The present invention relates to a metal complex of the general formula MX n (Q)L m wherein - M is a transition metal ion; - X is nitrido or oxo; - Q is a tridentate ligand comprising a peptide P, wherein P contains from 1 to 20 amino acids and optionally complexing moieties and includes a tridentate complexing sequence AB comprising at least three metal complexing donor atoms, wherein - A and B are independently an amino acid or a complexing moiety and are linked by an amide bond, wherein the metal complexing donor atoms of AB consist of either two sulfur atoms and one nitrogen atom, or one sulfur atom and two nitrogen atoms in a sequence selected from SNS, SNN, and NNS, wherein the central nitrogen in the sequence SNS, SNN, and NNS is an amide bond nitrogen; - L is a co-ligand selected from the group consisting of phosphine, thiol, arsine, carbonyl, and halide ligand; - n is 0 or 1 and m = 1 or 3, with the proviso that when n = 0, m = 3, and that when n = 1, m = 1.

Radioactive metal complexes comprising a tridentate complexing sequence

DUATTI, Adriano;UCCELLI, Licia;BOSCHI, Alessandra;
2008

Abstract

The present invention relates to a metal complex of the general formula MX n (Q)L m wherein - M is a transition metal ion; - X is nitrido or oxo; - Q is a tridentate ligand comprising a peptide P, wherein P contains from 1 to 20 amino acids and optionally complexing moieties and includes a tridentate complexing sequence AB comprising at least three metal complexing donor atoms, wherein - A and B are independently an amino acid or a complexing moiety and are linked by an amide bond, wherein the metal complexing donor atoms of AB consist of either two sulfur atoms and one nitrogen atom, or one sulfur atom and two nitrogen atoms in a sequence selected from SNS, SNN, and NNS, wherein the central nitrogen in the sequence SNS, SNN, and NNS is an amide bond nitrogen; - L is a co-ligand selected from the group consisting of phosphine, thiol, arsine, carbonyl, and halide ligand; - n is 0 or 1 and m = 1 or 3, with the proviso that when n = 0, m = 3, and that when n = 1, m = 1.
2008
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/518058
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact