| Nome |
# |
|
Targeting the phosphatidylinositol 3-kinase/Akt/mechanistic target of rapamycin signaling pathway in B-lineage acute lymphoblastic leukemia: An update, file e309ade2-aa7d-3969-e053-3a05fe0a2c94
|
292
|
|
Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model, file e309ade2-accb-3969-e053-3a05fe0a2c94
|
239
|
|
Role of physical exercise in the regulation of epigenetic mechanisms in inflammation, cancer, neurodegenerative diseases, and aging process, file e309ade3-d642-3969-e053-3a05fe0a2c94
|
178
|
|
COVID-19 and individual genetic susceptibility/receptivity: Role of ACE1/ACE2 genes, immunity, inflammation and coagulation. might the double x-chromosome in females be protective against SARS-COV-2 compared to the single x-chromosome in males?, file e309ade2-9f99-3969-e053-3a05fe0a2c94
|
132
|
|
Targeting mTOR in Acute Lymphoblastic Leukemia, file e309ade2-1213-3969-e053-3a05fe0a2c94
|
111
|
|
PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell lines, file e309ade1-50ca-3969-e053-3a05fe0a2c94
|
96
|
|
Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and aging, file e309ade1-c3a8-3969-e053-3a05fe0a2c94
|
94
|
|
Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease, file e309ade1-f123-3969-e053-3a05fe0a2c94
|
93
|
|
Cardiovascular disease-related miRNAs expression: Potential role as biomarkers and effects of training exercise, file e309ade1-c7b1-3969-e053-3a05fe0a2c94
|
91
|
|
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts, file e309ade2-10ab-3969-e053-3a05fe0a2c94
|
89
|
|
Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in Cognitive Impairment Diseases, file e309ade1-b234-3969-e053-3a05fe0a2c94
|
79
|
|
Actively targeted nanocarriers for drug delivery to cancer cells, file e309ade3-e106-3969-e053-3a05fe0a2c94
|
78
|
|
MDM2/X inhibitors under clinical evaluation: Perspectives for the management of hematological malignancies and pediatric cancer, file e309ade1-74a7-3969-e053-3a05fe0a2c94
|
75
|
|
The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells, file e309ade0-825e-3969-e053-3a05fe0a2c94
|
73
|
|
Heterogeneity of mesenchymal stromal cells in lymphoproliferative disorders, file e309ade0-eef9-3969-e053-3a05fe0a2c94
|
73
|
|
Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1, file e309ade0-f319-3969-e053-3a05fe0a2c94
|
73
|
|
Impact of physical exercise in cancer survivors during and after antineoplastic treatments, file e309ade1-b725-3969-e053-3a05fe0a2c94
|
69
|
|
TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress, file e309ade1-f11f-3969-e053-3a05fe0a2c94
|
69
|
|
Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity, file e309ade2-e1dc-3969-e053-3a05fe0a2c94
|
68
|
|
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women, file e309ade1-8473-3969-e053-3a05fe0a2c94
|
66
|
|
Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214-ABL1 fusion protein in human Acute Lymphoblastic Leukemia, file e309ade1-c418-3969-e053-3a05fe0a2c94
|
66
|
|
Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia, file e309ade0-8149-3969-e053-3a05fe0a2c94
|
64
|
|
The gamma-secretase inhibitors enhance the anti-leukemic activity of ibrutinib in B-CLL cells, file e309ade1-9c8e-3969-e053-3a05fe0a2c94
|
64
|
|
The Sorafenib plus Nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of the FLT3 and p53 status, file e309ade0-b7c3-3969-e053-3a05fe0a2c94
|
62
|
|
Healthy CD4+ T lymphocytes are not affected by targeted therapies against the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia, file e309ade1-c41a-3969-e053-3a05fe0a2c94
|
62
|
|
