Resistance (Raw) measurement is not included in the guidelines for the diagnosis and management of asthma. Actually, spirometry is more widely available and less expensive and Raw measurement in the body plethysmograph can be difficult for some patients. Devices to measure oscillatory resistance are now available.The forced oscillation technique is a non-invasive method requiring no active contribution from the subject. We aimed to assess the utility of respiratory resistance measurement and the correlation with spirometric data in asthmatic patients. We studied 15 asthmatic subjects, (8M,7F,mean age 43,8 4,8) from our outpatients clinic, before and after the administration of bronchodilator (salbutamol 200mcg). A significant negative correlation has been found between FEV1 and Raw both before and after salbutamol administration (p=0,02 and 0,05 respectively). A significant negative correlation has been found between FEF 25-75 and Raw before bronchodilation (p=0,008) but not after. No correlation has been found between MEF25 and Raw. Our data suggest that Raw measurement can be used in detection of airway obstruction and reversibility and can sometimes have potential advantages in the assessment of patients unable to perform accettable forced expiration curve (elderly persons, children) or when the spirometry is contraindicated (unstable cardiovascular status, recent thoracic or abdominal surgery...).
Raw Measurements: Are They Useful in Asthma?
D'EMILIO, Vittorio;CONTOLI, Marco;CIACCIA, Adalberto;COGO, Annaluisa
2004
Abstract
Resistance (Raw) measurement is not included in the guidelines for the diagnosis and management of asthma. Actually, spirometry is more widely available and less expensive and Raw measurement in the body plethysmograph can be difficult for some patients. Devices to measure oscillatory resistance are now available.The forced oscillation technique is a non-invasive method requiring no active contribution from the subject. We aimed to assess the utility of respiratory resistance measurement and the correlation with spirometric data in asthmatic patients. We studied 15 asthmatic subjects, (8M,7F,mean age 43,8 4,8) from our outpatients clinic, before and after the administration of bronchodilator (salbutamol 200mcg). A significant negative correlation has been found between FEV1 and Raw both before and after salbutamol administration (p=0,02 and 0,05 respectively). A significant negative correlation has been found between FEF 25-75 and Raw before bronchodilation (p=0,008) but not after. No correlation has been found between MEF25 and Raw. Our data suggest that Raw measurement can be used in detection of airway obstruction and reversibility and can sometimes have potential advantages in the assessment of patients unable to perform accettable forced expiration curve (elderly persons, children) or when the spirometry is contraindicated (unstable cardiovascular status, recent thoracic or abdominal surgery...).I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
