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EnglishMethacholine (MCH) is used to perform the bronchial challenge test for the diagnosis of asthma where it is necessary to determine if an individual has hyper-responsive airways. The aim of this work was to develop a new method for MCH challenge test using pre-metered respirable MCH powders at different doses for performing brochial challenge studies. The availability of a series of pre-metered doses gives greater control on aerosolized dose and fine particle dose (respirable dose), improving the accuracy and repeatability of the test. A dosimetric challenge test, comparing MCH dry powder and MCH solution for asthma detection, was performed in eighteen subjects.
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| Titolo: | A Clinical Study of a Methacholine Dry Powder for the Bronchial Challenge Test | |
| Autori: | ||
| Data di pubblicazione: | 2008 | |
| Abstract: | Methacholine (MCH) is used to perform the bronchial challenge test for the diagnosis of asthma where it is necessary to determine if an individual has hyper-responsive airways. The aim of this work was to develop a new method for MCH challenge test using pre-metered respirable MCH powders at different doses for performing brochial challenge studies. The availability of a series of pre-metered doses gives greater control on aerosolized dose and fine particle dose (respirable dose), improving the accuracy and repeatability of the test. A dosimetric challenge test, comparing MCH dry powder and MCH solution for asthma detection, was performed in eighteen subjects. | |
| Handle: | http://hdl.handle.net/11392/534041 | |
| ISBN: | 9781933722214 9781933722221 9781933722238 | |
| Appare nelle tipologie: | 04.2 Contributi in atti di convegno (in Volume) |
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