The binding properties of quercetin toward chloride anions were investigated by means of1H-NMR,13C-NMR, and electrospray ionization mass spectrometry (ESI-MS) measurements, as well as computational calculations. The results indicate that quercetin behaves primarily as a ditopic receptor with the binding site of the B ring that exhibits stronger chloride affinity compared to the A ring. However, these sites are stronger receptors than those of catechol and resorcinol because of their conjugation with the carbonyl group located on the C ring. The 1:1 and 1:2 complexation of this flavonoid with Cl− was also supported by ESI mass spectrometry.

Native quercetin as a chloride receptor in an organic solvent

Mohamed Lamin Abdi Bellau;Olga Bortolini;Giancarlo Fantin
;
Marco Fogagnolo;Daniele Ragno;
2018

Abstract

The binding properties of quercetin toward chloride anions were investigated by means of1H-NMR,13C-NMR, and electrospray ionization mass spectrometry (ESI-MS) measurements, as well as computational calculations. The results indicate that quercetin behaves primarily as a ditopic receptor with the binding site of the B ring that exhibits stronger chloride affinity compared to the A ring. However, these sites are stronger receptors than those of catechol and resorcinol because of their conjugation with the carbonyl group located on the C ring. The 1:1 and 1:2 complexation of this flavonoid with Cl− was also supported by ESI mass spectrometry.
ABDI BELLAU, Mohamed Lamin; Bortolini, Olga; Fantin, Giancarlo; Fogagnolo, Marco; Ragno, Daniele; Delso, Ignacio; Merino, Pedro
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2397401
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