Various yeast and mould strains were tested in the microbial reduction of methyl-substituted bicyclo[3.2.0]hept-3-en-6-ones 1a-c. The endo-alcohols 2a-c were obtained with good yields and enantiomeric excess. Lower yields are described for the exo-alcohols 3a-c which are normally enantiomerically pure. Comparisons with microbial reduction of bicyclo[3.2.0]hept-2-en-6-one 1d and bicyclo[3.3.0]oct-7-en-2-one 1e are also reported.

Microbial reduction of methyl-substituted bicyclo[3.2.0]hept-3-en-6-ones: a screening to the homochiral endo- and exo-alcohols

FANTIN, Giancarlo;FOGAGNOLO, Marco;MEDICI, Alessandro;PEDRINI, Paola;
1996

Abstract

Various yeast and mould strains were tested in the microbial reduction of methyl-substituted bicyclo[3.2.0]hept-3-en-6-ones 1a-c. The endo-alcohols 2a-c were obtained with good yields and enantiomeric excess. Lower yields are described for the exo-alcohols 3a-c which are normally enantiomerically pure. Comparisons with microbial reduction of bicyclo[3.2.0]hept-2-en-6-one 1d and bicyclo[3.3.0]oct-7-en-2-one 1e are also reported.
1996
Fantin, Giancarlo; Fogagnolo, Marco; Medici, Alessandro; Pedrini, Paola; E., Marotta; M., Monti; P., Righi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1204868
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