Aim. To evaluate the degree of correlation between a dental parameter of immediate clinical relevance (overjet) with skeletal (ANB angle) and dentoskeletal parameters such as the IMPA angle and upper incisor-bispinal angle. Materials and Methods. A sample of 42 subjects, all in complete permanent dentition and without a history of orthodontic treatment or systemic pathologies, was subdivided into 2 groups: group 1 consisted of 25 subjects with ANB angle 0◦–4◦ (skeletal class I), and group 2 was made up of 17 subjects with ANB angle >4◦ (skeletal class II). Each subject underwent cone-beam computed tomography (CBCT). For each right and left CBCT, the following parameters were measured: (1) ANB, (2) OJ (overjet), (3) IMPA angle, and (4) upper incisor- bispinal angle (U1/ANS-PNS). Results. Analysis of the entire sample revealed that both right and left overjets were correlated in a statistically significant fashion (P < 0.001) with ANB. No correlation between overjet and IMPA emerged, while a weak correlation between overjet and the left U1-bispinal plane was ascertained. Conclusions. Overjet may be a reliable predictor of ANB, and to a lesser extent the U1-bispinal plane, particularly in skeletal class II.