Recent data shed light on two novel aspects of the mitochondria-Ca2+ liaison. First, it was extensively investigated how Ca2+ handling is controlled by mitochondrial shape, and positioning; a playground also of cell death and survival regulation. On the other hand, significant progress has been made to explore how intra- and near-mitochondrial Ca2+ signals modify mitochondrial morphology and cellular distribution. Here, we shortly summarize these advances and provide a model of Ca2+-mitochondria interactions.

Mitochondrial dynamics and Ca2+ signaling

SZABADKAI, Gyorgy;SIMONI, Anna Maria;BIANCHI, Katiuscia;DE STEFANI, Diego;LEO, Sara;WIECKOWSKI, Mariusz;RIZZUTO, Rosario
2006

Abstract

Recent data shed light on two novel aspects of the mitochondria-Ca2+ liaison. First, it was extensively investigated how Ca2+ handling is controlled by mitochondrial shape, and positioning; a playground also of cell death and survival regulation. On the other hand, significant progress has been made to explore how intra- and near-mitochondrial Ca2+ signals modify mitochondrial morphology and cellular distribution. Here, we shortly summarize these advances and provide a model of Ca2+-mitochondria interactions.
2006
Szabadkai, Gyorgy; Simoni, Anna Maria; Bianchi, Katiuscia; DE STEFANI, Diego; Leo, Sara; Wieckowski, Mariusz; Rizzuto, Rosario
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/518912
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