| Nome |
# |
|
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B, file e309ade5-6bd5-3969-e053-3a05fe0a2c94
|
1.134
|
|
Inhibition of autophagy reduces cell proliferation and migration by P53 restoring in ccRCC cells, file e309ade4-8670-3969-e053-3a05fe0a2c94
|
1.098
|
|
Transglutaminase-2 inhibition restores P53 expression preventing its degradation by autophagic pathway in ccRCC cells, file e309ade4-d9de-3969-e053-3a05fe0a2c94
|
1.066
|
|
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition), file e309ade4-18c8-3969-e053-3a05fe0a2c94
|
1.021
|
|
Germline BAP1 mutations induce a Warburg effect, file e309ade1-a534-3969-e053-3a05fe0a2c94
|
893
|
|
Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death, file e309ade4-6510-3969-e053-3a05fe0a2c94
|
729
|
|
The machineries, regulation and cellular functions of mitochondrial calcium, file e309ade4-3133-3969-e053-3a05fe0a2c94
|
426
|
|
Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective, file e309ade2-5c1f-3969-e053-3a05fe0a2c94
|
331
|
|
Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis, file e309ade0-f854-3969-e053-3a05fe0a2c94
|
298
|
|
Regulation of calcium fluxes by GPX8, a type-II transmembrane peroxidase enriched at the mitochondria-associated endoplasmic reticulum membrane, file e309ade4-2345-3969-e053-3a05fe0a2c94
|
210
|
|
MicroRNA501-5p induces p53 proteasome degradation through the activation of the mTOR/MDM2 pathway in ADPKD cells, file e309ade1-971c-3969-e053-3a05fe0a2c94
|
198
|
|
The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein, file e309ade4-390d-3969-e053-3a05fe0a2c94
|
183
|
|
Mitochondrial calcium homeostasis as potential target for mitochondrial medicine, file e309ade1-dee4-3969-e053-3a05fe0a2c94
|
168
|
|
Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury, file e309ade4-0984-3969-e053-3a05fe0a2c94
|
161
|
|
Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications, file e309ade4-5609-3969-e053-3a05fe0a2c94
|
158
|
|
Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75, file e309ade2-1a41-3969-e053-3a05fe0a2c94
|
148
|
|
Calcium regulates cell death in cancer: Roles of the mitochondria and mitochondria-associated membranes (MAMs), file e309ade4-7ab4-3969-e053-3a05fe0a2c94
|
137
|
|
Calcium Dynamics as a Machine for Decoding Signals, file e309ade4-4daf-3969-e053-3a05fe0a2c94
|
133
|
|
Mitochondria as the decision makers for cancer cell fate: from signaling pathways to therapeutic strategies, file d42d5ee3-f24c-48b3-b8a7-b582bc05527c
|
130
|
|
Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies, file e309ade5-2f84-3969-e053-3a05fe0a2c94
|
129
|
|
Syndromic parkinsonism and dementia associated with OPA1 missense mutations, file e309ade0-9d45-3969-e053-3a05fe0a2c94
|
123
|
|
Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma, file e309ade3-f604-3969-e053-3a05fe0a2c94
|
111
|
|
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction, file e309ade3-fc29-3969-e053-3a05fe0a2c94
|
107
|
|
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth, file e309ade2-5393-3969-e053-3a05fe0a2c94
|
97
|
|
The mystery of mitochondria-ER contact sites in physiology and pathology: A cancer perspective, file e309ade2-b2e2-3969-e053-3a05fe0a2c94
|
94
|
|
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition, file e309ade4-0fbd-3969-e053-3a05fe0a2c94
|
92
|
|
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition), file e309ade0-aa57-3969-e053-3a05fe0a2c94
|
90
|
|
Mitochondrial Stress Responses and "Mito-Inflammation" in Cystic Fibrosis, file e309ade2-d2e2-3969-e053-3a05fe0a2c94
|
90
|
|
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018, file e309ade3-c1ae-3969-e053-3a05fe0a2c94
|
89
|
|
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2, file e309ade0-a21b-3969-e053-3a05fe0a2c94
|
87
|
|
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death, file e309ade0-9dd9-3969-e053-3a05fe0a2c94
|
86
|
|
PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia, file e309ade4-c82e-3969-e053-3a05fe0a2c94
|
85
|
|
ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca2+ signaling, file e309ade1-3b76-3969-e053-3a05fe0a2c94
|
84
|
|
