| Nome |
# |
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Non-invasive Prenatal Testing Using Fetal DNA, file e309ade3-bdaf-3969-e053-3a05fe0a2c94
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714
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Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis, file e309ade0-f854-3969-e053-3a05fe0a2c94
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298
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Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports, file e309ade2-140d-3969-e053-3a05fe0a2c94
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206
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Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia, file e309ade2-4e76-3969-e053-3a05fe0a2c94
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151
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Ground state naïve pluripotent stem cells and CRISPR/Cas9 gene correction for β-thalassemia, file e309ade1-8cb9-3969-e053-3a05fe0a2c94
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141
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An Aγ-globin G->A gene polymorphism associated with β(0)39 thalassemia globin gene and high fetal hemoglobin production, file e309ade1-7733-3969-e053-3a05fe0a2c94
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140
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Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions, file e309ade2-d99c-3969-e053-3a05fe0a2c94
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123
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BCL11A mRNA targeting by miR-210: A possible network regulating γ-globin gene expression, file e309ade1-8625-3969-e053-3a05fe0a2c94
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110
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Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review), file e309ade2-1508-3969-e053-3a05fe0a2c94
|
99
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Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells, file e309ade2-4e78-3969-e053-3a05fe0a2c94
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97
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Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance, file e309ade3-a96d-3969-e053-3a05fe0a2c94
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94
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MicroRNAs and Long Non-coding RNAs in Genetic Diseases, file e309ade2-1ab8-3969-e053-3a05fe0a2c94
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87
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Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin, file e309ade0-a5be-3969-e053-3a05fe0a2c94
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83
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A validated cellular biobank for β-thalassemia, file e309ade0-ee58-3969-e053-3a05fe0a2c94
|
78
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Differential Effects of Angelicin Analogues on NF-kB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells, file e309ade1-8832-3969-e053-3a05fe0a2c94
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72
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Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells, file e309ade0-ad71-3969-e053-3a05fe0a2c94
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70
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New insights into the Shwachman-Diamond Syndrome-related haematological disorder: Hyper-activation of mTOR and STAT3 in leukocytes, file e309ade0-ef51-3969-e053-3a05fe0a2c94
|
70
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Recent trends in the gene therapy of β-thalassemia, file e309ade0-a34c-3969-e053-3a05fe0a2c94
|
67
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Regulation of IL-8 gene expression in gliomas by microRNA miR-93, file e309ade0-a781-3969-e053-3a05fe0a2c94
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67
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A peptide nucleic acid against microrna miR-145-5p enhances the expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells, file e309ade1-a84d-3969-e053-3a05fe0a2c94
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66
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Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene, file e309ade2-2c03-3969-e053-3a05fe0a2c94
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66
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Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA), file e309ade2-1293-3969-e053-3a05fe0a2c94
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65
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Efficient Delivery of MicroRNA and AntimiRNA Molecules Using an Argininocalix[4]arene Macrocycle, file e309ade2-84e3-3969-e053-3a05fe0a2c94
