Three different classes of vectors can be derived from HSV-1: replication-competent attenuated vectors, replication-incompetent recombinant vectors and defective helper-dependent vectors known as amplicons. This chapter highlights the current knowledge concerning design, construction and recent applications, as well as the potential and current limitations of the three different classes of HSV-1-based vectors.

Herpesvirus-based vectors for gene transfer, gene therapy and the development of novel vaccines

MANSERVIGI, Roberto;ARGNANI, Rafaela;MARCONI, Peggy Carla Raffaella;
2007

Abstract

Three different classes of vectors can be derived from HSV-1: replication-competent attenuated vectors, replication-incompetent recombinant vectors and defective helper-dependent vectors known as amplicons. This chapter highlights the current knowledge concerning design, construction and recent applications, as well as the potential and current limitations of the three different classes of HSV-1-based vectors.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/522776
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