MALFACINI, Davide
MALFACINI, Davide
Dipartimento di Scienze mediche
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands
file con accesso da definire2014 S., Corrado; C., Sorbi; A., Tait; U. M., Battisti; Camarda, Valeria; Malfacini, Davide; Calo', Girolamo; L., Brasili
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies
file con accesso da definire2014 Ruzza, Chiara; L., del Zoppo; Malfacini, Davide; Pela', Michela; Trapella, Claudio; P., Grieco; Salvadori, Severo; Calo', Girolamo; Guerrini, Remo
A Multi-Angle Approach to Predict Peptide-GPCR Complexes: The N/OFQ-NOP System as a Successful AlphaFold Application Case Study
file con accesso da definire2024 Ciancetta, Antonella; Malfacini, Davide; Gozzi, Matteo; Marzola, Erika; Camilotto, Riccardo; Calò, Girolamo; Guerrini, Remo
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ
file con accesso da definire2014 Guerrini, Remo; Marzola, Erika; Trapella, Claudio; Pela', Michela; Molinari, Stefano; Cerlesi, Maria Camilla; Malfacini, Davide; Rizzi, Anna; Salvadori, Severo; Calo', Girolamo
Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111
file con accesso da definire2013 Marti, Matteo; Mela, Flora; Budri, Mirco; Volta, Mattia; Malfacini, Davide; Molinari, Stefano; N. T., Zaveri; S., Ronzoni; P., Petrillo; Calo', Girolamo; Morari, Michele
Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic- versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands
2016 Asth, L; Ruzza, Chiara; Malfacini, Davide; Medeiros, I; Guerrini, Remo; Zaveri, N. T; Gavioli, E. C; Calo', Girolamo
Characterisation of the novel mixed Mu-NOP peptide ligand dermorphin-N/OFQ (DeNo)
2016 Bird, Mark F.; Camilla Cerlesi, Maria; Brown, Mark; Malfacini, Davide; Vezzi, Vanessa; Molinari, Paola; Micheli, Laura; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Guerrini, Remo; Calo', Girolamo; Lambert, David G.
Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor
file con accesso da definire2014 Tanila Ben, Haddou; Malfacini, Davide; Calo', Girolamo; Mario D., Aceto; Louis S., Harris; John R., Traynor; Andrew, Coop; Helmut, Schmidhammer; Mariana, Spetea
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists
2021 Azevedo Neto, J.; Ruzza, C.; Sturaro, C.; Malfacini, D.; Pacifico, S.; Zaveri, N. T.; Calo, G.
In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl
2022 Bilel, Sabrine; Azevedo Neto, Joaquim; Arfè, Raffaella; Tirri, Micaela; Gaudio, Rosa Maria; Fantinati, Anna; Bernardi, Tatiana; Boccuto, Federica; Marchetti, Beatrice; Corli, Giorgia; Serpelloni, Giovanni; De-Giorgio, Fabio; Malfacini, Davide; Trapella, Claudio; Calo', Girolamo; Marti, Matteo
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative
file con accesso da definire2015 Ruzza, Chiara; Rizzi, Anna; Malfacini, Davide; Pulga, Alice; Pacifico, Salvatore; Salvadori, Severo; Trapella, Claudio; Reinscheid, Rainer K; Calo', Girolamo; Guerrini, Remo
In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives
file con accesso da definire2014 Rizzi, Anna; Malfacini, Davide; Cerlesi, Maria Camilla; Ruzza, Chiara; Marzola, Erika; M. F., Bird; D. J., Rowbotham; Salvadori, Severo; Guerrini, Remo; D. G., Lambert; Calo', Girolamo
In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant
file con accesso da definire2015 Ruzza, Chiara; Rizzi, Anna; Malfacini, Davide; Molinari, Stefano; Giuliano, Claudio; Lovati, Emanuela; Pietra, Claudio; Calo', Girolamo
In vitro and in vivo study of butyrylfentanyl and 4‐fluorobutyrylfentanyl in female and male mice: Role of the CRF1 receptor in cardiorespiratory impairment
file con accesso da definire2024 Bilel, Sabrine; Azevedo Neto, Joaquim; Tirri, Micaela; Corli, Giorgia; Bassi, Marta; Fantinati, Anna; Serpelloni, Giovanni; Malfacini, Davide; Trapella, Claudio; Calo', Girolamo; Marti, Matteo
In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations
file con accesso da definire2016 Ferrari, Federica; Cerlesi, Maria Camilla; Malfacini, Davide; Asth, Laila; Gavioli, Elaine C; Journigan, Blair V; Kamakolanu, Uma Gayathri; Meyer, Michael E; Yasuda, Dennis; Polgar, Willma E; Rizzi, Anna; Guerrini, Remo; Ruzza, Chiara; Zaveri, Nurulain T; Calo', Girolamo
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403
file con accesso da definire2017 Ferrari, Federica; Malfacini, Davide; Journigan, Blair V.; Bird, Mark F.; Trapella, Claudio; Guerrini, Remo; Lambert, David G.; Calo', Girolamo; Zaveri, Nurulain T.
