchi, Saverio; Lombardi, Silvia; Balestra, D...ario; Pinton, Paolo; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 2018 Pignani, S; Todaro, A; Ferrarese, M; Marchi, S; Lombardi, S; Balestra, D; Pinton, P; Bernardi, F;... Pinotti, M; Branchini, A