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EnglishThe prognosis of neuroendocrine neoplasms (NENs) is widely variable and has been shown to associate with several tissue- and blood-based biomarkers in different settings. The identification of prognostic factors predicting NEN outcome is of paramount importance to select the best clinical management for these patients. Prognostic markers have been intensively investigated, also taking advantage of the most modern techniques, in the perspective of personalized medicine and appropriate resource utilization. This review summarizes the available data on the possible role of circulating tumor cells and microRNAs as prognostic markers in NENs.
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| Data di pubblicazione: | 2017 | |
| Titolo: | Circulating tumor cells and miRNA as prognostic markers in neuroendocrine neoplasms | |
| Autori: | Zatelli, Maria Chiara; Grossrubatscher, Erika Maria; Guadagno, Elia; Sciammarella, Concetta; Faggiano, Antongiulio; Colao, Annamaria | |
| Rivista: | ENDOCRINE-RELATED CANCER | |
| Parole Chiave: | neuroendocrine tumors, circulating biomarkers, prognosis, miRNA,CTC | |
| Abstract: | The prognosis of neuroendocrine neoplasms (NENs) is widely variable and has been shown to associate with several tissue- and blood-based biomarkers in different settings. The identification of prognostic factors predicting NEN outcome is of paramount importance to select the best clinical management for these patients. Prognostic markers have been intensively investigated, also taking advantage of the most modern techniques, in the perspective of personalized medicine and appropriate resource utilization. This review summarizes the available data on the possible role of circulating tumor cells and microRNAs as prognostic markers in NENs. | |
| Digital Object Identifier (DOI): | 10.1530/ERC-17-0091 | |
| Handle: | http://hdl.handle.net/11392/2368370 | |
| Appare nelle tipologie: | 03.1 Articolo su rivista |
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