Oatients with thalassemia major, intermedia or double eterozygous with sickle cell disease are exposed to a major risk of developing hepatocellular carcinoma (HCC). Transfusion-transmitted viral infections and long standing iron overload represent principal carcinogenic risk factors. Every effort should be made to prevent tumor development, whose prognosis is usually dismal, or at least to make an early diagnosis. Screening should be performed regulary by means of ultra-sonography (US) and measurement of serum alpha-fetoprotein (AFP)

The risk of Hepatocellular carcinoma in patients with thalassemia. A review.

BORGNA, Caterina
2009

Abstract

Oatients with thalassemia major, intermedia or double eterozygous with sickle cell disease are exposed to a major risk of developing hepatocellular carcinoma (HCC). Transfusion-transmitted viral infections and long standing iron overload represent principal carcinogenic risk factors. Every effort should be made to prevent tumor development, whose prognosis is usually dismal, or at least to make an early diagnosis. Screening should be performed regulary by means of ultra-sonography (US) and measurement of serum alpha-fetoprotein (AFP)
2009
E., Fabbri; G., Guerrini; Borgna, Caterina
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/536145
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 2
social impact