In the presence of Mg2+, the formation of actin filaments is hindered by glyceraldehyde-3-phosphate dehydrogenase. This effect, which increases with the square of Mg2+ concentration, is counteracted by 0.15 M KCl. Thus KCl, at concentrations found in the intracellular compartment, appears to be strictly required for the correct formation of actin filaments in all tissues in which the glyceraldehyde-phosphate dehydrogenase concentration is high.

On an Mg2+-dependent interaction of actin with glyceraldehyde-phosphate dehydrogenase The fundamental role of KCl in the organization of F-actin

LANZARA, Vincenzo
Primo
;
GRAZI E.
Ultimo
1987

Abstract

In the presence of Mg2+, the formation of actin filaments is hindered by glyceraldehyde-3-phosphate dehydrogenase. This effect, which increases with the square of Mg2+ concentration, is counteracted by 0.15 M KCl. Thus KCl, at concentrations found in the intracellular compartment, appears to be strictly required for the correct formation of actin filaments in all tissues in which the glyceraldehyde-phosphate dehydrogenase concentration is high.
1987
Lanzara, Vincenzo; Grazi, E.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/462012
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