In this communication the crystallographic structures of two protesome 20s inhibitors are reported, together with a conformational study of the molecules in the solid state, in vacuum and in a polar environment which is in turn the basis for a docking study of such inhibitors to the crystallographic structure of the proteasome.
New class of proteasome 20S inhibitors: a crystallographic and molecular modelling study
FERRETTI, Valeria;PRETTO, Loretta;MARASTONI, Mauro;BALDISSEROTTO, Anna;GAVIOLI, Riccardo
2005
Abstract
In this communication the crystallographic structures of two protesome 20s inhibitors are reported, together with a conformational study of the molecules in the solid state, in vacuum and in a polar environment which is in turn the basis for a docking study of such inhibitors to the crystallographic structure of the proteasome.File in questo prodotto:
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