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64
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MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells, file e309ade2-d9f2-3969-e053-3a05fe0a2c94
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61
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Isothermal circular-strand-displacement polymerization of DNA and microRNA in digital microfluidic devices, file e309ade3-1d09-3969-e053-3a05fe0a2c94
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61
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Enhancing the expression of CFTR using antisense molecules against MicroRNA miR-145-5p, file e309ade2-794c-3969-e053-3a05fe0a2c94
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59
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miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma, file e309ade0-de82-3969-e053-3a05fe0a2c94
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58
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Production of β-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous β039 thalassemia patients, file e309ade0-f426-3969-e053-3a05fe0a2c94
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58
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Peptide nucleic acid-based targeting of microRNAs: possible therapeutic applications for glioblastoma, file e309ade2-8d15-3969-e053-3a05fe0a2c94
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58
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Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology, file e309ade2-5220-3969-e053-3a05fe0a2c94
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57
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Pro‑apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro, file e309ade2-ef0e-3969-e053-3a05fe0a2c94
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57
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Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae, file e309ade0-d970-3969-e053-3a05fe0a2c94
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56
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Generation and characterization of a transgenic mouse carrying a functional human β-globin gene with the IVSI-6 thalassemia mutation, file e309ade0-a54c-3969-e053-3a05fe0a2c94
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55
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Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells, file e309ade2-d6a6-3969-e053-3a05fe0a2c94
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54
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|
Treatment of human airway epithelial Calu-3 cells with a peptide-nucleic acid (PNA) targeting the microRNA miR-101-3p is associated with increased expression of the cystic fibrosis Transmembrane Conductance Regulator () gene, file f8818e72-4359-45e8-bda1-5ad1b8cc735f
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54
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|
Enzymatic Spermine Metabolites Induce Apoptosis Associated with Increase of p53, caspase-3 and miR-34a in Both Neuroblastoma Cells, SJNKP and the N-Myc-Amplified Form IMR5, file e309ade4-9397-3969-e053-3a05fe0a2c94
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48
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Tackling the COVID-19 “cytokine storm” with microRNA mimics directly targeting the 3’UTR of pro-inflammatory mRNAs, file e309ade3-3cc7-3969-e053-3a05fe0a2c94
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47
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Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line, file e309ade2-82f2-3969-e053-3a05fe0a2c94
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46
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|
Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis, file e309ade2-d08c-3969-e053-3a05fe0a2c94
|
43
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Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma, file e309ade2-15b5-3969-e053-3a05fe0a2c94
|
41
|
|
Circulating microRNAs and liquid biopsy: murine xenograft models for technical validation of clinical protocols, file e309ade4-e1ec-3969-e053-3a05fe0a2c94
|
41
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|
Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters, file e309ade2-5134-3969-e053-3a05fe0a2c94
|
36
|
|
UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation, file e309ade2-1ad9-3969-e053-3a05fe0a2c94
|
35
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Expression of γ-globin genes in β-thalassemia patients treated with sirolimus: results from a pilot clinical trial (Sirthalaclin), file 330010a8-57ab-464b-ac76-8393bc420f74
|
27
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|
