Two major neuronal populations were revealed in rat dorsal root ganglia, immunoreactive for either peripherin, or neurofilament triplet proteins (adult L2 ganglia: 66.2% and 25.6%, mainly small and large diameter cells, respectively), together with a minor, doubleimmunostained population (L2: 8.1%, mainly intermediate-size neurons). After capsaicin treatment, a striking expansion in the latter population was seen (L2: 22.0%) together with a sigmficant increase in size, restricted to the same population and the (remaining) peripherin-only immunoreactlve neurons. Calcitonin gene-related peptide (CGRP) immunoreactivity was revealed in neurons of all 3 groups, in both normal and capsaicin-treated rats.
Neuronal intermediate filaments in rat dorsal root ganglia: differential distribution of peripherin- and neurofilament proteins-immunoreactivity and effect of capsaicin.
ABELLI, Luigi;
1990
Abstract
Two major neuronal populations were revealed in rat dorsal root ganglia, immunoreactive for either peripherin, or neurofilament triplet proteins (adult L2 ganglia: 66.2% and 25.6%, mainly small and large diameter cells, respectively), together with a minor, doubleimmunostained population (L2: 8.1%, mainly intermediate-size neurons). After capsaicin treatment, a striking expansion in the latter population was seen (L2: 22.0%) together with a sigmficant increase in size, restricted to the same population and the (remaining) peripherin-only immunoreactlve neurons. Calcitonin gene-related peptide (CGRP) immunoreactivity was revealed in neurons of all 3 groups, in both normal and capsaicin-treated rats.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.