A convergent one-pot construction of functinalized pyrrolidine ring sistems has been developed.The method is based on a tandem Michael reaction initiated by an intramolecular conjugate addition of a nitrogen nucleophile to an electophilic olefin followed by trapping of the generated enolate by a bult-in unsaturated acceptor.

A new approach to kainoids through tandem Michael reaction methodology: application to the enantioselective synthesis of (+) and (-)-a-Allokainic acid and to the formal synthesis of (-)-a-Kainic acid. A. Barco, S. Benetti, A.Casolari, G.P. Pollini, G. Spalluto, V. Zanirato ,

BARCO, Achille;BENETTI, Simonetta;CASOLARI, Alberto;POLLINI, Gian Piero;ZANIRATO, Vinicio
1992

Abstract

A convergent one-pot construction of functinalized pyrrolidine ring sistems has been developed.The method is based on a tandem Michael reaction initiated by an intramolecular conjugate addition of a nitrogen nucleophile to an electophilic olefin followed by trapping of the generated enolate by a bult-in unsaturated acceptor.
Barco, Achille; Benetti, Simonetta; Spalluto, G.; Casolari, Alberto; Pollini, Gian Piero; Zanirato, Vinicio
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11392/460295
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 85
  • ???jsp.display-item.citation.isi??? 86
social impact