Nome |
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Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis, file e309ade0-f854-3969-e053-3a05fe0a2c94
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298
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Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports, file e309ade2-140d-3969-e053-3a05fe0a2c94
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206
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Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus indicus R. Br, file e309ade0-61e0-3969-e053-3a05fe0a2c94
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173
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Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia, file e309ade2-4e76-3969-e053-3a05fe0a2c94
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151
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Moringa oleifera leaf extracts as multifunctional ingredients for “natural and organic” sunscreens and photoprotective preparations, file e309ade1-dc7e-3969-e053-3a05fe0a2c94
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146
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Ground state naïve pluripotent stem cells and CRISPR/Cas9 gene correction for β-thalassemia, file e309ade1-8cb9-3969-e053-3a05fe0a2c94
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141
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Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery, file e309ade0-b1f2-3969-e053-3a05fe0a2c94
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140
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An Aγ-globin G->A gene polymorphism associated with β(0)39 thalassemia globin gene and high fetal hemoglobin production, file e309ade1-7733-3969-e053-3a05fe0a2c94
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140
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Synthesis of platinum(II) and palladium(II) complexes with 9,9-dihexyl-4,5-diazafluorene and their in vivo antitumour activity against Hep3B xenografted mice, file e309ade1-375c-3969-e053-3a05fe0a2c94
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136
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Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions, file e309ade2-d99c-3969-e053-3a05fe0a2c94
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123
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Non-invasive fetal sex diagnosis in plasma of early weeks pregnants using droplet digital PCR, file e309ade3-1dbb-3969-e053-3a05fe0a2c94
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117
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BCL11A mRNA targeting by miR-210: A possible network regulating γ-globin gene expression, file e309ade1-8625-3969-e053-3a05fe0a2c94
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110
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Design, synthesis and biological activity of a novel Rutin analogue with improved lipid soluble properties, file e309ade4-8099-3969-e053-3a05fe0a2c94
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104
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Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review), file e309ade2-1508-3969-e053-3a05fe0a2c94
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99
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Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells, file e309ade2-4e78-3969-e053-3a05fe0a2c94
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97
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Purinergic signaling in scarring, file e309ade0-be28-3969-e053-3a05fe0a2c94
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96
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Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance, file e309ade3-a96d-3969-e053-3a05fe0a2c94
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94
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Postnatal and non-invasive prenatal detection of β-thalassemia mutations based on Taqman genotyping assays, file e309ade1-b707-3969-e053-3a05fe0a2c94
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92
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MicroRNAs and Long Non-coding RNAs in Genetic Diseases, file e309ade2-1ab8-3969-e053-3a05fe0a2c94
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87
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Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin, file e309ade0-a5be-3969-e053-3a05fe0a2c94
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83
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A validated cellular biobank for β-thalassemia, file e309ade0-ee58-3969-e053-3a05fe0a2c94
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78
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Differential Effects of Angelicin Analogues on NF-kB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells, file e309ade1-8832-3969-e053-3a05fe0a2c94
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72
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Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells, file e309ade0-ad71-3969-e053-3a05fe0a2c94
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70
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New insights into the Shwachman-Diamond Syndrome-related haematological disorder: Hyper-activation of mTOR and STAT3 in leukocytes, file e309ade0-ef51-3969-e053-3a05fe0a2c94
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70
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Molecular mechanism of action of trimethylangelicin derivatives as CFTR modulators, file e309ade4-3a26-3969-e053-3a05fe0a2c94
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69
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Recent trends in the gene therapy of β-thalassemia, file e309ade0-a34c-3969-e053-3a05fe0a2c94
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67
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Regulation of IL-8 gene expression in gliomas by microRNA miR-93, file e309ade0-a781-3969-e053-3a05fe0a2c94
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67
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Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor, file e309ade3-173a-3969-e053-3a05fe0a2c94
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67
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A peptide nucleic acid against microrna miR-145-5p enhances the expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells, file e309ade1-a84d-3969-e053-3a05fe0a2c94
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66
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Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene, file e309ade2-2c03-3969-e053-3a05fe0a2c94
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66
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Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA), file e309ade2-1293-3969-e053-3a05fe0a2c94
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65
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Efficient Delivery of MicroRNA and AntimiRNA Molecules Using an Argininocalix[4]arene Macrocycle, file e309ade2-84e3-3969-e053-3a05fe0a2c94
