| Nome |
# |
|
Targeting the phosphatidylinositol 3-kinase/Akt/mechanistic target of rapamycin signaling pathway in B-lineage acute lymphoblastic leukemia: An update, file e309ade2-aa7d-3969-e053-3a05fe0a2c94
|
296
|
|
Ectopic expression of PLC-β2 in non-invasive breast tumor cells plays a protective role against malignant progression and is correlated with the deregulation of miR-146a, file e309ade2-1fe0-3969-e053-3a05fe0a2c94
|
113
|
|
PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell lines, file e309ade1-50ca-3969-e053-3a05fe0a2c94
|
102
|
|
Cardiovascular disease-related miRNAs expression: Potential role as biomarkers and effects of training exercise, file e309ade1-c7b1-3969-e053-3a05fe0a2c94
|
94
|
|
CD133 in Breast Cancer Cells: More than a Stem Cell Marker, file e309ade2-7d0d-3969-e053-3a05fe0a2c94
|
90
|
|
Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells, file e309ade2-d6c8-3969-e053-3a05fe0a2c94
|
75
|
|
The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells, file e309ade0-825e-3969-e053-3a05fe0a2c94
|
73
|
|
Impact of physical exercise in cancer survivors during and after antineoplastic treatments, file e309ade1-b725-3969-e053-3a05fe0a2c94
|
69
|
|
Vav1 downmodulates Akt in different breast cancer subtypes: A new promising chance to improve breast cancer outcome, file e309ade1-e585-3969-e053-3a05fe0a2c94
|
68
|
|
Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214-ABL1 fusion protein in human Acute Lymphoblastic Leukemia, file e309ade1-c418-3969-e053-3a05fe0a2c94
|
66
|
|
Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia, file e309ade0-8149-3969-e053-3a05fe0a2c94
|
64
|
|
Healthy CD4+ T lymphocytes are not affected by targeted therapies against the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia, file e309ade1-c41a-3969-e053-3a05fe0a2c94
|
62
|
|
Levels of miR-126 and miR-218 are elevated in ductal carcinoma in situ (DCIS) and inhibit malignant potential of DCIS derived cells, file e309ade1-df0c-3969-e053-3a05fe0a2c94
|
61
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|
Vav1 is necessary for PU.1 mediated upmodulation of miR-29b in acute myeloid leukaemia-derived cells, file e309ade2-dda3-3969-e053-3a05fe0a2c94
|
59
|
|
Phospholipase C-beta2 promotes mitosis and migration of human breast cancer-derived cells, file e309ade0-2199-3969-e053-3a05fe0a2c94
|
57
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|
Influence of physical exercise on microRNAs in skeletal muscle regeneration, aging and diseases, file e309ade1-c692-3969-e053-3a05fe0a2c94
|
55
|
|
Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/mTOR signaling, file e309ade1-9802-3969-e053-3a05fe0a2c94
|
52
|
|
Up-modulation of PLC-beta2 reduces the number and malignancy of triple-negative breast tumor cells with a CD133+/EpCAM+ phenotype: A promising target for preventing progression of TNBC, file e309ade1-7e53-3969-e053-3a05fe0a2c94
|
51
|
|
A network including PU.1, Vav1 and miR-142-3p sustains ATRA-induced differentiation of acute promyelocytic leukemia cells - a short report, file e309ade3-b4fe-3969-e053-3a05fe0a2c94
|
48
|
|
In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133high to CD133low phenotype and reduces the CD133-related invasiveness, file e309ade4-e973-3969-e053-3a05fe0a2c94
|
41
|
|
In triple negative breast tumor cells, PLC-beta 2 promotes the conversion of CD133(high) to CD133(low) phenotype and reduces the CD133-related invasiveness, file e309ade5-04a5-3969-e053-3a05fe0a2c94
|
39
|
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Clusterin enhances AKT2-mediated motility of normal and cancer prostate cells through a PTEN and PHLPP1 circuit, file e309ade4-1e40-3969-e053-3a05fe0a2c94
|
13
|
|
Targeting the PI3K/Akt/mTOR signaling pathway in B-precursor acute lymphoblastic leukemia and its therapeutic potential., file e309ade0-438d-3969-e053-3a05fe0a2c94
|
12
|
|
Nuclear translocation of active AKT is required for erythroid differentiation in erythropoietin treated K562 erythroleukemia cells., file e309ade0-285b-3969-e053-3a05fe0a2c94
|
10
|
|
Cytotoxic activity of the novel Akt inhibitor, MK-2206,
in T-cell acute lymphoblastic leukemia., file e309ade1-c789-3969-e053-3a05fe0a2c94
|
10
|
|