Effects of hypoxia and bed rest on markers of cardiometabolic risk: Compensatory changes in circulating trail and glutathione redox capacity, file e309ade1-e83f-3969-e053-3a05fe0a2c94
|
62
|
|
Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia, file e309ade0-fb3b-3969-e053-3a05fe0a2c94
|
61
|
|
Roles and clinical implications of microRNAs in acute lymphoblastic leukemia, file e309ade3-b28c-3969-e053-3a05fe0a2c94
|
61
|
|
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3, file e309ade0-a4fb-3969-e053-3a05fe0a2c94
|
60
|
|
Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model, file e309ade0-f541-3969-e053-3a05fe0a2c94
|
60
|
|
Circulating levels of TNF-related apoptosis inducing-ligand are decreased in patients with large adult-type granulosa cell tumors—implications for therapeutic potential, file e309ade2-e285-3969-e053-3a05fe0a2c94
|
60
|
|
Clinical perspectives of TRAIL: Insights into central nervous system disorders, file e309ade0-d002-3969-e053-3a05fe0a2c94
|
59
|
|
Physical training interventions for children and teenagers affected by acute lymphoblastic leukemia and related treatment impairments, file e309ade1-c529-3969-e053-3a05fe0a2c94
|
58
|
|
Maternal Haplotypes in DHFR Promoter and MTHFR Gene in Tuning Childhood Acute Lymphoblastic Leukemia Onset-Latency: Genetic/Epigenetic Mother/Child Dyad Study (GEMCDS), file e309ade2-4d01-3969-e053-3a05fe0a2c94
|
57
|
|
The anti-leukemic activity of sodium dichloroacetate in p53(mutated/null) cells is mediated by a p53-independent ILF3/p21 pathway, file e309ade2-e097-3969-e053-3a05fe0a2c94
|
57
|
|
Influence of physical exercise on microRNAs in skeletal muscle regeneration, aging and diseases, file e309ade1-c692-3969-e053-3a05fe0a2c94
|
55
|
|
Soluble TRAIL is elevated in recurrent miscarriage and inhibits the in vitro adhesion and migration of HTR8 trophoblastic cells, file e309ade0-f277-3969-e053-3a05fe0a2c94
|
53
|
|
TRAIL, OPG, and TWEAK in kidney disease: biomarkers or therapeutic targets?, file e309ade2-3781-3969-e053-3a05fe0a2c94
|
52
|
|
SARS-CoV-2 nucleocapsid-protein and ultrastructural modifications in small bowel of a four week negative COVID-19 patient, file e309ade4-c9cd-3969-e053-3a05fe0a2c94
|
48
|
|
Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment, file e309ade0-f462-3969-e053-3a05fe0a2c94
|
47
|
|
Applications of nanoparticles in cancer medicine and beyond: optical and multimodal in vivo imaging, tissue targeting and drug delivery, file e309ade3-ffbf-3969-e053-3a05fe0a2c94
|
46
|
|
Overcoming of Microenvironment Protection on Primary Chronic Lymphocytic Leukemia Cells after Treatment with BTK and MDM2 Pharmacological Inhibitors, file e309ade5-1e4d-3969-e053-3a05fe0a2c94
|
45
|
|
The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias, file e309ade4-cc42-3969-e053-3a05fe0a2c94
|
44
|
|
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity, file e309ade3-b28b-3969-e053-3a05fe0a2c94
|
41
|
|
GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients, file e309ade4-ed69-3969-e053-3a05fe0a2c94
|
40
|
|
Accuracy of intraocular lens power calculation for cataract surgery after deep anterior lamellar keratoplasty, file 43255b2d-990a-4347-b25c-b8b7a3679987
|
37
|
|
Association between thyroid hormones and TRAIL, file e309ade1-9bec-3969-e053-3a05fe0a2c94
|
17
|
|
TNF-related apoptosis inducing ligand in ocular cancers and ocular diabetic complications, file e309ade0-7ae9-3969-e053-3a05fe0a2c94
|
16
|
|
Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment, file e309ade2-cd1c-3969-e053-3a05fe0a2c94
|
16
|
|
The combination of N-acetyl cysteine, alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of endometriosis, file e309ade0-9d58-3969-e053-3a05fe0a2c94
|
11
|
|
Autoinflammatory diseases and cytokine storms-imbalances of innate and adaptative immunity, file e309ade5-1c1d-3969-e053-3a05fe0a2c94
|
11
|
|
Sex/gender‐specific imbalance in CVD: Could physical activity help to improve clinical outcome targeting CVD molecular mechanisms in women?, file e73cbefd-b699-4a11-a8a0-eeac008118dd
|
11
|
|
Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy, file e309ade0-9600-3969-e053-3a05fe0a2c94
|
10
|
|
PI3K/Akt/mTOR Pathway in Acute Lymphoblastic Leukemia Targeted Therapies, file e309ade2-6232-3969-e053-3a05fe0a2c94
|
10
|
|
Natural Killer Cells in SARS-CoV-2-Vaccinated Subjects with Increased Effector Cytotoxic CD56dim Cells and Memory-Like CD57+NKG2C+CD56dim Cells, file 7c317427-b717-4f34-b14a-8d843e870aaa
|
9
|
|
PI3K/Akt/mTOR Pathway in Acute Lymphoblastic Leukemia Targeted Therapies, file e309ade4-ea64-3969-e053-3a05fe0a2c94
|
9
|
|
p53/NF-kB Balance in SARS-CoV-2 Infection: From OMICs, Genomics and Pharmacogenomics Insights to Tailored Therapeutic Perspectives (COVIDomics), file 31c7762d-9d8c-4b3a-84e0-86caa2750b25
|
8
|
|
Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells, file 4ce2e0f6-89bc-43ae-8b4c-f623d18b86ee
|
8
|
|
TRAIL Modulates the Immune System and Protects against the Development of Diabetes, file e309ade0-7ada-3969-e053-3a05fe0a2c94
|
8
|
|
Rationale for Considering Oral Idasanutlin as a Therapeutic Option for COVID-19 Patients, file e309ade3-3ff9-3969-e053-3a05fe0a2c94
|
8
|
|
TRAIL reduces impaired glucose tolerance and NAFLD in the high-fat diet fed mouse, file e309ade4-f6f0-3969-e053-3a05fe0a2c94
|
8
|
|
MAM-2201 acute administration impairs motor, sensorimotor, prepulse inhibition, and memory functions in mice: a comparison with its analogue AM-2201, file 3d79e4e1-e302-4409-9559-6ae451f1e7db
|
7
|
|
Activation of the p53 pathway induces α-smooth muscle actin expression in both myeloid leukemic cells and normal macrophages, file e309ade1-c172-3969-e053-3a05fe0a2c94
|
7
|
|
Inflammation and Cardiovascular Cross Talk in Ischemic Vascular Diseases, file ba5800f7-c027-4a49-8293-3a32e4d9a2cf
|
6
|
|
Influence of the human immunodeficency virus type 1 Tat protein on the proliferation and differentiation of PC12 rat pheochromocytoma cells, file e309ade0-2141-3969-e053-3a05fe0a2c94
|
6
|
|
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity, file e309ade0-f547-3969-e053-3a05fe0a2c94
|
6
|
|
An imbalanced OPG/TRAIL ratio is associated to severe acute myocardial infarction, file e309ade2-bbb8-3969-e053-3a05fe0a2c94
|
6
|
|
Host genetics impact on SARS-CoV-2 vaccine-induced immunoglobulin levels and dynamics: The role of TP53, ABO, APOE, ACE2, HLA-A, and CRP genes, file 6ae696c2-f770-4de1-ac44-8097d683c545
|
5
|
|
Roles and clinical implications of microRNAs in acute lymphoblastic leukemia, file e309ade1-c7af-3969-e053-3a05fe0a2c94
|
5
|
|
Role of physical exercise in the regulation of epigenetic mechanisms in inflammation, cancer, neurodegenerative diseases, and aging process, file e309ade2-3597-3969-e053-3a05fe0a2c94
|
5
|
|
Lipids at the Nexus between Cerebrovascular Disease and Vascular Dementia: The Impact of HDL-Cholesterol and Ceramides, file 4bd5d48f-2700-45d5-970f-c71eddb7f82a
|
4
|
|
Different levels of the neuronal nitric oxide synthase isoform modulate the rate of osteoclastic differentiation of TIB-71 and CRL-2278 RAW 264.7 murine cell clones, file b08ada7e-43eb-4ff5-984b-25b1def71123
|
4
|
|
Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol, file e309ade0-46e5-3969-e053-3a05fe0a2c94