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64
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MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells, file e309ade2-d9f2-3969-e053-3a05fe0a2c94
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61
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Isothermal circular-strand-displacement polymerization of DNA and microRNA in digital microfluidic devices, file e309ade3-1d09-3969-e053-3a05fe0a2c94
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61
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Analytic and dynamic secretory profile of patient-derived cytokine-Induced killer cells, file e309ade1-81df-3969-e053-3a05fe0a2c94
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59
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Increased frequency of activated CD8+ T cell effectors in patients with psoriatic arthritis, file e309ade2-4392-3969-e053-3a05fe0a2c94
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59
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Enhancing the expression of CFTR using antisense molecules against MicroRNA miR-145-5p, file e309ade2-794c-3969-e053-3a05fe0a2c94
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59
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miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma, file e309ade0-de82-3969-e053-3a05fe0a2c94
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58
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Production of β-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous β039 thalassemia patients, file e309ade0-f426-3969-e053-3a05fe0a2c94
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58
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Peptide nucleic acid-based targeting of microRNAs: possible therapeutic applications for glioblastoma, file e309ade2-8d15-3969-e053-3a05fe0a2c94
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58
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Surface plasmon resonance analysis to detect the β+ IVSI-110 thalassemia mutation in circulating cell-free fetal DNA, file e309ade3-9e4c-3969-e053-3a05fe0a2c94
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58
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Purinergic Signaling During Immune Cell Trafficking, file e309ade3-aad5-3969-e053-3a05fe0a2c94
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58
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Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Ew trends in the development of miRNA therapeutic strategies in oncology, file e309ade0-e847-3969-e053-3a05fe0a2c94
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57
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Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology, file e309ade2-5220-3969-e053-3a05fe0a2c94
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57
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Pro‑apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro, file e309ade2-ef0e-3969-e053-3a05fe0a2c94
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57
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Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review), file e309ade0-b99e-3969-e053-3a05fe0a2c94
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56
|
Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae, file e309ade0-d970-3969-e053-3a05fe0a2c94
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56
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Immunomodulatory and anti-inflammatory activity in vitro and in vivo of a novel antimicrobial candidate, file e309ade1-2e0b-3969-e053-3a05fe0a2c94
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56
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Generation and characterization of a transgenic mouse carrying a functional human β-globin gene with the IVSI-6 thalassemia mutation, file e309ade0-a54c-3969-e053-3a05fe0a2c94
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55
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Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites, file e309ade0-ee55-3969-e053-3a05fe0a2c94
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54
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Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells, file e309ade2-d6a6-3969-e053-3a05fe0a2c94
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54
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Treatment of human airway epithelial Calu-3 cells with a peptide-nucleic acid (PNA) targeting the microRNA miR-101-3p is associated with increased expression of the cystic fibrosis Transmembrane Conductance Regulator () gene, file f8818e72-4359-45e8-bda1-5ad1b8cc735f
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54
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Cytokine-induced killer cells express CD39, CD38, CD203a, CD73 ectoenzymes and P1 adenosinergic receptors, file e309ade1-e319-3969-e053-3a05fe0a2c94
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53
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T cell hierarchy in the pathogenesis of psoriasis and associated cardiovascular comorbidities, file e309ade1-f0bf-3969-e053-3a05fe0a2c94
|
50
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MicroRNAs Modulate the Purinergic Signaling Network, file e309ade3-df51-3969-e053-3a05fe0a2c94
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49
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Polymerase-chain reaction: analysis of DNA/DNA hybridization by capillary electrophoresis, file e309ade0-f4a4-3969-e053-3a05fe0a2c94
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48
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Enzymatic Spermine Metabolites Induce Apoptosis Associated with Increase of p53, caspase-3 and miR-34a in Both Neuroblastoma Cells, SJNKP and the N-Myc-Amplified Form IMR5, file e309ade4-9397-3969-e053-3a05fe0a2c94
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48
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Tackling the COVID-19 “cytokine storm” with microRNA mimics directly targeting the 3’UTR of pro-inflammatory mRNAs, file e309ade3-3cc7-3969-e053-3a05fe0a2c94
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47
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Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line, file e309ade2-82f2-3969-e053-3a05fe0a2c94
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46
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A Molecular Signature associated with prolonged survival in Glioblastoma patients treated with Regorafenib, file e309ade4-8caf-3969-e053-3a05fe0a2c94
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46
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Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis, file e309ade2-d08c-3969-e053-3a05fe0a2c94
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43
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Sex-specific transcriptional profiles identified in β-thalassemia patients, file e309ade2-e0d0-3969-e053-3a05fe0a2c94
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42