Vav1 Sustains the In Vitro Differentiation of Normal and Tumor Precursors to Insulin Producing Cells Induced by all-Trans Retinoic Acid (ATRA), file e309ade3-3d64-3969-e053-3a05fe0a2c94
|
10
|
|
PLC-β2 is highly expressed in breast cancer and is associated with a poor outcome: A study on tissue microarrays, file e309ade0-2b22-3969-e053-3a05fe0a2c94
|
9
|
|
Microparticle-loaded neonatal porcine Sertoli cells for cell-based
therapeutic and drug delivery system, file e309ade0-4045-3969-e053-3a05fe0a2c94
|
9
|
|
Multiple biological responses activated by nuclear protein kinase C., file e309ade0-2c99-3969-e053-3a05fe0a2c94
|
8
|
|
Mitogenic effects of Brazilian arthropod venom on isolated islet beta cells: In vitro morphologic ultrastructural and functional studies, file e309ade0-2257-3969-e053-3a05fe0a2c94
|
7
|
|
Lamin A is part of the internal nucleoskeleton of human erythroleukemia cells, file e309ade0-2c95-3969-e053-3a05fe0a2c94
|
7
|
|
Effects of simulated microgravity on the morphology and function of neonatal porcine cell clusters cultured with and without Sertoli cells, file e309ade0-9ca0-3969-e053-3a05fe0a2c94
|
7
|
|
Influence of the human immunodeficency virus type 1 Tat protein on the proliferation and differentiation of PC12 rat pheochromocytoma cells, file e309ade0-2141-3969-e053-3a05fe0a2c94
|
6
|
|
Discrete subcellular localization of phosphoinositidase C β, γ and δ in PC12 rat pheochromocytoma cells, file e309ade0-2142-3969-e053-3a05fe0a2c94
|
6
|
|
Analysis by confocal microscopy of the behavior of heat shock protein 70 within the nucleus and of a nuclear matrix polypeptide during prolonged heat shock response in HeLa cells, file e309ade0-2c97-3969-e053-3a05fe0a2c94
|
6
|
|
TRANSLOCATION OF Akt/PKB TO THE NUCLEUS OF OSTEOBLAST-LIKE MC3T3-E1 CELLS EXPOSED TO PROLIFERATIVE GROWTH FACTORS, file e309ade0-a003-3969-e053-3a05fe0a2c94
|
6
|
|
Chromosome spread for confocal microscopy, file e309ade1-b781-3969-e053-3a05fe0a2c94
|
6
|
|
RNA expression induced by cisplatin in an organ of Corti-derived immortalized cell line., file e309ade1-3ead-3969-e053-3a05fe0a2c94
|
5
|
|
null, file e309ade1-c557-3969-e053-3a05fe0a2c94
|
5
|
|
In vitro heat exposure induces a redistribution of nuclear matrix proteins in human K562 erythroleukemia cells, file e309ade0-2668-3969-e053-3a05fe0a2c94
|
4
|
|
Nuclear matrix-bound replicational sites detected in situ by 5-bromodeoxyuridine, file e309ade0-2671-3969-e053-3a05fe0a2c94
|
4
|
|
Enhanced resolution of specific chromosome and nuclear regions by reflectance laser scanning confocal microscopy, file e309ade0-26d9-3969-e053-3a05fe0a2c94
|
4
|
|
Phosphatidylinositol 3-kinase in HL-60 nuclei is bound to the nuclear matrix and increases during granulocytic differentiation, file e309ade0-2b25-3969-e053-3a05fe0a2c94
|
4
|
|
Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation., file e309ade1-c461-3969-e053-3a05fe0a2c94
|
4
|
|
Lipid phosphorylation in isolated rat liver nuclei. Synthesis of polyphosphoinositides at subnuclear level, file d5d0cd34-3557-4540-9ae0-a0b96ad36528
|
3
|
|
Threonine 308 phosphorylated form of Akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin, file e309ade0-2c90-3969-e053-3a05fe0a2c94
|
3
|
|
Mass spectrometry-based identification of Y745 of Vav1 as a tyrosine residue crucial in maturation of acute promyelocytic leukemia-derived cells, file e309ade0-3f3c-3969-e053-3a05fe0a2c94
|
3
|
|
null, file e309ade0-4dfe-3969-e053-3a05fe0a2c94
|
3
|
|
The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy, file e309ade1-c3f1-3969-e053-3a05fe0a2c94
|
3
|
|
Vav1 Sustains the In Vitro Differentiation of Normal and Tumor Precursors to Insulin Producing Cells Induced by all-Trans Retinoic Acid (ATRA), file f8788960-6c26-4297-ba49-b62e3d5b4ee3
|
3
|
|
Nuclear translocation of phosphatidylinositol 3-kinase in rat pheochromocytoma PC 12 cells after treatment with nerve growth factor., file e309ade0-20d9-3969-e053-3a05fe0a2c94
|
2
|
|
Nuclear scaffold proteins are differently sensitive to stabilizing treatment by heat or Cu++., file e309ade0-26bd-3969-e053-3a05fe0a2c94
|
2
|
|
Association of PI 3-K with tyrosine phosphorylated Vav is essential for its activity in neutrophil-like maturation of myeloid cells, file e309ade0-2b1a-3969-e053-3a05fe0a2c94
|
2
|
|
Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes, file e309ade0-2bcd-3969-e053-3a05fe0a2c94
|
2
|
|
Proliferating or differentiating stimuli act on different lipid-dependent signaling pathways in nuclei of human leukemia cells, file e309ade0-2c8f-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade0-2fca-3969-e053-3a05fe0a2c94
|
2
|
|
Inhibition of Akt signaling in hepatoma cells induces apoptotic cell death independent of Akt activation status., file e309ade0-ad25-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade0-af89-3969-e053-3a05fe0a2c94
|
2
|
|
An increased osteoprotegerin serum release characterizes the early onset of diabetes mellitus and may contribute to endothelial cell dysfunction, file e309ade1-ba3b-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade1-c114-3969-e053-3a05fe0a2c94
|
2
|
|
null, file e309ade1-c698-3969-e053-3a05fe0a2c94
|
2
|
|
A network including PU.1, Vav1 and miR-142-3p sustains ATRA-induced differentiation of acute promyelocytic leukemia cells - a short report, file e309ade2-dc0e-3969-e053-3a05fe0a2c94
|
2
|
|
High nuclear level of Vav1 is a positive prognostic factor in early invasive breast tumors: a role in modulating genes related to the efficiency of metastatic process, file d53d749d-8762-4f12-b123-280672647366
|
1
|
|
Immunocytochemical analysis of phosphatidylinositol-specific phospholipase C in PC12 cells: predominance of the δ isoform during neural differentiation, file e309ade0-2143-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-2198-3969-e053-3a05fe0a2c94
|
1
|
|
Accelerated functional maturation of isolated neonatal porcine cell clusters: In vitro and in vivo results in NOD mice, file e309ade0-2259-3969-e053-3a05fe0a2c94
|
1
|
|
Phosphoinositide 3-kinase is associated to the nucleus of HL-60 cells and is involved in their ATRA-induced granulocytic differentiation, file e309ade0-2261-3969-e053-3a05fe0a2c94
|
1
|
|
Lipid signaling and cell responses at the nuclear level., file e309ade0-2262-3969-e053-3a05fe0a2c94
|
1
|
|
Influence of different metal ions on the ultrastructure, biochemical properties, and protein localization of the K562 cell nuclear matrix., file e309ade0-2263-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-2379-3969-e053-3a05fe0a2c94
|
1
|
|
Phosphoinositide 3-kinase activity is essential for all-trans-retinoic acid-induced granulocytic differentiation of HL-60 cells., file e309ade0-257e-3969-e053-3a05fe0a2c94
|
1
|
|
PLC-beta2 monitors the drug-induced release of differentiation blockade in tumoral myeloid precursors, file e309ade0-25b3-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-26b4-3969-e053-3a05fe0a2c94
|
1
|
|
Prereplicative increase of nuclear matrix-bound DNA polymerase-alpha and primase activities in HeLa S3 cells following dilution of long-term cultures., file e309ade0-26b6-3969-e053-3a05fe0a2c94
|
1
|
|
Different concentrations of Mg++ ions affect nuclear matrix protein distribution during thermal stabilization of isolated nuclei, file e309ade0-26b8-3969-e053-3a05fe0a2c94
|
1
|
|
Intranuclear translocation of phospholipase C β2 during HL-60 myeloid differentiation, file e309ade0-26ba-3969-e053-3a05fe0a2c94
|
1
|
|
Changes of nuclear protein kinase C activity and isotype composition in PC12 cell proliferation and differentiation, file e309ade0-26bf-3969-e053-3a05fe0a2c94
|
1
|
|
The generation of lipid signaling molecules in the nucleus, file e309ade0-26c7-3969-e053-3a05fe0a2c94
|
1
|
|
Identification of PI-PLC beta 1, gamma 1, and delta 1 in rat liver: subcellular distribution and relationship to inositol lipid nuclear signalling., file e309ade0-2b27-3969-e053-3a05fe0a2c94
|
1
|
|
Sertoli cell-induced reversal of adult rat pancreatic Islet b-cells into fetal-like status: potential implications for Islet transplantation in type I diabetes mellitus., file e309ade0-2c92-3969-e053-3a05fe0a2c94
|
1
|
|
Spatial distribution of lamin A and B1 in the K562 cell nuclear matrix stabilized with metal ions, file e309ade0-2c94-3969-e053-3a05fe0a2c94
|
1
|
|
Inositol lipids in Friend erythroleukemia cells: evidence for changes in nuclear metabolism after differentiation, file e309ade0-36c4-3969-e053-3a05fe0a2c94
|
1
|
|
null, file e309ade0-a690-3969-e053-3a05fe0a2c94
|
1
|
| Totale |
1.860 |