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EnglishOatients with thalassemia major, intermedia or double eterozygous with sickle cell disease are exposed to a major risk of developing hepatocellular carcinoma (HCC). Transfusion-transmitted viral infections and long standing iron overload represent principal carcinogenic risk factors. Every effort should be made to prevent tumor development, whose prognosis is usually dismal, or at least to make an early diagnosis. Screening should be performed regulary by means of ultra-sonography (US) and measurement of serum alpha-fetoprotein (AFP)
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http://hdl.handle.net/11392/536145| Titolo: | The risk of Hepatocellular carcinoma in patients with thalassemia. A review. |
| Autori interni: | BORGNA, Caterina |
| Data di pubblicazione: | 2009 |
| Rivista: | ACTA MEDICA MEDITERRANEA |
| Abstract: | Oatients with thalassemia major, intermedia or double eterozygous with sickle cell disease are exposed to a major risk of developing hepatocellular carcinoma (HCC). Transfusion-transmitted viral infections and long standing iron overload represent principal carcinogenic risk factors. Every effort should be made to prevent tumor development, whose prognosis is usually dismal, or at least to make an early diagnosis. Screening should be performed regulary by means of ultra-sonography (US) and measurement of serum alpha-fetoprotein (AFP) |
| Handle: | http://hdl.handle.net/11392/536145 |
| Appare nelle tipologie: | 03.1 Articolo su rivista |
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