NOP receptor pharmacological profile – A dynamic mass redistribution study
2018 Malfacini, Davide; Simon, Katharina; Trapella, Claudio; Guerrini, Remo; Zaveri, Nurulain T.; Kostenis, Evi; Calo, Girolamo
Novel ligands and assays for nociceptin/orphanin FQ and classical opioid receptors
2015 Malfacini, Davide
Pharmacological Assays for Investigating the NOP Receptor
2019 Malfacini, Davide; Calo', Girolamo
Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist
file con accesso da definire2016 Rizzi, Anna; Cerlesi, Maria Camilla; Ruzza, Chiara; Malfacini, Davide; Ferrari, Federica; Bianco, Sara; Costa, Tommaso; Guerrini, Remo; Trapella, Claudio; Calo', Girolamo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands | 2014 | S., Corrado; C., Sorbi; A., Tait; U. M., Battisti; Camarda, Valeria; Malfacini, Davide; Calo', Gi...rolamo; L., Brasili | file con accesso da definire |
| [D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies | 2014 | Ruzza, Chiara; L., del Zoppo; Malfacini, Davide; Pela', Michela; Trapella, Claudio; P., Grieco; S...alvadori, Severo; Calo', Girolamo; Guerrini, Remo | file con accesso da definire |
| A Multi-Angle Approach to Predict Peptide-GPCR Complexes: The N/OFQ-NOP System as a Successful AlphaFold Application Case Study | 2024 | Ciancetta, Antonella; Malfacini, Davide; Gozzi, Matteo; Marzola, Erika; Camilotto, Riccardo; Calò..., Girolamo; Guerrini, Remo | file con accesso da definire |
| A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ | 2014 | Guerrini, Remo; Marzola, Erika; Trapella, Claudio; Pela', Michela; Molinari, Stefano; Cerlesi, Ma...ria Camilla; Malfacini, Davide; Rizzi, Anna; Salvadori, Severo; Calo', Girolamo | file con accesso da definire |
| Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111 | 2013 | Marti, Matteo; Mela, Flora; Budri, Mirco; Volta, Mattia; Malfacini, Davide; Molinari, Stefano; N.... T., Zaveri; S., Ronzoni; P., Petrillo; Calo', Girolamo; Morari, Michele | file con accesso da definire |
| Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic- versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands | 2016 | Asth, L; Ruzza, Chiara; Malfacini, Davide; Medeiros, I; Guerrini, Remo; Zaveri, N. T; Gavioli, E.... C; Calo', Girolamo | |
| Characterisation of the novel mixed Mu-NOP peptide ligand dermorphin-N/OFQ (DeNo) | 2016 | Bird, Mark F.; Camilla Cerlesi, Maria; Brown, Mark; Malfacini, Davide; Vezzi, Vanessa; Molinari, ...Paola; Micheli, Laura; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Guerrini, Remo; Calo', Girolamo; Lambert, David G. | |
| Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor | 2014 | Tanila Ben, Haddou; Malfacini, Davide; Calo', Girolamo; Mario D., Aceto; Louis S., Harris; John R...., Traynor; Andrew, Coop; Helmut, Schmidhammer; Mariana, Spetea | file con accesso da definire |
| Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists | 2021 | Azevedo Neto, J.; Ruzza, C.; Sturaro, C.; Malfacini, D.; Pacifico, S.; Zaveri, N. T.; Calo, G. | |
