DNA from 20 Italian haemophilia B patients was analysed by the Southern blotting technique and hybridisation to a factor IX cDNA probe. A large deletion of factor IX gene was detected in one patient with antibodies to the infused factor; the EcoRI pattern of the other 19 subjects examined was normal.

Gene deletion in an Italian haemophilia B subject

F. BERNARDI
Primo
;
DEL SENNO L
Secondo
;
GAMBARI R;CONCONI F;
1985

Abstract

DNA from 20 Italian haemophilia B patients was analysed by the Southern blotting technique and hybridisation to a factor IX cDNA probe. A large deletion of factor IX gene was detected in one patient with antibodies to the infused factor; the EcoRI pattern of the other 19 subjects examined was normal.
1985
Bernardi, F.; DEL SENNO, L; Barbieri, R; Buzzoni, D; Gambari, R; Marchetti, G; Conconi, F; Panicucci, F; Positano, M; Pitruzzello, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/460478
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