KRIT1 deficiency promotes aortic endothelial dysfunction, file e309ade2-a6e3-3969-e053-3a05fe0a2c94
|
84
|
|
TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry, file e309ade1-34f3-3969-e053-3a05fe0a2c94
|
82
|
|
Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane, file e309ade2-5f3c-3969-e053-3a05fe0a2c94
|
82
|
|
Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies, file e309ade1-6b6d-3969-e053-3a05fe0a2c94
|
81
|
|
Mitochondria in non-alcoholic fatty liver disease, file e309ade1-a912-3969-e053-3a05fe0a2c94
|
81
|
|
Physiopathology of the permeability transition pore: Molecular mechanisms in human pathology, file e309ade3-1be0-3969-e053-3a05fe0a2c94
|
81
|
|
BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos, file e309ade5-8618-3969-e053-3a05fe0a2c94
|
78
|
|
Mitophagy in Cardiovascular Diseases, file e309ade2-a9fd-3969-e053-3a05fe0a2c94
|
73
|
|
The dichotomous role of inflammation in the CNS: A mitochondrial point of view, file e309ade3-1b66-3969-e053-3a05fe0a2c94
|
73
|
|
SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity, file e309ade0-9e3b-3969-e053-3a05fe0a2c94
|
72
|
|
MitopatHs: a new logically-framed tool for visualizing multiple mitochondrial pathways, file e309ade4-4df2-3969-e053-3a05fe0a2c94
|
70
|
|
Translational readthrough of GLA nonsense mutations suggests dominant-negative effects exerted by the interaction of wild-type and missense variants, file e309ade4-8f47-3969-e053-3a05fe0a2c94
|
70
|
|
Defective autophagy is a key feature of cerebral cavernous malformations, file e309ade0-9d24-3969-e053-3a05fe0a2c94
|
68
|
|
A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction, file e309ade2-c4e7-3969-e053-3a05fe0a2c94
|
66
|
|
Study of PTEN subcellular localization, file e309ade0-95e7-3969-e053-3a05fe0a2c94
|
63
|
|
Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C-ring conformation, file e309ade3-4fb5-3969-e053-3a05fe0a2c94
|
63
|
|
Aortic valve stenosis and mitochondrial dysfunctions: Clinical and molecular perspectives, file e309ade3-1f5d-3969-e053-3a05fe0a2c94
|
62
|
|
p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner, file e309ade0-9c95-3969-e053-3a05fe0a2c94
|
61
|
|
Novel insights into the mitochondrial permeability transition, file e309ade0-9d8d-3969-e053-3a05fe0a2c94
|
61
|
|
Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients, file e309ade2-3efa-3969-e053-3a05fe0a2c94
|
61
|
|
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015, file e309ade0-9866-3969-e053-3a05fe0a2c94
|
60
|
|
A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss, file e309ade2-0f37-3969-e053-3a05fe0a2c94
|
60
|
|
Vav1 is necessary for PU.1 mediated upmodulation of miR-29b in acute myeloid leukaemia-derived cells, file e309ade2-dda3-3969-e053-3a05fe0a2c94
|
59
|
|
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation, file e309ade3-1d7c-3969-e053-3a05fe0a2c94
|
59
|
|
Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2, file e309ade3-5252-3969-e053-3a05fe0a2c94
|
59
|
|
STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses, file e309ade3-cce7-3969-e053-3a05fe0a2c94
|
59
|
|
Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma, file e309ade3-dfaf-3969-e053-3a05fe0a2c94
|
59
|
|
PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development, file e309ade0-eca2-3969-e053-3a05fe0a2c94
|
58
|
|
Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care, file e309ade2-9fac-3969-e053-3a05fe0a2c94
|
58
|
|
Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling, file e309ade0-95ed-3969-e053-3a05fe0a2c94
|
57
|
|
The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): Study protocol for a randomized controlled trial, file e309ade1-3dd8-3969-e053-3a05fe0a2c94
|
57
|
|
Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death, file e309ade4-2c53-3969-e053-3a05fe0a2c94
|
57
|
|
Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis, file e309ade0-95f1-3969-e053-3a05fe0a2c94
|
56
|
|
Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer's disease and mild cognitive impairment, file e309ade2-6e4f-3969-e053-3a05fe0a2c94
|
56
|
|
Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7, file e309ade0-9e31-3969-e053-3a05fe0a2c94
|
55
|
|
