The antidiuretic drug desmopressin acetate (DDAVP) is a cyclic peptide drug commonly administered via the nose, given its very poor oral bioavailability. Here, we studied a preservative-free immediate release powder formulation for nasal administration of desmopressin as an alternative to conventional liquid nasal formulations.
In vitro and in vivo study of a desmopressin nasal powder
COLOMBO, Gaia;DALPIAZ, Alessandro;FERRARO, Luca Nicola;BORTOLOTTI, Fabrizio
2007
Abstract
The antidiuretic drug desmopressin acetate (DDAVP) is a cyclic peptide drug commonly administered via the nose, given its very poor oral bioavailability. Here, we studied a preservative-free immediate release powder formulation for nasal administration of desmopressin as an alternative to conventional liquid nasal formulations.File in questo prodotto:
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