| Nome |
# |
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Non-invasive Prenatal Testing Using Fetal DNA, file e309ade3-bdaf-3969-e053-3a05fe0a2c94
|
718
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|
Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia, file e309ade2-4e76-3969-e053-3a05fe0a2c94
|
151
|
|
Ground state naïve pluripotent stem cells and CRISPR/Cas9 gene correction for β-thalassemia, file e309ade1-8cb9-3969-e053-3a05fe0a2c94
|
141
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|
An Aγ-globin G->A gene polymorphism associated with β(0)39 thalassemia globin gene and high fetal hemoglobin production, file e309ade1-7733-3969-e053-3a05fe0a2c94
|
140
|
|
Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions, file e309ade2-d99c-3969-e053-3a05fe0a2c94
|
123
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|
Non-invasive fetal sex diagnosis in plasma of early weeks pregnants using droplet digital PCR, file e309ade3-1dbb-3969-e053-3a05fe0a2c94
|
118
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|
BCL11A mRNA targeting by miR-210: A possible network regulating γ-globin gene expression, file e309ade1-8625-3969-e053-3a05fe0a2c94
|
111
|
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Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells, file e309ade2-4e78-3969-e053-3a05fe0a2c94
|
97
|
|
MTOR and STAT3 pathway hyper-activation is associated with elevated interleukin-6 levels in patients with shwachman-diamond syndrome: Further evidence of lymphoid lineage impairment, file e309ade2-9b09-3969-e053-3a05fe0a2c94
|
95
|
|
Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance, file e309ade3-a96d-3969-e053-3a05fe0a2c94
|
95
|
|
Postnatal and non-invasive prenatal detection of β-thalassemia mutations based on Taqman genotyping assays, file e309ade1-b707-3969-e053-3a05fe0a2c94
|
92
|
|
MicroRNAs and Long Non-coding RNAs in Genetic Diseases, file e309ade2-1ab8-3969-e053-3a05fe0a2c94
|
88
|
|
Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin, file e309ade0-a5be-3969-e053-3a05fe0a2c94
|
83
|
|
A validated cellular biobank for β-thalassemia, file e309ade0-ee58-3969-e053-3a05fe0a2c94
|
78
|
|
Differential Effects of Angelicin Analogues on NF-kB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells, file e309ade1-8832-3969-e053-3a05fe0a2c94
|
72
|
|
Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells, file e309ade0-ad71-3969-e053-3a05fe0a2c94
|
70
|
|
Regulation of IL-8 gene expression in gliomas by microRNA miR-93, file e309ade0-a781-3969-e053-3a05fe0a2c94
|
68
|
|
A peptide nucleic acid against microrna miR-145-5p enhances the expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells, file e309ade1-a84d-3969-e053-3a05fe0a2c94
|
67
|
|
Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor, file e309ade3-173a-3969-e053-3a05fe0a2c94
|
67
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|
Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA), file e309ade2-1293-3969-e053-3a05fe0a2c94
|
65
|
|
MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells, file e309ade2-d9f2-3969-e053-3a05fe0a2c94
|
61
|
|
Production of β-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous β039 thalassemia patients, file e309ade0-f426-3969-e053-3a05fe0a2c94
|
58
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|
Surface plasmon resonance analysis to detect the β+ IVSI-110 thalassemia mutation in circulating cell-free fetal DNA, file e309ade3-9e4c-3969-e053-3a05fe0a2c94
|
58
|
|
Treatment of human airway epithelial Calu-3 cells with a peptide-nucleic acid (PNA) targeting the microRNA miR-101-3p is associated with increased expression of the cystic fibrosis Transmembrane Conductance Regulator () gene, file f8818e72-4359-45e8-bda1-5ad1b8cc735f
|
58
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|
Pro‑apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro, file e309ade2-ef0e-3969-e053-3a05fe0a2c94
|
57
|
|
Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae, file e309ade0-d970-3969-e053-3a05fe0a2c94
|
56
|
|
Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites, file e309ade0-ee55-3969-e053-3a05fe0a2c94
|
56
|
|
Generation and characterization of a transgenic mouse carrying a functional human β-globin gene with the IVSI-6 thalassemia mutation, file e309ade0-a54c-3969-e053-3a05fe0a2c94
|
55
|
|
Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells, file e309ade2-d6a6-3969-e053-3a05fe0a2c94
|
54
|
|
Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line, file e309ade2-82f2-3969-e053-3a05fe0a2c94
|
46
|
|
Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis, file e309ade2-d08c-3969-e053-3a05fe0a2c94
|
43
|
|
Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters, file e309ade2-5134-3969-e053-3a05fe0a2c94
|
36
|
|
UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation, file e309ade2-1ad9-3969-e053-3a05fe0a2c94
|
35
|
|
Expression of γ-globin genes in β-thalassemia patients treated with sirolimus: results from a pilot clinical trial (Sirthalaclin), file 330010a8-57ab-464b-ac76-8393bc420f74
|
29
|
|
Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis, file e309ade4-9951-3969-e053-3a05fe0a2c94
|
25
|
|
A PNA-based masking strategy for CFTR upregulation by targeting miR-145-5p binding sites of CFTR mRNA, file e309ade4-e1d6-3969-e053-3a05fe0a2c94
|
24
|
|
Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein, file e309ade4-a21c-3969-e053-3a05fe0a2c94
|
23
|
|
A peptide nucleic acid (PNA) masking the miR-145-5p binding site of the 3’UTR of the cystic fibrosis transmembrane conductance regulator (CFTR) mRNA enhances CFTR expression in Calu-3 cells, file e309ade5-219c-3969-e053-3a05fe0a2c94
|
20
|
|
Evaluation of S-RBD and high specificity ACE-2-binding antibodies on SARS-CoV-2 patients after six months from infection, file f3e0af1d-da6e-4707-ba0a-979914c8fcd6
|
17
|
|
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening, file e309ade2-d995-3969-e053-3a05fe0a2c94
|
16
|
|
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222, file e309ade3-1797-3969-e053-3a05fe0a2c94
|
16
|
|
Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation., file e309ade0-b02c-3969-e053-3a05fe0a2c94
|
15
|
|
Therapy for Cystic Fibrosis Caused by Nonsense Mutations, file e309ade0-e68c-3969-e053-3a05fe0a2c94
|
12
|
|
A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1, file e309ade4-d2e9-3969-e053-3a05fe0a2c94
|
11
|
|
Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines, file e309ade0-301b-3969-e053-3a05fe0a2c94
|
10
|
|
Trans-Resveratrol in nutraceuticals: issuses in retail quality and effectiveness, file e309ade0-3833-3969-e053-3a05fe0a2c94
|
10
|
|
Programmable interactions of functionalized single bioparticles in a dielectrophoresis-based microarray chip., file e309ade0-4946-3969-e053-3a05fe0a2c94
|
10
|
|
Up-regulation of miR-34a-3p and miR-744-3p is associated with down-regulation of PTEN in lymphoblastoid cells from Shwachman-Diamond Syndrome patients, file e309ade4-d87f-3969-e053-3a05fe0a2c94
|
10
|
|
Treatment of erythroid precursor cells from β‐thalassemia patients with cinchona alkaloids: Induction of fetal hemoglobin production, file e309ade5-17a9-3969-e053-3a05fe0a2c94
|
9
|
|
Droplet Digital PCR for Non-Invasive Prenatal Detection of Fetal Single-Gene Point Mutations in Maternal Plasma, file e309ade5-6a1a-3969-e053-3a05fe0a2c94
|
9
|
|
New TMA (4,6,4'-Trimethyl angelicin) Analogues as Anti-Inflammatory Agents in the Treatment of Cystic Fibrosis Lung Disease, file 2a875cf3-4552-447b-9ec1-76c7b553d7cc
|
8
|
|
Screening Readthrough Compounds to Suppress Nonsense Mutations: Possible Application to β-Thalassemia, file e309ade2-aa0e-3969-e053-3a05fe0a2c94
|
8
|
|
A peptide nucleic acid targeting the acpP gene of Pseudomonas aeruginosa inhibits bacterial induced biological alterations in cystic fibrosis cells, file e309ade5-11c3-3969-e053-3a05fe0a2c94
|
8
|
|
Phenyl-substituted aminomethylene-bisphosphonates inhibit human P5C reductase and show antiproliferative activity against proline-hyperproducing tumour cells, file e309ade5-29d2-3969-e053-3a05fe0a2c94
|
8
|
|
In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity, file e309ade5-310c-3969-e053-3a05fe0a2c94
|
8
|
|
A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs, file 8580432b-00cf-4c35-9b4d-8db5dc11d407
|
7
|
|
Sirolimus-mediated induction of fetal hemoglobin in beta-thalassemia: impact of the XmnI rs74482144 polymophism, file e309ade5-1100-3969-e053-3a05fe0a2c94
|
7
|
|
In vitro induction of interleukin-8 by SARS-CoV-2 Spike protein is inhibited in bronchial epithelial IB3-1 cells by a miR-93-5p agomiR, file e309ade5-1660-3969-e053-3a05fe0a2c94
|
7
|
|
Non-invasive prenatal detection of beta-thalassemia mutations in maternal plasma using Droplet Digital PCR, file e309ade4-f3ab-3969-e053-3a05fe0a2c94
|
6
|
|
Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β(0)-Thalassemia Families with High Fetal Hemoglobin Levels, file e309ade0-e064-3969-e053-3a05fe0a2c94
|
5
|
|
Surface plasmon resonance analysis to detect the β+ IVSI-110 thalassemia mutation in circulating cell-free fetal DNA, file e309ade0-e0cb-3969-e053-3a05fe0a2c94
|
5
|
|
Inhibition by Thyroid Hormones of Cell Migration Activated by IGF-1 and MCP-1 in THP-1 Monocytes: Focus on Signal Transduction Events Proximal to Integrin αvβ3, file e309ade5-7fb5-3969-e053-3a05fe0a2c94
|
5
|
|
A Signature of Differentially Expressed Micrornas in Lymphoblastoid Cells from Shwachman-Diamond Syndrome Patients Indicates Possible Molecular Targets for Mirna Therapeutics, file e309ade5-9f9d-3969-e053-3a05fe0a2c94
|
5
|
|
Nanoparticle-Enhanced Surface Plasmon Resonance Imaging Enables the Ultrasensitive Detection of Non-Amplified Cell-Free Fetal DNA for Non-Invasive Prenatal Testing, file e309ade5-a108-3969-e053-3a05fe0a2c94
|
5
|
|
A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs, file 25107cdf-6b9d-4a32-ad7a-0f7171474ccf
|
4
|
|
A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs, file 620f0aa5-0d1b-45ad-b2db-b53c8ca50249
|
4
|
|
509 Cystic fibrosis transmembrane conductance regulator positively regulates angiotensin-converting enzyme 2 expression and SARS-CoV-2 viral entry into airway epithelial cells: Implications for patients with cystic fibrosis, file af773ed6-8a3c-4d7a-b2d7-e099c479d507
|
4
|
|
Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor, file e309ade0-28aa-3969-e053-3a05fe0a2c94
|
4
|
|
Up-regulation of miR-34a-3p and miR-744-3p is associated with down-regulation of PTEN in lymphoblastoid cells from Shwachman-Diamond Syndrome patients, file e309ade2-9626-3969-e053-3a05fe0a2c94
|
4
|
|
Possible effects of sirolimus treatment on the long‑term efficacy of COVID‑19 vaccination in patients with β‑thalassemia: A theoretical perspective, file e309ade5-5a7d-3969-e053-3a05fe0a2c94
|
4
|
|
Effects of Sirolimus treatment on patients with β-Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4+ and CD8+ T cells, file 01c97ce8-6ac4-4712-bd34-7451c7f29249
|
3
|
|
SARS-CoV-2 viral entry and replication is impaired in Cystic Fibrosis airways due to ACE2 downregulation, file 02ef7c47-1093-4ba0-99e3-ee23e491ec74
|
3
|
|
Effects of Sirolimus treatment on patients with β-Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4+ and CD8+ T cells, file ab9b77dc-0e9f-4ab9-996b-d44a9b7980ab
|
3
|
|
null, file e309ade0-22d5-3969-e053-3a05fe0a2c94
|
3
|
|
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222, file e309ade0-a9e5-3969-e053-3a05fe0a2c94
|
3
|
|
Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance, file e309ade0-d39c-3969-e053-3a05fe0a2c94
|
3
|
|
Regulation of IL-8 gene expression in gliomas by microRNAs, file e309ade0-e2eb-3969-e053-3a05fe0a2c94
|
3
|
|
Non-invasive prenatal detection of beta-thalassemia mutations in maternal plasma using Droplet Digital PCR, file e309ade2-9365-3969-e053-3a05fe0a2c94
|
3
|
|
Sirolimus-mediated induction of fetal hemoglobin in beta-thalassemia: impact of the XmnI rs74482144 polymophism, file e309ade2-93b8-3969-e053-3a05fe0a2c94
|
3
|
|
Overview of CF lung pathophysiology, file 553c422f-1f0a-4907-9c06-26cd4039f241
|
2
|
|
The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers, file 7068a5bc-c5f6-4b8f-a90d-1f6890160ff6
|
2
|
|
null, file e309ade0-a50b-3969-e053-3a05fe0a2c94
|
2
|
|
Digital microfluidic devices for isothermal circular strand displacement polymerization of microRNAs, file e309ade0-e426-3969-e053-3a05fe0a2c94
|
2
|
|
Expression of Pro-inflammatory Interleukin-8 is Reduced by Ayurvedic Decoctions, file e309ade1-c3ae-3969-e053-3a05fe0a2c94
|
2
|
|
Development of microRNA based protocols for detection of autologous blood transfusion in sport, file e309ade2-2388-3969-e053-3a05fe0a2c94
|
2
|
|
Peptide Nucleic Acids for MicroRNA Targeting, file e309ade4-85e6-3969-e053-3a05fe0a2c94
|
2
|
|
null, file 683c2234-4793-4b0a-9ccf-72e9fd6e3fb3
|
1
|
|
Involvement of miRNA in erythroid differentiation, file 7313076f-74f0-4775-9e6a-7d32a5efc0cc
|
1
|
|
Bergamot (Citrus bergamia Risso) fruit extracts as gamma-globin gene expression inducers: Phyto-chemical and functional perspectives, file e309ade0-28fa-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-e2f0-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-e32f-3969-e053-3a05fe0a2c94
|
1
|
|
High levels of apoptosis induced in human glioma cell lines by combined treatment with antagomiR PNAs and pre-miRNA molecules, file e309ade0-e727-3969-e053-3a05fe0a2c94
|
1
|
|
Induction of apoptosis of human glioma cell lines: Effects of combined treatment with corilagin and temozolomide, file e309ade0-e728-3969-e053-3a05fe0a2c94
|
1
|
|
A Novel Frameshift Mutation (+A) at Codon 18 of the beta-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and deltabeta-Thalassemia, file e309ade0-e965-3969-e053-3a05fe0a2c94
|
1
|
|
Everolimus is a potent inducer of erythroid differentation and gamma-globin gene expression in human erythroid cells, file e309ade0-e9c8-3969-e053-3a05fe0a2c94
|
1
|
|
Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs, file e309ade0-eac2-3969-e053-3a05fe0a2c94
|
1
|
|
Expression of miR-93 and IL-8 During Pseudomonas aeruginosa Mediated Induction of Pro-Inflammatory Responses, file e309ade0-eac4-3969-e053-3a05fe0a2c94
|
1
|
|
The biocompatibility of materials used in printed circuit board technologies with respect to primary neuronal and K562 cells, file e309ade0-eb21-3969-e053-3a05fe0a2c94
|
1
|
|
Virtual screening against nuclear factor kB (NF-kB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis, file e309ade0-eb28-3969-e053-3a05fe0a2c94
|
1
|
|
Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives, file e309ade0-eb2e-3969-e053-3a05fe0a2c94
|
1
|
| Totale |
3.649 |