Mitochondria-associated membranes (MAMs) and pathologies editorial, file e309ade1-d88b-3969-e053-3a05fe0a2c94
|
55
|
|
IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice, file e309ade2-1a39-3969-e053-3a05fe0a2c94
|
55
|
|
NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus, file e309ade2-1a3f-3969-e053-3a05fe0a2c94
|
55
|
|
Cancer metabolism and mitochondria: Finding novel mechanisms to fight tumours, file e309ade2-d4c6-3969-e053-3a05fe0a2c94
|
55
|
|
The versatility of mitochondrial calcium signals: from stimulation of cell metabolism to induction of cell death, file e309ade4-d370-3969-e053-3a05fe0a2c94
|
55
|
|
Characterization of Dermal Stem Cells of Diabetic Patients, file e309ade2-d50e-3969-e053-3a05fe0a2c94
|
54
|
|
Metformin Induces Apoptosis and Inhibits Notch1 in Malignant Pleural Mesothelioma Cells, file e309ade3-a7a9-3969-e053-3a05fe0a2c94
|
54
|
|
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition), file e309ade3-d6e1-3969-e053-3a05fe0a2c94
|
54
|
|
Emerging molecular mechanisms in chemotherapy: Ca2+signaling at the mitochondria-associated endoplasmic reticulum membranes, file e309ade4-88d2-3969-e053-3a05fe0a2c94
|
54
|
|
Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/mTOR signaling, file e309ade1-9802-3969-e053-3a05fe0a2c94
|
52
|
|
Mitochondrial calcium uniporter complex modulation in cancerogenesis, file e309ade2-9fae-3969-e053-3a05fe0a2c94
|
52
|
|
Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+, file e309ade0-9665-3969-e053-3a05fe0a2c94
|
51
|
|
Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings, file e309ade1-cb76-3969-e053-3a05fe0a2c94
|
51
|
|
Osteogenic differentiation of human MSCs: Specific occupancy of the mitochondrial DNA by NFATc1 transcription factor, file e309ade4-6435-3969-e053-3a05fe0a2c94
|
50
|
|
Inside the tumor: p53 modulates calcium homeostasis, file e309ade0-95f2-3969-e053-3a05fe0a2c94
|
49
|
|
Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis, file e309ade2-aa02-3969-e053-3a05fe0a2c94
|
46
|
|
Targeting the nlrp3 inflammasome as a new therapeutic option for overcoming cancer, file e309ade4-b791-3969-e053-3a05fe0a2c94
|
46
|
|
Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases, file e309ade5-7695-3969-e053-3a05fe0a2c94
|
46
|
|
PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2, file e309ade1-a5e4-3969-e053-3a05fe0a2c94
|
45
|
|
Deficiency of mitochondrial aspartate-glutamate carrier 1 leads to oligodendrocyte precursor cell proliferation defects both in vitro and in vivo, file e309ade2-9fb6-3969-e053-3a05fe0a2c94
|
45
|
|
Autophagy and mitophagy elements are increased in body fluids of multiple sclerosis-affected individuals, file e309ade4-1204-3969-e053-3a05fe0a2c94
|
45
|
|
Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease, file e309ade1-a23e-3969-e053-3a05fe0a2c94
|
44
|
|
Fluorescent Light Energy (FLE) Acts on Mitochondrial Physiology Improving Wound Healing, file e309ade4-6c53-3969-e053-3a05fe0a2c94
|
44
|
|
P3.03-22 IL-1β as a New Early Predictive Biomarker for Non-Small Cell Lung Cancers Outcome, file e309ade4-ac87-3969-e053-3a05fe0a2c94
|
44
|
|
Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis, file e309ade2-d08c-3969-e053-3a05fe0a2c94
|
43
|
|
The Tricky Connection between Extracellular Vesicles and Mitochondria in Inflammatory-Related Diseases, file 859f3aca-f569-41cc-a199-0125984702ed
|
42
|
|
Mitochondrial DNA keeps you young, file e309ade2-13d2-3969-e053-3a05fe0a2c94
|
41
|
|
Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes, file e309ade1-34ec-3969-e053-3a05fe0a2c94
|
40
|
|
LonP1 differently modulates mitochondrial function and bioenergetics of primary versus metastatic colon cancer cells, file e309ade2-19da-3969-e053-3a05fe0a2c94
|
40
|
|
Citrate Mediates Crosstalk between Mitochondria and the Nucleus to Promote Human Mesenchymal Stem Cell In Vitro Osteogenesis, file e309ade2-a9ff-3969-e053-3a05fe0a2c94
|
40
|
|
Hyaluronic Acid Induces Activation of the kappa-Opioid Receptor, file e309ade4-7940-3969-e053-3a05fe0a2c94
|
40
|
|
Pioglitazone improves mitochondrial organization and bioenergetics in down syndrome cells, file e309ade2-9fb0-3969-e053-3a05fe0a2c94
|
39
|
| Totale |
13.813 |