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Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma, file e309ade2-15b5-3969-e053-3a05fe0a2c94
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41
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Circulating microRNAs and liquid biopsy: murine xenograft models for technical validation of clinical protocols, file e309ade4-e1ec-3969-e053-3a05fe0a2c94
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41
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Antiproliferative activity of essential oils derived from plants belonging to the Magnoliophyta division, file e309ade4-764f-3969-e053-3a05fe0a2c94
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40
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Theranostics of Genetic Diseases, file e309ade2-4e7c-3969-e053-3a05fe0a2c94
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36
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Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters, file e309ade2-5134-3969-e053-3a05fe0a2c94
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36
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UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation, file e309ade2-1ad9-3969-e053-3a05fe0a2c94
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35
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Sequencing of an upstream region of the human HLA-DRA gene containing X' and Y' boxes, file e309ade2-3b0a-3969-e053-3a05fe0a2c94
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34
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Preparation of anti-miR PNAs for drug development and nanomedicine, file e309ade5-8893-3969-e053-3a05fe0a2c94
|
32
|
Bis(dimethylsulfoxide)carbonateplatinum(II), a new synthon for a low-impact, versatile synthetic route to anticancer Pt carboxylates, file e309ade3-ff68-3969-e053-3a05fe0a2c94
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30
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Synthesis and characterization of Pt complexes containing dichloroacetate (DCA), designed for dual anticancer action, file e309ade3-a50d-3969-e053-3a05fe0a2c94
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28
|
Expression of γ-globin genes in β-thalassemia patients treated with sirolimus: results from a pilot clinical trial (Sirthalaclin), file 330010a8-57ab-464b-ac76-8393bc420f74
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27
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Teaching during COVID-19 pandemic in practical laboratory classes of applied biochemistry and pharmacology: A validated fast and simple protocol for detection of SARS-CoV-2 Spike sequences, file 54a3abb9-d553-400e-b399-8faf8b175616
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27
|
Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis, file e309ade4-9951-3969-e053-3a05fe0a2c94
|
25
|
Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein, file e309ade4-a21c-3969-e053-3a05fe0a2c94
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22
|
A PNA-based masking strategy for CFTR upregulation by targeting miR-145-5p binding sites of CFTR mRNA, file e309ade4-e1d6-3969-e053-3a05fe0a2c94
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22
|
Palladacyclopentadienyl complexes bearing purine-based N-heterocyclic carbenes: A new class of promising antiproliferative agents against human ovarian cancer, file e309ade3-9c36-3969-e053-3a05fe0a2c94
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21
|
A peptide nucleic acid (PNA) masking the miR-145-5p binding site of the 3’UTR of the cystic fibrosis transmembrane conductance regulator (CFTR) mRNA enhances CFTR expression in Calu-3 cells, file e309ade5-219c-3969-e053-3a05fe0a2c94
|
20
|
Sex-specific transcriptional profiles identified in β-thalassemia patients, file e309ade4-c1c5-3969-e053-3a05fe0a2c94
|
19
|
Increased frequency of activated CD8+ T cell effectors in patients with psoriatic arthritis, file e309ade2-4393-3969-e053-3a05fe0a2c94
|
17
|
Evaluation of the mutagenic, antimutagenic and antiproliferative potential of Croton lechleri (Muell. Arg.) latex., file e309ade0-f54f-3969-e053-3a05fe0a2c94
|
16
|
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening, file e309ade2-d995-3969-e053-3a05fe0a2c94
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16
|
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222, file e309ade3-1797-3969-e053-3a05fe0a2c94
|
16
|
MicroRNAs Modulate the Purinergic Signaling Network, file e309ade3-f8df-3969-e053-3a05fe0a2c94
|
16
|
A Molecular Signature associated with prolonged survival in Glioblastoma patients treated with Regorafenib, file e309ade5-1733-3969-e053-3a05fe0a2c94
|
16
|
Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation., file e309ade0-b02c-3969-e053-3a05fe0a2c94
|
15
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β-Sitosterol reduces the expression of chemotactic cytokine genes in cystic fibrosis bronchial epithelial cells, file e309ade1-69e2-3969-e053-3a05fe0a2c94
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14
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Epigenetic changes as a common trigger of muscle weakness in congenital myopathies, file e309ade3-17ce-3969-e053-3a05fe0a2c94
|
14
|
Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β039-Globin Gene Editing and Induction of Fetal Hemoglobin, file 9d5c4855-ca44-4b1e-81e0-0497d5378d9a
|
13
|
Efficient CRISPR-Cas9-based genome editing of β-globin gene on erythroid cells from homozygous β039-thalassemia patients, file 9da7183c-325f-47c5-ad31-8c0adf3f55bf
|
13
|
Down-regulation of LYAR is associated with induction of fetal hemoglobin in mithramycin-treated erythroid cells, file e309ade5-2cca-3969-e053-3a05fe0a2c94
|
13
|
Therapy for Cystic Fibrosis Caused by Nonsense Mutations, file e309ade0-e68c-3969-e053-3a05fe0a2c94
|
12
|
Novel lipidized derivatives of the bioflavonoid hesperidin: Dermatological, cosmetic and chemopreventive applications, file e309ade2-0b9e-3969-e053-3a05fe0a2c94
|
12
|
Synthesis and biological evaluation of new antitubulin agents containing 2-(30,40,50-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold, file e309ade2-9b91-3969-e053-3a05fe0a2c94
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11
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A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1, file e309ade4-d2e9-3969-e053-3a05fe0a2c94
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11
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Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines, file e309ade0-301b-3969-e053-3a05fe0a2c94
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10
|
Trans-Resveratrol in nutraceuticals: issuses in retail quality and effectiveness, file e309ade0-3833-3969-e053-3a05fe0a2c94
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10
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Programmable interactions of functionalized single bioparticles in a dielectrophoresis-based microarray chip., file e309ade0-4946-3969-e053-3a05fe0a2c94
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10
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Correlation between Slug transcription factor and miR-221 in MDA-MB-231 breast cancer cells, file e309ade0-9b56-3969-e053-3a05fe0a2c94
|
10
|
Totale |
5.872 |