Teaching during COVID-19 pandemic in practical laboratory classes of applied biochemistry and pharmacology: A validated fast and simple protocol for detection of SARS-CoV-2 Spike sequences, file 54a3abb9-d553-400e-b399-8faf8b175616
|
27
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Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein, file e309ade4-a21c-3969-e053-3a05fe0a2c94
|
22
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A PNA-based masking strategy for CFTR upregulation by targeting miR-145-5p binding sites of CFTR mRNA, file e309ade4-e1d6-3969-e053-3a05fe0a2c94
|
22
|
|
A peptide nucleic acid (PNA) masking the miR-145-5p binding site of the 3’UTR of the cystic fibrosis transmembrane conductance regulator (CFTR) mRNA enhances CFTR expression in Calu-3 cells, file e309ade5-219c-3969-e053-3a05fe0a2c94
|
20
|
|
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222, file e309ade3-1797-3969-e053-3a05fe0a2c94
|
16
|
|
Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation., file e309ade0-b02c-3969-e053-3a05fe0a2c94
|
15
|
|
Epigenetic changes as a common trigger of muscle weakness in congenital myopathies, file e309ade3-17ce-3969-e053-3a05fe0a2c94
|
14
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|
Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β039-Globin Gene Editing and Induction of Fetal Hemoglobin, file 9d5c4855-ca44-4b1e-81e0-0497d5378d9a
|
13
|
|
Efficient CRISPR-Cas9-based genome editing of β-globin gene on erythroid cells from homozygous β039-thalassemia patients, file 9da7183c-325f-47c5-ad31-8c0adf3f55bf
|
13
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Down-regulation of LYAR is associated with induction of fetal hemoglobin in mithramycin-treated erythroid cells, file e309ade5-2cca-3969-e053-3a05fe0a2c94
|
13
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Therapy for Cystic Fibrosis Caused by Nonsense Mutations, file e309ade0-e68c-3969-e053-3a05fe0a2c94
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12
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Synthesis and biological evaluation of new antitubulin agents containing 2-(30,40,50-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold, file e309ade2-9b91-3969-e053-3a05fe0a2c94
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11
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A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1, file e309ade4-d2e9-3969-e053-3a05fe0a2c94
|
11
|
|
Up-regulation of miR-34a-3p and miR-744-3p is associated with down-regulation of PTEN in lymphoblastoid cells from Shwachman-Diamond Syndrome patients, file e309ade4-d87f-3969-e053-3a05fe0a2c94
|
10
|
|
A distinctive microrna (Mirna) signature in the blood of colorectal cancer (crc) patients at surgery, file e309ade2-d96f-3969-e053-3a05fe0a2c94
|
9
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|
Treatment of erythroid precursor cells from β‐thalassemia patients with cinchona alkaloids: Induction of fetal hemoglobin production, file e309ade5-17a9-3969-e053-3a05fe0a2c94
|
9
|
|
A peptide nucleic acid targeting the acpP gene of Pseudomonas aeruginosa inhibits bacterial induced biological alterations in cystic fibrosis cells, file e309ade5-11c3-3969-e053-3a05fe0a2c94
|
8
|
|
A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs, file 8580432b-00cf-4c35-9b4d-8db5dc11d407
|
7
|
|
Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti-tubulin tetrahydrothieno[2,3-c]pyridine derivative and a peptide nucleic acid targeting miR-221-3p, file e309ade4-d2eb-3969-e053-3a05fe0a2c94
|
7
|
|
Sirolimus-mediated induction of fetal hemoglobin in beta-thalassemia: impact of the XmnI rs74482144 polymophism, file e309ade5-1100-3969-e053-3a05fe0a2c94
|
7
|
|
MicroRNAs miR-584-5p and miR-425-3p Are Up-Regulated in Plasma of Colorectal Cancer (CRC) Patients: Targeting with Inhibitor Peptide Nucleic Acids Is Associated with Induction of Apoptosis in Colon Cancer Cell Lines, file a6c2e50a-004e-4b13-a059-133d724200cc
|
6
|
|
Analysis of the miRNome as a possible tool for the detection of autologous blood transfusion misuse in sport, file e309ade5-10fe-3969-e053-3a05fe0a2c94
|
6
|
|
In vitro induction of interleukin-8 by SARS-CoV-2 Spike protein is inhibited in bronchial epithelial IB3-1 cells by a miR-93-5p agomiR, file e309ade5-1660-3969-e053-3a05fe0a2c94
|
6
|
|
Treatment of Human Glioblastoma U251 Cells with Sulforaphane and a Peptide Nucleic Acid (PNA) Targeting miR-15b-5p: Synergistic Effects on Induction of Apoptosis, file e309ade5-90a7-3969-e053-3a05fe0a2c94
|
6
|
|
Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β039-Globin Gene Editing and Induction of Fetal Hemoglobin, file f7b6e824-22ca-4600-899b-88c7114484c0
|
6
|
|
Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole Scaffold, file f887e2be-398f-43ba-b843-928abdb89536
|
6
|
|
Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β(0)-Thalassemia Families with High Fetal Hemoglobin Levels, file e309ade0-e064-3969-e053-3a05fe0a2c94
|
5
|
|
Differential effects on the miRNome of the treatment of human airway epithelial Calu-3 cells with peptide-nucleic acids (PNAs) targeting microRNAs miR-101-3p and miR-145-5p: Next generation sequencing datasets, file e309ade4-aafa-3969-e053-3a05fe0a2c94
|
5
|
|
Spermine metabolite, hydrogen peroxide and aldehyde, induce the apoptosis of neuroblastoma cells associated with increase of p53, Caspase-3 and miR-34a, file e309ade5-3173-3969-e053-3a05fe0a2c94
|
5
|
|
A Signature of Differentially Expressed Micrornas in Lymphoblastoid Cells from Shwachman-Diamond Syndrome Patients Indicates Possible Molecular Targets for Mirna Therapeutics, file e309ade5-9f9d-3969-e053-3a05fe0a2c94
|
5
|
|
A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs, file 25107cdf-6b9d-4a32-ad7a-0f7171474ccf
|
4
|
|
A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs, file 620f0aa5-0d1b-45ad-b2db-b53c8ca50249
|
4
|
|
Combined Treatment of Cancer Cells Using Allyl Palladium Complexes Bearing Purine-Based NHC Ligands and Molecules Targeting MicroRNAs miR-221-3p and miR-222-3p: Synergistic Effects on Apoptosis, file 93fe3a7e-8d7a-487f-bad5-4ddcad95f029
|
4
|
|
509 Cystic fibrosis transmembrane conductance regulator positively regulates angiotensin-converting enzyme 2 expression and SARS-CoV-2 viral entry into airway epithelial cells: Implications for patients with cystic fibrosis, file af773ed6-8a3c-4d7a-b2d7-e099c479d507
|
4
|
|
Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor, file e309ade0-28aa-3969-e053-3a05fe0a2c94
|
4
|
|
AGENTI TRASFETTANTI PER microRNA E antagomiRNA, file e309ade1-a46b-3969-e053-3a05fe0a2c94
|
4
|
|
Up-regulation of miR-34a-3p and miR-744-3p is associated with down-regulation of PTEN in lymphoblastoid cells from Shwachman-Diamond Syndrome patients, file e309ade2-9626-3969-e053-3a05fe0a2c94
|
4
|
|
Possible effects of sirolimus treatment on the long‑term efficacy of COVID‑19 vaccination in patients with β‑thalassemia: A theoretical perspective, file e309ade5-5a7d-3969-e053-3a05fe0a2c94
|
4
|
|
Effects of Sirolimus treatment on patients with β-Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4+ and CD8+ T cells, file 01c97ce8-6ac4-4712-bd34-7451c7f29249
|
3
|
|
SARS-CoV-2 viral entry and replication is impaired in Cystic Fibrosis airways due to ACE2 downregulation, file 02ef7c47-1093-4ba0-99e3-ee23e491ec74
|
3
|
|
Tuning the Loading and Release Properties of MicroRNA-Silencing Porous Silicon Nanoparticles by Using Chemically Diverse Peptide Nucleic Acid Payloads, file 214b687f-7f3a-477f-9848-3c61964a5d1e
|
3
|
|
Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene, file 8b6dc6e4-bebc-4596-a271-a6d65e422481
|
3
|
|
Effects of Sirolimus treatment on patients with β-Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4+ and CD8+ T cells, file ab9b77dc-0e9f-4ab9-996b-d44a9b7980ab
|
3
|
|
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222, file e309ade0-a9e5-3969-e053-3a05fe0a2c94
|
3
|
|
Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance, file e309ade0-d39c-3969-e053-3a05fe0a2c94
|
3
|
|
null, file e309ade0-de33-3969-e053-3a05fe0a2c94
|
3
|
|
Regulation of IL-8 gene expression in gliomas by microRNAs, file e309ade0-e2eb-3969-e053-3a05fe0a2c94
|
3
|
|
Sirolimus-mediated induction of fetal hemoglobin in beta-thalassemia: impact of the XmnI rs74482144 polymophism, file e309ade2-93b8-3969-e053-3a05fe0a2c94
|
3
|
|
Delivery of Peptide Nucleic Acids Using an Argininocalix[4]arene as Vector, file e309ade3-44f0-3969-e053-3a05fe0a2c94
|
3
|
|
New Synthetic Isoxazole Derivatives Acting as Potent Inducers of Fetal Hemoglobin in Erythroid Precursor Cells Isolated from β-Thalassemic Patients, file 301bf090-377c-4930-b40e-48a2286693a6
|
2
|
|
Decrease in α-Globin and Increase in the Autophagy-Activating Kinase ULK1 mRNA in Erythroid Precursors from β-Thalassemia Patients Treated with Sirolimus, file 42f04943-4917-465d-8a7a-c02d795af94c
|
2
|
|
Effects of Sulforaphane on SARS‑CoV‑2 infection and NF‑κB dependent expression of genes involved in the COVID‑19 'cytokine storm', file 68820a55-837d-4fa4-9587-72c71bb08926
|
2
|
|
The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers, file 7068a5bc-c5f6-4b8f-a90d-1f6890160ff6
|
2
|
|
Digital microfluidic devices for isothermal circular strand displacement polymerization of microRNAs, file e309ade0-e426-3969-e053-3a05fe0a2c94
|
2
|
|
Development of microRNA based protocols for detection of autologous blood transfusion in sport, file e309ade2-2388-3969-e053-3a05fe0a2c94
|
2
|
|
Spermine metabolite, hydrogen peroxide and aldehyde, induce the apoptosis of neuroblastoma cells associated with increase of p53, Caspase-3 and miR-34a, file e309ade2-93bd-3969-e053-3a05fe0a2c94
|
2
|
| Totale |
4.481 |