The enantioselective resolution of the racemic 1-heteroaryl- and 1-arylethanols 1a-h via microbial oxidation with Bacillus stearothermophilus to give the R-enantiomers with high enantiomeric excesses is described. The kinetic resolution of 1-(2-thienyl)ethanol 1b by oxidation with Acinetobacter calcoaceticus anitrat to S-enantiomer (ee 100%) is also reported. © 1993.

Microbial oxidation with Bacillus stearothermophilus: high enantioselective resolution of 1-heteroaryl and 1-aryl alcohols

FANTIN, Giancarlo;FOGAGNOLO, Marco;MEDICI, Alessandro;PEDRINI, Paola;
1993

Abstract

The enantioselective resolution of the racemic 1-heteroaryl- and 1-arylethanols 1a-h via microbial oxidation with Bacillus stearothermophilus to give the R-enantiomers with high enantiomeric excesses is described. The kinetic resolution of 1-(2-thienyl)ethanol 1b by oxidation with Acinetobacter calcoaceticus anitrat to S-enantiomer (ee 100%) is also reported. © 1993.
1993
Fantin, Giancarlo; Fogagnolo, Marco; Medici, Alessandro; Pedrini, Paola; S., Poli; F., Gardini
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/462442
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