|
4
|
|
Dasatinib plus Nutlin-3 shows synergistic anti-leukemic activity in both p53wild-type and p53mutated B chronic lymphocytic leukemias by inhibiting the Akt pathway., file e309ade1-7de8-3969-e053-3a05fe0a2c94
|
4
|
|
Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation., file e309ade1-c461-3969-e053-3a05fe0a2c94
|
4
|
|
null, file e309ade1-c52c-3969-e053-3a05fe0a2c94
|
4
|
|
TRAIL/DR5 pathway promotes AKT phosphorylation, skeletal muscle differentiation, and glucose uptake, file e309ade5-18e1-3969-e053-3a05fe0a2c94
|
4
|
|
MDM2 inhibitors counteract inflammation by stabilization of ACE2 in vitro, file 447c39a9-8a62-46c4-a8f3-1256dcae3b57
|
3
|
|
The role of the mTOR pathway in diabetic retinopathy, file 636de3b9-048d-4992-9efa-45b1dc1200f8
|
3
|
|
null, file e309ade0-a687-3969-e053-3a05fe0a2c94
|
3
|
|
Simultaneous determination of multiple cytokines reveals a pro-inflammatory and pro-angiogenic signature after major cardiothoracic surgery: potential role of C-reactive protein, file e309ade0-f540-3969-e053-3a05fe0a2c94
|
3
|
|
Decreased levels of soluble TNF-related apoptosis-inducing ligand (TRAIL) in the conjunctival sac fluid of patients with diabetes affected by proliferative retinopathy., file e309ade1-7de1-3969-e053-3a05fe0a2c94
|
3
|
|
TRAIL reduces impaired glucose tolerance and NAFLD in the high-fat diet fed mouse, file e309ade1-9dd7-3969-e053-3a05fe0a2c94
|
3
|
|
Soluble TRAIL is present at high concentrations in seminal plasma and promotes spermatozoa survival, file e309ade1-b6c7-3969-e053-3a05fe0a2c94
|
3
|
|
Actively targeted nanocarriers for drug delivery to cancer cells, file e309ade2-2f52-3969-e053-3a05fe0a2c94
|
3
|
|
Serum TRAIL levels increase shortly after insulin therapy and metabolic stabilization in children with type 1 diabetes mellitus, file e309ade2-e14c-3969-e053-3a05fe0a2c94
|
3
|
|
Cell cycle block by p53 activation reduces SARS-CoV-2 release in A549-hAce2 cells, file f96d1ea8-8273-42f2-ac0c-8f8ca676d9bf
|
3
|
|
Sensorimotor Alterations Induced by Novel Fentanyl Analogs in Mice: Possible Impact on Human Driving Performances, file 0c5b6e8a-5417-4e5a-b022-534dd7caca0e
|
2
|
|
Impact of Topographic Hot Spots on the Refractive Outcomes of Combined DMEK and Cataract Surgery, file 43d6eb87-cf6f-4cc4-be0b-4d718a9a0452
|
2
|
|
LINE-1 global DNA methylation, iron homeostasis genes, sex and age in sudden sensorineural hearing loss (SSNHL), file 61d2abc9-6024-497b-af54-528ae69e63e5
|
2
|
|
Ethosomes nanodelivery of the MDM2 inhibitor Nutlin-3a efficiently induces cells death in melanoma, file 8b713a7b-b843-4262-a17e-f85d51ddd5da
|
2
|
|
COVID-19 Vaccination May Not Increase Rates of Corneal Graft Rejection, file 9c526833-7d3d-4c13-bbc4-780a6b01bf7d
|
2
|
|
Classical and Innovative Evidence for Therapeutic Strategies in Retinal Dysfunctions, file b66b16df-e1c7-47f2-b235-8370c5a6ae12
|
2
|
|
A role of the TRAIL-TRAIL receptor system in the pathogenesis of diabetes, file cebb3332-1dd3-4d93-8b41-6446b193866b
|
2
|
|
Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes, file e309ade0-2bcd-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade0-2f25-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade0-375c-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade0-a9cc-3969-e053-3a05fe0a2c94
|
2
|
|
Inhibitory effect of natural anti-inflammatory compounds on cytokines released by chronic venous disease patient-derived endothelial cells., file e309ade0-c53d-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade0-ecb0-3969-e053-3a05fe0a2c94
|
2
|
| Totale |
3.856 |