| In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl | 2022 | Bilel, Sabrine; Azevedo Neto, Joaquim; Arfè, Raffaella; Tirri, Micaela; Gaudio, Rosa Maria; Fanti...nati, Anna; Bernardi, Tatiana; Boccuto, Federica; Marchetti, Beatrice; Corli, Giorgia; Serpelloni, Giovanni; De-Giorgio, Fabio; Malfacini, Davide; Trapella, Claudio; Calo', Girolamo; Marti, Matteo | |
| In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative | 2015 | Ruzza, Chiara; Rizzi, Anna; Malfacini, Davide; Pulga, Alice; Pacifico, Salvatore; Salvadori, Seve...ro; Trapella, Claudio; Reinscheid, Rainer K; Calo', Girolamo; Guerrini, Remo | file con accesso da definire |
| In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives | 2014 | Rizzi, Anna; Malfacini, Davide; Cerlesi, Maria Camilla; Ruzza, Chiara; Marzola, Erika; M. F., Bir...d; D. J., Rowbotham; Salvadori, Severo; Guerrini, Remo; D. G., Lambert; Calo', Girolamo | file con accesso da definire |
| In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant | 2015 | Ruzza, Chiara; Rizzi, Anna; Malfacini, Davide; Molinari, Stefano; Giuliano, Claudio; Lovati, Eman...uela; Pietra, Claudio; Calo', Girolamo | file con accesso da definire |
| In vitro and in vivo study of butyrylfentanyl and 4‐fluorobutyrylfentanyl in female and male mice: Role of the CRF1 receptor in cardiorespiratory impairment | 2024 | Bilel, Sabrine; Azevedo Neto, Joaquim; Tirri, Micaela; Corli, Giorgia; Bassi, Marta; Fantinati, A...nna; Serpelloni, Giovanni; Malfacini, Davide; Trapella, Claudio; Calo', Girolamo; Marti, Matteo | file con accesso da definire |
| In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations | 2016 | Ferrari, Federica; Cerlesi, Maria Camilla; Malfacini, Davide; Asth, Laila; Gavioli, Elaine C; Jou...rnigan, Blair V; Kamakolanu, Uma Gayathri; Meyer, Michael E; Yasuda, Dennis; Polgar, Willma E; Rizzi, Anna; Guerrini, Remo; Ruzza, Chiara; Zaveri, Nurulain T; Calo', Girolamo | file con accesso da definire |
| In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 | 2017 | Ferrari, Federica; Malfacini, Davide; Journigan, Blair V.; Bird, Mark F.; Trapella, Claudio; Guer...rini, Remo; Lambert, David G.; Calo', Girolamo; Zaveri, Nurulain T. | file con accesso da definire |
| NOP receptor pharmacological profile – A dynamic mass redistribution study | 2018 | Malfacini, Davide; Simon, Katharina; Trapella, Claudio; Guerrini, Remo; Zaveri, Nurulain T.; Kost...enis, Evi; Calo, Girolamo | |
| Novel ligands and assays for nociceptin/orphanin FQ and classical opioid receptors | 2015 | Malfacini, Davide | |
| Pharmacological Assays for Investigating the NOP Receptor | 2019 | Malfacini, Davide; Calo', Girolamo | |
| Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist | 2016 | Rizzi, Anna; Cerlesi, Maria Camilla; Ruzza, Chiara; Malfacini, Davide; Ferrari, Federica; Bianco,... Sara; Costa, Tommaso; Guerrini, Remo; Trapella, Claudio; Calo', Girolamo | file con accesso da definire |